LOCUS       CM000175               35956 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 7, whole genome shotgun
            sequence.
ACCESSION   CM000175
VERSION     CM000175.1
KEYWORDS    .
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-23 15:43:59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 63703
            Orig. end    :: 99659
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..35956
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:25956]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..25956
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..35956
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..35956
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="3"
                     /subregion_numbers="4"
                     /tool="antismash"
     gene            complement(<249..>2295)
                     /locus_tag="AFUA_7G00230"
                     /old_locus_tag="Afu7g00230"
     mRNA            complement(join(<249..1070,1139..1595,1662..2092,
                     2122..>2295))
                     /locus_tag="AFUA_7G00230"
                     /note="transcript AFUA_7G00230A"
                     /old_locus_tag="Afu7g00230"
                     /product="MFS multidrug transporter, putative"
     CDS             complement(join(249..1070,1139..1595,1662..2092,
                     2122..2295))
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 119.8; E-value: 1.9e-36)"
                     /gene_kind="transport"
                     /locus_tag="AFUA_7G00230"
                     /note="encoded by transcript AFUA_7G00230A; GB:CAG86930.1:
                     unnamed protein product; similar to CA4635|IPF1524 Candida
                     albicans IPF1524, hypothetical start {Debaryomyces hansenii
                     CBS767;}; GO_component: GO:0005887 - integral to plasma
                     membrane; GO_function: GO:0015239 - multidrug transporter
                     activity; GO_process: GO:0009636 - response to toxin"
                     /old_locus_tag="Afu7g00230"
                     /product="MFS multidrug transporter, putative"
                     /protein_id="EAL84868.1"
                     /transl_table=1
                     /translation="MLSAWGTGEHLDTSRLARTHSNPPWANQMAGDTRLRGESPTVLGE
                     TADTISSRSGTSNYPKLKSSNFRRICQRPLLVFLGWLTQISTIIPLRINARARRFDRAT
                     TMEEKASNTDSTAPAHPNSRLPQQSISSAPVLAQGPKTECTEKGTATEGSLTDPACQAD
                     DDSEIVKWDGENDPELPLNWPASKKWRNVVMVSALTFVTPFASSMFAPAINQVMVEMGT
                     SNRDIGSFGVSIYLLGYAFGPLVLAPCSELYGRLIVYHISAALFILCNVACALSISMPM
                     LIIVRFLTGLVGAAPLTIGPGTVADCFRQEQRGRAMAIWTMPVLLGPCLGPAIGAYVSR
                     SLGWRWNFWLLIIVSGAVSLFCLVFQRETHAPTLLKRKAARLRKSTGNPNIRHDDRTTI
                     SRSQLITTSIVRPVKMLFLSPVVFGLSLLTAVAYGTLYLFFTTVTDVFASRYGIITNVG
                     LIYLGCGCGQFAGLFILGLVSDAIVRRAARGGEMKPEYRLPPTILGGSMIPIGLLIYGW
                     TAEYRVFWFVPVLGTFLIGFGMITVFTPVGTYLVDAFPMYAASATAANTVFRSVGGAFL
                     PLAGPRMYSSLGQGWGNTLLAGISLLMMGMIFMSLKYGERLRTHPKYQIKL"
     PFAM_domain     complement(join(402..1070,1139..1595,1662..1678))
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00230_0017"
                     /evalue="1.40E-46"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="AFUA_7G00230"
                     /locus_tag="AFUA_7G00230"
                     /protein_end="577"
                     /protein_start="196"
                     /score="159.2"
                     /tool="antismash"
                     /translation="ALTFVTPFASSMFAPAINQVMVEMGTSNRDIGSFGVSIYLLGYAF
                     GPLVLAPCSELYGRLIVYHISAALFILCNVACALSISMPMLIIVRFLTGLVGAAPLTIG
                     PGTVADCFRQEQRGRAMAIWTMPVLLGPCLGPAIGAYVSRSLGWRWNFWLLIIVSGAVS
                     LFCLVFQRETHAPTLLKRKAARLRKSTGNPNIRHDDRTTISRSQLITTSIVRPVKMLFL
                     SPVVFGLSLLTAVAYGTLYLFFTTVTDVFASRYGIITNVGLIYLGCGCGQFAGLFILGL
                     VSDAIVRRAARGGEMKPEYRLPPTILGGSMIPIGLLIYGWTAEYRVFWFVPVLGTFLIG
                     FGMITVFTPVGTYLVDAFPMYAASATAANTVFRSVGGAFLP"
     promoter        2245..2625
                     /locus_tag="AFUA_7G00230"
                     /locus_tag="AFUA_7G00240"
                     /note="bidirectional promoter"
                     /seq="GCCAGCCTGCTAGTATCGAGATGCTCTCCTGTCCCCCATGCTGACAGCATTGC
                     CCTTTGTGTCCCCGCGAACCCACTCCCTCAGGATACTGATTTGGGCGAAAGCCTCACGT
                     CGGGGAGGCATCCCGGCACTGACCCTGACGACCAATACCCCTGAGCCCCAACTCACTGA
                     CCCCTTGCCGACAGAAACCATGGCTCACTATCCTCAGCATATCTCGGCTCGGGCCGGAG
                     GTGGTTATAAGTATTATAGCATCAACCATTTCTGACGGACACACAGGCTCCCCTGGTGC
                     GGTCATTTTAGCCCGTCTCGTGCTTGGAAACCGTTGCCAATATGGGAGAGATATGTCCT
                     CGTAGGGAGGATTTCGATATTGATTACATTCTC"
                     /tool="antismash"
     gene            <2576..>5111
                     /locus_tag="AFUA_7G00240"
                     /old_locus_tag="Afu7g00240"
     mRNA            join(<2576..2666,2735..3341,3401..3980,4017..4838,
                     4908..>5111)
                     /locus_tag="AFUA_7G00240"
                     /note="transcript AFUA_7G00240A"
                     /old_locus_tag="Afu7g00240"
                     /product="beta-glucosidase, putative"
     CDS             join(2576..2666,2735..3341,3401..3980,4017..4838,
                     4908..5111)
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /locus_tag="AFUA_7G00240"
                     /note="encoded by transcript AFUA_7G00240A; similar to
                     Beta-glucosidase (Swiss-Prot:P27034) [Agrobacterium
                     tumefaciens] similar to Beta-glucosidase
                     (Swiss-Prot:P07337) [Kluyveromyces marxianus]; GO_function:
                     GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl
                     compounds; GO_process: GO:0005975 - carbohydrate metabolic
                     process"
                     /old_locus_tag="Afu7g00240"
                     /product="beta-glucosidase, putative"
                     /protein_id="EAL84867.1"
                     /transl_table=1
                     /translation="MGEICPRREDFDIDYILKNASLLEKVSLLAGYDFWHTAPLPRFNV
                     PSVRVSDGPNGVRGTKFFDGVRAACLPCGTGLAATWDQSLLYDAGVLIGQECLAKGAHC
                     WLVPTVCIQRSPLGGRGFESFAEDPYATGKLAAAYIRGAQSTGVISTIKHFAANDQEHE
                     RISVNAVMSERALREVHLLPFQIAIADSAPGAVMTCYNKVNGQHLSESKEMLDGLLRRE
                     WGWKGLIMSDWFGTYSTAEALNAGLGLEMPGTTRLRGPLLELAISSRKVSRATLDERAR
                     TVLEFVQRARKAEVSAVESTRDFPEDRRLNRKLAADSIVLLKNESGLLPLNPQTLTSVA
                     LIGPNMKTAAFCGGGSASLQPYYSTSPYQGITSQLPPGVEVLYETGATSYAFIPELEAS
                     EVRTPEGQPGLRMRFYRDPPSVQERRVLMGFSNPELDRLFYADIEAELIAPATGPFQFG
                     LAVYGSASLFLNDQLIIDNTTVQRGGTFFFGKGTLEETATVDLVQGQSYQIKVQFASGP
                     SSKLVKPGVVNFGGGAGRLGMVQVVDPERAIARAVEAAKRADITILGVGLTRDHESEGF
                     DRSHMDLPPAVASLVTAVLDVAPDAILLTQSGTPFSMLPWADLVKTHLHAWFGGNELGN
                     GIADVLFGVVNPSGKLPLSFPRRIEDTPTYLNFGSERGQVTYGEGIYVGYKLLRKSPTS
                     CALSIRARFVVHLLCVLRFDGRHRVRYTECSKLGRRGRSGSSPAVYRGRSNNVVNRTSH
                     QGAQRISKGGFAAR"
     PFAM_domain     join(2848..3341,3401..3557)
                     /aSDomain="Glyco_hydro_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00933.24"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /description="Glycosyl hydrolase family 3 N terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00240_0018"
                     /evalue="4.90E-41"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /label="AFUA_7G00240"
                     /locus_tag="AFUA_7G00240"
                     /protein_end="285"
                     /protein_start="68"
                     /score="141.3"
                     /tool="antismash"
                     /translation="ACLPCGTGLAATWDQSLLYDAGVLIGQECLAKGAHCWLVPTVCIQ
                     RSPLGGRGFESFAEDPYATGKLAAAYIRGAQSTGVISTIKHFAANDQEHERISVNAVMS
                     ERALREVHLLPFQIAIADSAPGAVMTCYNKVNGQHLSESKEMLDGLLRREWGWKGLIMS
                     DWFGTYSTAEALNAGLGLEMPGTTRLRGPLLELAISSRKVSRATLDERARTVLE"
     PFAM_domain     join(3657..3980,4017..4793)
                     /aSDomain="Glyco_hydro_3_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01915.25"
                     /db_xref="GO:0004553"
                     /db_xref="GO:0005975"
                     /description="Glycosyl hydrolase family 3 C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00240_0019"
                     /evalue="1.10E-52"
                     /gene_ontologies="GO:0004553: hydrolase activity,
                     hydrolyzing O-glycosyl compounds"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /label="AFUA_7G00240"
                     /locus_tag="AFUA_7G00240"
                     /protein_end="685"
                     /protein_start="318"
                     /score="179.0"
                     /tool="antismash"
                     /translation="IVLLKNESGLLPLNPQTLTSVALIGPNMKTAAFCGGGSASLQPYY
                     STSPYQGITSQLPPGVEVLYETGATSYAFIPELEASEVRTPEGQPGLRMRFYRDPPSVQ
                     ERRVLMGFSNPELDRLFYADIEAELIAPATGPFQFGLAVYGSASLFLNDQLIIDNTTVQ
                     RGGTFFFGKGTLEETATVDLVQGQSYQIKVQFASGPSSKLVKPGVVNFGGGAGRLGMVQ
                     VVDPERAIARAVEAAKRADITILGVGLTRDHESEGFDRSHMDLPPAVASLVTAVLDVAP
                     DAILLTQSGTPFSMLPWADLVKTHLHAWFGGNELGNGIADVLFGVVNPSGKLPLSFPRR
                     IEDTPTYLNFGSERGQVTYGEGIYVGY"
     promoter        5517..6567
                     /locus_tag="AFUA_7G00250"
                     /seq="CAGGATGACCTGGGAACTCAACAGTTGTTTCCGTCTCGGGAAAATTGCCTGAA
                     TCCCCATTTGTAACGAATGGCTGCTCCAGTGTGCCTCTGTTCTCTGAGCGATCCGATTG
                     AGCCGTCCGACCGTGGCTTGGCTTAAATAGCCGGGAGCCACGTCTTTCCACTCCTCTGT
                     AAATCGTCGGCCGTCGCGTCTGGGTGGATCTGGTAATCCGAACTCGGGCGAGTAGGCGC
                     GAGAGCTCTATGCCGTTGCTGGTCGACGGCTTGTCGGAGTTGCTGTATTAAAGTAAAAG
                     GATGTAGGCCACAGAAGACTTTAGAATAGCTTAGTTGCCTGCCTTCACCGTGGTTCGGC
                     AGACGTCGGGCTGCGTGATCTAAGATGAACTGTACAGAGTAATCATTCACTATCCACCT
                     GTCTGCCCTCTTAGCCTGGCTAGCGGTATTATACTATGGAAATTTATAATACACAATCA
                     AAATACTACGACAGCTGAGGAAACCACTGATAAACCCATCACCAACTCACTATCCAGCA
                     AGGTGGATTGGTACCCCTACCGAATTATTGAGATAGTGGATGAATATGATAGGAATACT
                     TTTAAGCCCTCACCAAGTCCGACTTACACCATTGGCGTTTATCCATGACACAGTCCATT
                     ATACCGAGTTAGCGTAGGTTAGGCACTGTGCGCTGTCCGCGTCTTTTGTCCAGTCTCCT
                     GGAGGATCGTCCGGGCTCGTCTGCAATGGATGGTTTTCGGCGAATGGCAGGCTGGGTCA
                     AGACGCCGTAATGCAGGCATGACATGAGATCAAATGTCCTATCCCTGTCCATACATAGT
                     CCAGCGAAGTCTGTCTGTAATCTGTATCGTACTAGCGGCGTGGGAGTCACTAGTCGGTC
                     TTTTATTGAAGCCTGACCTCCCAACTCCCAACAGCTCCTGTTCTCCTCATCCTACCTCG
                     TCTCCTATACCCTACTCGCATTCATTCATTCTCAGATTTGATACTCCGAGCTGCCCACC
                     AATATGCGTGAAATTGTGAGTCCACTCGCTGTCTTTGGAACGGCCTGCCGTCGA"
                     /tool="antismash"
     gene            <6518..>8245
                     /locus_tag="AFUA_7G00250"
                     /old_locus_tag="Afu7g00250"
     mRNA            join(<6518..6529,6606..6629,6694..6719,6775..6816,
                     6866..7376,7426..7760,7849..>8245)
                     /locus_tag="AFUA_7G00250"
                     /note="transcript AFUA_7G00250A"
                     /old_locus_tag="Afu7g00250"
                     /product="tubulin beta subunit"
     CDS             join(6518..6529,6606..6629,6694..6719,6775..6816,
                     6866..7376,7426..7760,7849..8245)
                     /codon_start=1
                     /locus_tag="AFUA_7G00250"
                     /note="encoded by transcript AFUA_7G00250A; GO_component:
                     GO:0005816 - spindle pole body; GO_component: GO:0005827 -
                     polar microtubule; GO_component: GO:0005828 - kinetochore
                     microtubule; GO_component: GO:0005880 - nuclear
                     microtubule; GO_component: GO:0005881 - cytoplasmic
                     microtubule; GO_function: GO:0005200 - structural
                     constituent of cytoskeleton; GO_process: GO:0000065 -
                     nuclear migration (sensu Saccharomyces); GO_process:
                     GO:0000070 - mitotic sister chromatid segregation;
                     GO_process: GO:0000743 - nuclear migration during
                     conjugation with cellular fusion; GO_process: GO:0007061 -
                     homologous chromosome segregation"
                     /old_locus_tag="Afu7g00250"
                     /product="tubulin beta subunit"
                     /protein_id="EAL84866.1"
                     /transl_table=1
                     /translation="MREIVHLQTGQCGNQVGAAFWQTISSEHGLDESGLCNASSDQQLE
                     RMNVYFNEVGNSKYVPRAVLVDLEPGTMDAIRSGPHGALFRPDNFVFGQSSAGNNWAKG
                     HYTEGAELVDQVIDVVRREAESCDYLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRM
                     MATFSVLPSPKVSDTVVEPYNATLSVHQLVEHADETFCIDNEALYDICTRTLKLSSPSY
                     GDLNHLVSTVMSGITASFRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAQSF
                     RAMSVPELTQQMFDSRNMMTACNFQNGRFLTCSALFRGKISMKEVDDQMLSIHTKNSGY
                     FVEWIPNNVQTALCSVPPKGLKMSATFVGNSTSVQELFQRVATQFTAMFRRKAFLHWYT
                     GEGMDEMEFTEAESNMNDLMSEYQQYQEASISDGEEQPYAEEAAYEAEE"
     PFAM_domain     join(6524..6529,6606..6629,6694..6719,6775..6816,
                     6866..7376,7426..7443)
                     /aSDomain="Tubulin"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00091.28"
                     /db_xref="GO:0005525"
                     /description="Tubulin/FtsZ family, GTPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00250_0020"
                     /evalue="5.30E-68"
                     /gene_ontologies="GO:0005525: GTP binding"
                     /label="AFUA_7G00250"
                     /locus_tag="AFUA_7G00250"
                     /protein_end="211"
                     /protein_start="2"
                     /score="229.2"
                     /tool="antismash"
                     /translation="EIVHLQTGQCGNQVGAAFWQTISSEHGLDESGLCNASSDQQLERM
                     NVYFNEVGNSKYVPRAVLVDLEPGTMDAIRSGPHGALFRPDNFVFGQSSAGNNWAKGHY
                     TEGAELVDQVIDVVRREAESCDYLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMA
                     TFSVLPSPKVSDTVVEPYNATLSVHQLVEHADETFCIDNEALYDIC"
     PFAM_domain     join(7591..7760,7849..8044)
                     /aSDomain="Tubulin_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03953.20"
                     /description="Tubulin C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00250_0021"
                     /evalue="8.70E-40"
                     /label="AFUA_7G00250"
                     /locus_tag="AFUA_7G00250"
                     /protein_end="382"
                     /protein_start="260"
                     /score="135.9"
                     /tool="antismash"
                     /translation="PRLHFFMVGFAPLTSRGAQSFRAMSVPELTQQMFDSRNMMTACNF
                     QNGRFLTCSALFRGKISMKEVDDQMLSIHTKNSGYFVEWIPNNVQTALCSVPPKGLKMS
                     ATFVGNSTSVQELFQRVA"
     repeat_region   complement(7766..7803)
                     /note="microsatellite"
                     /rpt_type=tandem
                     /rpt_unit_seq="a"
     repeat_region   complement(8582..8610)
                     /note="microsatellite"
                     /rpt_type=tandem
                     /rpt_unit_seq="agacctgaaaaccg"
     CDS             complement(10001..12070)
                     /EC_number="5.4.99.17"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_7G00260"
                     /note="encoded by transcript AFUA_7G00260A; similar to
                     GB:BAC91998.1: squalene-hopene cyclase [Gloeobacter
                     violaceus]; GO_component: GO:0005783 - endoplasmic
                     reticulum; GO_component: GO:0005811 - lipid particle;
                     GO_component: GO:0005886 - plasma membrane; GO_function:
                     GO:0000250 - lanosterol synthase activity; GO_function:
                     GO:0051007 - squalene-hopene cyclase activity; GO_process:
                     GO:0006696 - ergosterol biosynthetic process; GO_process:
                     GO:0019746 - hopanoid biosynthetic process"
                     /old_locus_tag="Afu7g00260"
                     /product="squalene-hopene-cyclase, putative"
                     /protein_id="EAL84865.1"
                     /sec_met_domain="terpene_cyclase (E-value: 1.4e-25,
                     bitscore: 85.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLQTEAITTEGLRVRSLSPDDPLLPRIKQAIKLSGQHSRGEMHSD
                     GHWCGEVKTNATTSAEHVLLCQALGINLDADREAFISWFRCTQGADGGWSTAPDQAGDI
                     SVTVEAYLALKILGLSEDDAAMRRARDFAIAAGGVAKVRIFTRIYLALFGLFPWAAVPE
                     LPPELILLPSRVPVSIYHWSAWARATVVPLLIISHHRPIYALPGGGKGTSSDYLDELWC
                     DPQNKMIPYNHDEPTAWRSDPFASIFTLADSILHRLDGLRSFNPFRRFALQKCVDWILE
                     HQEDMGDIGDIMPPLHGAMLALRLEGYPLHSGPIHRGLEAIERFAYRDKQGKRIQTTVS
                     AFWDTSLMLIALGDAGMASKPWLTRSLGWLQQHQRLGNYGDWKVNNHGLKAGGFSFGYF
                     NTWYPDVDDTASAVLAMIRQDERLVHSASVLDALNWLLGMQNTDGGWGAFDRDNDKHFL
                     NKIPFSDMDALCDPSTPDVTGHVLEAFGLFLALSKADALADRVVAASRRAIRYLSDTHV
                     LSRGWYGRWGCNYIYGTSAVLCALAYFGSENDALSGVRVMKDAINQAIRWLETVQNPDG
                     GWGETVDSYKDPSRAGSGPSTASQTAWAIMALLPYLPPSTEVIQRGMEYLLRTQTKTAS
                     QGATWHEKAYTATGFPKYFYMGYSLYAHYFPMMALGRYAYPCPAWHENWRLKRD"
     subregion       <10001..>25956
                     /aStool="cassis"
                     /abundance=119
                     /abundance_left=55
                     /abundance_right=64
                     /contig_edge="False"
                     /gene_left="AFUA_7G00260"
                     /gene_right="AFUA_7G00300"
                     /genes=5
                     /label="AFUA_7G00300"
                     /motif_left="+06_-13"
                     /motif_right="+00_-13"
                     /motif_score="6.0e-01"
                     /motif_score_left="6.0e-01"
                     /motif_score_right="2.2e-03"
                     /note="best prediction (most abundant) for anchor gene
                     AFUA_7G00300"
                     /promoter_left="AFUA_7G00260+AFUA_7G00270"
                     /promoter_right="AFUA_7G00300"
                     /promoters=3
                     /subregion_number="1"
     subregion       <10001..>25956
                     /aStool="cassis"
                     /abundance=67
                     /abundance_left=43
                     /abundance_right=24
                     /contig_edge="False"
                     /gene_left="AFUA_7G00260"
                     /gene_right="AFUA_7G00300"
                     /genes=5
                     /label="AFUA_7G00260"
                     /motif_left="+08_-11"
                     /motif_right="+09_-11"
                     /motif_score="1.4e+00"
                     /motif_score_left="6.0e-01"
                     /motif_score_right="7.8e-01"
                     /note="best prediction (most abundant) for anchor gene
                     AFUA_7G00260"
                     /promoter_left="AFUA_7G00260+AFUA_7G00270"
                     /promoter_right="AFUA_7G00300"
                     /promoters=3
                     /subregion_number="2"
     gene            complement(<10001..>12070)
                     /locus_tag="AFUA_7G00260"
                     /old_locus_tag="Afu7g00260"
     mRNA            complement(<10001..>12070)
                     /locus_tag="AFUA_7G00260"
                     /note="transcript AFUA_7G00260A"
                     /old_locus_tag="Afu7g00260"
                     /product="squalene-hopene-cyclase, putative"
     PFAM_domain     complement(10049..11056)
                     /aSDomain="SQHop_cyclase_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13243.9"
                     /description="Squalene-hopene cyclase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00260_0023"
                     /evalue="1.60E-106"
                     /label="AFUA_7G00260"
                     /locus_tag="AFUA_7G00260"
                     /protein_end="674"
                     /protein_start="338"
                     /score="356.1"
                     /tool="antismash"
                     /translation="VSAFWDTSLMLIALGDAGMASKPWLTRSLGWLQQHQRLGNYGDWK
                     VNNHGLKAGGFSFGYFNTWYPDVDDTASAVLAMIRQDERLVHSASVLDALNWLLGMQNT
                     DGGWGAFDRDNDKHFLNKIPFSDMDALCDPSTPDVTGHVLEAFGLFLALSKADALADRV
                     VAASRRAIRYLSDTHVLSRGWYGRWGCNYIYGTSAVLCALAYFGSENDALSGVRVMKDA
                     INQAIRWLETVQNPDGGWGETVDSYKDPSRAGSGPSTASQTAWAIMALLPYLPPSTEVI
                     QRGMEYLLRTQTKTASQGATWHEKAYTATGFPKYFYMGYSLYAHYFPMMALGRYA"
     aSDomain        complement(10049..11944)
                     /aSDomain="TIGR01787"
                     /aSTool="tigrfam"
                     /description="squalene_cyclas: squalene/oxidosqualene
                     cyclases"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_7G00260_0004"
                     /evalue="8.40E-152"
                     /identifier="TIGR01787"
                     /label="AFUA_7G00260"
                     /locus_tag="AFUA_7G00260"
                     /protein_end="674"
                     /protein_start="42"
                     /score="504.9"
                     /tool="antismash"
                     /translation="HSDGHWCGEVKTNATTSAEHVLLCQALGINLDADREAFISWFRCT
                     QGADGGWSTAPDQAGDISVTVEAYLALKILGLSEDDAAMRRARDFAIAAGGVAKVRIFT
                     RIYLALFGLFPWAAVPELPPELILLPSRVPVSIYHWSAWARATVVPLLIISHHRPIYAL
                     PGGGKGTSSDYLDELWCDPQNKMIPYNHDEPTAWRSDPFASIFTLADSILHRLDGLRSF
                     NPFRRFALQKCVDWILEHQEDMGDIGDIMPPLHGAMLALRLEGYPLHSGPIHRGLEAIE
                     RFAYRDKQGKRIQTTVSAFWDTSLMLIALGDAGMASKPWLTRSLGWLQQHQRLGNYGDW
                     KVNNHGLKAGGFSFGYFNTWYPDVDDTASAVLAMIRQDERLVHSASVLDALNWLLGMQN
                     TDGGWGAFDRDNDKHFLNKIPFSDMDALCDPSTPDVTGHVLEAFGLFLALSKADALADR
                     VVAASRRAIRYLSDTHVLSRGWYGRWGCNYIYGTSAVLCALAYFGSENDALSGVRVMKD
                     AINQAIRWLETVQNPDGGWGETVDSYKDPSRAGSGPSTASQTAWAIMALLPYLPPSTEV
                     IQRGMEYLLRTQTKTASQGATWHEKAYTATGFPKYFYMGYSLYAHYFPMMALGRYA"
     aSDomain        complement(10049..12010)
                     /aSDomain="TIGR01507"
                     /aSTool="tigrfam"
                     /description="hopene_cyclase: squalene-hopene cyclase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_7G00260_0003"
                     /evalue="5.90E-177"
                     /identifier="TIGR01507"
                     /label="AFUA_7G00260"
                     /locus_tag="AFUA_7G00260"
                     /protein_end="674"
                     /protein_start="20"
                     /score="587.8"
                     /tool="antismash"
                     /translation="DPLLPRIKQAIKLSGQHSRGEMHSDGHWCGEVKTNATTSAEHVLL
                     CQALGINLDADREAFISWFRCTQGADGGWSTAPDQAGDISVTVEAYLALKILGLSEDDA
                     AMRRARDFAIAAGGVAKVRIFTRIYLALFGLFPWAAVPELPPELILLPSRVPVSIYHWS
                     AWARATVVPLLIISHHRPIYALPGGGKGTSSDYLDELWCDPQNKMIPYNHDEPTAWRSD
                     PFASIFTLADSILHRLDGLRSFNPFRRFALQKCVDWILEHQEDMGDIGDIMPPLHGAML
                     ALRLEGYPLHSGPIHRGLEAIERFAYRDKQGKRIQTTVSAFWDTSLMLIALGDAGMASK
                     PWLTRSLGWLQQHQRLGNYGDWKVNNHGLKAGGFSFGYFNTWYPDVDDTASAVLAMIRQ
                     DERLVHSASVLDALNWLLGMQNTDGGWGAFDRDNDKHFLNKIPFSDMDALCDPSTPDVT
                     GHVLEAFGLFLALSKADALADRVVAASRRAIRYLSDTHVLSRGWYGRWGCNYIYGTSAV
                     LCALAYFGSENDALSGVRVMKDAINQAIRWLETVQNPDGGWGETVDSYKDPSRAGSGPS
                     TASQTAWAIMALLPYLPPSTEVIQRGMEYLLRTQTKTASQGATWHEKAYTATGFPKYFY
                     MGYSLYAHYFPMMALGRYA"
     PFAM_domain     complement(11081..11971)
                     /aSDomain="SQHop_cyclase_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13249.9"
                     /description="Squalene-hopene cyclase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00260_0022"
                     /evalue="2.20E-95"
                     /label="AFUA_7G00260"
                     /locus_tag="AFUA_7G00260"
                     /protein_end="330"
                     /protein_start="33"
                     /score="319.3"
                     /tool="antismash"
                     /translation="SGQHSRGEMHSDGHWCGEVKTNATTSAEHVLLCQALGINLDADRE
                     AFISWFRCTQGADGGWSTAPDQAGDISVTVEAYLALKILGLSEDDAAMRRARDFAIAAG
                     GVAKVRIFTRIYLALFGLFPWAAVPELPPELILLPSRVPVSIYHWSAWARATVVPLLII
                     SHHRPIYALPGGGKGTSSDYLDELWCDPQNKMIPYNHDEPTAWRSDPFASIFTLADSIL
                     HRLDGLRSFNPFRRFALQKCVDWILEHQEDMGDIGDIMPPLHGAMLALRLEGYPLHSGP
                     IHRGLEAIERFAYRDK"
     promoter        12020..13472
                     /locus_tag="AFUA_7G00260"
                     /locus_tag="AFUA_7G00270"
                     /note="bidirectional promoter"
                     /seq="AAGCTGCGAACTCGTAGCCCTTCTGTTGTGATGGCCTCTGTCTGCAACATCGC
                     GAGGGTCAATTGGCATCGAGGAAGAGAATTGACCAAGCTGACGACAGTCCGCGTTCTAT
                     GTCGAGACGGGATGGTCCACTACATATGCTACTTGAGCGGTAACAGCTAACCCATAGCG
                     ACTTCTTGCGGTGCTGTGATCAATGGATGGACCATAACTGTGGACCTGACGAATCCGGC
                     ATGGGAGCGAAAAGTTAAAAGCCTTAAGCTCTATTAGTATCGCGCCCTTGGACCTGGTC
                     ATTATAGATGGTGCCATAGCTTTTCCGGATGCTGGACAACTTGTCGACTCGTCATCCGT
                     CTCGGTCAGGGTCCAGACATGGAGTATACTTGCAAGATCCATGCTAAATTGCTTCAATT
                     GTAGCAGTAATGATGAGTGACGCAGACTCCCTTTACGTGGGGCTCGCTACCAGACCTCT
                     CTGAGGTTGCAAGTCCTGCCATTACAGAGGTGATGAAGATATCATTCTCTTGACTGGCC
                     GGGTGGAAGCATCCGGGTAAGGGACCCGCGGAACCAACAGATGGGTCACATCCTTCTAG
                     GGCAGTGGGACAGTGGCGCGTATGACAGCGGTCTAGAACTTACTCAAAGGTAGGGCAAA
                     GAGCCAGAATCACTTCGAGTCCAGTGTTCATGGGTTCTACCATGGGTCCGGGCATCTGA
                     CAGCTGCCGATGTAACCATGTCGCATTCCACAAGCTTGAGGATCTTCACGGTGTAATCA
                     ACATAGGTCTCTAATTAGTGTTTAATAGCTCAGTAATGACTGTATATCTCTAATCCGTT
                     CAGATATACAGGCCATCTCGAAGACAGTCATTGTCCTGCTATTGCGCTGCCGGATTGGG
                     ACGAGTTGCAGCGGGCCGCGGGATACGGGTGATCCCAGGACAGGTTTGGATCGCTCAGA
                     ACGGCTGAGTACAAAGCTATTGTGGGTCATCTGGCCAGTGAGACATCATTCTTCTGTAG
                     TGAGGCGATTGCACCACTGCAATCATATGTTTTGCGGAGATATCCATGACAGTCACTAC
                     GGGGCCAGTCCAGCCTCAATTCCCAGGCGAGAACAGCACTGACGACTCAAACCGCAACA
                     TCTGGTGTTGTTTCTCCCAAGTTAGACGCGCCAACATGTATAAATCCCGAGTCCTCGGG
                     CTCGAGTCTCAGAATGGCCCCCTTTGGTAATTAACGTCATTATTGCGCATGCAAATCGA
                     CTGAGGCAAGGTCCACTTTATACTGTGTACAAAGTTGCTATACGAAGTTGGTTCGGCTT
                     GTCTTTTTCAAAGACTATTCGTTAACTGTTTGTTTTTCGAAGCTTTCCATGAGATCTCA
                     TGGGAATATCTGTCCCGATAAACCCATACTAGCCCCATCGGACTCCCGAGAATGGATCC
                     CCCTTTCAAGGTCATAATTGTCGGGGGATCAATTGCCGGCCTT"
                     /tool="antismash"
     gene            <13423..>15065
                     /locus_tag="AFUA_7G00270"
                     /old_locus_tag="Afu7g00270"
     mRNA            join(<13423..13712,13780..14051,14116..14486,14550..>15065)
                     /locus_tag="AFUA_7G00270"
                     /note="transcript AFUA_7G00270A"
                     /old_locus_tag="Afu7g00270"
                     /product="FAD binding monooxygenase, putative"
     CDS             join(13423..13712,13780..14051,14116..14486,14550..15065)
                     /EC_number="1.14.13.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 258.8; E-value: 1.6e-78)"
                     /gene_kind="other"
                     /locus_tag="AFUA_7G00270"
                     /note="encoded by transcript AFUA_7G00270A; GO_function:
                     GO:0004497 - monooxygenase activity; GO_process: GO:0006725
                     - aromatic compound metabolic process"
                     /old_locus_tag="Afu7g00270"
                     /product="FAD binding monooxygenase, putative"
                     /protein_id="EAL84864.1"
                     /transl_table=1
                     /translation="MDPPFKVIIVGGSIAGLTLAHCLHRAEIPCIVLEKRPQIAPQEGA
                     SVAILPNGARILEQLEVYDAVEKLVKPKHVLNMYFPDGFHFSDPYPKTMNELFGFPMAC
                     LDRQQLLQVLYQLFPKKPDIYVGKSVVGVDEQDSRVLVYTADGSTYEGDLVVGADGVHS
                     RVRTQMWRAAKMRRPGLISESEMKGMSIEYACIFGASPTVPGLDERHLHSRVDNGTAFI
                     LVPGVNGRLSWFIIVRLDKKYQYGSAPRFSVKDAAAWGERLTDKNIWKDIKFEQVWQSR
                     QTVDMTALEETIFRNWSCGRIVCIGDSMHKMTPNLGQGANCAIEDAAALTNKLHDALKV
                     KNPGRKLSDDEIEQALSEFSNIQVKRISKIYNVSWTTARLQTRANLVYRLLLRYFIPYA
                     GDKPAKRVLRIFEGATALDFIPLPTRSGPGWTPQKREETFFPRWTIALAFLVLISVVSI
                     NLKPVGYYSYWLSLLGGFLMDRIR"
     PFAM_domain     join(13438..13712,13780..14051,14116..14486,14550..14633)
                     /aSDomain="FAD_binding_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01494.22"
                     /db_xref="GO:0071949"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00270_0024"
                     /evalue="1.60E-25"
                     /gene_ontologies="GO:0071949: FAD binding"
                     /label="AFUA_7G00270"
                     /locus_tag="AFUA_7G00270"
                     /protein_end="339"
                     /protein_start="5"
                     /score="90.2"
                     /tool="antismash"
                     /translation="KVIIVGGSIAGLTLAHCLHRAEIPCIVLEKRPQIAPQEGASVAIL
                     PNGARILEQLEVYDAVEKLVKPKHVLNMYFPDGFHFSDPYPKTMNELFGFPMACLDRQQ
                     LLQVLYQLFPKKPDIYVGKSVVGVDEQDSRVLVYTADGSTYEGDLVVGADGVHSRVRTQ
                     MWRAAKMRRPGLISESEMKGMSIEYACIFGASPTVPGLDERHLHSRVDNGTAFILVPGV
                     NGRLSWFIIVRLDKKYQYGSAPRFSVKDAAAWGERLTDKNIWKDIKFEQVWQSRQTVDM
                     TALEETIFRNWSCGRIVCIGDSMHKMTPNLGQGANCAIEDAAALTNKLHDALK"
     gene            complement(<16789..>18419)
                     /locus_tag="AFUA_7G00280"
                     /old_locus_tag="Afu7g00280"
     mRNA            complement(join(<16789..16905,16986..17214,17272..17407,
                     17461..17744,17776..18098,18222..>18419))
                     /locus_tag="AFUA_7G00280"
                     /note="transcript AFUA_7G00280A"
                     /old_locus_tag="Afu7g00280"
                     /product="conserved hypothetical protein"
     CDS             complement(join(16789..16905,16986..17214,17272..17407,
                     17461..17744,17776..18098,18222..18419))
                     /codon_start=1
                     /locus_tag="AFUA_7G00280"
                     /note="encoded by transcript AFUA_7G00280A; GO_component:
                     GO:0030136 - clathrin-coated vesicle; GO_component:
                     GO:0030137 - COPI-coated vesicle; GO_function: GO:0005554 -
                     molecular function unknown; GO_process: GO:0000004 -
                     biological process unknown"
                     /old_locus_tag="Afu7g00280"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL84863.1"
                     /transl_table=1
                     /translation="MSTTTVELAPPGQQESQRSVHTFGPTGDDAIVQAKQKWNDPPINK
                     WRVLATFASFAVVGASDGVYGLREDYKLSTTVVSLIFVTPFAGYAIATLVVNKIHMTLG
                     QRGIAIIGPLCHIAPFVIMAIHPPWPVMLAVYVIVGLGNGLIDAAWNSWVADMANANTM
                     TGLLGAFYGVGNTDGRPRATLSPTIATQMIKSGLHWNYFYYTLLGGSVLELLTSVATFW
                     QENAVSYRAKNRRSPDSSGGSRTTEAMKSPITWLIASWLFVYMGVEVSVGGWVVDFMIQ
                     ERNGKPFESGLVPTGFWAGVTVGRLVLGFVNDWRADCHHYIPCYFNCPGTCLLAGPKVC
                     RLCRCCLDARFLYRPSLSCGSCSGGQAASEASAYPGHWARVIIGRRWCRNTALCCWCDI
                     RGARCAKPATVHSLIVGPHDHYLGATSSE"
     PFAM_domain     complement(join(17214,17272..17407,17461..17744,
                     17776..18098,18222..18275))
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF07690.19"
                     /db_xref="GO:0022857"
                     /db_xref="GO:0055085"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00280_0025"
                     /evalue="2.20E-14"
                     /gene_ontologies="GO:0022857: transmembrane transporter
                     activity"
                     /gene_ontologies="GO:0055085: transmembrane transport"
                     /label="AFUA_7G00280"
                     /locus_tag="AFUA_7G00280"
                     /protein_end="314"
                     /protein_start="48"
                     /score="53.3"
                     /tool="antismash"
                     /translation="LATFASFAVVGASDGVYGLREDYKLSTTVVSLIFVTPFAGYAIAT
                     LVVNKIHMTLGQRGIAIIGPLCHIAPFVIMAIHPPWPVMLAVYVIVGLGNGLIDAAWNS
                     WVADMANANTMTGLLGAFYGVGNTDGRPRATLSPTIATQMIKSGLHWNYFYYTLLGGSV
                     LELLTSVATFWQENAVSYRAKNRRSPDSSGGSRTTEAMKSPITWLIASWLFVYMGVEVS
                     VGGWVVDFMIQERNGKPFESGLVPTGFWAGVTVGRLVLGFVNDW"
     promoter        18369..19919
                     /locus_tag="AFUA_7G00280"
                     /locus_tag="AFUA_7G00290"
                     /note="bidirectional promoter"
                     /seq="TGTGACTCTTGTTGTCCTGGTGGCGCAAGCTCAACCGTTGTCGTCGACATATT
                     CGCTGTTCCAGAAGAGAGAAATATGATGAGACACAAGGAGCCAGATGGCGACGAGAAGA
                     TTACGAGATATTAGTGCTGCCACGAGTCAATAAATACTGCCTTGAGCATCTTTCCCCAC
                     TTGATGAGTCAAGAACTTGTTCTTTCTTCTTGGAAGCTGACCCACTGAGGCAGAACCAG
                     AACACATCTATGGACAGCCAAGTCTTTAGCCTCTAGACTATGGATGTGGGTAGAAAGGT
                     GTTTCACTGCCCTTTCTGACACCCAAGCCACAGTGCCTTTTAACGCCTTCTGGAAGTTG
                     GCAGCTGCATCTACCCACGTTTCTGGAGTGTGGAATTTGGAGGATCAATAAGGACATTG
                     ATTGAACACACTGAAGGCACAGCTGACTTAGCAGGTATTTTTAAGGCTTCCTTGTGCAT
                     TCGGCAGTGGAACTGTCGCCTAAATCTCCGATCCCTGTCGTGCTACCCTTTGTCTGTGC
                     CTTCAGTGCGAGCTCAGAGGTTCACTATGCCGAATTACTGAACCGTAAATTTATTGGCC
                     AAAGCGATCGGCTCCTTTGGCCGGATTCAAGCCTAAGTCCTGATCATACACTTGGTCAG
                     CAGAATCAAACCATAGGTCTAATAGCAAAACTGTATATTGACCAAGATTGCACCTGCGC
                     GCCACCACTAGTGACACCAAGATAGATGACGTATACCATACTCGGGAGCCAAGTCAAGC
                     AATAGCAACACAGAGCGAACAGTGATTGTGATAGACTCAAGACGCACAAGTAGTTTAAT
                     TAGCTGGAAGGCTACCCTTTACATGCATCCCATGAGTTTCGGCTGTGTAATGGATTCTC
                     GCACTTGGAGGGGAGGTGATTTGCTCATGCCACACGGCCTGATATCCGGGTGCTCTCAA
                     TAATTCTGCAAATCTTAAACTGGCTAGGAGTGCTCATTAGCACATATGCTGGAGAGGCG
                     GCACCGGGGAAGAGACCTGGAAATTGCGAGATCGGGTTGTTTGCAGTCCGGTCTATTAT
                     GCCATCCTAAGTATCCATGTAATACTTTGAAGGGCGCTGGATTATGACGCAACAACGGT
                     ATCAGCTGCACCACCCTCAACTTTTTGATACATGATATAGAATCCTCGAATCTTGCTGT
                     TTGCTTGGGATAAGCGTTGAGTTTCAAAATTCTCGCCGAGCACTGATTAAAGATAAATA
                     TGCATGAGTTATATGGGTACCTGTGTGGAAGGGGAGGAATTACCGTGGGCATTTCCCTG
                     GTACAAACTGCAATTTCCTCATTTCTGGCTGTTGATGGGTGTAGGTTCTGACAAGGGAT
                     AGGTGGTCTGCTATGTAATCACCCAAGCCGTCTATAACGTGTTCCTCCATCCCTTAAGT
                     CGCTTCCCCGGCCCACTATTGCACAGGGCGTCGCGGCTGGCATATGTCTATCGGTTGAT
                     CGGAGGGACGCTTACCTTGGACGCACTCGAAATGCATCAACGCTACGGAGATATTGTAC
                     GAGTCGCCCCTGATGAGCTCTTT"
                     /tool="antismash"
     gene            <19870..>21341
                     /locus_tag="AFUA_7G00290"
                     /old_locus_tag="Afu7g00290"
     mRNA            join(<19870..20505,20575..20889,20948..21114,21164..>21341)
                     /locus_tag="AFUA_7G00290"
                     /note="transcript AFUA_7G00290A"
                     /old_locus_tag="Afu7g00290"
                     /product="cytochrome P450 monooxygenase, putative"
     CDS             join(19870..20505,20575..20889,20948..21114,21164..21341)
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 350; E-value: 3.7e-106)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_7G00290"
                     /note="encoded by transcript AFUA_7G00290A; similar to
                     SP:O13317: Isotrichodermin C-15 hydroxylase (EC 1.14.-.-)
                     (Cytochrome P450 65A1). {Fusarium sporotrichioides];
                     GO_function: GO:0016491 - oxidoreductase activity;
                     GO_process: GO:0008152 - metabolic process"
                     /old_locus_tag="Afu7g00290"
                     /product="cytochrome P450 monooxygenase, putative"
                     /protein_id="EAL84862.1"
                     /sec_met_domain="p450 (E-value: 5.7e-71, bitscore: 234.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MHQRYGDIVRVAPDELFFAHPDAWSDIHKKTGREMDKAPWFYRPL
                     EQSPRCIVDESHEQHSRLRRQMAPGFSEKSMRDQEPIIRGYVDLLLQRLLEKSNDGQPV
                     VISDWFNYTTFDIIGDLVFGEPFECLGSSKYDGWIKSIFESLRPLTIVQALSFFPWLKR
                     IALDTVPKNLQGDIKQQQQQTEAKMRRRMAVTASRGDLMEGLLKKKDELHLSTEELIGN
                     AQVLILAGSETTASLLSGVIYLLLQNAVAYRQLVDEVRSTFNSEKDINFVSVSQLSYML
                     ACLNEALRIYPPVANGLPRVVPKGGAQILGQYIPEQTYVAIPQWALYHREQYFAEPNDF
                     HPERFLGDPKFANDRRDALQPFSVGPRNCLGRNLAYAEMRLILALVIFHFDMKIDPDCR
                     DWIQQRNFTLWQKPPLKVYLKPVARKSEPNQV"
     PFAM_domain     join(19873..20505,20575..20889,20948..21114,21164..21290)
                     /ASF="active site cysteine inconclusive"
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00290_0026"
                     /evalue="1.70E-69"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_7G00290"
                     /locus_tag="AFUA_7G00290"
                     /protein_end="415"
                     /protein_start="1"
                     /score="234.9"
                     /tool="antismash"
                     /translation="HQRYGDIVRVAPDELFFAHPDAWSDIHKKTGREMDKAPWFYRPLE
                     QSPRCIVDESHEQHSRLRRQMAPGFSEKSMRDQEPIIRGYVDLLLQRLLEKSNDGQPVV
                     ISDWFNYTTFDIIGDLVFGEPFECLGSSKYDGWIKSIFESLRPLTIVQALSFFPWLKRI
                     ALDTVPKNLQGDIKQQQQQTEAKMRRRMAVTASRGDLMEGLLKKKDELHLSTEELIGNA
                     QVLILAGSETTASLLSGVIYLLLQNAVAYRQLVDEVRSTFNSEKDINFVSVSQLSYMLA
                     CLNEALRIYPPVANGLPRVVPKGGAQILGQYIPEQTYVAIPQWALYHREQYFAEPNDFH
                     PERFLGDPKFANDRRDALQPFSVGPRNCLGRNLAYAEMRLILALVIFHFDMKIDPDCRD
                     WIQQRNFTLWQKPPL"
     gene            complement(<22646..>25956)
                     /locus_tag="AFUA_7G00300"
     mRNA            complement(join(<22646..22867,23508..23718,23939..>25956))
                     /locus_tag="AFUA_7G00300"
                     /note="transcript AFUA_7G00300A"
                     /product="squalene-hopene-cyclase, putative"
     CDS             complement(join(22646..22867,23508..23718,23939..25956))
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_7G00300"
                     /note="encoded by transcript AFUA_7G00300A"
                     /product="squalene-hopene-cyclase, putative"
                     /protein_id="EAL84861.1"
                     /sec_met_domain="terpene_cyclase (E-value: 2.6e-18,
                     bitscore: 61.6, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLAGCCLSAFQPHIHIKMSRTVELGSQPTAMAGCPSEQQRLVSET
                     NQVLQLATQYSKVQRRPGGNWRGQTGINSIATTAEHIFMHQALGSNLDTDRDAFISWFY
                     SVQNSDGSWGISPGDRGDLSVTVEAYLALRILGVSRNVHQMRRSQSFILAEGSIANVCF
                     ITRIHLAMFGLYPWNAVRSLPPELVLLPQYILSSICCWPAVDLTVLIPLLILCHHRPIF
                     PLPIQDCAASSYLHELQCKPQEPQENAFCAFPPGTCGDTAPASTSTDLIVHLLNLLKYI
                     LPLRRYALDRSVAFILQTVREMGGVGPLSRPLHMAIVALELEGYSVSSRSLRTTLDNIG
                     HFVYEDGGGKRVLSVNTTFRDSSRMITGLQDAGIAVNAPWFRTSVQWLQRCLLPDVNSD
                     TSKTFETRVCHVDDVASAIHAVIRQDPLMLRSHLVANALQWLLKRQNADGGWTSLSSSH
                     YRTSPDKLVRQSTPDVTGHVLETFGLLLTVSRRDTRVVAQGILVDQVASASRRAIHYLS
                     ATQQPCGAWFGCCTRYHIYATSAVLRALAYFIGVKERNRWTERDDSINDDVSQAIHWLE
                     SARNRDGGWGDICWREKGGPSTASQTALALLALLPYLSPIDSILRDGVKYLLRTQTKAV
                     VGGAIWTEDQPTRACSPACTHKSSSYSSHCFVMMAIGSFRVSKGAWVRIPPLSFIFYLF
                     AHLAPTPMDLGSKSDSRMTWTVVRGLMMGPGFTSGSVAEDSSMLTTSSEADPSSAPNWA
                     TNAKCAVIQPRIVTASIERIFCWTSGACFHSLGMNLIVANTTMTLPAIQLPKTYCRIGA
                     SVGG"
     gene            complement(23673..23783)
                     /locus_tag="AFUA_7G00296"
     tRNA            complement(23673..23783)
                     /locus_tag="AFUA_7G00296"
                     /note="anticodon CAG"
                     /product="tRNA-Leu"
     PFAM_domain     complement(join(23712..23718,23939..24564))
                     /aSDomain="SQHop_cyclase_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13243.9"
                     /description="Squalene-hopene cyclase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00300_0029"
                     /evalue="4.90E-23"
                     /label="AFUA_7G00300"
                     /locus_tag="AFUA_7G00300"
                     /protein_end="675"
                     /protein_start="464"
                     /score="81.8"
                     /tool="antismash"
                     /translation="KLVRQSTPDVTGHVLETFGLLLTVSRRDTRVVAQGILVDQVASAS
                     RRAIHYLSATQQPCGAWFGCCTRYHIYATSAVLRALAYFIGVKERNRWTERDDSINDDV
                     SQAIHWLESARNRDGGWGDICWREKGGPSTASQTALALLALLPYLSPIDSILRDGVKYL
                     LRTQTKAVVGGAIWTEDQPTRACSPACTHKSSSYSSHCFVMMAIGSFR"
     PFAM_domain     complement(24604..24654)
                     /aSDomain="Prenyltrans"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00432.24"
                     /db_xref="GO:0003824"
                     /description="Prenyltransferase and squalene oxidase
                     repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00300_0028"
                     /evalue="1.80E-03"
                     /gene_ontologies="GO:0003824: catalytic activity"
                     /label="AFUA_7G00300"
                     /locus_tag="AFUA_7G00300"
                     /protein_end="451"
                     /protein_start="434"
                     /score="18.1"
                     /tool="antismash"
                     /translation="ANALQWLLKRQNADGGW"
     PFAM_domain     complement(24919..25806)
                     /aSDomain="SQHop_cyclase_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13249.9"
                     /description="Squalene-hopene cyclase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00300_0027"
                     /evalue="5.70E-60"
                     /label="AFUA_7G00300"
                     /locus_tag="AFUA_7G00300"
                     /protein_end="346"
                     /protein_start="50"
                     /score="203.0"
                     /tool="antismash"
                     /translation="LATQYSKVQRRPGGNWRGQTGINSIATTAEHIFMHQALGSNLDTD
                     RDAFISWFYSVQNSDGSWGISPGDRGDLSVTVEAYLALRILGVSRNVHQMRRSQSFILA
                     EGSIANVCFITRIHLAMFGLYPWNAVRSLPPELVLLPQYILSSICCWPAVDLTVLIPLL
                     ILCHHRPIFPLPIQDCAASSYLHELQCKPQEPQENAFCAFPPGTCGDTAPASTSTDLIV
                     HLLNLLKYILPLRRYALDRSVAFILQTVREMGGVGPLSRPLHMAIVALELEGYSVSSRS
                     LRTTLDNIGHFVYED"
     promoter        25906..26956
                     /locus_tag="AFUA_7G00300"
                     /seq="TTTATGTGGATATGTGGTTGAAAGGCCGACAAGCAGCACCCAGCAAGCATATG
                     TATATCTACACCGTCGTGCAAATACTAGACTTAGAACTTTCGCCGGCCTTGCCTGCCGC
                     CTCACTGATAACTGCATACTGGATACCAAAGGCCTGACTACGCTTACACTTTGGTCTTC
                     TCGGAGACATTGTGCCTCTAGCCTGGTTTTACAGTTCTATGATCCGTATATCAGCACAG
                     TAGACTTCAATCCCGCAGTCTCCTCCCCTCCAAACGAGCTGGTTGGATCAAGGGGGTTT
                     TCCTGGAATCCACCATGTAAAAATGTTCCACTTCCGTGGAATGGGACTGACATGGACGC
                     CGCCCCATTAACTTATCTTGATGTAGGTTTACTTCTTCCCGTCAATAAACTTTCTACGG
                     GGTCCATGTGTAGGATTTCGAATTGGCCCCTGAGGTTGATCATGCTTGATTAATCGATG
                     TCATGTCAGTTCGCCCAGGTGGCGAACGTCGTAGCAGTACCGGAAATTGACCTCGTCTT
                     GTTTCTAGAAGGGCCCATGTAGGATTGATTGTTTGCTTGACATGCAATCGGCTGCGCAA
                     GCTGAATTAGCCTCTGGTCAATTGACATCCTAGAGATGCAACTTGTTGGCAATCAAGGA
                     CGCAACTGGTAGGAGATTCCATTCGGCCCTCTACCAGTACCTTGGTCTAGATTCTTAGC
                     CGGAGCATGCAAGGGACTTTGTGTGACATACCATCCACCCCCATGCAAGAACTGGGAAA
                     GTGCTGTAAGAGGACAGGCAGTCGCATTAGTGATACCCTGGCAGAACCCGACTGTACCA
                     CGGATCCTTGACGGATACCGCAATAAACTCAGCCTGACAGTCCATGACATCTCCTTATC
                     CACACTCAAGGCAGTGCGCCCCAGTGCGGAATCGCTTTACTCTTTCCTTGCCTAGCATG
                     CCTGTGCTATGAACCATTTCTCACTTCATAGAGCGGGGGGCTTCTCAGAATGTCATCTC
                     TGGAATCTATGACCTCACAGTGATTACCTGCTGAGGTAGTCTTTTTCCTTTCTG"
                     /tool="antismash"
     gene            complement(<28329..>28676)
                     /locus_tag="AFUA_7G00310"
                     /old_locus_tag="Afu7g00310"
     mRNA            complement(<28329..>28676)
                     /locus_tag="AFUA_7G00310"
                     /note="transcript AFUA_7G00310A"
                     /old_locus_tag="Afu7g00310"
                     /product="hypothetical protein"
     CDS             complement(28329..28676)
                     /codon_start=1
                     /locus_tag="AFUA_7G00310"
                     /note="encoded by transcript AFUA_7G00310A"
                     /old_locus_tag="Afu7g00310"
                     /product="hypothetical protein"
                     /protein_id="EAL84860.1"
                     /transl_table=1
                     /translation="MDCRFRVLLVLTAAAWHFLRGWTGGNRAGVPYLTVVPTSAAISDI
                     TSSKPENRLHQRLRQEAATVPSSEEEWGAPMSFKKLHYIDSAVRETVHLTLCFRMQPTG
                     KSCIHLGLPCP"
     promoter        28626..29676
                     /locus_tag="AFUA_7G00310"
                     /seq="TGCCAAGCAGCAGCTGTAAGAACTAAGAGCACCCTAAAACGGCAGTCCATCTT
                     TGATGCCGTTAAACCAACATATCGGTCATATTCCTTAGACACGTATCCTTATACGCTTG
                     GCATAAATGCTAAGGCTGCTTTCAACCCCAGGGTTATTAGGCTGTGTCGTAAGCTTCGA
                     ACTCGGTACCATTGTTTGCGTCAAACTCGCCTCATACGGGACTGACATGAGCGAGACGA
                     TTTTCAGTCATAACAGATACCCAAGAAAATCACTCTGCAGAAGGCATGCCTCTCATGAC
                     AGTATACAGCCATTTATTTCGTGCGCAGTATGCAACAACCCATGCAAAAGCAGCAGGGT
                     ACTCCAGCCATGTGGTGTGCCAGTGGACCACAGGCACATCTGACGTTGAAGCTACTCGA
                     CCTTACATCCAAGTTGCCGTTTGGACATTGGGTGTAATGGCTATCGTTGTATTCCAATT
                     CAGCCCAATATAGATGTTGCGTAGGCGATAATCTTTCAGCGATATAATGGTGAAAACTT
                     GTTGCATGTCGCACTACTGAGCCGCACCCACGCGGCCAGCTTTGCTAGTTCCGAGGGCA
                     AAGAGCGATACATCAAGTAATCAAAGATCTCAAAAATTTGATGGAGCTCGGCTTGGATT
                     CGTTTCAAGAAGGTCACAAACAACAGTCTGCTGCGGTGGGTTCATTTCTGTCTGGGGTC
                     ATGGGTCCATCCTCCGGGTATAGGACGTCGCAGCCCCAAAGAGTAAAAGTGGCATTCTT
                     GCTCTTTTTCAGAAGAAGACAGACCAAGAGATGGCGCGAGGTTTGCAGGCTTGGTTAAC
                     TCTAAATTCACATCAGATTAGCGTGATCAGAGTTCTTGCCAATGAATCAACCTAGGACA
                     TGATATTACAGAACAGCAGTACCTAGTCTTCTACCTTCGATTCAAGTCACCCTCTTTAA
                     CAGAGAAGTTGAAAACGGCTGTTAGTTCAATCGAGATGCATGATGTGGTCTTCCGAGCT
                     TCAAAGGATCATGATATCCTCCGTTCTGAAACATGGATGGCCCCAATGTCATTT"
                     /tool="antismash"
     promoter        29971..31021
                     /locus_tag="AFUA_7G00320"
                     /seq="TGCGTACGTACTCAATAGTATACATGATACAGCCCTACCGATTTTAGTAGGGG
                     CCTGTAAGCAAGAGCAATTCCCGAATTACCGCGAATGAGAGTACCTGGACCCCAACTGT
                     GTCAACCTCCAATCCCACAATCAGGGGACAACGTCGCTGGACTCCCTGAGTTGTCCGCG
                     AGGGATCCACAAGATCCTCCAACATAAGCTTAGCAGCTCAGTGCCCTTAACTTAAGACT
                     GTTTCGACCGAAGCACAGACCAGGATGACGCGTACCACACACTATTTATGATACTGCTA
                     GAGTCGAGAACTCGCTCACCAACGGCCCGAGTCTAACTTGAATCACTGGCGCCAGCTCG
                     AGTCAGTAACGCTGCCAAATGCGTTTTGGCTTTTCTTGGCATCATTTATCAATCAGAAG
                     CAGGTGGCGCCTTTGTTGTTTCACTTGCTCCAGCCGTCCCTCCACTGCAGTCGTCAGTC
                     GTCTGTGACGACCTGGCAGCTTGTAGTGGGCAATGGCGCTGCAGGACGATCCCTGGGTC
                     TAGACGCTGGTTCATTGTGTCCTGCCTCTGTCGAGCAGAGTCTGTAGGTCGAAGCAGGT
                     GTTTGTCTCTCTTGCTCATCGTTGCGAGTGTTGCCCAAATCTTTCTCCACCTGACGATC
                     CCTCTAAGCTGACGTGTACCAGCTTGGTGGCTTCAGTGTTGAAGCAGTGTCAAAGGTGG
                     AGGAAGCATGGCACAGAGAAGGTCTCCATACTGAGCAGACTCAGTATGGACTAATGGCC
                     CTATTTGGAAATCCCTAGTCGACTGCATGCCTATATAAATGCCGTCAAATCCGCTCTCA
                     GAATCCCTATTCTTCTCCTCATAGTCCCGGTGACTCCAGAATCTAGCACACAACTTTCC
                     ATTCTTTTCAAACTTTCACACTCACACTCTTTGACTTCAAGGCCTGGTTGCCATCTTCA
                     ATCCTTCCACTTCGAATCAGATCTTCTACGTCACATAATCCGTCCATTCTATCCACTTC
                     ACAATGAAGCCTCAGACTGCTGCTTTCCTGCTCAGCCTTCTCGGCTCTACCCTG"
                     /tool="antismash"
     gene            <30972..>31898
                     /locus_tag="AFUA_7G00320"
                     /old_locus_tag="Afu7g00320"
     mRNA            <30972..>31898
                     /locus_tag="AFUA_7G00320"
                     /note="transcript AFUA_7G00320A"
                     /old_locus_tag="Afu7g00320"
                     /product="extracelular proline-glycine rich protein"
     CDS             30972..31898
                     /codon_start=1
                     /locus_tag="AFUA_7G00320"
                     /note="encoded by transcript AFUA_7G00320A"
                     /old_locus_tag="Afu7g00320"
                     /product="extracelular proline-glycine rich protein"
                     /protein_id="EAL84859.1"
                     /transl_table=1
                     /translation="MKPQTAAFLLSLLGSTLAAPIQHADKGSDVKPTPTGRGAPGGFFT
                     GFPSGVPSGLPSGFPGGPVPGGFGGDGPNGPIPSGPAPSGAPQGEEGSSSFGGQGVQAR
                     SPQDFEDSGAAPSGAIPSGAIPTGAVPSGAPNGFGGFGQGGHGGPGGPGEEGSGPSPTG
                     AVPSGAIPSGAAPSGAVGGFDGFGQASENSGNAQFQSSGTSPFGASHSGSASGHQGGRH
                     GGDYRGQHGNGSGAIPSGAAPSGAAPSGAAGGFPGFGQGGEGSGPSPTGAVPSGAAGFG
                     GQGHGQGQGSFPTGVAPSDVPSAQPTA"
     repeat_region   complement(31682..31726)
                     /note="microsatellite"
                     /rpt_type=tandem
                     /rpt_unit_seq="gcagcaccagaagga"
     gene            complement(<32411..>33633)
                     /locus_tag="AFUA_7G00330"
                     /old_locus_tag="Afu7g00330"
     mRNA            complement(join(<32411..33572,33611..>33633))
                     /locus_tag="AFUA_7G00330"
                     /note="transcript AFUA_7G00330A"
                     /old_locus_tag="Afu7g00330"
                     /product="esterase, putative"
     CDS             complement(join(32411..33572,33611..33633))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_7G00330"
                     /note="encoded by transcript AFUA_7G00330A"
                     /old_locus_tag="Afu7g00330"
                     /product="esterase, putative"
                     /protein_id="EAL84858.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.4e-08, bitscore:
                     28.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MRVFCIPMLWDLHANNSSIDQCEGLVAFEYTNGLVRKPNTLVFIG
                     GLGDGLGTVEYLTDIITALEYTPWSVFSPILSSSYSGWGVGHLGKDIDEIARCVQYARE
                     YKQGLFGAGKIVIMGHSTGSQDVMHYLSCANPRPRHPVLDKDAAVEPPKRPPVDGAVMQ
                     APVSDREAITWVIRDGTDRDGPGRMREIYQRTIARARSTPYEDDDTLDTILPLSATTRI
                     GYPSSTPVSSRRFLSLASPDSPEKPEEDDLFSSDLTDDQMQKTFGQLGSRGLLGSKLLV
                     LYSGRDQSVPPWVDKEHLLKRWSLAAGDRWDSNSMIIPNASHALSDEDQAEPRRILVER
                     VMSYLENVEKHPTNCELISSTKSDQARSIEPDSCDQTGGLLCGRLPLSMPSEQV"
     PFAM_domain     complement(32561..33529)
                     /aSDomain="DUF1749"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08538.13"
                     /description="Protein of unknown function (DUF1749)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00330_0030"
                     /evalue="1.00E-97"
                     /label="AFUA_7G00330"
                     /locus_tag="AFUA_7G00330"
                     /protein_end="345"
                     /protein_start="22"
                     /score="327.0"
                     /tool="antismash"
                     /translation="EGLVAFEYTNGLVRKPNTLVFIGGLGDGLGTVEYLTDIITALEYT
                     PWSVFSPILSSSYSGWGVGHLGKDIDEIARCVQYAREYKQGLFGAGKIVIMGHSTGSQD
                     VMHYLSCANPRPRHPVLDKDAAVEPPKRPPVDGAVMQAPVSDREAITWVIRDGTDRDGP
                     GRMREIYQRTIARARSTPYEDDDTLDTILPLSATTRIGYPSSTPVSSRRFLSLASPDSP
                     EKPEEDDLFSSDLTDDQMQKTFGQLGSRGLLGSKLLVLYSGRDQSVPPWVDKEHLLKRW
                     SLAAGDRWDSNSMIIPNASHALSDEDQAEPRRILVERVMSYL"
     promoter        33583..34187
                     /locus_tag="AFUA_7G00330"
                     /seq="AGCCCGCGCGTCTTACGGAGTACATACATAGGGATGCAGAATACCCGCATGGC
                     CCTTGGTTCGTGGTTGCCGCAAAGGAAGCTGCATTTTGCGGTCGCAAATCAGCAGAACT
                     GGCACAACCGTACCGGTTATATTTGCTGTATGCTTTGCTGAATCAAGAGAGATGACACT
                     GGGAGTGATGAAGAGAACAGGAGTTGTTTGGCGTCTTGACAGAGGAAGGGAGAAAGGGA
                     AGATTCGTTGGAGACAGCTTCACCAGCCCTACCGGGAAAACCTCGGCCCGCAGCAGCTG
                     TGGTAGACTGAATTAGGACGAATCATTCAAATACCATGGTATACTGATCCAACTGTATA
                     CCATGTACGTATAAATAGAAGCCAGATGTGCCTGTGTCATTACATGCTACAGATGTCTG
                     ATCTACAATTTGCCCTCTCGTTTCGGTTCTGTCAGGATCTGATAAGATTAGATGCAGTA
                     GGATCTACAGAGTACAAAGCACTTGGCCTAACCCAATCGGGCGTTCCGTGCCGGCCGCA
                     GAGGAATTAGACTACTATAATTACTTTTGGTATATGTACAAAATACCGGTATCTTGCTG
                     CTTCATCTGACTGTGACAACA"
                     /tool="antismash"
     gene            complement(<34189..>35140)
                     /locus_tag="AFUA_7G00340"
                     /old_locus_tag="Afu7g00340"
     mRNA            complement(join(<34189..34598,34654..>35140))
                     /locus_tag="AFUA_7G00340"
                     /note="transcript AFUA_7G00340A"
                     /old_locus_tag="Afu7g00340"
                     /product="metallo-beta-lactamase domain protein, putative"
     CDS             complement(join(34189..34598,34654..35140))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     151.7; E-value: 2.9e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_7G00340"
                     /note="encoded by transcript AFUA_7G00340A; GO_function:
                     GO:0003824 - catalytic activity; GO_process: GO:0008152 -
                     metabolic process"
                     /old_locus_tag="Afu7g00340"
                     /product="metallo-beta-lactamase domain protein, putative"
                     /protein_id="EAL84857.1"
                     /transl_table=1
                     /translation="MEPGEPTIHDVFESKTGTWQYVVADPTTSTAVIIDPVLDYDPATQ
                     GITTESADALLSLVKEKGYKVDRILETHAHADHLTAASYLQKRLAEEQGHRPRIGIGKR
                     IGQVQKLFGQRYGIPEQEYKDVFDKLFEDDETFKIGNLMAQAIHLPGHTPDHLGYRIGD
                     NVFCGDLIFHSDIGTARCDFPGGSANNLYRSGRKVLGLPDHVKVWTGHDYPPEGRKEPV
                     PSLSVHEHRQQNKHLRDGVTEEEFVTLRKERDSKLAEPRLLHQSLQMNIRAGRLPKPTE
                     SGQRLLHLPLKLKGLKW"
     PFAM_domain     complement(join(34453..34598,34654..35089))
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00753.30"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_7G00340_0031"
                     /evalue="1.60E-20"
                     /label="AFUA_7G00340"
                     /locus_tag="AFUA_7G00340"
                     /protein_end="211"
                     /protein_start="17"
                     /score="74.1"
                     /tool="antismash"
                     /translation="TWQYVVADPTTSTAVIIDPVLDYDPATQGITTESADALLSLVKEK
                     GYKVDRILETHAHADHLTAASYLQKRLAEEQGHRPRIGIGKRIGQVQKLFGQRYGIPEQ
                     EYKDVFDKLFEDDETFKIGNLMAQAIHLPGHTPDHLGYRIGDNVFCGDLIFHSDIGTAR
                     CDFPGGSANNLYRSGRKVLGLPDHVKVWTGH"
     promoter        35090..35881
                     /locus_tag="AFUA_7G00340"
                     /locus_tag="AFUA_7G00350"
                     /note="bidirectional promoter"
                     /seq="CCTGTCTTGCTCTCAAACACATCGTGAATGGTCGGTTCTCCTGGTTCCATGGT
                     TGCAGTGCTATACGTTACTCGATGAACGGGCCCATTCAGGGAGCTTTTGCTAGGATAGG
                     CGCGATTATTCAGAGCACGGACTTTTGACAGCGGTCTTGTATAGACTGCTAACGGTCTC
                     AGATGCACTTTTCCAGTCGTGTAGGGCGACTTCTGTGTAGCTCTATAAGGAAGAGGGCG
                     CAGTGGCACTCGGACTGCAGTAGGAGGCGCCCCGAACAGACCCGCTGTTACTTGCCAAT
                     TTCTGCAGATGTGAGGTTGAATCGATGCCATGTTCAAATATGTCTGCGCTCAATAGCAG
                     TGCCAAAGACACATGCGATCTGCAGCTGTTTATACATCCCTCGGTCTCTATGCAGCCAA
                     TGCATCGGGGATCGACCTGTACTCACTCGGCGATCCAAGCACATGACTTTGAATCGGCG
                     ACTGGCTTCTATGCATGACATCACTATTTATGCAGCTGACATAATAAATGCCAAGCATA
                     ACGAACTTAAACGTGGTCGCCGATACAGGGGCGGGTGGGCCCACCGGGCTTATCAGAAT
                     TTCTTATCGCACCATTCATAATCGCTCCTGATTGCGACATCCGGGGCCCTTTTTATCGG
                     TCGTATTTCTGTAATCATCGTGCCGTTCAACTCTTGCTTCCTTTTGTTCACTTGCACTC
                     CAGTTCTCTTACATCTTCCGGTCTCATATCATGTCAGTCATGTTTCGCAGCCGCGTAAC
                     AGTGGCAGCCTCTGCTGCTGTTTCTCACTCG"
                     /tool="antismash"
ORIGIN
        1 agaaatgcaa ttgttaatgc cacaccgcta aaagttgtga atagtgaact tttgattaca
       61 ttcgagatac tgtctatact ctaatgtggt ttaaaacagt ctaatgcatc cttccaatcc
      121 gggatcaggc cactcactga tgtctcaggt caggattctg ctctgctttc taacttctcg
      181 acgtaaacag atcgtggtat cggtacaggg cgtgcagttt ctaggacgaa cctaggtctg
      241 cgttttcctc atagcttgat ttggtacttt ggatgggtcc tcaaccgttc tccatacttc
      301 aaggacatga aaatcatgcc catcataagc aaggatatac cggccagaag cgtatttccc
      361 cagccctgac caaggctact atacattcga ggacccgcaa ggggaagaaa cgcgcccccc
      421 acactgcgga agaccgtatt agcagcggtg gcgctggcag cgtacattgg aaacgcatcg
      481 actaggtacg tcccaaccgg ggtgaaaacc gttatcatgc cgaaccctat gagaaatgtg
      541 cccagaacag gcacgaacca gaagacccga tactcggcgg tccagccata tatgagcaag
      601 ccgatcggga tcatggatcc gcccaggatc gtgggtggca gacggtattc gggcttcatc
      661 tcgccgcctc gggctgctcg cctgacgatt gcatcggaca caagccctaa gataaagagg
      721 ccggcaaatt gaccgcagcc acagcccaga tatataaggc ccacgttggt gatgatgccg
      781 tagcgcgatg caaagacgtc ggttaccgtg gtgaagaaga ggtagagcgt tccatacgca
      841 accgcggtca gcagagatag tccgaagacc acaggcgaga ggaaaagcat cttgacgggc
      901 cggacaatgc tggtggtgat cagttggctc cgggatatgg tcgtacggtc gtcgtggcgt
      961 atgttggggt tgcccgtcga ttttctcagc ctggcggctt tgcgcttcag gagcgtcgga
     1021 gcatgggtct cgcgttgaaa gacgaggcag aagagggaca ctgcaccgga cttgaagccg
     1081 ctattagcgt ctgcccaacc gttccttgta gccagtcatg aggtgggtcg tagcctacca
     1141 cgatgatcag aagccagaag ttccacctcc aacccagcga acgcgacacg taggctccga
     1201 tcgctgggcc caagcaaggc ccaagcagca caggcattgt ccagatggcc atggcacgcc
     1261 cgcgctgctc ttgtcggaag caatccgcaa cggtaccagg accgattgtc agcggcgcag
     1321 cgcctacaag accggttaag aaacggacga tgattagcat aggcatgcta atggacagcg
     1381 cgcaagcgac attgcagaga ataaagagcg cggcactaat atgatagaca atcaggcgcc
     1441 cgtatagttc actgcagggt gccagcacga gaggtccgaa tgcataacca agcaggtaga
     1501 tcgacacgcc aaacgagccg atgtcgcggt tcgaggtgcc catctctacc attacctggt
     1561 tgatagccgg ggcaaacatg gacgacgcaa acggcctggg gagcgcgcgg tcagggttag
     1621 ttccacgact cgtcgatagc cttaggagag gatcgcctca cgtcacaaac gtcagcgccg
     1681 agaccatgac aacatttcgc cattttttgg aggctggcca gttgagtggc agctcaggat
     1741 cattctcgcc gtcccatttg acaatctcgg agtcatcgtc tgcctggcat gccgggtccg
     1801 tcaacgaccc ctccgtcgct gttcccttct cggtgcactc ggtcttgggt ccttgtgcca
     1861 gcacgggggc cgaggagatg ctctgctgcg ggagccggct gttaggatgt gctggggctg
     1921 tcgagtccgt attcgaggcc ttttcttcca ttgtcgtcgc acgatcaaat cgcctcgcgc
     1981 gtgcgttgat tcggagtgga atgatcgttg atatttgggt cagccaaccg aggaagacaa
     2041 gaagaggccg ctgacaaatt cgcctgaagt tactggattt taatttagga tactattgat
     2101 tgtcagggta tagcagcata catttgatgt gccactccgg ctggaaattg tatcggcagt
     2161 ctccccgagc accgtcgggg actctccgcg aagccttgtg tcgcccgcca tttggttcgc
     2221 ccatggcggg ttggagtgtg ttcgtgccag cctgctagta tcgagatgct ctcctgtccc
     2281 ccatgctgac agcattgccc tttgtgtccc cgcgaaccca ctccctcagg atactgattt
     2341 gggcgaaagc ctcacgtcgg ggaggcatcc cggcactgac cctgacgacc aatacccctg
     2401 agccccaact cactgacccc ttgccgacag aaaccatggc tcactatcct cagcatatct
     2461 cggctcgggc cggaggtggt tataagtatt atagcatcaa ccatttctga cggacacaca
     2521 ggctcccctg gtgcggtcat tttagcccgt ctcgtgcttg gaaaccgttg ccaatatggg
     2581 agagatatgt cctcgtaggg aggatttcga tattgattac attctcaaga acgcctcgtt
     2641 acttgagaag gtttcccttc ttgctggtga gacaaagtga cgtgcctggg ttttgagtct
     2701 ctgctaacgg aaattcccaa cccccttgaa ataggctatg acttttggca tacagctccc
     2761 ctaccacggt tcaacgttcc ctcggtcaga gtcagcgatg gtcccaacgg cgttcgagga
     2821 accaagttct tcgacggcgt ccgcgccgcc tgtcttcctt gtggcaccgg cctcgccgcc
     2881 acgtgggatc agtctttgct ttacgatgct ggggtgctca tcggccaaga gtgcctagcc
     2941 aaaggtgctc actgctggct agtacccaca gtgtgtatcc aacggtcgcc ccttgggggc
     3001 agagggtttg agtctttcgc ggaggaccca tatgccaccg gtaaacttgc cgccgcgtac
     3061 atccgaggtg cccagtccac cggcgtgata tccacaatca agcatttcgc cgcaaacgac
     3121 caggagcatg agagaattag cgtcaatgcc gtcatgagcg agcgagcttt gcgcgaggtt
     3181 catttgttgc cctttcagat cgctatcgcc gattccgcgc cgggcgccgt catgacatgc
     3241 tacaacaaag tcaacggaca gcatctttcg gagagcaagg agatgttgga cggtctgttg
     3301 cgcagggaat ggggctggaa gggtctcatc atgagcgact ggtgcgtcgg cataaccacg
     3361 tccgcttctg ggaggtcagc tgctgacttg gccttgacag gtttggaacg tactcgaccg
     3421 ccgaggctct caatgccggc cttggcttgg agatgccggg caccactagg cttcgaggac
     3481 cgttactgga gcttgcgatt tcgagccgca aagtctcccg cgcgacgctg gacgagcgcg
     3541 ccaggaccgt gctcgaattc gttcagcgag ccagaaaggc cgaggtttcg gccgttgaga
     3601 gcacacgaga ctttcccgag gatcgcaggc tgaaccgcaa acttgctgcc gatagcattg
     3661 tccttctgaa gaacgagtcc gggctgttgc cgctcaaccc gcagacgttg acgagtgtcg
     3721 ccctgatagg gccaaacatg aagactgcgg cgttctgcgg aggaggttcg gcgtcgcttc
     3781 aaccctacta cagcacctcg ccgtaccagg gaatcacgag ccagctcccg ccgggcgtcg
     3841 aggttcttta cgagacgggc gctacctcgt atgccttcat cccggagctg gaggcgtcag
     3901 aggtgcgcac gccggaaggc cagcctgggc tgcgaatgcg cttctaccga gacccgccct
     3961 ccgtccaaga acggcgcgtg gtggaggaga ccatcatcca ggagtcctcg tagcagctga
     4021 tgggcttctc caacccggag ttggaccggc tcttctacgc agacattgaa gccgagctga
     4081 ttgctcccgc cactggtcct ttccaattcg gcctggctgt ctatgggtct gccagtctct
     4141 ttctcaacga ccagcttatc atcgacaaca cgactgtgca acgaggtggc acgttcttct
     4201 tcggcaaagg caccctggag gaaacggcca cggtggatct tgttcagggt cagtcgtacc
     4261 agatcaaggt gcaattcgcg agtgggcctt cctccaagct cgtcaaacct ggagtggtga
     4321 atttcggcgg cggcgccggt cgcctgggaa tggttcaggt tgtcgatccg gagcgggcga
     4381 tcgcccgggc cgttgaggcc gcgaagcgtg ccgacatcac gatcctgggg gttgggctga
     4441 cgcgagacca tgaatcagag ggattcgatc ggtcccacat ggatcttcct ccggccgttg
     4501 cctccctggt caccgctgtc ctggacgtgg cgccggacgc cattctccta acccagagcg
     4561 gcacgccgtt cagcatgctt ccgtgggccg accttgtgaa gacgcatctc cacgcatggt
     4621 tcggggggaa cgagctcggc aatggcattg ctgatgtatt gttcggtgtg gtcaatccca
     4681 gtggaaaact cccgctttcg tttccgcgac gaatcgaaga cactccgaca tatctcaatt
     4741 tcggaagcga gcgcgggcaa gtcacttatg gcgagggcat ttacgtgggt tacaaattac
     4801 tacgaaaaag tccgacgagc tgtgctctat ccattcgggt acggtccgct cccgtccatc
     4861 catgttgttt tcggtcgaac tccctgctga ctcgcttcgt ccctcaggca cggtttgtcg
     4921 tacacctcct ttgcgtactc cgatttgacg gtcgacaccg cgtccgctac actgaatgtt
     4981 cgaaactcgg gagacgtggc cggagcggaa gtagtccagc tgtatatcgc ggccgatcca
     5041 acaacgtcgt caatcgcacg tcccatcaag gagctcaaag gatttccaaa ggtggctttg
     5101 cagcccgatg agacgcgccg ggtgagcatc ccatttgatc gattcaccac tgcgttttgg
     5161 gaccaggaag cacacgtctg gacgtgcgaa aaagggcggt atagagtctt ggtcgggtcg
     5221 agcagccaaa acatcctgct ggaaggcgtg ctggagattc aggagacgac cacctggtcc
     5281 ggcctgtgag ctcttggacc gggctggtct cgagattgac acgacaccga ccgcacaggg
     5341 ctacatccag gccgtctgca tacatgccat tgatacgaat tgaaggctct tcgacgagtt
     5401 cgctggatag aaggttataa gactcgtcaa caaccctgga acgttactct cgacaatgct
     5461 ttagcgttcg aagaattcga gaatagagat tgatgggttt gcttctgaac gaagtaccag
     5521 gatgacctgg gaactcaaca gttgtttccg tctcgggaaa attgcctgaa tccccatttg
     5581 taacgaatgg ctgctccagt gtgcctctgt tctctgagcg atccgattga gccgtccgac
     5641 cgtggcttgg cttaaatagc cgggagccac gtctttccac tcctctgtaa atcgtcggcc
     5701 gtcgcgtctg ggtggatctg gtaatccgaa ctcgggcgag taggcgcgag agctctatgc
     5761 cgttgctggt cgacggcttg tcggagttgc tgtattaaag taaaaggatg taggccacag
     5821 aagactttag aatagcttag ttgcctgcct tcaccgtggt tcggcagacg tcgggctgcg
     5881 tgatctaaga tgaactgtac agagtaatca ttcactatcc acctgtctgc cctcttagcc
     5941 tggctagcgg tattatacta tggaaattta taatacacaa tcaaaatact acgacagctg
     6001 aggaaaccac tgataaaccc atcaccaact cactatccag caaggtggat tggtacccct
     6061 accgaattat tgagatagtg gatgaatatg ataggaatac ttttaagccc tcaccaagtc
     6121 cgacttacac cattggcgtt tatccatgac acagtccatt ataccgagtt agcgtaggtt
     6181 aggcactgtg cgctgtccgc gtcttttgtc cagtctcctg gaggatcgtc cgggctcgtc
     6241 tgcaatggat ggttttcggc gaatggcagg ctgggtcaag acgccgtaat gcaggcatga
     6301 catgagatca aatgtcctat ccctgtccat acatagtcca gcgaagtctg tctgtaatct
     6361 gtatcgtact agcggcgtgg gagtcactag tcggtctttt attgaagcct gacctcccaa
     6421 ctcccaacag ctcctgttct cctcatccta cctcgtctcc tataccctac tcgcattcat
     6481 tcattctcag atttgatact ccgagctgcc caccaatatg cgtgaaattg tgagtccact
     6541 cgctgtcttt ggaacggcct gccgtcgaga tcgctgaccg ctgatctcgg ttatgctgag
     6601 taaaggttca tcttcaaacc ggccaatgcg tgcgttcatt cccgttccca atgagaggtt
     6661 gaagtactgc taagcaatga tacttcttcg cagggtaacc aagttggtgc tgccttttgg
     6721 taatccagca taactgtccc gggttctatc gtgcgtcccg ctgacacggc ccaggcaaac
     6781 catctccagc gaacacggcc tcgatgagtc cggcctgtca gtgatccggt cactgtcgct
     6841 tccattctgt ctgaccctac cacaggtgca atgcctcgtc cgaccagcag ctggagcgga
     6901 tgaatgtcta tttcaacgag gtcggcaact cgaaatacgt ccctcgagcg gtcctcgtcg
     6961 acttggaacc gggaaccatg gacgcgattc gctccggccc ccacggagcc cttttccgac
     7021 ctgataattt tgtgttcggg cagtccagcg ccggcaacaa ttgggcaaag ggtcattaca
     7081 cggaaggcgc cgagctggtg gatcaggtca ttgacgttgt tcgccgtgag gcggagagct
     7141 gtgactatct gcaaggattc cagatcaccc attctctggg cggcggaacg ggcgcgggca
     7201 tgggcacgct tctcatctcc aagatccggg aggagttccc tgatcggatg atggccacat
     7261 tctcggtcct gccatccccc aaggtctcgg ataccgtggt ggagccgtac aatgcgacgc
     7321 tgtcggtcca ccagttggtc gagcacgcag atgagacctt ttgcatcgac aacgaggtat
     7381 ccgtcctgat ccttccaagt cgaaatgaca agctaaccag cccaggcgct ctatgatatc
     7441 tgtacgcgga cgctgaagct gtcgtccccg tcgtacggcg atctcaacca tctcgtttcg
     7501 acggtcatgt ccggcatcac agccagcttt cggttccccg gacagctgaa ttccgacctg
     7561 cggaagctgg cggttaatat ggttcccttt ccccggctgc atttcttcat ggtgggcttc
     7621 gcgccattga ccagtcgagg agcccagtcc ttccgcgcaa tgagtgtccc ggaactcacg
     7681 cagcagatgt ttgattccag gaatatgatg acggcgtgca actttcaaaa cggccgcttt
     7741 ctgacctgct cggctctttt gtaagttttt tttttttttt tttttttttt tttttttttt
     7801 tttgggtcct tttctccgcg gcgtcccaga aaaactgatc agtttcagcc gcggcaagat
     7861 ctccatgaaa gaagtcgatg atcaaatgct cagtatccat accaagaact ccggctactt
     7921 tgtggagtgg atcccaaata atgttcagac cgccctctgc tcggtgcctc ccaagggcct
     7981 gaaaatgtcg gccacttttg tgggcaattc cacatccgtc caggagctct tccagcgcgt
     8041 ggcgacccag ttcacggcca tgttccgccg caaagccttc ttgcactggt ataccggcga
     8101 gggaatggac gagatggaat tcaccgaggc ggaaagtaac atgaatgatt tgatgtccga
     8161 atatcaacaa taccaggagg ccagtatctc cgacggagag gagcaaccgt atgccgagga
     8221 ggcggcatat gaggccgagg aataaaccct ctgaatttca ccatctcgtg cgagatcgac
     8281 agtccccttt tcagcttcaa gcttgtcatt ctttctatct ctctggggaa cttgcctgga
     8341 cttcctccta ttgtttccga gactcactgt ctcaaacaga aatagaactt cagtcagctg
     8401 ataatctaac agtgccgttc tcgtcgcatt gtggtcatgg cagaggtttt gtagatattg
     8461 tcctctgtac cattgatcgc atttggttga ttgcaagtga atgtcatgta tacaaaggat
     8521 attggcgtac ataagtcact cgtggaataa aggttgtgcc cggtgtatct gtacgaactc
     8581 ttcggttttc aggtctcggt tttcaggtct tgatgtcaag taaaggtggc gactgtcagc
     8641 catgagagca aacctgatat ttatgaagag cctattttag tacagtatcc gagtgccgct
     8701 cagtaagaga gtcaaggaag aagttggttc tcagctaagc atgaacttgc aacaggccaa
     8761 ggttgaaagc gtttcccgtt actcttcctc gatgtactca tttcaatagc ttatcaagat
     8821 catgtctaca cgagacggag tggtgacaca caacggacaa tgtagcggta catatcaacg
     8881 cagggtcgca ctaaagtatt gacgggtata tctccagcaa tggatgataa tgaaggctgg
     8941 actctaactc gagacgcaag ctgtgggtat ggagtcactt cctcagggta cagctgcaag
     9001 atcgagcact aagagaatga ctagatttta cggactgtgc tccaggtcca acagataact
     9061 gaggacagcg atgtagatgc atgggaatca cgcctgttgc cagaatgact tgggtggaga
     9121 ttacaaccgc attgaaccaa cccacctggc ggaagttgat ttagaatccg tcttcttgaa
     9181 aatctcccct tcttcgtcta atgctaccgc acgagggctg gcttcttatg gtcgtatacc
     9241 ccatttgtct ttcgctagaa atggcaatat gggaacgttt ttggctcctc cagctttcct
     9301 cttttcaccg gaagctaggg aagtggaaga gcatcgagaa accttgtata aaacattatc
     9361 cgtagtgtat gcaatgcccc atcttcaaaa ttgcggatgg catgtgcctc tcagatacag
     9421 gccgtccaat atgacccgct cggcgctatg tgaatgccac aattcattag caaaaggtca
     9481 gtaattggca ctggccatag tgtggatcat tcctcgatcc acaggaaagc atatgcagga
     9541 tgatgaactg ggtaattccc tcggcagggg attacgagtc agaccaggat gcgctctgca
     9601 catactaact aacaagatat gaggggcact ggccagttca atccaacggc acaagctctg
     9661 tctcggatgt tgcgccaact aaacccatag tatgttcatt agctgcctgg ttggacgatt
     9721 ccaacacacc tgggatatat ctccagcccc attaaagcag tgcttgtttc ttgaccgtag
     9781 catgttctat taaagagggg tcttcaatct gatcccccat tgtcgacttg caattggaac
     9841 atattgatct gccctgcata tataacgttc gggaggtcta gtcagtatta ttgagtctgt
     9901 atggatccct ttgatcagat gtacttgatc tagagaagtt caagaaagac tctagatgac
     9961 aaacgacagg tgctactccg tacgttatag ctagatccat tcagtctctc ttcagccgcc
    10021 aattctcgtg ccacgcggga catggataag cataccggcc gagggccatc atgggaaagt
    10081 aatgggcgta gagtgaatat cccatgtaga aatacttcgg gaatccagtg gcggtatatg
    10141 ctttctcgtg ccatgtagct ccctgagaag cagtcttcgt ctgcgtccgc aaaagatact
    10201 ccattccccg ttgaatcacc tctgtggacg gtggcaagta tggcagaagt gccatgatcg
    10261 cccaggcagt ctgggatgcc gttgatggac cagacccagc tcgcgaagga tctttataag
    10321 aatcgacggt ctctccccag ccaccgtcgg ggttctgaac agtctccagc catcgtattg
    10381 cttgattgat tgcatccttc ataaccctga ctcctgacaa cgcgtcgttc tccgagccaa
    10441 agtacgccaa tgcgcagagg accgcacttg ttccgtaaat gtagttgcag ccccatcgcc
    10501 cgtaccagcc ccgagataat acatgtgtgt ctgacaaata gcgtatcgct cttcgagaag
    10561 ctgccacaac gcgatcagca agggcatctg ctttactgag tgcaagaaaa aggccaaaag
    10621 cctccaggac gtggccggtc acatccggag tggagggatc gcacaatgcg tccatgtcac
    10681 tgaacggaat cttgttcaga aaatgcttat cattatcccg gtcaaaggca ccccagcccc
    10741 cgtccgtatt ctgcattccc agaagccaat tcagcgcatc caaaacggag gcggagtgaa
    10801 ccagccgctc gtcttgccga atcattgcca gaactgcgga tgctgtgtcg tccacatcag
    10861 ggtaccaggt gttgaaatac ccgaagctga acccacccgc cttgagtcca tggttgttta
    10921 ccttccagtc cccgtagttg cctaatctct gatgttgctg tagccagccc aacgaccttg
    10981 tgagccaggg cttagaggcc atgcctgcgt cgccgagggc aatcagcatt aagctggtgt
    11041 cccagaacgc ggacacagtt gtttggattc gttttccctg tttgtcacgg tatgcgaagc
    11101 gttcaatggc ctcaagcccg cggtggatag ggcctgaatg cagcggatag ccttccagtc
    11161 tcagggcaag catagctccg tgcagcggcg gcataatgtc tccgatgtct cccatgtcct
    11221 cctggtgctc cagaatccag tcgacgcact tctgaagagc aaagcggcga aagggattga
    11281 aggatcgcaa accgtccaag cggtgcagga tcgagtcagc caaggtgaag atcgacgcaa
    11341 acgggtcgga tctccaggcc gtcggttcgt cgtgattgta tggtatcatt ttattttgcg
    11401 ggtcgcacca cagctcgtcc aagtaatcgc tagaggttcc cttgccgcca cctggaagag
    11461 catagatcgg gcgatggtgg gagatgatca gaaggggcac cacagtagcc cgcgcccaag
    11521 ctgaccagtg atagatactg actggtaccc ttgaaggcag cagaatcaac tcaggcggta
    11581 attccggtac agcagcccaa ggaaataagc cgaacagggc gaggtatatg cgggtaaaga
    11641 tgcggacctt agcaacacca ccagcggcaa ttgcaaagtc tcgtgcacgg cgcattgccg
    11701 cgtcatcctc cgagagtccc aggatcttca aagccagata cgcctctacg gtcaccgaga
    11761 tatcccccgc ctggtcggga gcggtactcc aacccccgtc tgctccctgt gtgcagcgga
    11821 accaggagat gaatgcttct cggtccgcgt cgaggttgat gcctagcgcc tggcagagaa
    11881 ggacatgctc tgcgctggtc gttgcgtttg ttttcacttc gccgcaccag tgtccgtccg
    11941 agtgcatctc tcctctactg tgctggccgg agagcttgat cgcttgcttg attctgggga
    12001 gcaagggatc atcgggagac aagctgcgaa ctcgtagccc ttctgttgtg atggcctctg
    12061 tctgcaacat cgcgagggtc aattggcatc gaggaagaga attgaccaag ctgacgacag
    12121 tccgcgttct atgtcgagac gggatggtcc actacatatg ctacttgagc ggtaacagct
    12181 aacccatagc gacttcttgc ggtgctgtga tcaatggatg gaccataact gtggacctga
    12241 cgaatccggc atgggagcga aaagttaaaa gccttaagct ctattagtat cgcgcccttg
    12301 gacctggtca ttatagatgg tgccatagct tttccggatg ctggacaact tgtcgactcg
    12361 tcatccgtct cggtcagggt ccagacatgg agtatacttg caagatccat gctaaattgc
    12421 ttcaattgta gcagtaatga tgagtgacgc agactccctt tacgtggggc tcgctaccag
    12481 acctctctga ggttgcaagt cctgccatta cagaggtgat gaagatatca ttctcttgac
    12541 tggccgggtg gaagcatccg ggtaagggac ccgcggaacc aacagatggg tcacatcctt
    12601 ctagggcagt gggacagtgg cgcgtatgac agcggtctag aacttactca aaggtagggc
    12661 aaagagccag aatcacttcg agtccagtgt tcatgggttc taccatgggt ccgggcatct
    12721 gacagctgcc gatgtaacca tgtcgcattc cacaagcttg aggatcttca cggtgtaatc
    12781 aacataggtc tctaattagt gtttaatagc tcagtaatga ctgtatatct ctaatccgtt
    12841 cagatataca ggccatctcg aagacagtca ttgtcctgct attgcgctgc cggattggga
    12901 cgagttgcag cgggccgcgg gatacgggtg atcccaggac aggtttggat cgctcagaac
    12961 ggctgagtac aaagctattg tgggtcatct ggccagtgag acatcattct tctgtagtga
    13021 ggcgattgca ccactgcaat catatgtttt gcggagatat ccatgacagt cactacgggg
    13081 ccagtccagc ctcaattccc aggcgagaac agcactgacg actcaaaccg caacatctgg
    13141 tgttgtttct cccaagttag acgcgccaac atgtataaat cccgagtcct cgggctcgag
    13201 tctcagaatg gccccctttg gtaattaacg tcattattgc gcatgcaaat cgactgaggc
    13261 aaggtccact ttatactgtg tacaaagttg ctatacgaag ttggttcggc ttgtcttttt
    13321 caaagactat tcgttaactg tttgtttttc gaagctttcc atgagatctc atgggaatat
    13381 ctgtcccgat aaacccatac tagccccatc ggactcccga gaatggatcc ccctttcaag
    13441 gtcataattg tcgggggatc aattgccggc cttactctcg ctcactgcct gcacagggca
    13501 gagattccct gcattgtcct cgaaaagcgg ccccaaattg ctccccaaga aggagcatct
    13561 gttgccatcc tgccaaacgg ggcccgcatc ctggaacaac tggaggtcta cgacgcggtt
    13621 gagaagctgg tgaagccaaa gcacgtcttg aatatgtatt tcccagatgg attccatttc
    13681 agcgatccgt atcccaagac tatgaatgag ctgtaggttg ccaaatctcg ctttgccttg
    13741 gtgtcgtccg tctgtctgat cagcccctgg tctctgcagc ttcgggttcc caatggcgtg
    13801 tctggaccgt caacaattac tccaagttct gtatcagctg tttcccaaaa aacccgacat
    13861 ctacgtgggc aaaagtgtcg taggggttga cgaacaggat agccgtgtgc tggtgtacac
    13921 tgccgatgga agcacctacg agggtgacct ggtcgtgggt gccgacggag tccacagccg
    13981 tgttcgaact cagatgtggc gcgcagcaaa aatgcgacgg cctggtctga tcagtgaaag
    14041 cgagatgaaa ggtacggatt cttatccgga tcagatcggc gactcagacg ggctgactgt
    14101 gatcatggct gatagggatg agtatcgagt atgcctgcat tttcggtgcc tctcctacgg
    14161 ttccaggatt ggacgagcga cacctgcatt ccagagtaga caacggaaca gcattcatcc
    14221 tcgtccccgg agtcaatgga cgattgtcct ggttcatcat tgtccgattg gacaaaaaat
    14281 atcaatacgg tagtgcgccg cggttctcag tcaaagacgc tgcagcctgg ggtgagcgat
    14341 tgacggataa aaacatatgg aaggacatca aattcgagca ggtgtggcag agtcgccaga
    14401 ctgtcgacat gacggcactg gaagaaacta tatttcgaaa ttggagttgc ggccgcattg
    14461 tctgcattgg cgatagcatg cacaaggtat gtatgttgct gacggaagtg ggtgtgactc
    14521 ccctcgggtc tgacaatctt ctgctttaga tgacaccgaa tctcggacaa ggggccaact
    14581 gtgctattga agacgctgct gccctgacca acaaactaca cgatgctctg aaggttaaaa
    14641 atccaggacg caagctatct gacgacgaga tcgagcaagc cttgtccgaa ttcagcaaca
    14701 tccaagttaa acgcatatcc aagatctaca acgtgtcgtg gaccaccgcg cgcttgcaga
    14761 ctcgagcaaa tctggtgtat aggctactct tgcggtattt cattccatac gcgggagaca
    14821 aacccgcgaa gagagtactg aggattttcg agggagctac agcgctggac ttcatcccat
    14881 tacccacccg ctcaggtccc ggctggacac cgcaaaaaag ggaagaaacg ttctttccaa
    14941 gatggactat tgcgcttgca tttttggtac tgatatcagt ggtgtcaatc aacctgaagc
    15001 ctgttggata ttacagttac tggctgtcgc tccttggcgg cttccttatg gacagaatcc
    15061 gatgacagag caacgctacc tgcctcgatg gcactatctt tctgttttcc gatagtctct
    15121 cgtagtctta gccaaattca tggccaagaa atgttgagga ggacctagtg gagcgctgtc
    15181 ccggttgctc aggccggaag ggttgcgtta cattgctggc aaaccacgtt atggatatag
    15241 gtatgtaacc tcactttttc ccgccaacca gaacgtccac attttgacag tcgaaaagtt
    15301 gaagggctgg ttgatagacc ttaacttatt gaataggacc gtttgttctg catgctgctt
    15361 ccggttcaat cttcgagtgt cttccatgcc aatcatgtcg tactcctggg agacgcttct
    15421 gggccccttg tacctggtga ctcgggcatc tcgtcgtatt tggtgccttt gtatgaaaaa
    15481 ccgctgatta aaatctcagc gtattcggct cttaaagtta tattgcagac gtgactacaa
    15541 gggctacaat gatgacctgt ccattcgcct cccaactcac tcgactcctg taaggtcaat
    15601 taggatttct aattaacctc gacaattcgt ttgaagtaag agtcacgggt ggctacatgt
    15661 ttttaaatag tgccacttct acagctaacc ttatgatgta gtctacagtg atccaggttc
    15721 cgtataaaga gatactgtat tcttattaac aagttgggta tacaccgtcg tgaaacgaaa
    15781 cgatggttag acggctttca ctcacttcca gttcctttgg gcacgcgatt ctattcgggc
    15841 ctgtcgtcct acgggtacct tgctcacggc gggaataccg tggacaattc aggctgcctt
    15901 gatgatggag aaaagcgagt atagagagca tggaaggcgt gtatcatatg tgcaatctgc
    15961 aatataacga agtgtcggtc gtcctatctt cgtcgtccac acgtacagag tctcgaagga
    16021 agggctgact cgggaccatg gccgtttgat cgatggtaag atagaaaggg ttagaaacgg
    16081 tgaatgctga gcatcaacta ttaaagacat tgaaacattc atgattcttc cattcctcct
    16141 cgctgcgtag ctgctgagag ccttctgttc cctactagca gtagtagtat tccttctcgg
    16201 ccagcctctt tgctgtcacg agaaatactc aagtatggcc agttgcattt ccttctgtga
    16261 cacgagactt gctcttcatg attctttcca acatcattcc aatccttctc ttttcgaagg
    16321 aagccaacat cgacagagaa cctcgacatc tatgtgcgag tagaacgacc gcagcggagc
    16381 cggttgcaga ctttcacgcg tggtcaaccg actacggtaa gagctgtgat gtgtcgggcc
    16441 tggagcattt cctgttatgg tgagggacgc aagcgaggag gcttcaaggg ggtggattgg
    16501 cgcagaccat atgctgaaga tttttacagt tccatatcaa caggactaga tgattccaca
    16561 gtctaggtag attggattga attagaagag gccgtggttc ctaattaacc tttcgttacc
    16621 gccatgttga catttgcttc tgctctattg tttgaaataa agctttttct ctcccttttt
    16681 gttagtcccc tataatacgt ggttcaatgc cttccctttc atcatacatg ctctccatgc
    16741 atcttatata atacttgtat acagcctcaa gcgctgtgtg aacgatcctt attccgagga
    16801 agtagcaccc agataatgat catgaggacc aacaatgaga gaatgaacgg ttgcaggctt
    16861 tgcacaccgc gcgccccgga tatcgcacca gcagcaaagg gcagtctacg cccaatggga
    16921 atacacaggt tagcgtgata ctcaaacgga tctcataagc atcgtcacca aggacgcaaa
    16981 cttacattgc ggcaccaccg cctgccaatg atgacgcgag cccaatgccc ggggtatgca
    17041 gatgcttcgg aagcagcttg gccgccacta caactgccgc aggaaagaga gggccggtaa
    17101 agaaaccgag catcgagaca gcaacggcag agacgacaaa ctttgggacc agccaaaaga
    17161 caagttccag ggcaattgaa atagcaaggt atatagtgat ggcagtccgc tctccttcat
    17221 tctagtcagc attcaatcgc tagggctgcg tagaggggat acatgcccaa ccagtcgttc
    17281 acgaagccca gaaccagacg cccgacagtg acgccagccc aaaagccagt tggaaccaga
    17341 cccgattcga atggctttcc gttacgttcc tgaatcatga aatcgacaac ccagccaccc
    17401 accgacactg tcagacttag caatcaggtc atttgctcca gagaaggtca gacaacgcac
    17461 cctcgacacc catgtacaca aacagccagc tggcgatcag ccaggtaatg ggacttttca
    17521 ttgcctccgt ggttcggctc ccaccgctgc tatcggggct cctgcggttt ttggctctgt
    17581 agctaactgc attttcttgc cagaatgtag ccacgctggt caacagttcc agaacggagc
    17641 ccccaagaag agtgtagtag aaatagttcc agtgcaggcc cgacttgatc atctgcgtcg
    17701 cgattgttgg gctcagtgtt gccctgggtc gaccgtcagt attgctgtaa cggtcatcgc
    17761 acatgtttga cgtaccccac accataaaac gccccgagga gccccgtcat ggtgtttgca
    17821 ttggccatat cggcgaccca ggagttccat gcagcgtcaa tgaggccatt gcccaagcca
    17881 acgatcacgt agacggccaa cattaccggc cagggcgggt ggatggccat gatcacgaac
    17941 ggagcgatgt ggcatagcgg accaatgatc gcaatccctc gttgtccaag cgtcatatga
    18001 atcttgttga cgacaagagt ggcaattgcg tatccggcaa atggggtcac gaagattaag
    18061 gagaccacag tggtcgacag tttatagtct tcgcgaagct acatggtgtt agtttctcgg
    18121 tgatgagaat tagttcaatt ctgtgcatac atatgggacg agtgcctggg agagaaatca
    18181 ttagtttgta ccatgggtct gtctatacaa ggagagctca ctccgtagac accgtcgctg
    18241 gctcctacga cggcgaaact ggcgaatgta gctaacacgc gccatttgtt aatgggaggg
    18301 tcattccatt tttgctttgc ttgaacaatg gcatcgtcac cagtcggacc aaatgtgtgg
    18361 actgagcgct gtgactcttg ttgtcctggt ggcgcaagct caaccgttgt cgtcgacata
    18421 ttcgctgttc cagaagagag aaatatgatg agacacaagg agccagatgg cgacgagaag
    18481 attacgagat attagtgctg ccacgagtca ataaatactg ccttgagcat ctttccccac
    18541 ttgatgagtc aagaacttgt tctttcttct tggaagctga cccactgagg cagaaccaga
    18601 acacatctat ggacagccaa gtctttagcc tctagactat ggatgtgggt agaaaggtgt
    18661 ttcactgccc tttctgacac ccaagccaca gtgcctttta acgccttctg gaagttggca
    18721 gctgcatcta cccacgtttc tggagtgtgg aatttggagg atcaataagg acattgattg
    18781 aacacactga aggcacagct gacttagcag gtatttttaa ggcttccttg tgcattcggc
    18841 agtggaactg tcgcctaaat ctccgatccc tgtcgtgcta ccctttgtct gtgccttcag
    18901 tgcgagctca gaggttcact atgccgaatt actgaaccgt aaatttattg gccaaagcga
    18961 tcggctcctt tggccggatt caagcctaag tcctgatcat acacttggtc agcagaatca
    19021 aaccataggt ctaatagcaa aactgtatat tgaccaagat tgcacctgcg cgccaccact
    19081 agtgacacca agatagatga cgtataccat actcgggagc caagtcaagc aatagcaaca
    19141 cagagcgaac agtgattgtg atagactcaa gacgcacaag tagtttaatt agctggaagg
    19201 ctacccttta catgcatccc atgagtttcg gctgtgtaat ggattctcgc acttggaggg
    19261 gaggtgattt gctcatgcca cacggcctga tatccgggtg ctctcaataa ttctgcaaat
    19321 cttaaactgg ctaggagtgc tcattagcac atatgctgga gaggcggcac cggggaagag
    19381 acctggaaat tgcgagatcg ggttgtttgc agtccggtct attatgccat cctaagtatc
    19441 catgtaatac tttgaagggc gctggattat gacgcaacaa cggtatcagc tgcaccaccc
    19501 tcaacttttt gatacatgat atagaatcct cgaatcttgc tgtttgcttg ggataagcgt
    19561 tgagtttcaa aattctcgcc gagcactgat taaagataaa tatgcatgag ttatatgggt
    19621 acctgtgtgg aaggggagga attaccgtgg gcatttccct ggtacaaact gcaatttcct
    19681 catttctggc tgttgatggg tgtaggttct gacaagggat aggtggtctg ctatgtaatc
    19741 acccaagccg tctataacgt gttcctccat cccttaagtc gcttccccgg cccactattg
    19801 cacagggcgt cgcggctggc atatgtctat cggttgatcg gagggacgct taccttggac
    19861 gcactcgaaa tgcatcaacg ctacggagat attgtacgag tcgcccctga tgagctcttt
    19921 ttcgcccacc cagatgcctg gtcggacatc cacaagaaga ctgggaggga gatggataaa
    19981 gcgccatggt tctaccggcc tttagaacag agcccacgat gcattgtgga cgaaagccac
    20041 gagcagcaca gccggctgcg gcgacaaatg gcgcctggat tctcagagaa atctatgcga
    20101 gaccaggagc cgatcatccg gggttatgta gacctcctgc tgcaaagatt gctggaaaag
    20161 agcaatgacg gtcagcccgt tgtcatctca gactggttca actacactac gtttgatata
    20221 attggtgacc tggtcttcgg ggagcctttt gaatgcttgg ggtcttcgaa gtatgatggg
    20281 tggatcaaga gtatttttga atcccttcgc cccttaacaa ttgtgcaagc tctctcgttc
    20341 tttccatggt tgaaacgaat tgccctagac acggtcccga agaatctgca aggagatatc
    20401 aagcaacaac aacagcagac agaagccaaa atgcggcgac gcatggctgt cactgcaagt
    20461 cggggggatc tgatggaagg attgctcaag aagaaagacg aattagttag taatttggcg
    20521 ctttgattca ggaatcgcat tggcactaac ggccgtccac tgacaaactt acagcacctg
    20581 agcactgaag agcttattgg taatgctcaa gtcctcatcc tcgcaggttc agagacgact
    20641 gcatccctcc tcagcggagt tatctatcta ctgctccaga atgcggtggc ctatcggcag
    20701 ttagttgatg aggtgcgctc aacttttaac agcgagaaag acatcaactt tgtcagtgtc
    20761 agccaactgt catacatgct ggcttgtttg aatgaagctt tgcgcatcta tccaccagtg
    20821 gcgaacggtc tgccgcgtgt cgttcccaag ggaggagctc agattctggg acagtatatt
    20881 ccggaacagg tccgaagaca ttgatatctt gatgattaat gagcgatatc attaactaca
    20941 tctacagaca tatgtggcta tcccccagtg ggcgctctac caccgcgagc aatacttcgc
    21001 tgagcctaac gatttccacc ctgagcggtt cctgggtgat cctaagtttg cgaatgatcg
    21061 acgagatgcg ctgcagccat tcagtgttgg cccacgaaac tgccttggac ggaagtaagt
    21121 cgacctacat gttgtatcgg ggaagctgat tgaccatatt tagccttgcg tacgcggaaa
    21181 tgcgtttgat cctcgccctt gtcatttttc actttgacat gaagattgat cctgactgtc
    21241 gtgactggat ccagcagaga aatttcaccc tctggcagaa gcctccactt aaagtctacc
    21301 tgaagccagt tgcaaggaag tcagagccta atcaggtgta atgagtagtg gactatatca
    21361 gtgcaccacg ggcagaggac tacacatcta cactggtgat aggaaccggc acatatggat
    21421 ggtataaccc tcgcctgccc acggaagtcc gcgaaatggg atctatcggg atctcatgca
    21481 ttgtgccttg gcaggggtaa ttgttgtgtg gaaatcccag gccaggaacc aacacatcag
    21541 gtcactgggc aggactatgg cgaaattcca cagtcaagca atttgtgcag tggcaccttg
    21601 aagaggatca tgcatcaagc cagatagatt tgcaagcaac tgtagcaagg cagacaacca
    21661 tcagcatcga gggcatttaa ggctattact tgccgttaat gcttcattta gcaaacagta
    21721 attaatatct gccgagcaac atcatccagc acctgaagca tattatgcta gtcgatcgca
    21781 agctgaactc ggagcgaacc aactgagctc aagagaggtg cggtttcctg ccctggagct
    21841 ttgtaggatt cggtaaaacc atcaaatatt agtaatcact aatttaagga ttgcttaaga
    21901 aatttgaatg ctggcagttt gagtagacct gcagcagata agttacttga aagactgatt
    21961 ggctagaacg gaatgctgat gcggcacaat actactctag cgaaccaagg gatcatcttc
    22021 agtcccagaa tctgcacagg acggaccaaa tcaagtactt ggacagcctt gtggacagtc
    22081 ttcgacccgt tgcagccaga taaccaatga tgtaacactg aagaggatcc tacagttgta
    22141 tccacgctgt cgcagtatgt taaccatgcc atctcacgaa aatgtgtcca gacacgaatt
    22201 caggcataac ggtaaaacct agattgtcat tcaataagct cgtcatcata tctacaccct
    22261 gagtcccttc cagccgatga tttctgttcg tttgctaggg cccgaccata cccagcgagc
    22321 tttttgaaaa acgaggacca cctcacatat agtctactca agacttcaac tacccaaatc
    22381 ggtgcatttc tagtctgaag aagcctgcag tgacagatcc tcctgacact accgttgcca
    22441 agatgggctt gatcgagggg ctgcaggcgg ctctggacta tctcgagaac cctactgcac
    22501 tcactgcaac gagcgtcagc atgtgtctat gctggcttgc tacttacgct ggaatggtcc
    22561 gcaaatcgtt tcaggaccgt tcctacagca tgccattgat gccactttgc tgcgatatcg
    22621 cctttgagtt cgttttctct gtgctttacc ccccgacgga ggccccaatt ctgcagtatg
    22681 tctttggaag ctggatggcg ggaagtgtca tggtggtgtt cgcaactata aggttcatgc
    22741 ctaatgagtg gaaacatgcg ccgctagtcc agcagaatat tctctcgata ctcgcggtta
    22801 ctattctggg ttggatgacg gcacatttgg cgttagtcgc ccaatttggg gccgatgatg
    22861 gatcagcctg gggcggttgt ctctgccaat tacttctggg tgcttgttcc ctgtgccaac
    22921 tgattgtccg gggaagcagc cggggggcat cctttttcat ttggtatgtc agggaacaca
    22981 agtgatctcg caactaggtt cgtaactcat tagtctctta ctggttgaca ggctcagtcg
    23041 ctttttgggc actaatcttg gtgtactgta ttttactttg cggtttcgcc acgggcatgt
    23101 tatatggcac agtccgttgg catggtggag ttcagtcatc gcctttctga ttgacagttg
    23161 ctacgggatc cttctctggc atatccgaca ggctgagggc agggaccagc agcagagaaa
    23221 ggctggatca gagataggac caaaatgaag gggcaaaagc tggaagctgg tgaaggttac
    23281 gggtaattcc ctggtcgccg gaccatctgg caatcctgtg tgagccatcc gcatcgacgg
    23341 ttgtccttaa aacgatctgg gaagtccgag gagtgggaag gcaaccagca agtctggctg
    23401 aaagtgttgg agtggccatt gaattaaaag agtatatctg ccagaatatt gatgttccag
    23461 ggtactgtta taatggccac tcatttgact gaaccaggaa gacttacctc gctgctcgtg
    23521 gtcaacatcg aggaatcctc tgctacactg cctgaagtaa aaccaggccc catcattaac
    23581 cctctaacca ccgtccaggt cattctggaa tcacttttac tgccaaggtc cataggagtg
    23641 ggtgctagat gggcaaaaag atagaagatg aatgacaagg gtgggattcg aacccacgcc
    23701 cctttcgaga cacggaaact gatgactcag ttttaaggtc cagttcctga accgtgctcc
    23761 ttggaccact cggacacctt gcctgaactg atcttctgtg tcgttattat gttatacctg
    23821 gcattactta ttgccagaat acgtacaaac tgatctgatg caggctatca gatagaataa
    23881 taattctcag catagtacat tccccggcat cttcataccc ctcagtgact gcgcgtacct
    23941 gccaatagcc atcatgacga aacagtgcga gctataggag gagctcttgt gggtgcaggc
    24001 cggcgaacaa gccctcgttg gctgatcctc cgtccatatt gcccctccaa caacggcctt
    24061 ggtctgcgtt cgtagcaaat acttcacgcc atctcgaagg atgctatcaa taggtgacag
    24121 ataagggagt aacgccagaa gcgccaaggc cgtctgtgac gctgtggacg gcccaccttt
    24181 ctctctccag catatgtcac cccagcctcc atctcgattg cgggcgctct caagccagtg
    24241 gatcgcttga gacacgtcgt cgttgatact gtcatctctc tcggtccatc tgttgcgctc
    24301 tttgaccccg atgaaatagg ccaatgcgcg gaggacagcg cttgtcgcgt agatgtgata
    24361 cctggtgcag cacccaaacc aggcaccgca gggttgttga gtggcagaca ggtagtgtat
    24421 tgcccttcga gaagctgatg cgacctgatc gaccaatatc ccttgcgcaa ccactctcgt
    24481 gtcccgtcga ctcacagtca gaagcaggcc gaaggtttcg aggacatgcc cagtcacgtc
    24541 tggcgttgac tgacgcacaa gcttgtccgg tgaagttcga taatgactgc tgcttagaga
    24601 tgtccatcca ccatccgcat tctgtcgctt cagaagccat tggagagcgt tggcgacaag
    24661 gtgtgagcgg agcatgagag gatcctgtcg aattaccgcg tgaatcgctg atgccacatc
    24721 atccacatga cagacacgag tctcaaaagt cttggatgtg tcactgttaa catctggaag
    24781 caaacaacgc tgcagccatt gtacagacgt cctgaaccat ggggcattca cggcgatgcc
    24841 agcatcttgg agccccgtaa tcatgcgact gctgtcgcgg aaggttgtat tcacactcaa
    24901 gacccgcttt ccacccccat cctcatacac aaagtgtccg atattgtcca gagtcgtgcg
    24961 tagagaacga gatgagaccg agtaaccctc cagctccaat gcaactatcg ccatgtgcag
    25021 cggccgcgac agaggcccga cgccgcccat ttcccgcacg gtctgaagga tgaacgcaac
    25081 actccgatca agcgcatagc gtcgcagcgg aaggatgtat tttagcaagt ttaggagatg
    25141 tacaatcaag tctgtggagg ttgacgccgg tgcagtgtcc ccgcaagtgc caggcgggaa
    25201 agcgcaaaag gcattctctt gcggttcttg tggtttgcat tgcaattcat gcaaatatga
    25261 gctggctgca cagtcctgaa tgggtaatgg aaagattggg cgatggtggc agaggatgag
    25321 gagagggatc agcactgtaa ggtctacagc tggccagcag catatactgc tgaggatata
    25381 ttgaggcagc aataccaact ccggaggcag acttcgaacc gcattccaag gatataggcc
    25441 gaacattgca agatgaatgc gggtgataaa gcaaacattt gctatgcttc cttccgcaag
    25501 gataaaggat tgagatctgc gcatctgatg cacattccgt gagacaccta gaattctcaa
    25561 ggcaagatag gcctcaaccg taaccgaaag atcgccacgg tccccggggc tgatgcccca
    25621 tgagccatct gagttctgga cagaataaaa ccatgaaatg aaagcatctc ggtctgtatc
    25681 caagttgctg ccaagagcct ggtgcatgaa gatatgctct gcggttgttg cgatgctgtt
    25741 gatcccggtt tgtccacgcc agttgccgcc cggtctcctc tgaactttgc tatattgggt
    25801 ggctaactga agcacctgat tcgtctctga caccaggcgt tgttgctctg aaggacagcc
    25861 agccatcgca gtgggttgcg accccaactc cactgtacga gacattttta tgtggatatg
    25921 tggttgaaag gccgacaagc agcacccagc aagcatatgt atatctacac cgtcgtgcaa
    25981 atactagact tagaactttc gccggccttg cctgccgcct cactgataac tgcatactgg
    26041 ataccaaagg cctgactacg cttacacttt ggtcttctcg gagacattgt gcctctagcc
    26101 tggttttaca gttctatgat ccgtatatca gcacagtaga cttcaatccc gcagtctcct
    26161 cccctccaaa cgagctggtt ggatcaaggg ggttttcctg gaatccacca tgtaaaaatg
    26221 ttccacttcc gtggaatggg actgacatgg acgccgcccc attaacttat cttgatgtag
    26281 gtttacttct tcccgtcaat aaactttcta cggggtccat gtgtaggatt tcgaattggc
    26341 ccctgaggtt gatcatgctt gattaatcga tgtcatgtca gttcgcccag gtggcgaacg
    26401 tcgtagcagt accggaaatt gacctcgtct tgtttctaga agggcccatg taggattgat
    26461 tgtttgcttg acatgcaatc ggctgcgcaa gctgaattag cctctggtca attgacatcc
    26521 tagagatgca acttgttggc aatcaaggac gcaactggta ggagattcca ttcggccctc
    26581 taccagtacc ttggtctaga ttcttagccg gagcatgcaa gggactttgt gtgacatacc
    26641 atccaccccc atgcaagaac tgggaaagtg ctgtaagagg acaggcagtc gcattagtga
    26701 taccctggca gaacccgact gtaccacgga tccttgacgg ataccgcaat aaactcagcc
    26761 tgacagtcca tgacatctcc ttatccacac tcaaggcagt gcgccccagt gcggaatcgc
    26821 tttactcttt ccttgcctag catgcctgtg ctatgaacca tttctcactt catagagcgg
    26881 ggggcttctc agaatgtcat ctctggaatc tatgacctca cagtgattac ctgctgaggt
    26941 agtctttttc ctttctggag tacgctttga cctcgaggaa atgctctgtg accgtgtgca
    27001 tctaccgtca acgtagcctc tccgtggatt ccgaatctgc tcaagcctta atctgacaag
    27061 atagggctga agacgtcaag aaagacatga cccgaaacag agagttccgt gactgagacg
    27121 gctgcaaatg acaacagacc agggcgtact tgcttagttc cactttccct taaattgaca
    27181 gaaataacgc agggcatgac cttttcgcgc ttggcaagcc ccttctattg caggcttgtt
    27241 ctgcagaagg ggatactcta ttatttctcc aaaaatatca atcttagaag ctatactgag
    27301 cctactagct gtactctatc tcctaccaca tactcttaca gtctacattg tcagttcata
    27361 tacagtctgc atcatatgca agcgctttgg ctttatacca gcctctttac tccagtacga
    27421 ggcaggtaat taggtgagaa ccctgtcaag tgagtgaaag taatgactat gctcactcct
    27481 agctagctat attcaacagt gccattaagc agtattctat ccttgttgta caataatgag
    27541 ctagatgtga atttaaatat atatgagctt cagggattac acagcttgtt tctctttgtg
    27601 cacttgtcta gcataccaag gattaattct gtatctcata tcattcggtg cctgtcatca
    27661 atgtacgtga agaccttgat agagaatagg agagactgtc cgtagtaaac taactacatt
    27721 ctttccaact aacacagcat atgtagattc agcagcgcat caatatacgc taagactaat
    27781 gaccccatca gtatcatcac cttcaatcca ggtcaatagg cagttcaagc caccccagtc
    27841 gagccttata gcactgtagc aggcttttag ttaacctttt tcaaacacac tcagacagtg
    27901 gcactcaaca atacatgtat atttccgcca caaattatcc tctcgcgtct ttttttaaga
    27961 tgttcaatat catggttacc acaatatagg cgatgattag tttgagcaga tgaagaccag
    28021 atgacgacca gggctcatga gtacggcgtg tcagtaagaa ataatttaat ttatcttcca
    28081 aagaaagaaa agctcaccgt gcatgacatg acgtctggag ccgaaaggta gatatatcga
    28141 cttagttgtt accctagtga tcttctacgt gggcataccc gcgcttgggt ataccttttc
    28201 ctgctcggac tcatgccatt tcccatatgc tgctcctctg gtatgactgt ccttcgtggt
    28261 agaactcctg gtccctatgg acatccaagg tgggcgcggc aacccacata ccccatggca
    28321 gttgtggcct atgggcaagg taatcccaga tggatacatg acttcccagt cggctgcata
    28381 cggaaacaca gagtcagatg tactgtttcc cggacagcac tatctatgta gtggagcttc
    28441 ttgaaggaca ttggggctcc ccattcttcc tctgaactgg ggactgttgc agcttcttgc
    28501 cgaagccgct gatgcaatct gttttctggc tttgagctgg taatatccga gatcgcagcg
    28561 gaggtaggga cgacagtcag atatgggaca cctgctctgt ttcctcctgt ccagcctctg
    28621 agaaagtgcc aagcagcagc tgtaagaact aagagcaccc taaaacggca gtccatcttt
    28681 gatgccgtta aaccaacata tcggtcatat tccttagaca cgtatcctta tacgcttggc
    28741 ataaatgcta aggctgcttt caaccccagg gttattaggc tgtgtcgtaa gcttcgaact
    28801 cggtaccatt gtttgcgtca aactcgcctc atacgggact gacatgagcg agacgatttt
    28861 cagtcataac agatacccaa gaaaatcact ctgcagaagg catgcctctc atgacagtat
    28921 acagccattt atttcgtgcg cagtatgcaa caacccatgc aaaagcagca gggtactcca
    28981 gccatgtggt gtgccagtgg accacaggca catctgacgt tgaagctact cgaccttaca
    29041 tccaagttgc cgtttggaca ttgggtgtaa tggctatcgt tgtattccaa ttcagcccaa
    29101 tatagatgtt gcgtaggcga taatctttca gcgatataat ggtgaaaact tgttgcatgt
    29161 cgcactactg agccgcaccc acgcggccag ctttgctagt tccgagggca aagagcgata
    29221 catcaagtaa tcaaagatct caaaaatttg atggagctcg gcttggattc gtttcaagaa
    29281 ggtcacaaac aacagtctgc tgcggtgggt tcatttctgt ctggggtcat gggtccatcc
    29341 tccgggtata ggacgtcgca gccccaaaga gtaaaagtgg cattcttgct ctttttcaga
    29401 agaagacaga ccaagagatg gcgcgaggtt tgcaggcttg gttaactcta aattcacatc
    29461 agattagcgt gatcagagtt cttgccaatg aatcaaccta ggacatgata ttacagaaca
    29521 gcagtaccta gtcttctacc ttcgattcaa gtcaccctct ttaacagaga agttgaaaac
    29581 ggctgttagt tcaatcgaga tgcatgatgt ggtcttccga gcttcaaagg atcatgatat
    29641 cctccgttct gaaacatgga tggccccaat gtcatttccc cttccagcgg tctggatatc
    29701 tccccaagtg accgcacaat acaggcatgc caaatggcag actctagatg ggattttgta
    29761 tacagattat ctacttgaaa cccaccaagg gactgtcctc ttgccaccat tccgtcttcg
    29821 cagccgctat ttcatgtatc tgacttagtc tagatgacct tctgtccgtg acgtttagta
    29881 gctactattt cccagctcgt ccagtcccca caggttttct aggttctgag ttagtgcttc
    29941 atcttgtttc accttaatcc acataaggta ttgcgtacgt actcaatagt atacatgata
    30001 cagccctacc gattttagta ggggcctgta agcaagagca attcccgaat taccgcgaat
    30061 gagagtacct ggaccccaac tgtgtcaacc tccaatccca caatcagggg acaacgtcgc
    30121 tggactccct gagttgtccg cgagggatcc acaagatcct ccaacataag cttagcagct
    30181 cagtgccctt aacttaagac tgtttcgacc gaagcacaga ccaggatgac gcgtaccaca
    30241 cactatttat gatactgcta gagtcgagaa ctcgctcacc aacggcccga gtctaacttg
    30301 aatcactggc gccagctcga gtcagtaacg ctgccaaatg cgttttggct tttcttggca
    30361 tcatttatca atcagaagca ggtggcgcct ttgttgtttc acttgctcca gccgtccctc
    30421 cactgcagtc gtcagtcgtc tgtgacgacc tggcagcttg tagtgggcaa tggcgctgca
    30481 ggacgatccc tgggtctaga cgctggttca ttgtgtcctg cctctgtcga gcagagtctg
    30541 taggtcgaag caggtgtttg tctctcttgc tcatcgttgc gagtgttgcc caaatctttc
    30601 tccacctgac gatccctcta agctgacgtg taccagcttg gtggcttcag tgttgaagca
    30661 gtgtcaaagg tggaggaagc atggcacaga gaaggtctcc atactgagca gactcagtat
    30721 ggactaatgg ccctatttgg aaatccctag tcgactgcat gcctatataa atgccgtcaa
    30781 atccgctctc agaatcccta ttcttctcct catagtcccg gtgactccag aatctagcac
    30841 acaactttcc attcttttca aactttcaca ctcacactct ttgacttcaa ggcctggttg
    30901 ccatcttcaa tccttccact tcgaatcaga tcttctacgt cacataatcc gtccattcta
    30961 tccacttcac aatgaagcct cagactgctg ctttcctgct cagccttctc ggctctaccc
    31021 tggctgcccc catccagcat gccgacaaag ggtccgatgt aaagcccact cctaccggac
    31081 ggggcgctcc tggcggattc ttcactggct tcccctctgg tgtcccctct ggcctgccat
    31141 ccggtttccc tggtggtcca gtacctggag gatttggtgg cgatggcccg aacggcccca
    31201 ttccatccgg ccctgctccc tctggcgctc cccaaggtga ggagggcagt tcttccttcg
    31261 gcggccaagg agttcaggcc cgctcgccac aggatttcga ggactcaggc gctgctccat
    31321 ctggagctat tccctctggt gccataccca ccggcgctgt tccctcgggc gctcccaatg
    31381 gctttggcgg tttcggacag ggcggtcacg gcggcccagg aggcccaggc gaggaaggct
    31441 ctggtccttc tcctaccggc gctgtccctt ccggagccat cccctctgga gccgctcctt
    31501 ccggcgcagt tggaggcttt gacggcttcg gacaggcatc tgagaactct ggcaacgccc
    31561 agttccaatc ttctggcacc tcgccatttg gtgcttccca ttctggatcg gctagcggtc
    31621 atcagggcgg ccgtcacggt ggtgactacc gtggtcagca cggcaacggc tctggcgcga
    31681 ttccttccgg tgctgctcct tctggtgccg ctccctctgg cgctgcggga ggtttccctg
    31741 gttttggaca gggcggcgag ggctctggcc cctctcctac tggcgctgtc ccctctggtg
    31801 ctgccggatt tggtggtcag ggtcacggcc agggccaggg ttcattcccc accggcgtcg
    31861 ctccatctga cgtcccctct gctcagccta ctgcttgaag cgtcgacaat cttctgagga
    31921 gataatgggg tactatgttg ggcctttggt caagcaatgg agttggatca cggcctgtat
    31981 gtctgatctg ggggactggt acaagtttga gagacgtggg acagatctgg tgtataatat
    32041 ataagaattc agaaacttat cttcaatcat aatgtgctca gaaatcaagg tacttcatca
    32101 cccagacgga gtcaatgaca tagagatatc agatatccga tctgaatcga cacaggtttt
    32161 gtgcttgcac ttcttgtagc tcccaccatt tgccaatacg ctcacggtcg aagcaggata
    32221 tctaatagat catggtcgta cttgcatcgt gttggtcgta caagcaatcg aactgatgga
    32281 atcgcaccca tgggcccagt ccccttaaca tcaacacttg gctggcgttg ggtgcatggt
    32341 ccggtcaacc acaaggaact gggaccctcc aagcattcag tgactcggcc tcataggctt
    32401 gtgtaacctg ttacacctgc tcagatggca tgctaagcgg taacctacca caaagcaagc
    32461 ctcccgtttg gtcacaggag tcgggttcga ttgatcgcgc ttggtcgctt ttggtgctcg
    32521 aaattaactc gcaatttgtc gggtgtttct ctacattttc caagtatgac atgacgcgtt
    32581 ccaccagtat cctcctcggc tcggcttgat cctcatcgct cagcgcatgc gaggcgttcg
    32641 ggatgatcat gctgttgctg tcccaacggt cgccggctgc cagggaccat cgcttcaaca
    32701 aatgctcctt gtcaacccac ggtggcaccg actggtctct tccggaatac aagactaaca
    32761 gttttgaacc cagcagaccg cgcgacccca gctggccaaa ggtcttctgc atctggtcat
    32821 cggtgaggtc ggagctgaac aaatcgtctt cttccggttt ctctggacta tctgggctgg
    32881 ccaggctcag aaaccgtcga ctgctcacgg gtgttgagct cggatacccg atccgagttg
    32941 ttgccgacag ggggaggatg gtgtcgaggg tgtcatcatc ttcataaggg gtagatcggg
    33001 cacgcgcaat agttctctgg tatatctcgc gcattcttcc cggcccgtcc ctatccgttc
    33061 cgtctcggat gacccaagtg atcgcttccc ggtctgagac aggcgcttgc atgacggctc
    33121 cgtcgacggg aggccgcttg ggaggttcta ctgccgcatc cttgtccagc accgggtgac
    33181 gcggtcgcgg attcgcacaa ctcaagtagt gcatgacatc ttgactgccc gtcgaatgac
    33241 ccataatcac gatcttccct gcgccgaata acccctgctt gtactcccga gcatactgca
    33301 cacagcgcgc aatctcatcg atgtctttgc ccaaatgacc cactccccat ccgctatacg
    33361 aggaagagag aatgggtgag aaaacggacc agggtgtata ttccagcgct gtaatgatgt
    33421 cggtcaggta ttcgacagtg ccgagtccgt cgcccaggcc gccgatgaac acgagggtgt
    33481 ttggttttct aacgaggccg ttggtatact cgaaagcgac caatccttca cactggtcaa
    33541 ttgatgagtt gttagcgtgt aagtcccaaa gcctgtcgga tgaagcccgc gcgtcttacg
    33601 gagtacatac atagggatgc agaatacccg catggccctt ggttcgtggt tgccgcaaag
    33661 gaagctgcat tttgcggtcg caaatcagca gaactggcac aaccgtaccg gttatatttg
    33721 ctgtatgctt tgctgaatca agagagatga cactgggagt gatgaagaga acaggagttg
    33781 tttggcgtct tgacagagga agggagaaag ggaagattcg ttggagacag cttcaccagc
    33841 cctaccggga aaacctcggc ccgcagcagc tgtggtagac tgaattagga cgaatcattc
    33901 aaataccatg gtatactgat ccaactgtat accatgtacg tataaataga agccagatgt
    33961 gcctgtgtca ttacatgcta cagatgtctg atctacaatt tgccctctcg tttcggttct
    34021 gtcaggatct gataagatta gatgcagtag gatctacaga gtacaaagca cttggcctaa
    34081 cccaatcggg cgttccgtgc cggccgcaga ggaattagac tactataatt acttttggta
    34141 tatgtacaaa ataccggtat cttgctgctt catctgactg tgacaacact accatttcaa
    34201 ccccttcaat tttaacggaa ggtgaagcaa ccgttgcccc gactctgtag gtttcggcaa
    34261 tcgccctgcc cgaatgttca tctgcagtga ctggtgaagc agcctcggct ccgccagctt
    34321 cgagtcacgt tccttccgga gcgtgacaaa ttcctcttcg gtaacgccgt ctctaagatg
    34381 tttattttgc tgcctatgct catggacact cagcgagggg acgggctcct tgcgcccttc
    34441 gggaggatag tcatggcccg tccagacctt gacgtgatcg ggcaggccca agaccttccg
    34501 ccctgaacga tagaggttgt ttgcactgcc gccagggaaa tcgcagcgtg cggtgccaat
    34561 atccgaatgg aagatcagat caccgcagaa aacattgtct agccggttca attagcaatg
    34621 cgacacaaag tcaatgggcg tgactcggca tacctccaat gcggtatccc aaatggtctg
    34681 gcgtgtgtcc aggaagatgg atggcctggg ccatcagatt gccaatctta aatgtctcat
    34741 cgtcctcaaa caatttgtca aagacatctt tatattcctg ttcaggaatg ccatatctct
    34801 gcccaaacaa cttctgcacc tgcccgatgc gcttgccgat cccgattcgt ggccggtggc
    34861 cttgctcctc ggccaagcgc ttctgcagat acgacgctgc agtaagatga tctgcatgtg
    34921 catgggtttc aagaattcgg tcgactttgt atcccttctc cttgaccaag gacagaagcg
    34981 cgtcagcgga ctccgtggtg atgccctggg tagcggggtc atagtccagg accggatcga
    35041 tgatgacggc tgttgatgtc gttggatccg ccaccacgta ttgccaggtg cctgtcttgc
    35101 tctcaaacac atcgtgaatg gtcggttctc ctggttccat ggttgcagtg ctatacgtta
    35161 ctcgatgaac gggcccattc agggagcttt tgctaggata ggcgcgatta ttcagagcac
    35221 ggacttttga cagcggtctt gtatagactg ctaacggtct cagatgcact tttccagtcg
    35281 tgtagggcga cttctgtgta gctctataag gaagagggcg cagtggcact cggactgcag
    35341 taggaggcgc cccgaacaga cccgctgtta cttgccaatt tctgcagatg tgaggttgaa
    35401 tcgatgccat gttcaaatat gtctgcgctc aatagcagtg ccaaagacac atgcgatctg
    35461 cagctgttta tacatccctc ggtctctatg cagccaatgc atcggggatc gacctgtact
    35521 cactcggcga tccaagcaca tgactttgaa tcggcgactg gcttctatgc atgacatcac
    35581 tatttatgca gctgacataa taaatgccaa gcataacgaa cttaaacgtg gtcgccgata
    35641 caggggcggg tgggcccacc gggcttatca gaatttctta tcgcaccatt cataatcgct
    35701 cctgattgcg acatccgggg ccctttttat cggtcgtatt tctgtaatca tcgtgccgtt
    35761 caactcttgc ttccttttgt tcacttgcac tccagttctc ttacatcttc cggtctcata
    35821 tcatgtcagt catgtttcgc agccgcgtaa cagtggcagc ctctgctgct gtttctcact
    35881 cggtatttgc tgcacagaat gcctcgacgg taacgcgggg tttcgcgaca gctgcggtgg
    35941 gcacgtcgcg caatca
//
