LOCUS       CM000173               32958 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 5, whole genome shotgun
            sequence.
ACCESSION   CM000173
VERSION     CM000173.1
KEYWORDS    WGS.
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
REFERENCE   1  (bases 1 to 3948441)
  AUTHORS   Nierman,W.C., Pain,A., Anderson,M.J., Wortman,J.R., Kim,H.S.,
            Arroyo,J., Berriman,M., Abe,K., Archer,D.B., Bermejo,C., Bennett,J.,
            Bowyer,P., Chen,D., Collins,M., Coulsen,R., Davies,R., Dyer,P.S.,
            Farman,M., Fedorova,N., Fedorova,N., Feldblyum,T.V., Fischer,R.,
            Fosker,N., Fraser,A., Garcia,J.L., Garcia,M.J., Goble,A.,
            Goldman,G.H., Gomi,K., Griffith-Jones,S., Gwilliam,R., Haas,B.,
            Haas,H., Harris,D., Horiuchi,H., Huang,J., Humphray,S., Jimenez,J.,
            Keller,N., Khouri,H., Kitamoto,K., Kobayashi,T., Konzack,S.,
            Kulkarni,R., Kumagai,T., Lafon,A., Latge,J.P., Li,W., Lord,A.,
            Lu,C., Majoros,W.H., May,G.S., Miller,B.L., Mohamoud,Y., Molina,M.,
            Monod,M., Mouyna,I., Mulligan,S., Murphy,L., O'Neil,S., Paulsen,I.,
            Penalva,M.A., Pertea,M., Price,C., Pritchard,B.L., Quail,M.A.,
            Rabbinowitsch,E., Rawlins,N., Rajandream,M.A., Reichard,U.,
            Renauld,H., Robson,G.D., Rodriguez de Cordoba,S.,
            Rodriguez-Pena,J.M., Ronning,C.M., Rutter,S., Salzberg,S.L.,
            Sanchez,M., Sanchez-Ferrero,J.C., Saunders,D., Seeger,K.,
            Squares,R., Squares,S., Takeuchi,M., Tekaia,F., Turner,G., Vazquez
            de Aldana,C.R., Weidman,J., White,O., Woodward,J., Yu,J.H.,
            Fraser,C., Galagan,J.E., Asai,K., Machida,M., Hall,N., Barrell,B.
            and Denning,D.W.
  TITLE     Genomic sequence of the pathogenic and allergenic filamentous fungus
            Aspergillus fumigatus
  JOURNAL   Nature 438 (7071), 1151-1156 (2005)
   PUBMED   16372009
  REMARK    Erratum:[Nature. 2006 Jan 26;439(7075):502. Lafton, Anne [corrected
            to Lafon, Anne]]
REFERENCE   2  (bases 1 to 3948441)
  AUTHORS   Nierman,W., Wortman,J., Pain,A., Anderson,M.J., Arroya,J., Hall,N.,
            Barrell,B., Fraser,C. and Denning,D.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-MAY-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.2
            Run date    :: 2025-07-23 12:25:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 3882535
            Orig. end   :: 3915493
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..32958
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..32958
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32958
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[15000:17958](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="15000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..17958
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="15000"
                     /product="terpene"
                     /protocluster_number="1"
     mRNA            complement(join(<1394..1647,1703..2045,2094..2198,
                     2261..>2458))
                     /locus_tag="AFUA_5G15020"
                     /note="transcript AFUA_5G15020A"
                     /old_locus_tag="Afu5g15020"
                     /product="arsenic methyltransferase Cyt19, putative"
     gene            complement(<1394..>2458)
                     /locus_tag="AFUA_5G15020"
                     /old_locus_tag="Afu5g15020"
     CDS             complement(join(1394..1647,1703..2045,2094..2198,
                     2261..2458))
                     /EC_number="2.1.1.137"
                     /NRPS_PKS="Domain: oMT (63-217). E-value: 3.2e-15. Score:
                     47.0. Matches aSDomain: nrpspksdomains_AFUA_5G15020_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_5G15020"
                     /note="encoded by transcript AFUA_5G15020A; similar to
                     S-adenosylmethionine:arsenic (III) methyltransferase Cyt19
                     (GI:15488645) [Mus musculus]; GO_component: GO:0005737 -
                     cytoplasm; GO_function: GO:0008757 -
                     S-adenosylmethionine-dependent methyltransferase activity;
                     GO_process: GO:0046685 - response to arsenic"
                     /old_locus_tag="Afu5g15020"
                     /product="arsenic methyltransferase Cyt19, putative"
                     /protein_id="EAL91117.1"
                     /sec_met_domain="PCMT (E-value: 3.2e-08, bitscore: 29.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAEDTYQQVQSHYGDIARRTRVTVHDKEDEIALAFGYNAKDLRAL
                     PDKANLGLSCGNPVAYGNIKQGETIVDLGSGGGIDVLLAARKVGPEGNAIGIDMTKDMI
                     DLAKRNAEAAGLSNTRFIEASITSIPLPDASVDCIISNCVINLIPSRDKPSVFQEIARL
                     LKPGGRLAISDILARKELPPKIVNDIALHVGCIAGASQVAEYEEYLKRAGFKEILMVDT
                     KADLNLYKQSSYLGQSSCCGPAEPRKEWPTEFAELDFNEWVGKFHPSQYWLNEALMICV
                     ASFQIYAVKHSAVEQAMS"
     aSDomain        complement(join(1643..1647,1703..2045,2094..2198,
                     2261..2269))
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_5G15020_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.20E-15"
                     /label="AFUA_5G15020_oMT.1"
                     /locus_tag="AFUA_5G15020"
                     /protein_end="217"
                     /protein_start="63"
                     /score="47.0"
                     /tool="antismash"
                     /translation="IKQGETIVDLGSGGGIDVLLAARKVGPEGNAIGIDMTKDMIDLAK
                     RNAEAAGLSNTRFIEASITSIPLPDASVDCIISNCVINLIPSRDKPSVFQEIARLLKPG
                     GRLAISDILARKELPPKIVNDIALHVGCIAGASQVAEYEEYLKRAGFKEI"
     PFAM_domain     complement(join(1710..2045,2094..2198,2261..2266))
                     /aSDomain="Methyltransf_31"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13847.9"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15020_0171"
                     /evalue="7.00E-28"
                     /label="AFUA_5G15020"
                     /locus_tag="AFUA_5G15020"
                     /protein_end="213"
                     /protein_start="64"
                     /score="97.5"
                     /tool="antismash"
                     /translation="KQGETIVDLGSGGGIDVLLAARKVGPEGNAIGIDMTKDMIDLAKR
                     NAEAAGLSNTRFIEASITSIPLPDASVDCIISNCVINLIPSRDKPSVFQEIARLLKPGG
                     RLAISDILARKELPPKIVNDIALHVGCIAGASQVAEYEEYLKRAG"
     mRNA            complement(join(<4752..5141,5213..>5695))
                     /locus_tag="AFUA_5G15030"
                     /note="transcript AFUA_5G15030A"
                     /old_locus_tag="Afu5g15030"
                     /product="arsenic resistance protein ArsH"
     gene            complement(<4752..>5695)
                     /locus_tag="AFUA_5G15030"
                     /old_locus_tag="Afu5g15030"
     CDS             complement(join(4752..5141,5213..5695))
                     /EC_number="1.5.1.-"
                     /codon_start=1
                     /locus_tag="AFUA_5G15030"
                     /note="encoded by transcript AFUA_5G15030A; similar to arsH
                     (GI:32470162) [Salmonella typhimurium] contains an FMN_red
                     domain; GO_process: GO:0046685 - response to arsenic"
                     /old_locus_tag="Afu5g15030"
                     /product="arsenic resistance protein ArsH"
                     /protein_id="EAL91116.1"
                     /transl_table=1
                     /translation="MAYPTVDKLVTNEFSRCDMTCGQRRAIERRSLAITEAEDDNDIRR
                     KYRPFIQGGTQDDWVSTLELTGVLDMAENDLRITNKRIKVLVLYGSLRRRSYSRLVALE
                     ACRILFRLGCDVRVFDPEGLPIKNDTDHTHPKVQELRELSTWSDGQVWVSPEQHGNLTA
                     VFKNQIDWIPLSTGSVRPTQGRTLAIAQVCGGSQSFNAVNSLRILGRWMRMFTIPNQSS
                     IPKAYTQFPEEGQPADLRLIPSSNRDRLVDCMEELVKYTILMRPHMALFGDRFSEREEK
                     KAIETRRTL"
     aSDomain        complement(join(4785..5141,5213..5461))
                     /aSDomain="TIGR02690"
                     /aSTool="tigrfam"
                     /description="resist_ArsH: arsenical resistance protein
                     ArsH"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_5G15030_0015"
                     /evalue="1.30E-97"
                     /identifier="TIGR02690"
                     /label="AFUA_5G15030"
                     /locus_tag="AFUA_5G15030"
                     /protein_end="280"
                     /protein_start="78"
                     /score="323.1"
                     /tool="antismash"
                     /translation="TNKRIKVLVLYGSLRRRSYSRLVALEACRILFRLGCDVRVFDPEG
                     LPIKNDTDHTHPKVQELRELSTWSDGQVWVSPEQHGNLTAVFKNQIDWIPLSTGSVRPT
                     QGRTLAIAQVCGGSQSFNAVNSLRILGRWMRMFTIPNQSSIPKAYTQFPEEGQPADLRL
                     IPSSNRDRLVDCMEELVKYTILMRPHMALFGDRFSEREE"
     PFAM_domain     complement(join(4947..5141,5213..5449))
                     /aSDomain="FMN_red"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03358.18"
                     /db_xref="GO:0016491"
                     /description="NADPH-dependent FMN reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15030_0172"
                     /evalue="8.40E-25"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="AFUA_5G15030"
                     /locus_tag="AFUA_5G15030"
                     /protein_end="226"
                     /protein_start="82"
                     /score="87.4"
                     /tool="antismash"
                     /translation="IKVLVLYGSLRRRSYSRLVALEACRILFRLGCDVRVFDPEGLPIK
                     NDTDHTHPKVQELRELSTWSDGQVWVSPEQHGNLTAVFKNQIDWIPLSTGSVRPTQGRT
                     LAIAQVCGGSQSFNAVNSLRILGRWMRMFTIPNQSSIPKA"
     mRNA            complement(join(<9803..10588,10697..11064,11138..11493,
                     11566..11999,12053..12260,12322..>12500))
                     /locus_tag="AFUA_5G15040"
                     /note="transcript AFUA_5G15040A"
                     /old_locus_tag="Afu5g15040"
                     /product="conserved hypothetical protein"
     gene            complement(<9803..>12500)
                     /locus_tag="AFUA_5G15040"
                     /old_locus_tag="Afu5g15040"
     CDS             complement(join(9803..10588,10697..11064,11138..11493,
                     11566..11999,12053..12260,12322..12500))
                     /codon_start=1
                     /locus_tag="AFUA_5G15040"
                     /note="encoded by transcript AFUA_5G15040A"
                     /old_locus_tag="Afu5g15040"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL91115.2"
                     /transl_table=1
                     /translation="MSPPPLPPADPNEHQYWTDPILCEETRARLEHFRSIGWLPPNFKP
                     KTLEGLAVVERYWRRFCIHSKEDYVEYLLLEDQTIYMNFFDWMYRTSRQKLLQSYDEYW
                     RRLCQYFGLFARRRLNGNVYEQMRRFLNKVFPAERKIPRRMKKKDTLDVNVFCILYRQH
                     WIYSRFFRHGSMIIQFAVVQLWSAITGTRPGVLLPQKASQTGHKSSLGKRKREQTFQSD
                     LPKHVSADDLPDSVCYRDIELFILKDPDSKRDVLCAIIEFRNLKGRPEGADGTKFFMHG
                     DYQMAYCPINQIISLAFRDGAFVNPLTPELIWRLRVPKRRQDLPLRWKEEILDTPLLRR
                     IERTPHGYELHKSLPMTYDSSRQALKELGRDAKFEDDIGHYNYRRWVANEVNRNFTSQE
                     RQRVLGQSGDAVFERHYQSQFIGRDLQHVVLLRPSQEGLLRVAGSMLRKRDPLAPSGLT
                     DQQKRAICRDPRILELRREQRELKEEMRSLAGTVAKARESFPHLHERHEAVKKELSQSD
                     AESCEDLDSDDEDWDIPIPEYVFPERARLVENFYGPEAECFDADKLLARRIQVTKDMVA
                     LSKLCEPSRRGNQINWDVSDGAKADETEREESEESPPSEEEALDCPTDVCIICCGLSRR
                     SASNPPPHKFPSKRKDSLRRHLIDFHLARAHEGISCTWSACCNVPKFAKATEFLAHAVD
                     VHSYDIGIKLKHLPSRPLLTCSDTSSIDSTDASLESCGRSGTSTPASSVGSVTTNIDPR
                     LLELDKGTVTEPPPRRSKRVRLQ"
     PFAM_domain     complement(10403..10576)
                     /aSDomain="DUF3435"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11917.11"
                     /description="Protein of unknown function (DUF3435)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15040_0174"
                     /evalue="4.00E-06"
                     /label="AFUA_5G15040"
                     /locus_tag="AFUA_5G15040"
                     /protein_end="577"
                     /protein_start="519"
                     /score="26.2"
                     /tool="antismash"
                     /translation="SCEDLDSDDEDWDIPIPEYVFPERARLVENFYGPEAECFDADKLL
                     ARRIQVTKDMVAL"
     PFAM_domain     complement(join(10580..10588,10697..11064,11138..11493,
                     11566..11834))
                     /aSDomain="DUF3435"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11917.11"
                     /description="Protein of unknown function (DUF3435)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15040_0173"
                     /evalue="1.30E-97"
                     /label="AFUA_5G15040"
                     /locus_tag="AFUA_5G15040"
                     /protein_end="518"
                     /protein_start="184"
                     /score="327.5"
                     /tool="antismash"
                     /translation="WSAITGTRPGVLLPQKASQTGHKSSLGKRKREQTFQSDLPKHVSA
                     DDLPDSVCYRDIELFILKDPDSKRDVLCAIIEFRNLKGRPEGADGTKFFMHGDYQMAYC
                     PINQIISLAFRDGAFVNPLTPELIWRLRVPKRRQDLPLRWKEEILDTPLLRRIERTPHG
                     YELHKSLPMTYDSSRQALKELGRDAKFEDDIGHYNYRRWVANEVNRNFTSQERQRVLGQ
                     SGDAVFERHYQSQFIGRDLQHVVLLRPSQEGLLRVAGSMLRKRDPLAPSGLTDQQKRAI
                     CRDPRILELRREQRELKEEMRSLAGTVAKARESFPHLHERHEAVKKELSQSDA"
     mRNA            complement(join(<12947..13698,13748..>13988))
                     /locus_tag="AFUA_5G15050"
                     /note="transcript AFUA_5G15050A"
                     /old_locus_tag="Afu5g15050"
                     /product="cytochrome P450 oxygenase, putative"
     gene            complement(<12947..>13988)
                     /locus_tag="AFUA_5G15050"
                     /old_locus_tag="Afu5g15050"
     CDS             complement(join(12947..13698,13748..13988))
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_5G15050"
                     /note="encoded by transcript AFUA_5G15050A; similar to
                     SP:Q12612: trichodiene oxygenase, cytochrome P450 58
                     [Fusarium sporotrichioides]"
                     /old_locus_tag="Afu5g15050"
                     /product="cytochrome P450 oxygenase, putative"
                     /protein_id="EAL91114.2"
                     /sec_met_domain="p450 (E-value: 4.2e-20, bitscore: 68.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDFMSPAAILTFVKEQFAMFIILLLIFSLILRSFYRLYLHPLRHI
                     PGPKLAAISHAYEFYHDVIRGGLFVWEIEKMHKKYGPIVRINPREVHIKDPYFYDELYA
                     PISGMRDKDPKSVVIFSAPTSLVATVGHQTHRMRRKLLNNFFSRRSIENIEPVIHNSLS
                     RFLDGLTTAYKEGSVVELIDRLQGLTGDVITEYAYGENYGLQDPENYGKGIVKVVQEGT
                     DQIHFFRFFPLVSQLLRIIPSWFMGQVFPARAAIYQLLDGVRKQSILALQQKNVSTAPQ
                     RMTIFQALTAPEVPPEERNLQRLQDEGLVLFAAGTETTATTLAVALFYN"
     PFAM_domain     complement(join(12956..13698,13748..13775))
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15050_0175"
                     /evalue="6.10E-19"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_5G15050"
                     /locus_tag="AFUA_5G15050"
                     /protein_end="328"
                     /protein_start="71"
                     /score="68.2"
                     /tool="antismash"
                     /translation="EIEKMHKKYGPIVRINPREVHIKDPYFYDELYAPISGMRDKDPKS
                     VVIFSAPTSLVATVGHQTHRMRRKLLNNFFSRRSIENIEPVIHNSLSRFLDGLTTAYKE
                     GSVVELIDRLQGLTGDVITEYAYGENYGLQDPENYGKGIVKVVQEGTDQIHFFRFFPLV
                     SQLLRIIPSWFMGQVFPARAAIYQLLDGVRKQSILALQQKNVSTAPQRMTIFQALTAPE
                     VPPEERNLQRLQDEGLVLFAAGTETTATTLAVALF"
     mRNA            join(<15001..15807,15856..15961,16015..16301,16357..>17958)
                     /locus_tag="AFUA_5G15060"
                     /note="transcript AFUA_5G15060A"
                     /old_locus_tag="Afu5g15060"
                     /product="terpene synthase family protein"
     gene            <15001..>17958
                     /locus_tag="AFUA_5G15060"
                     /old_locus_tag="Afu5g15060"
     CDS             join(15001..15807,15856..15961,16015..16301,16357..17958)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_5G15060"
                     /note="encoded by transcript AFUA_5G15060A; contains
                     terpene synthase domain"
                     /old_locus_tag="Afu5g15060"
                     /product="terpene synthase family protein"
                     /protein_id="EAL91113.1"
                     /sec_met_domain="T2TS (E-value: 9.8e-110, bitscore: 363.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MIGNPGALLVDMKKQGLFESFDKSYHPTYGIGTMSGNIYDTSWIS
                     MVRKPTEGGSVWAFPAAFQAILQEQSPCGSWGGSTSELDCIVSTLAALLSLQKHAGDCC
                     ETEFEDLHSRILKAKQFLQTALKGLDRLLATCTLSVGLEVRLPEILDLLELEGHTFNFD
                     RTYLTEIQSKKLSKINLETIFNGPQSSLLHSLEAVIRKVDIKALGHQKVLGSMLASPSA
                     TAAYLMYSPVWDDEAEEYIRHAISKGAGRGSGLVAAGYPTTVFEWAWVTSNLLRHGFET
                     SSHLIQIGSQVEDEIRKQGLVGFVPNACADADDTAKALVALMLQGTRYSPQALVDRFER
                     ENHFATYLYETHTSVSTNSNVLAALVLLSTDGHYQPQIEKCIRYLCEAWFNCNGMLKDK
                     WNISPYYPTMLMCEALMSYIQRWSEGYLAALPDDVMRFQLPLTLFQSLIRTLHTQNRDG
                     SWGCSNSAEETAYAILILKSAACFSFTELIAACVKTAISKGLEFILARSQRSPTDDQLW
                     LDKTLYAIPTVSDSYIMAAVQAEETIQKLAEIPYKLVDMSTIMANKMTNYFSQLPSQMQ
                     TPKWVIQASAIEAILLSEKLKALDVFSTGRPLGEKYIKIAACFWTLASNSTPGCLLSTR
                     TIYSMAELSIGLFQEDDLMERSLASLPDTAIPIITDYIDKLCHATNLCKDHSLHQCLDG
                     DNTPGMDEEALTMVKVIQQNIERWFRFVLGEDFTRNASSSDRLDLEQEVKLATLAATQR
                     ARENRALSNSSGNSHTEHVTLRSGQNFYTWLHTSAVHDVKSAVVSKALICTIGNGNDVF
                     VTAKEKYLAERLWGQMSVEGRLWNDVGSIERDRLTKNLNSVNFPEFSSPQSLNSDGDVR
                     TQLIQLAEYEHKHTLSCLNDLTQILENSGRQTISLYLQMYHRCCIIYNETCAKYAFGST
                     TAM"
     mRNA            complement(join(<18686..19025,19098..19325,19374..>19423))
                     /locus_tag="AFUA_5G15070"
                     /note="transcript AFUA_5G15070A"
                     /old_locus_tag="Afu5g15070"
                     /product="AhpC/TSA family thioredoxin peroxidase, putative"
     gene            complement(<18686..>19423)
                     /locus_tag="AFUA_5G15070"
                     /old_locus_tag="Afu5g15070"
     CDS             complement(join(18686..19025,19098..19325,19374..19423))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_5G15070"
                     /note="encoded by transcript AFUA_5G15070A; similar to
                     thiol-specific antioxidant TSA1 (GI:14161441) [Ajellomyces
                     capsulatus]; GO_component: GO:0005739 - mitochondrion;
                     GO_function: GO:0008379 - thioredoxin peroxidase activity;
                     GO_function: GO:0016209 - antioxidant activity; GO_process:
                     GO:0006979 - response to oxidative stress; GO_process:
                     GO:0030503 - regulation of cell redox homeostasis"
                     /old_locus_tag="Afu5g15070"
                     /product="AhpC/TSA family thioredoxin peroxidase, putative"
                     /protein_id="EAL91112.2"
                     /transl_table=1
                     /translation="MGHMLFKSLASNQRNHKYMKSGRLHPVCTTELADLAKHQSEFAKR
                     GVKLIGLSANSIESHDGWINDITEIAGCSLTFLVIGDEDRKIAHTYDMLDHQDVTNVGA
                     RGIAYTIRSVFIIDPNKVIRLIQAYPASTGRSTTELLRVVDSLLVTDKYSVNTPANWEP
                     GDDVVVPAGLTAEEAQVKYPNMETVKPYLRFIPLARHHLYQH"
     PFAM_domain     complement(18755..18865)
                     /aSDomain="1-cysPrx_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF10417.12"
                     /db_xref="GO:0051920"
                     /description="C-terminal domain of 1-Cys peroxiredoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15070_0177"
                     /evalue="1.00E-08"
                     /gene_ontologies="GO:0051920: peroxiredoxin activity"
                     /label="AFUA_5G15070"
                     /locus_tag="AFUA_5G15070"
                     /protein_end="183"
                     /protein_start="146"
                     /score="35.0"
                     /tool="antismash"
                     /translation="LLVTDKYSVNTPANWEPGDDVVVPAGLTAEEAQVKYP"
     PFAM_domain     complement(join(18929..19025,19098..19300))
                     /aSDomain="AhpC-TSA"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00578.24"
                     /db_xref="GO:0016209"
                     /db_xref="GO:0016491"
                     /description="AhpC/TSA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_5G15070_0176"
                     /evalue="1.30E-19"
                     /gene_ontologies="GO:0016209: antioxidant activity"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="AFUA_5G15070"
                     /locus_tag="AFUA_5G15070"
                     /protein_end="125"
                     /protein_start="25"
                     /score="70.5"
                     /tool="antismash"
                     /translation="PVCTTELADLAKHQSEFAKRGVKLIGLSANSIESHDGWINDITEI
                     AGCSLTFLVIGDEDRKIAHTYDMLDHQDVTNVGARGIAYTIRSVFIIDPNKVIRL"
     repeat_region   complement(21842..21884)
                     /rpt_type=tandem
                     /rpt_unit_seq="acagcagtcctaattta"
                     /satellite="microsatellite"
     repeat_region   complement(22312..22428)
                     /rpt_type=tandem
                     /rpt_unit_seq="tttttcctttta"
                     /satellite="microsatellite"
     repeat_region   complement(22317..22429)
                     /rpt_type=tandem
                     /rpt_unit_seq="cttttt"
                     /satellite="microsatellite"
     repeat_region   complement(22761..22844)
                     /rpt_type=tandem
                     /rpt_unit_seq="cttcgatcgcgcgggcaaggtgagcataggaatatataaagcg
                     "
                     /satellite="microsatellite"
     repeat_region   complement(22943..22974)
                     /rpt_type=tandem
                     /rpt_unit_seq="gatcacccgct"
                     /satellite="microsatellite"
     mRNA            complement(<24291..>24593)
                     /locus_tag="AFUA_5G15080"
                     /note="transcript AFUA_5G15080A"
                     /old_locus_tag="Afu5g15080"
                     /product="Rho-associated protein kinase, putative"
     gene            complement(<24291..>24593)
                     /locus_tag="AFUA_5G15080"
                     /old_locus_tag="Afu5g15080"
     CDS             complement(24291..24593)
                     /codon_start=1
                     /locus_tag="AFUA_5G15080"
                     /note="encoded by transcript AFUA_5G15080A; similar to
                     GB:BAA13968.1: Rho-kinase alpha [Sus scrofa]"
                     /old_locus_tag="Afu5g15080"
                     /product="Rho-associated protein kinase, putative"
                     /protein_id="EAL91111.1"
                     /transl_table=1
                     /translation="MELCSAVSWLESLGRVHGDIRPPNLLLDAEDHLKLADFDSVASVG
                     EPYAGAAPPWARLLGSEAGSENGTFGMCGARTEQFAIGSIIYSMKGGMSLMSSKL"
     repeat_region   complement(26189..26316)
                     /rpt_type=tandem
                     /rpt_unit_seq="agtttatct"
                     /satellite="microsatellite"
     repeat_region   complement(26210..26314)
                     /rpt_type=tandem
                     /rpt_unit_seq="tttgtctagtttatccta"
                     /satellite="microsatellite"
     mobile_element  28703..30193
                     /mobile_element_type="transposon:gypsy transposon family"
     repeat_region   complement(30291..30492)
                     /rpt_type=tandem
                     /rpt_unit_seq="tctggttgg"
                     /satellite="microsatellite"
     repeat_region   complement(30325..30484)
                     /rpt_type=tandem
                     /rpt_unit_seq="gtctg"
                     /satellite="microsatellite"
     mobile_element  30626..31354
                     /mobile_element_type="transposon:gypsy transposon family"
     repeat_region   complement(32526..32564)
                     /rpt_type=tandem
                     /rpt_unit_seq="ttta"
                     /satellite="microsatellite"
ORIGIN
        1 aagcaatctg ccttcaagaa tctcgggata cttgataggt tccttgcgtt gtggattttc
       61 ctggcgatgg caattggaat cattcttggc aactttgtac ctaacactgg gcctgcgttg
      121 caaaagggca aatttgtagg ggtctctgtt ccaattggtg agtactgctg gtaacagacc
      181 gtgccctctc acactactaa attctccctc ggcagctatc ggccttctcg tcatgatgta
      241 ccctattctg tgcaaggttc gatatgaggg cctgcatcat gtttttcgga cgcgtcagat
      301 ttggatacag atcgccttca gcatattcgt caattggatt atagcgccgt tcttcatggt
      361 aggttgatcc ttgattgtgc cccccataga ctcgactgac gtgcaatcct atccagttgg
      421 cattggcttg ggcgttcctg cctgatgagc cggagctgcg gcaggggctg attcttgtag
      481 gactggctcg ttgtattgct atggtagaca tttccaagcg gccctatcct cctgcttatt
      541 cgtacttatg ttgtcactag gtcttaatct ggacaggatt agcaggaggg gacggtgaat
      601 actgtgctat cctcgttgct gtcaactcga tcctccaaat ggttctattc gcccctatgg
      661 gggtcttttt tattcaagtt atcagcggcg attccgtcgc atttgaatac tctactgccg
      721 cgaaaagtgt cgctgtgttt ctcgggatcc ccctaggcgc cgcaatcctc acgcgcttca
      781 ccctccggtg ggttgcaagc ccaaaatggt atgatgaagt ctttctgaaa tgggccagcc
      841 catggtcatt gatcgggctc ttgttcacca tcctggtcct gttcgcttct caaggacgcc
      901 aagtggtgca tcagattgtc tctgttgtcc gggttgcggc ccctcttatt gtttacttca
      961 ccgtcgtgtt cttcgtgact ctcttcatct catataagat gggtttcggg tataagctgt
     1021 cggcgacaca aagttttact gcagccagca acaactttga gctggctatc gctgttgctg
     1081 ttgcgacatt tggagcgaac agcaaccagg cccttgcgtc cacagtgggg ccattaattg
     1141 aggtgccggt gctgctaggg cttgtctacg ctgtgaaagc tctggcaaag cggctagctt
     1201 ggaaagatta gatccgataa acgatagata tggcttgcca tagctagggg aatacttcaa
     1261 atacacttga aaattcagga taactagaat gagaggggaa gactagataa tcaacttgaa
     1321 tggcgccgct atcaaataca ttaattcttc attgtgagaa ctacatcagg agtaaacctc
     1381 agacactagt actctaagac atggcctgct cgacggcgct atgtttgaca gcataaatct
     1441 gaaaagaggc tacacagatc attaatgcct catttaacca gtattggctc ggatgaaact
     1501 taccaaccca ttcattgaag tccagctcag caaactcagt gggccactct ttgcggggct
     1561 ccgctgggcc acagcagcta ctttgaccca gataggagga ctgtttatag agattgaggt
     1621 ctgctttagt atcgaccatc agaatctctg aaggcatgtc agtagcgaag aagcaacatc
     1681 tgtgtgtaaa ctaagtacgt acctttgaat cctgcgcgtt tgagatattc ttcgtactcc
     1741 gcgacctggc tggcccctgc aatgcaccct acatggagag cgatatcatt gacgattttc
     1801 ggtgggagct ccttccttgc cagaatgtca ctgatagcaa gccttccgcc cggcttcagc
     1861 aagcgagcaa tttcctggaa tacagagggt ttatctcttg atgggataag attgatgaca
     1921 cagttgctga taatacagtc aacgctggca tctggaagcg ggattgaggt gatggacgcc
     1981 tcaataaacc gcgtatttga caggccagcc gcttcggcgt ttcttttcgc gagatcaatc
     2041 atatcctggt cgaggtatta gtatatagct cctcaagggc cagagttgtt aaccttcgtc
     2101 atgtcaattc caatggcatt tccttctggt cccaccttgc gagctgcaag aagaacatcg
     2161 atgccgcctc cacttccaag gtcaacaatt gtctctccct agctcaattg tcaaagcgtt
     2221 aggacgtgtg agtctatggc cacatatcga gatcaggtac ctgcttgata ttgccatatg
     2281 ccactggatt gccacaactc aatcctaggt ttgccttgtc tggaagggca cgtagatctt
     2341 tcgcgttgta cccaaacgcc aatgcgattt cgtcttcctt gtcatgaact gtgacgcgag
     2401 tgcgtctggc gatatcccca tagtgagact gcacctgttg ataggtatcc tcagccattt
     2461 taatagcctg gtgtgcggac gattgtttgg caacttcaat gttcctcgac ggtggaggtg
     2521 aagcagaaag gaaagagaca gggcgacctt taacacagag acagacttca accaaactat
     2581 gcaagtgtag agcgaacagg tggagggtgt tagtctgtat ttatgtcctc aagccgagtg
     2641 tacggctgcc taagtcaaag agtcctgtac attataagtg tcaccgctac cttggcggtg
     2701 attggccagc cgtataactg gtatgtcacc actatacccc tcaaagcatc aaccagcaaa
     2761 gacgacactg atatgtcacc ggtttcgtat ataatcctat tgtttttgca atatcatttg
     2821 gtcagtctgg tatgattggc catcttctgt caatgatcct tggaggataa aatacggaag
     2881 acagacaaat ccattagcgc caataattga tgggaataac ggcagcagct gtcatcgtgt
     2941 accgttaatt atgaacagat gagcaaagga aaaaatgaga ctattgtata atttcggcaa
     3001 ggaccgtcag caaaacccag ttattgaccc tacaaccttc cagaggagac cttggtggcc
     3061 tatacccgtg acggagttta gtatccacct ccagcatgct tagatccttc ttattacagt
     3121 gaaagacaag ctgaatggca acagcacaaa ctgttgtgtc ttgtagaata ggattaacta
     3181 atcccatggt gatatcgccc ctggttgtac tttggttatc cagaggcagg tgctcgagca
     3241 aacgggtttg tgattgtctc tccagtacag tcggatcata gaaatttggt atcggatagt
     3301 ccagccaagt attaagatct gtagattgcg agggcgtaaa atctacaatc gaaggcgccg
     3361 caggcccggt atctgcaact tcaggtatcg tagcgggaaa tccaaagcta agagtaacct
     3421 gacataggtc agtcatgact tcaacgagcg gtaccgaaca cctctggtgc aggtagtgga
     3481 tagtcatacg tttggcaact gcagggctgt cgagccagcg tgcagttcag gggtggtcgg
     3541 cactgtattt gccgcaatgc tgagactggt ttgtatctca ttggacgtaa cttcttgacg
     3601 ctcctcggcg gtatcctgtc cccggacatc acgaccgggg ccactggacg ctaacagggc
     3661 ccgcagtgcc tcgttttctc tgcggaggtt ctccatcgtg gcctgccatc tcctatctga
     3721 ctgagccgca gcctccgcgt aagatgtgat tttgctttct agttcggcca cgtagtcacg
     3781 ctgtcgttgg cgacatttgc gctggttgtc ccggatccgc ttgaggtcct catcctagta
     3841 tgagtgtcag atgctgtgat ggatagagaa tgtgttgagt gtccttgcct tggtcttctg
     3901 ttttacgcgt ggcatgtttg actgtggatt aagggccaac cgggaggttt cagtagaact
     3961 agatggctaa cagctgcggc cgatgcttgg aacagtggtt gtgcgggata ttaatgtgcc
     4021 tggcatgtaa gtccgtctgc ccatgtctga tcaatgtcac aatgatctcc tgtgccagac
     4081 gaaaacgcgg ggattcacgt aaggaaccac tttacttatt gctcaccatc gaataggagc
     4141 gatgtgatga cataccattg cgcttggcgt actattacta agcagttttg gcaatagggt
     4201 agttaactag gttaagttag tcactccgca gttaacttgg ttctgtgact accaaacatc
     4261 ttttccccgt gtacagcaag ccaaggggga gaaaagtgaa aaatgacaac agattcctag
     4321 gtaagtatag agtaggccga ggtatatgtc taaggaaagg taaattggaa tctaagaaca
     4381 gagaaaagtt cagaaatctt cagcagtatg tgggccctta ttactagcag aaaagccgga
     4441 ggctatcttt gcttttcttc ttcggacctc ccccaacttg tgccccgatg acagcaccag
     4501 acagaaaaca ttgcatatat ggagcgtgga aatgggactt ttcggaaatt ttggtcaata
     4561 aagcatttgc gtatctagag aagagcgaaa cacccgggaa aaagacgaaa aaatgggaca
     4621 cggctgttac agtaaccgcg ccgttatggt tcggtctcct ttgccattat acaaggcatg
     4681 atggcccctt ttgcctgcag cgggtaactc cctaaaagta tgtacatgcc accttgatca
     4741 catgtagatg gttataaagt tcttcttgtc tcgatcgctt ttttctcctc ccgttcgcta
     4801 aaacggtcac cgaaaagggc catgtgaggg cgcatcagga ttgtatactt gactaactcc
     4861 tccatacagt ctaccagacg gtcccggtta ctactgggga tgagtctcag gtccgccggt
     4921 tgaccttctt ccggaaactg ggtgtatgcc ttgggaattg aggactgatt tgggattgtg
     4981 aacatccgca tccagcggcc gaggatgcgc aaagaattga ccgcattgaa tgactgagaa
     5041 ccaccacaca cctgggcgat ggcaagtgtc cggccttgag tcggacgcac gcttccagta
     5101 ctgagaggta tccaatcgat ctgattctta aaaacggcgg tctgatttcc gaatgacatg
     5161 taagtaatac tgccatcact tttggcacga tcaggggaaa cacgaaacga accaggttgc
     5221 cgtgttgttc aggcgaaacc caaacttgtc catcactcca tgtgctcagc tcgcgaagct
     5281 cttgcacttt gggatgggta tgatcggtat cattctttat cggtaaccct tcgggatcga
     5341 agacccgcac atcgcagccc agcctgaaga ggattcggca agcttcaagt gccacgagcc
     5401 gtgagtacga ccttctgcgt aggctcccat atagtacgag aactttaatc ctcttatttg
     5461 taattcgcaa atcattctca gccatatcca ggacccctgt cagttccagg gtactaaccc
     5521 aatcgtcctg ggtgccgccc tgaatgaatg ggcggtactt tcggcgaata tcgttgtcat
     5581 cttcagcctc tgtgatagcg agagatcgcc tctctatggc ccgccgctgt ccacaagtca
     5641 tatcacatct ggaaaactcg tttgtaacta gcttgtcgac ggtagggtat gccatagttg
     5701 tataagtgtg tcgctacaat gatagcgtag agcaggttgc ttggctgact taactgttaa
     5761 cgatacttta tagaaagtat tcatttggaa ggctccggtc tatcaggatt aggcagctga
     5821 gaatgagcta gcatcgagat actgaagcat gacagcttat tccgtagttc aatggaagat
     5881 acaggatact taagggtgtc actgctaacc aatgattgga cagggtaggc tagataacta
     5941 ttggctctaa gtcagttcgg tcccactcct accagtcgtc agcatattgc agtccttccc
     6001 gaacggaata cttaccgctt tcatctctgg ataaactccc catggttcat gaagcatttt
     6061 atcaacgtaa cacgcctcag aacgggaacc agtgcattat accattcctt ttatcatgat
     6121 tttcccggtt cctcgctttt ggcaaacatg agcaataaga gaaccaaacg cacaaagcct
     6181 actgcaaatg ttagcgagtc tcagacgggt gccataccat tctatacgat ctctgataga
     6241 ctaaaattta cttcaggccg atcatatcac gtcttccgta cgagtccgcg aaaaccaacg
     6301 gcgctctcgc gctcgacgca aagaatacat acgtgatctt gagctacgag tgcgcaggtt
     6361 tgagagcctt ggagtagagg cgacacttga gattcaagca gcagggagga aggttgccac
     6421 agaaaatgcc ctcctttgga agttactcag gcaccatggg gttacacaag aagaaatttt
     6481 ggaatacatc aaagctcacg cagtgggata ccctccgtgc aatcaatatt ccactcccag
     6541 cccaacaact cgaggcgatc acctatggag actcggagtt tcacagccaa ctccatgtct
     6601 ccctgaaggt aacagttcct tgcaacagat gacagttagg aaggttgctc tacctccctt
     6661 gtcggattca cttgccaaaa gacagggtga tcttctccgc gaccaatctt ccagtgtgga
     6721 gcaaccgact gctcaaggca ttacgcttcc tggtgcttcc aaaattgagc agttaaatga
     6781 agggcaatat acaggccagt ctacgccatg cgagactgca gctagaatta tcatgaccat
     6841 gcgaggcagc ccagatattc gcgaagtgcg gtctgagctg gggtgtcatt cggagtccaa
     6901 ctgcatggtg aggaacatgg acatttttga ggtattagat aaatgaaggt ctaatcagta
     6961 gaccactatc atttctgctt gcataatgca ggaaaagtag gctgaagata attttgaacc
     7021 aatgcctatg cttgcaatcc gagcagacga attcatgttc caaaccaggc ttcttgggca
     7081 cttcggattg gtggtctcag gatgtctaga tccagggtgg taacgacgac cttatgtatt
     7141 tagcctcggc tttttgccta gtaaatggaa ggcggaaacg cagctgggga ctatgctaca
     7201 cctgtccagg tattcgatgg ggatgcggcg gcccacttac ttcctctcat acggcatctc
     7261 attgactgcg gagaagtttg gcaggagcca ctgcggcact aagtctcgct ctgcttcctt
     7321 ccatccaata gtctgtccta ctggcaagcc tgcggcgtag catcttaggc gctgaggaca
     7381 aggtatcttc agccgcaaca ggatgtctct gtaagtttcc aatcccatca agtgaaagcc
     7441 atataagagg tatccgatta cgtgagacgt ctcgttgggg tgaatacgtt ctagaacagc
     7501 tgtctcatac ccaatttaga aatgacagaa gtgcatgtca ccccagcctg taacctgagt
     7561 gctgggtgct gggtgctcca cggctgattg tggctgtgga aatgcttggc aggcacccat
     7621 gccactggtt ggtggactgc ggtagcactg tggcgctaag ctttcttcgg cttccccagc
     7681 catttcccac ccaatagtca ccagcctcag cgtaccccca actcgcacta ccgcgtaaaa
     7741 ggatggttgt cgactggccc tgtttcctca ttgacccact ccctctcacg cgctttatca
     7801 ccgccctcca acgagtaccc gaaagtatgg ctaccaagca aacaaagctc tatctgtcaa
     7861 gaagcctgcc cacgctcggg ggcgttctct gcttactgcc gaatgacttc gatgacgagg
     7921 tacgtaaaac tggatgcagc aaaaatgggt gtcaatgtca gggacgggct tcccaacggg
     7981 tgaccgatta tttgcacagc cttcgtagag acggcgattt gtatggctcc caggagaaca
     8041 ggaagactgg agacaggtat tgtggacaat ggaatgtcga atatactgca gccaacaatg
     8101 tcttccctgg ttaaatttgt aaggaaaagg tgactgtggg acacctcgca tatgcggaga
     8161 gacgaatcga ggacaatggt aggtactggc gtaaggatga aaatcatctc taaacgtgcc
     8221 gctgatgttg caagacgttt ccgttcatcg cgattggccg gtaaagaact atcgtctggc
     8281 ggctgaattt gcggagccat gctgctttgc ataccatctt aagtaggtcc tctgcttgga
     8341 caagtttgtt gtttctcatt ctcaccaccg aagtccagtg ctcacgagac agtttgccaa
     8401 gcatcacgtg acattaatca cctactattt actagtgcac ctcagtgtat ccacatgatc
     8461 gctgtggaac cagtaatgta ctggaaaaca gaaacaggaa acaagtcaat gtttactcaa
     8521 gctcttgaca tagtagcgta accgtttacc cttccacata tttcacttcc agcctgccct
     8581 gacaatggag aaagagcctt tgaaattgac ttcccctcca gtatcctaca gaggtatgct
     8641 caagctagag gaccaattta ggaatacatc atcatccact cgaacagaca tgcaattcaa
     8701 ctcacttgtt aatcctacaa attccaaggt tgctatccct cggattgcgc gcgcccagtc
     8761 aggaaacgca gcccgccgtg ctaagagagc atgtctggga tgcagacaaa aaaaggccaa
     8821 atgtgacggc cgccaaccat gtcatcaatg tgtccttttc gatgccgttt gcgagtacgc
     8881 cgaggggaac gaagacagaa tcaaaaggta ggttcttcaa cccggctgta ggcccctcga
     8941 ggaacaattt tcagacgcgt tttagaactt gaaggacaga ttgatgtgta cgaccagttg
     9001 ctgcggaggt tacgattcaa ggtagatgtt cacgaccgag aggtgatcga tagggttctc
     9061 agtcgggtag gcatatccct gcaatcatct tatgcaataa tgccctggct aatactatcc
     9121 atagttcaac ccttcctcgt tcctggacat gcgaggtacc ttggagcggg aaaaaccgat
     9181 ggccggagag caggtggcca gttccgaaac aatcggcgag caaacccgag cgggcgaatc
     9241 aacgttaata tggaacgctc aatcggtaaa aatcaggtat aagccccgtt ggcataggcg
     9301 gcataggctc acgtataatg tggctctcgt gcacattgtc caaacggcac cacgccatac
     9361 ataactgcta tgtttcagat accaatatat gacttcaaat tcttaccaag cgagcataac
     9421 gagctcttct catgtagctg ttattttgct cactgtggga ctggcaaaga ctctgtcaaa
     9481 tatttaacat ccatgggcta cagcggaaca actggtcaat caatataact aatattagcg
     9541 gcatggttgt ggctaaaata cggagaaacc agcatccgct ctccaggctt gtgaatcatg
     9601 tgacgtatgc ttatactgct aagtagggag taaattaaaa gcaaaacagg tgcattttgg
     9661 caggtacgag accagctata tacaatggta gacgccacta aatacaactc tgcatagaaa
     9721 aaaaaggaag ccgcaaagcc aggcttcagc ggatcattgt actcacattg taacgactgc
     9781 atctagacat cctcgcatgc tatcattgga gacgcaccct ctttgagcga cgcggcggtg
     9841 gctctgtaac ggtacctttg tcgagctcca gcaggcgcgg gtcgatattt gttgtcacag
     9901 agccgacaga ggaagcggga gtgctagtgc ctgaccgtcc acatgattcc agagaagcgt
     9961 ctgtgctgtc gatagaggaa gtatcgctgc aagttaacag aggtctgctg gggagatgtt
    10021 ttaatttgat tccaatatca tatgagtgca catcaacggc atgcgccaag aattcagtag
    10081 cctttgcgaa cttagggaca ttgcagcagg ccgaccaggt acagctaatc ccctcgtgcg
    10141 cacgggcgag atgaaaatca atgagatggc gacggagtga atcttttcgc ttggaaggaa
    10201 atttatgtgg aggcggatta gaagctgaac gacgtgacaa accgcaacag ataatgcaaa
    10261 catctgttgg gcagtccagg gcttcttctt cagaaggtgg tgattcttcc gactcttcac
    10321 gttcagtttc atcagcctta gcgccatcac tcacatccca gttgatttgg ttgcctcgcc
    10381 ggcttggttc gcagagcttc gagagcgcaa ccatgtcctt ggtaacctgg atacgtcgtg
    10441 caagtagctt atccgcatca aaacattccg cttcagggcc atagaaattc tccaccagtc
    10501 gcgctcgctc gggaaagacg tattctggaa taggaatatc ccagtcttca tcgtcggagt
    10561 cgagatcttc acaactttca gcatcagact ggccaagaag ttgcttgatc tgtctgtcaa
    10621 cttcgagcac aggctcattg tgaaaatatt cctttctagc tgtctcgcga gtatcctttg
    10681 tcaggttctt ccttacttga gagagctctt ttttaactgc ctcatgtctt tcatgcagat
    10741 gagggaatga ctcccgagct ttcgccactg taccagctag cgatcgcatc tcctccttta
    10801 gctccctctg ctctcgtcta agctcaagga ttctggggtc tcgacaaata gcacgtttct
    10861 gctggtcggt aagacctgac ggggcaaggg gatccctctt cctgagcatg cttccagcaa
    10921 cccgaagcag accttcctga gagggtcgga gaagcacgac atgctggaga tcgcggccga
    10981 taaactgtga ctggtaatgc ctctcgaaaa ccgcgtcgcc ggactggcct agcactctct
    11041 gccgctcctg gcttgtgaag ttccctgtaa ggtcaagtta gatacagttt caggttcttt
    11101 cgttttgcaa agccatcttc cacgcgggag gacatacgat taacttcatt ggcaacccag
    11161 cgccggtagt tataatggcc aatatcgtcc tcaaacttag catctcgacc tagttctttg
    11221 agcgcttgtc gacttgagtc gtacgtcatc ggcaatgact tatggagctc gtagccgtgc
    11281 ggagtgcgct caatacgtcg aaggagaggg gtatcaagga tctcctcctt ccaccggagg
    11341 ggaagatcct gtcggcgctt tggaactcga agccgccata tcagctctgg agtcaaggga
    11401 ttgacaaaag ccccatcgcg gaaagctagt gagataattt ggttgattgg gcagtaagcc
    11461 atttggtaat caccatgcat gaagaattta gttctgaggg aaaagaaagt tagcctcagc
    11521 aggtcagcaa ctagctgtct atggatctgc tatggatccg cttacccgtc agcgccttct
    11581 ggccggcctt tgaggttgcg aaactcaatg atggcacaaa ggacatcacg cttgctatcg
    11641 gggtctttaa gaatgaagag ctcaatatcg cggtagcaga ctgaatctgg aagatcgtcg
    11701 gccgaaacgt gtttgggaag gtcactctga aaagtctgct cgcgtttgcg tttgcccagg
    11761 gatgacttat ggccagtctg ggaagctttc tgaggaagca gtacacccgg tcgcgttcca
    11821 gtgatggcag accagagttg cactacggca aattggataa tcatactccc gtgacggaaa
    11881 aatctcgaat atatccagtg ctggcgatat aagatgcaga agacattaac gtcaagggtg
    11941 tccttcttct tcatacgtct ggggatcttt cgctctgcgg ggaatacttt attcaggaac
    12001 taacgccgat gttaatggtg gagctgctgg gaccaagaac gaaacaacgt actcgtcgca
    12061 tctgttcata gacgttgcca ttcagacggc gccgtgcaaa cagaccaaag tattggcaaa
    12121 gccgtcgcca gtactcatcg tacgactgaa gaagcttctg tcgtgaggtc ctgtacatcc
    12181 aatcgaagaa attcatgtag attgtttggt cctccaggag taaatactcc acgtagtcct
    12241 cttttgaatg gatgcaaaat ctgtcgacgg tacgttaagg acgtacgatc cctgcagcaa
    12301 tctgagaaag cgcgtacgta ccttcgccag tatctttcga ccactgcaag accttccaat
    12361 gtcttgggtt tgaagttcgg gggtagccat ccaatgctgc ggaaatgctc gagtctggct
    12421 cgagtctctt cacagaggat cgggtcggtc cagtattgat gctcattggg atcagcggga
    12481 gggagaggag gcggtgacat caagatgagc tgatccaaat ataagagaaa gctgattgtt
    12541 ttcggcagtg attcgagcag cgatcgcctg gcggattgat ttggcaggcg tcaaggtggg
    12601 aggaaggcgc gagagtgcga gggaggaaag aaaggagtga ggatggccgg cattttatag
    12661 agcacatggg caatctgctt gaattcgagg gagctggatc tggctgctga ggaggccatt
    12721 gtcggcgtca ctaatggtcg tgaattgaac cgagcgagtt ctcgctgagg attgtctcct
    12781 caggacggtg actaaaacaa tgcttggcgg gtgcagaata gtggtgtgta gcacgtgctt
    12841 gagtgctaaa gcggcggctc gcagagggaa aatacaggtg gaaatgcggc cgtttatggc
    12901 ctcagtagct gtcattttcg gcgtcgattt cacaggtccc catattctag ttgtaaaata
    12961 atgccacagc taaggtggtc gccgtggtct ctgtaccggc agcaaacaaa accagtccct
    13021 catcctggag gcgctgcaga tttctttcct cgggcggtac ctctggagcc gtaagagctt
    13081 ggaaaatggt catcctctgg ggagccgtgg aaacattctt ctgctgaagc gcgaggattg
    13141 attgcttccg tacgccatcc agcagctgat atattgccgc tcgggccggg aagacctgac
    13201 ccataaacca tgagggtata attcgcaaga gttgcgaaac aagagggaaa aacctaaaga
    13261 agtgaatctg gtccgtccct tcttggacaa ccttgacaat gcctttgcca tagttctcag
    13321 gatcttggag cccatagttc tctccatacg catattctgt tatcacatcg cctgtcaacc
    13381 cttgtagtct gtcgatcaac tctactacgc tgccttcttt gtaggctgta gtaagaccgt
    13441 ctaggaatct tgagagtgaa ttgtggataa ctggctcaat attctcaatt gaccgccttg
    13501 agaagaagtt atttagtaac ttccggcgca tgcgatgcgt ttgatgacca actgttgcga
    13561 ctaatgaggt gggcgcacta aagatcacta cagattttgg gtctttgtct cgcatcccgc
    13621 tgatcggcgc ataaagctca tcgtagaaat atggatcttt gatgtggact tctcgggggt
    13681 tgatccgcac aattggacct atataaccgt aaatacaatg taagactgat ttgtctttga
    13741 gtgctaccat attttttatg catcttttca atttcccaaa caaatagtcc tcctctgatc
    13801 acatcgtgat agaactcata ggcatgagaa attgccgcca actttgggcc tggtatatga
    13861 cggagagggt gaagatacag acgataaaaa ctgcgcaaaa tcaaactgaa tatgaggagt
    13921 agtatgataa acatggcgaa ttgctccttg acaaatgtca aaattgcggc aggagacata
    13981 aaatccatgt tgtcaggagt ggcgtggttt aggggatggg aaaagccgtg atgagaatca
    14041 aagaaagtca ggagtcttat gagtatcaca gcttaaggtg ctttcagtca aagctctcta
    14101 taattggccg gcgagctgcc ccatcgtgca gtaggccttc aaggtcagct aagctgtatc
    14161 ggagagagtg gcaagggccc aagtgggtat atatttcaat gggctatgag gtttcccttc
    14221 ttatcccctc ttgacctgca ggggggtggg aagttggcgc tacagtagga taaggatgca
    14281 tatgcgtcta agcaatagtg aaatatgaat atgatgtgtc acatttgggg tcagtccttg
    14341 gacctcccac gagatgcact ggaaaatatc agctgtgaga cacccttgtt gaatacaact
    14401 atgcatatcg ggattttcga aaactcattt atttcatcgc ctgactagcc taataaatgc
    14461 gcagtatagc agatcaaatt agaaggtgga tgattttatg gcatatcata ttcaaataat
    14521 ggattaatca atcgttatgc agatcaagca atgatgattg ggtgccagca accctacagt
    14581 gcttctcagg ttctccacat aatgggtatg cctcactatg gcactgacag aagttcagga
    14641 ttcgaagaaa tctctgatac aggtgttggt tactgcagta ccatgtacca aacagtcttt
    14701 tgctcatcgt ccagctgcat ccgctatgcg cgatacagga cactcacaca ggtgttctgt
    14761 cgttggggag gatagctgaa tctaagtatg cagggactag ctctttagca tagtatatcg
    14821 gtcaagagct gaggtggccc agtgacaggg tctgatgcct tcgaatccag tcgaagtaca
    14881 cccatacatt ttatttaagg caaagcctac gccagacatt tctgagctga ttaacagtat
    14941 catccattca accaaatttc catattttcc cccatactct agtattatcc atcactcaat
    15001 atgattggca atccaggagc gttacttgtc gatatgaaga aacaaggctt gtttgagagt
    15061 tttgataagt cttaccatcc aacctacgga ataggcacaa tgtctggcaa catatacgat
    15121 acatcgtgga tctcgatggt gagaaagccc acggaaggtg gatctgtctg ggcgttccca
    15181 gctgccttcc aggctatttt acaagagcaa agtccttgtg gcagttgggg tggaagtact
    15241 tcggaattgg actgtattgt aagcacctta gcggctcttc tttctctcca gaaacatgca
    15301 ggcgactgtt gtgaaacgga gtttgaagat ttgcactcaa gaatcctcaa agcaaaacaa
    15361 ttcctacaga cagcgttgaa aggcttggat cgcttgctgg caacttgtac gttgtctgtg
    15421 ggcctagaag ttcgattacc agaaattctg gatctcctgg aattggaagg gcatactttc
    15481 aactttgatc gaacatacct gactgagatt cagtcgaaga aactttcgaa aattaacctg
    15541 gaaacaatct tcaacggccc acaatcgtct cttttacact ctttggaagc tgtgataagg
    15601 aaggttgaca ttaaggccct gggacaccag aaagtgctcg gcagcatgtt agcatctcca
    15661 tctgccaccg cagcatatct catgtattct cctgtgtggg atgatgaggc tgaggaatac
    15721 attcggcatg caatctccaa gggtgcaggt cgagggtcag gtcttgtggc cgcaggatat
    15781 ccgaccactg tattcgaatg ggcatgggta ggtttgaaca tgttatggca atgacgattg
    15841 ttctaatcca aaaaggtgac atcgaatctg ctacggcatg ggtttgaaac aagcagccac
    15901 cttatacaaa ttggcagcca agttgaagat gaaattcgaa agcaagggct cgttggcttt
    15961 ggtataggac cttcaatcta aaatttggct cttctgttaa cctgtggtga acagttccca
    16021 atgcatgtgc tgatgccgat gacacagcca aggcgttagt agccctgatg ctgcaaggaa
    16081 cacgctactc gccccaggca ttagtcgatc ggtttgagcg agaaaaccat ttcgcaacct
    16141 atctgtacga gacgcataca agcgtaagta cgaattctaa tgtcctggct gctctggtat
    16201 tgctttcgac cgatggccac taccagccgc aaatcgaaaa atgcattcgc tacctgtgcg
    16261 aggcatggtt taactgtaac ggaatgctca aggataaatg ggtatgttga acgtttttcc
    16321 cagattatgt gtgctacatt ctaagggtat cgctagaata tctcacctta ctatccgacg
    16381 atgctcatgt gcgaagcctt gatgtcctac atccagcgct ggagtgaagg gtatctggcc
    16441 gcactaccag acgatgttat gaggttccaa ctaccgctca cgctctttca gtcattaatc
    16501 cgaacattgc acacccagaa cagggacggc tcatggggat gctcaaactc tgctgaagag
    16561 actgcatatg ccatcctgat tttgaaaagc gccgcatgtt tcagtttcac tgagctgata
    16621 gcagcctgtg tgaaaactgc aattagcaaa ggcctcgagt ttattttggc tcgaagccaa
    16681 cgctcgccga cagacgacca gctttggttg gataaaacct tgtatgccat accgactgtt
    16741 tcggactcct acatcatggc cgctgttcaa gctgaggaga ctattcaaaa acttgccgaa
    16801 ataccataca aactggttga catgtcaacg atcatggcta acaaaatgac caattacttt
    16861 tctcaattgc catcccaaat gcaaacgcca aagtgggtca tacaagcttc cgcaatcgaa
    16921 gcgattctcc ttagcgagaa gttgaaagcg ttggatgtgt tttccactgg ccggcccctc
    16981 ggagagaagt acatcaaaat tgccgcctgc ttctggacat tggctagcaa ctccaccccc
    17041 gggtgtctcc tgagtacgcg gactatttac agcatggcag agctctccat tggtttgttt
    17101 caagaagacg acttgatgga gaggtcgctc gcaagtctac cggacactgc catccccata
    17161 ataaccgact atatcgacaa gttgtgccat gcaaccaacc tttgcaaaga tcattctctg
    17221 caccaatgcc tggatggaga taatactcct ggtatggatg aggaggctct caccatggtc
    17281 aaagtaatac agcaaaatat agaacgctgg ttccgttttg tcttgggtga ggacttcact
    17341 aggaatgcga gctcttcgga taggctcgat ctggaacaag aagtgaagct ggcgactttg
    17401 gctgctaccc agcgagccag ggagaacaga gcactaagca acagcagtgg aaattcgcac
    17461 accgagcatg tcactctacg ctcaggccag aatttctata catggctgca tacatctgct
    17521 gttcatgacg tcaagagcgc ggtcgtgtct aaagccctta tctgtacgat tggaaacggg
    17581 aatgatgtct ttgtcaccgc caaagaaaaa tatcttgccg agaggttatg ggggcagatg
    17641 tctgtagaag gcagactttg gaatgatgtc ggcagtattg agcgagaccg ccttacaaag
    17701 aacctcaatt cagtcaactt ccctgaattc tcgtctcctc agagcctcaa ctcagatggc
    17761 gatgtgcgga cgcaattgat tcaacttgcg gagtatgaac acaaacacac tctctcatgc
    17821 ttgaatgatt tgacgcaaat cttggagaat tctggccgtc aaaccatctc cctctacctg
    17881 caaatgtacc accgttgttg tataatttac aatgaaacat gtgccaagta tgcttttggc
    17941 tctaccacag cgatgtgata tgcaggtatt ttttatgtca atgcactaaa agttttgaag
    18001 aacagctgtc aattgttaat ggctatatat tactatagat tatcagagct gtgttgttct
    18061 acatgtttaa ggttactcta aatagtcatg gctatgcata aagatatatc tacacactat
    18121 ctctgtcaaa tcttgagtgg tgcataatat taagcctgtt tcagcttatc caatatggaa
    18181 tacaaaatat ccaaatagtc aattatcaca gcattgaata agacagaaga tcgctggagt
    18241 gtggctatgt actactacta aaaagattgg cagttgaagt ataaagatag tgtggtcaat
    18301 gttgatctgc gttctccgta atcccgaggg tctattcgta acccacatgg ttggatcaaa
    18361 tagtgtggat tggcccaact gagcttaaat cacaaactct ggaacggaga cacaccaact
    18421 ccatcaaaag taactaattc agaagacgag tggttgagat ccttttacgt aggcagaatg
    18481 agtgctgaca ccgggaaaat taccttacgc cgctagctat agccttgagg caggcagagt
    18541 ttgagttatg gtactatgct atgaacgact ttttcacagc tgaagcctcg ccatctgttc
    18601 ctacgtacca gaattccctt tgtatcagtc caagtcatcg aggaaagaga aattcgacat
    18661 aacatcaacc gtgcaagaat gacacctaat gctgataaag atggtgcctg gccaatggta
    18721 tgaagcgcaa atacggcttc acagtttcca tatttggata cttgacctgc gcctcctcgg
    18781 cagtgagacc cgcgggaacg actacatcat caccaggctc ccagttggcg ggggtgttga
    18841 cggagtactt gtcggtgaca agcagggaat ccacgacacg gagcagctca gttgtgctgc
    18901 gaccggtaga ggccggatac gcctggatga ggcggatcac cttgttggga tcgatgataa
    18961 acacagaccg gatcgtgtag gcgatgccgc gggcgccgac gttggtgacg tcctggtggt
    19021 cgagcctgtt cctcgtcgca ctttgttagt gtcgagccaa cagtgggcgg cagacgaaaa
    19081 ggggagagat cccttacata tcataagtat gggcaatctt gcgatcctca tcgccaatga
    19141 caagaaatgt caacgaacag ccagcgatct cggtaatgtc gttgatccat ccatcgtgcg
    19201 actcaatcga attggcggac aggccgatca gcttgacgcc gcgcttggcg aattcggatt
    19261 ggtgcttggc taggtctgcc agttcggtgg tgcagacggg gtgtagtctt ccgcttttca
    19321 tataccttgc caccatcgag ttaggggatt tttgccacga tcctcttgat tacttgtggt
    19381 tcctttggtt ggatgcaagg gacttgaaca gcatatggcc cattctgact ctggggacaa
    19441 aggaaacagc actgtgctgc ttgcttgtgg atatctaggg gattttcagc aaaatattag
    19501 cagagttgtc tctgtaggag ggttaggatt agctaaccca aaataaatcc cacacttcca
    19561 ctcttctcaa aggccactgg ccgcagcatg aggcggaagg cagaggtgat ctttttccac
    19621 ccgccactgc accaatttag ccagcgtatg ctggctgatt ggtcttcttc tgtagtccgc
    19681 gacgtctcat gtctctcaac atccaatgtg atagaaaatg tagacatcgg tgcaaggagg
    19741 cctttccaac aaaatgcaac cctgtgcgat aacttgatat tagaaaaaag ttagggggta
    19801 cggaatggaa ataaagcaaa ccacaaagga tgactggtat gtcaacattc ttatgtgggt
    19861 aggcctgctg ctgcttgttt gactgctata ccccataact actatgttta gttgctttcg
    19921 gccaaagaga actgcggtga tatccttaag tggcatgttt taacgcctcg tatccacgga
    19981 aatgagcgcc tgtttgatat actttcctaa gaacaaaggc tgccaccatt atatcccctt
    20041 taggcgcctg acttggtgaa cctatattta attagtccta ctcgctggcc aatcatcagc
    20101 aggcaacgtc atcaaaagta gaatatcact atttagagat ggcgacgtgt tagtattcta
    20161 aacttgctta cgcgcgggca catctggtga acgttttaag ccactgtcta aagtagaaaa
    20221 cattaatgtg cagttatcaa aggccattaa ccacactaga acaactgtgc gattatctgc
    20281 ttagcttcaa tcctactcct aacagttcat atttacgctt aaatgatact cagactggca
    20341 tggacttcgc gtgatttatg taaacaacag cggtaactgt cttgatctgt atggttggtc
    20401 tgcataaccc agcggcaaac tgaaagagat tatttggcga aaagcttttg cctcctatta
    20461 taggaaccaa ccgacgcagt ctacttggct cgcgcctaca tccattcagg ttctgagatg
    20521 ctgatcatta tttactctca ttgcatccct ctgtacatcc accaaccccc tccatctcct
    20581 ttgtgctatt cagcgacctg taacattgac tttcttgtcg cttattttgt tatctgtaac
    20641 ttgggttaac tgagtcagta tgggtttggg cctgtatctt gcctatgatg gtgtgaacta
    20701 cgaatgtact atctgtgact ggcttttctg ttctaaatct gctctttatg cttattgcca
    20761 gcagacatca tgacaccaat ggtgtgaaag gtgtttctgg gtcttcattt taatataagc
    20821 aaaaaatata tatctttgaa cgtccagcag acataatgtt tgtttgacct gtccttaact
    20881 ataagacttt gctactagtg aagagcttta agaccactta gtaaatacct attatttttg
    20941 tctggagtgc aacgtctatt atggttctat taagcaacta caagaacatg aaattaacca
    21001 gcaccacctt tgcgtcaaat gcggtgacta ttttaagaat aagaataatt tataaatggt
    21061 aggtacacta gctagagttt agtagtttaa taagcctgtt gctaacagta tcttttcttt
    21121 agcattagca gagaaatcaa cctcgaaatc tagaatgcta tggttgttac taaaaattta
    21181 aatctgtttc cggaatgtta atctatctag agtctggaag ttgcgcgtca gatactacta
    21241 aggaggaaat taataatata gcccatgctt gttaccagcg ctggaagtat ataaataata
    21301 atcttaagga tagagggcag ctttacagct gccctagtta caaaataaag ttcttaaagc
    21361 tttctatact ttactaacat gcagaggatg tcctactgtg ctcttctcct ctcaatagat
    21421 atagttgtct ggctgagcta gcatgattta ttgcttgcag actacagtag cttcacgtct
    21481 tcctctgtgt catagttctg tataaaatgt gctggaatgt agttatccct ggccccttaa
    21541 aaccatttag cgcctttggg ttagtgaagc aagaattatg ctacagccat atctgaaaac
    21601 atgagggttt atatacaagg tgaatatcag attgattttt ttgtaatggg ccaaattgag
    21661 cgtcttccta tctgattagt tttaagatac tccagagtag tgctgcctga caggtttgga
    21721 aagattgaat tcctcctggg gaagatcaca tgtaaatatc acgtggactt ggccatgttg
    21781 taagagacag ccagatggtc aaatcaggac agcagtccac atgtgactgc tgtcaaagcg
    21841 agactgctgt taaattagga ctgctgttaa atcaggactg ctgtcttccc atgatagtga
    21901 tcattgttaa tggttttcaa ggctatataa atcagtaaat ataagttccc tggtctacaa
    21961 atgtcaacaa gatagcatct cagattaacc tagaatatta taggaaggta ctatatagtt
    22021 ttcctagtta gcaatatctc agcaacgaaa gctattaaaa acatagttac atcttgtagt
    22081 gagctcctct attacacttg atagattatg ttcaagtttg ataggcagtg gccaactctt
    22141 gccatgttat ccttaaaggt gcgggatagt gcaaagactt gcggccatta gtatagcccc
    22201 gaaattgagc aaaaggaaaa aaagcgggtt gttgggtttt ggggaggggg aaggggggag
    22261 gggggtttgt tgcgggcgga agtggggtgg gtagaaggga aaagaaagac gaaggcaaaa
    22321 gaaaaggaaa aagaaaagga aaaagaaaag gaaaaagaaa aggaaaaata aaaggaaaaa
    22381 taaaaggaaa aataaaagga aaaataaaag gaaaaataaa aggaaaaagg aagagaggga
    22441 ataaaaggga gaaggcctac caagtcttcc tgtgaaggga actatctgtt atctaagttg
    22501 aatatgtgaa tctgactgtt ctctttcaac tgaactatga gtgagatgtc tatattatat
    22561 tcctggcaga attcaaatac cttccggaac aacgtatctc ctcgtcgttt gtgttgttga
    22621 tgatttgcct taggcttatt ggactggcga tgacggattt ttctaggctt tgctatcctt
    22681 aggagttttc agtgatagta acagataata ggatagaatg agagcgatga cttcgggcgc
    22741 agaacctcga cggttcaggc ctttatatat tcctatgctc accttccccg cgcgaccgaa
    22801 gcgctttata gattcctatg ctcaccttgc ccgcgcgatc gaagtccaag aaagcagatg
    22861 caagatacat ctgaaacgcg ttaaaagtaa tctatagctc gtttaggtta agcgggcgat
    22921 tgactccaag caatctgggg tgagcgggtg atcagcgggt gatcaggggt gatcgggatg
    22981 agcttaactc tattgcaggg gtgtgataaa ggtggggctg aaggtccacc aacgccgata
    23041 agtcggctgg aaaggcgcgc tgaagatggc gtggcaccca tatcaatggg cgcaggccat
    23101 ctggaggcga gcatctatga gcctcttctc ccaatggaca agtatctccg cagggatgat
    23161 tgactccagc tggatgccta ggtccgcacg tgccagcatt ttggagctat cccttaataa
    23221 gacagcgttt cctgtttgga cgaatccccg catagtatga aatttacaat tagatcagac
    23281 ccctttgtta tgggacccat tgcttcccgt gactattgac ccactccatc ttggcttccc
    23341 catgtcagct gatagggaga ggtttaccgg ttatgttgtt aggttcgttc agtccttagc
    23401 aacctcatta atagcatagc aacccttgct tgcgttgaac taggcttctt gttcccgcgc
    23461 ttctacctcc tccaagaaga gagctctcta gtcgcatgat tgatgctgat gtcccggttg
    23521 cgaaagtcat gattctgttc gaagttctct cctgtcatct gttagcggct gaggcagcca
    23581 catgaaactc tttgacgggc atgtcgcaac catatcaacg actcagaaga tatcattgta
    23641 aggcaattct tttgtccatg ctgtagtgat gagagggtag gcaagtacag aaaacatcat
    23701 tgcattcagc atttggcgat tataggccga tgatatttcc gatgtcttct tccgatcaga
    23761 aaaaagttgt tgaagttcgc tttgagaggt cttcttgtgc tacggattta agtgaaatag
    23821 aaggaatgag caacgttcac ctcaccgcgg attggtgtca acctcagcat acttaataac
    23881 atgctcaagg agtaacagag gaatttcggg tttcttgatc ttccaggcag aaattactgc
    23941 cgcaaaactg gagagaatat gaagaggata gggaatttgc aaattcgctt acgtgatctt
    24001 ccttgtgatt tgtttaccca atgaattgtc tccatagtct caagctagta atccgtcctc
    24061 gacgagaagt acacactctt tccggatctc atcgcaatcc tccctgctca gactcgtcgc
    24121 acgcggcagt tgttttgcac catggagaag ctttgcttcc tctaagagat cacacaagga
    24181 agaaaaccca cccttccagc acctctcaat aatccgatcc agatcccctc cgttcaatgt
    24241 aggaaacacc atcttttgaa ggcgtttaac aatttctggg ccaccctcag tcagagtttc
    24301 gaactcataa ggctcatacc ccctttcatt gaatagataa tcgatccgat ggcaaactgc
    24361 tcggttctag cgccgcacat cccaaacgtg ccgttctcac ttcccgcttc agaacccagt
    24421 agacgcgccc atggaggtgc agcaccagca tatggctcgc cgacgctagc cacactatca
    24481 aaatccgcaa gtttaagatg atcctcggcg tctagaagca ggttcggcgg ccggatgtcg
    24541 ccatgcacgc gtccaagcga ctcgagccaa gagacggcac tgcagagctc catggtccat
    24601 cgctcaacca acggtgtggg ctcgattctg aagacttccg ttccattgcc cgtatgcctc
    24661 ctggtcaggc tagtctacaa aacaaaactg tatagttaat atgaaccaga aagagaatga
    24721 tatagcctag cccgtgttta agtagtagcg aaaggtttga aaaaaacatg ttgaattaca
    24781 gcggtatact gtacacagtg tacatacaat atagggtttg ctgtggagtt ccccaactag
    24841 ctgctaacat accacaatac tcatatctta agtaagacat gcatggctta tgcaacatac
    24901 agggatactc cagggttgtc actagtctca ctccccatta caggaggcct ataagctttg
    24961 gcgacgtgtg ggacaccctt ccagaagagt gatattgctt gtggggactt ttgtctacca
    25021 aaggctctat tatttcgtcg aaaactcctt gttacaatgt ccctccgtac gaagcccgga
    25081 tagtgctccc actattgagg tcagggctag gtcgtcagtg gccagctggg tggaaggact
    25141 cagattgcca tgtcgtgacg gtctcctttc aattaggtcc caatctggag tgacgccgtc
    25201 cctccccagc ccaccttggc cccctaccta taaaccatag tatgccttag aaccgaattc
    25261 ctatataagt caccgcacaa gacagttgca ccagagaacg gtccaatctt gcatcacaga
    25321 ggaatcaacg ccactatggt tattctctca actgaagacc accacaagca ggtcgatgac
    25381 ttcaatctat atagggagtt ctgggtttgg gtcaacaaca caaccacaac taatcttaat
    25441 gaaacataca ccattcaata gagcttaaag agaggaatcg aatgatggta ttatcattaa
    25501 aaaatatcca ggagtggtgg agatattcac aggcaaagat atgtaatttt aggacgctaa
    25561 ctgcttttga atttccgtta caatcctatt taagcatcat tgcattgtga tctgaggata
    25621 attaatacat ctaaaaatca agaaaaatct gctaatcaga acggtatgtc tctcatccta
    25681 tttagattag aggtgatgga gtaatccata gtaggctgtc ctagtcaagg aatggtttat
    25741 aaactaggaa gtgcactgcc tactgtaata gagtgattct taatctcagc atacattact
    25801 aggtcgagct ttaaaccagg tccccttaac aggaacctaa tctataaaac tattaagaat
    25861 ccactggaga gatgctggat cccttaaata actatattat atatatatag gcagtgttag
    25921 ggcgggtgta ttttaatagg ttatatttaa ctctactaca gtgggtaaag attacagcca
    25981 ccatagctgc aggcctgtat gttaggtaac taattatatt attctatttc cctagttact
    26041 ttgctataga atagctcctt tatatataac ttttactaca gaccagagag acatctaacc
    26101 ttgaagtctt tatatcccta actgacatgc catcttaaaa gttaaaaata gactaaatag
    26161 gcagaatgaa ctcaatgaag tgttgcagct agatgaactg gatgaactag ataaactaga
    26221 tgaactagat aaacaggaca aatgggacaa acaggacaaa tgggatgaac tagataaact
    26281 agataaacta gacaaatagg ataaactaga caaactgtca tggtgctgcc gtggatagga
    26341 gttagcgtcg ccaggaagga atcatatgac tctgggaata tcttcaccgc ataactcagc
    26401 aacctatttg aaggtccttg agctatgtcc tgtctataga gcctgcctgt accagtctac
    26461 cctgtaacta gaatagataa gatatagatt actgtagcta gtctgagtgt taacttcctt
    26521 attaactaac ttctatttac ctgtgatcca gcaccttgat attatatagc tcccccctta
    26581 gagttgacac tgtcagaatg cctgtccctc tgcccctgtt cctacctagc aaccctaaag
    26641 agttctctga gtatgttgct agccatagta ctgaatagta taaatactac tacctagcat
    26701 ataagtacat ctagaaggct gaattgacta ttaatgaagt aaactaataa gctaaacaat
    26761 ctaaggcctg actcctggaa ctctagtatg aactcactac cttagagcag agacataaat
    26821 aagagactac taaactaagg gctatcctat agtactagaa ggaatagctg taatagaagg
    26881 aatagtagta tatataggct gctatagaaa gggattaagc ctattgctta gctaccccta
    26941 ctataaatac acctatacct acatctgtgc ataaccctat tactaaaaag cctgtagtta
    27001 ctctagtagg aatgcctata ttaactacta ccctatcttc caaagctgct agattattag
    27061 aataactccc taaccctaat aagtttaaag gtgactaaaa ggaccttcag tatttcatag
    27121 catagattta agagaaaaca aatattaacc ttaaacactt cccaacaccg cagagctgga
    27181 tggcttatat aaataactgc ctgaaggatg cactatatac ctagattctc ccctatatta
    27241 agaagggaat ttgcaccctt aataactact aagatatcct agacatcctg gagcatgcct
    27301 ttggtgaccc taactgcgtg aataatgcct aaaataagct attcagcctg tgctagacta
    27361 ataaggagtt tagcaccttc tttatagaat ttcaacacct agccctggag ggtaagatac
    27421 ctaaggaaac cctgtctatc ctgcttgaac aggctattag ttacaaactc tggggcatgc
    27481 tcatgcacaa tcagcctcta agctgggagt actattagtt tgctagattc ctgcaggagc
    27541 ttgagaacca ctactagtaa tacactacta actagccccc tgttattaag acctatacta
    27601 ccactactaa acctaccctg cattcctagt caccctaaag ctctagccct attgctacta
    27661 agtctactaa gtaaccctag caccctatta tttaaaggaa cgagcatacg ccagcgtaat
    27721 aatataaccc tatagacctg ggtactaccc aatgtctaat aagaaagggg tatagcccct
    27781 cctgccgcga gacaggcgcc tgcttctgat atggctccct agaacactag attagggact
    27841 gcccccaccc taatacctat tagagagtat aaatcatggc gtcttataaa ccacgcccag
    27901 agagccccca gaggggatgg attccagaat ctagaagccc attgcccagc tagacctcct
    27961 tagtaaaagg agtaagcctg gagtaagcca taactaggct tagaaactat gtgttattta
    28021 aatttctgct gccgctgttt acagacttaa ccttaaggaa taaatataat aattaaaagc
    28081 tatgatatta cctgtgaccc tagagaggga agagaaggga ataaaactac ctacttacac
    28141 cctgttagat actagagctg aaggatgagg atttattaat aaaggatagg ctaaagatca
    28201 gaagctagag cctatccccc tagcagacct gataaccttg cacatatttg atgggagaga
    28261 actagagaat gggaagataa cccattacat ttagatggat ataagaatta aggactactt
    28321 tgagaaagat gtgaggtttt atattatcta gttagcatac taccctatta tgctaggaat
    28381 accttggata aaggtatata accccctaat atgatttaca gcccacagca ttatgtttaa
    28441 tagcaactac tactagaaat actataatac tctccagagg ctaactaaga tacaagccct
    28501 gtataacatc cccccaaaga cctaacctag acacctgccc ctgagactaa agggactaga
    28561 gaatagagat atagctttta tcttcttagc tgcctgctta gcttacgcct ggagaaatgc
    28621 ctagatgttt ataattaccc tagaagatct taaagccgcc ctgaggattg ggaaagctca
    28681 gaaggaagat cttactaacc tattacctaa taaattcaaa gactatgcta atattttctc
    28741 ccctaaggag gctgagtgcc tgccaccata ctgcccctac aaccataata ttaagctgtt
    28801 agagggaaag acccccctgt ttagccctct gtacactatg tcctgagaag aattaaaagt
    28861 cctgaaagaa tggattgaag agaacctaag gaagggcttc atctgcccta gttcatcacc
    28921 cgctatgttg cctatcctat ttattaaaaa gctaggtgga ggcatacaaa tctgcgttga
    28981 ttactgagcc ctaaatatta tagctattaa agactgatac ctactgcccc taataaagga
    29041 aaccctaaat aacctaaaag ggatgaaata tttcataaag attgatatta ttttagtatt
    29101 taataatata tgcattaaga aaggacaaga atacctgaca gctttccata cctaactagg
    29161 cctatttaag tccctagtaa tgccctttag gctgacagga gcacctgcaa ccttttagca
    29221 atttattaat aataccttat gagattacct taatgtcttc tgcactgcct accttaataa
    29281 tatccttatt tacagcaaga cctatactaa atatataata tatatccact ctgtcctgca
    29341 gaaactaagg gaagccagcc tgtatataaa aatctaaaag tataagttta ttatccctga
    29401 aaccaagttc ctaggtatta tcattagcca ggatagcatt tatatggatc ctaataaggt
    29461 gaaaataatt atcaactggc aagttctaac ctgtgttgct aatattcagg cctttattag
    29521 ctttagcaac ttttactagt gatttattaa ggatttctct aaaattatta ctcccttggt
    29581 gaacctgact aggaaggatg tcctatttat gtggactata gcctgtaaat taggctttaa
    29641 agccctgaag aaggtgtttg tgaatgccct aatcttaaaa ctatttaact agataaaaga
    29701 tgttatggtt aagactaact cttctgatta tatatctact agtgtgatgt cttagtataa
    29761 tgataaagga gtcctgcacc ctgttatatt cttctctaag aagctctcag tcactaagtg
    29821 caactatgag atctataata aagagttgct tgctattatt cactatttta aggaatggca
    29881 ccctgaacta gagggtacac tatcactaat taaagttata actaattatt gtaacctaga
    29941 atatttcata tctattaagc tacttaatag atgataagct tgctagtctg aattcctgtc
    30001 ctactttaac tttaaaatta tatatcaacc taggaagcag ggagttaaac ctgatgctct
    30061 gactagaagg ttagaagatc tccctaaaga gggggatgaa tggctacaac accagagcta
    30121 gataattcta aagaaagaga accttgaccc tgagatttag aacttagtaa aactagaagc
    30181 cattataagg agccagtcag ccataagaag agttcacttt gcagacccag tggcccaagt
    30241 tgctagaaca cctaaggaac ctaccagagt gcctgcttaa ccagcataga cagaccagcc
    30301 agaccaacca gactagctag accaaccaga ccaaccagac caaccagacc aactagacca
    30361 accagaccaa ctagacaaat cagaccaact ggaccaactg gattaactag actaactaga
    30421 ccaactagac caaccagact aaccagacca accagaccaa ccagaccaac tagaccaacc
    30481 agaccaacca gagccccctc ccagtatcaa agaactacta gacactgcct actagttaga
    30541 taatactgta cagtccatcc tacaagcact ggataggaat gctagttaat acctaaagat
    30601 caccctagct gattgcagat gataaggaag ctatctatac tactgcgaat acttatacat
    30661 ccctaactat gataagctga gagcctagtt attacaggaa tgccatgata agcctactgc
    30721 tagacaccct ggaaagtata agttatataa gttgatagca cgggaatatt actggccggg
    30781 catgtactaa tatattaact gctagaccta aaactgccac acctgctgct gatccacccc
    30841 atcttataaa gcctatcaag gagtgttgta cctgctccta gtacctaaat aatcatagca
    30901 agatatctta atagacttta tcactagtct agtacctagt caaggctaca atgccatact
    30961 agttattatt gattgactta taaagataag gcactttatc ccttgttgga ctacctgtga
    31021 tgctaagggt gtagcctgat tatatatcca tcatatatag aagctacatg gcttactaag
    31081 gataatagta tcagactgtg gcccttagtt tattactgtg ttctggaagc acctgactta
    31141 acgcctagat gttaagaacc tactgtctac tactcattac cctaagacta atggctaaac
    31201 taaaagaata aatgctattc tagaacaata cctgcacacc tatattacct atctataaga
    31261 tgattgggcc gactggttac tattagctga gtttacctta aactctgtct aatctaaggc
    31321 tactagaatc tcacccttct tcataaatta tggatttcac ccatgcatgg ggtttgaacc
    31381 tatctagcct gtgaattacc ctgctactag agatactaag gcctttgtaa agaaaataca
    31441 agatgttatt aactatatcc gtgcccagat ctatattacc caggcctatt atgaggaaca
    31501 gacaaatcgc cactggagac ctgcctacta ttactatgta agataactag tttggttaga
    31561 tgcctggaat attaagaccc tgcgccccta gaagaagctt gactagaaat acctagggct
    31621 gttctgtatt aagaaggtta ttagcctgca cgcctatgag ctagatctgc cagcttctat
    31681 gaagattcac cctgtgttta atattagctt actatgccct gttgctaaag accctgttcc
    31741 tagacaaaga taaccactgc caccactagt agaagttaat ggcctagaag aatggattat
    31801 tgaggacatc ttggattcct gctgggaaca ctggggctga tggggcccct gtctgaagta
    31861 tactgttaaa tagttaggct atgataaccc cactgaggaa cctgcctatt acctatggaa
    31921 cgcataagag attattgcta acttccacca ctgctaccta agcaaaccta aaccagcaga
    31981 tggtcttggc ggagcttaac cctgaggagg ggagtactgt catagtgctg ctgtggatag
    32041 gagttagcat caccagaaag gaatcatgtg actctgggaa tatctttact atacaactta
    32101 gcaacctatt taaaggtcct taagctacat cctgtctata gagcctgcct ataccagtct
    32161 gccctgcaac tggaacagat aagatataga ttgctgtagc cagtctgagt gtcaacttcc
    32221 ttattaactg acttctgttt acctgtgatc cagcaccttg acaactacta gagttaaaag
    32281 ggtataatta cctaataata gtcactaaca gactcatgaa atttatctat ttaattctaa
    32341 taataatgaa gatgacagca tcataactta taagcctact tatagggcat atgattataa
    32401 atcatagaat gctatgatac atcacgttag acagagataa attatttatg tcaaagtttt
    32461 agtaattatt aataaactta ataggaatta agtaaagact tatgactata tatcatctgc
    32521 aagccaatag acaaactaaa taaataaact aaataattaa ataatattta taacactaca
    32581 taaattacca gcaagatgat taggtagttt acttactaat agcatagttc acatataata
    32641 atactattta tttaactaca ggggaaacac ctttctttgc taattacaga tataacccta
    32701 tattaattag agaaccgcaa aacaaagtac ccacagtgga agaagccgcg gaaatggtgg
    32761 atactattga ttatttaagg actcaacttt taaaagacat tgaattcatg aatctctgta
    32821 tagtaattta ctatgattag aagcacagga gtactctatc ccacaagcca tggaccatcg
    32881 ctattccgat gggcctaggg tgtagctagg gttaaatgct gattggttgg tttggacgat
    32941 ggtcggggtc cgatggga
//
