LOCUS       CM000172               23327 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 4, whole genome shotgun
            sequence.
ACCESSION   CM000172
VERSION     CM000172.1
KEYWORDS    .
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2023-11-23 15:43:59
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: <3149630
            Orig. end    :: 3172957
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(join(1..960,1030..1359))
                     /EC_number="2.4.2.18"
                     /codon_start=1
                     /locus_tag="AFUA_4G11980"
                     /note="encoded by transcript AFUA_4G11980A; GO_component:
                     GO:0005634 - nucleus; GO_component: GO:0005737 - cytoplasm;
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity; GO_process: GO:0000162
                     - tryptophan biosynthetic process"
                     /old_locus_tag="Afu4g11980"
                     /product="anthranilate phosphoribosyltransferase, putative"
                     /protein_id="EAL89595.1"
                     /transl_table=1
                     /translation="MLSAHEFDQKPNQVSISPLLQKLAYPTTQVPVDPAEIASAFALIF
                     EDRLSAIQTAALLTLLHSTGKDRDAQVIALCSLRMREAASQIEKSSLQKAIKARGKKEG
                     NYGGGLCDIVGTGGDSHSTFNISTTASIIASPLLMMAKHGNRAQTSFSGSADVLNAISP
                     VPPKISAVTAENLAQVYEATSYAFLFAPNFHPGMMYANPVRRGLGLRTIFNLMGPLANP
                     VDWALEARVVGVAYQSLGPVFAEALRSSGVTKALVVCGAEDLDEISCAGPTNCWKLTGY
                     PNPDYDGPDEDCSCDEDENIPRTLVKIETFQLHPSDFGLPAHPLSAVYGRKMPKENAAK
                     IMSILRNELPPDDPILTFVLINVAALLVISGICEADTSNMGPGDDGKVITERGPGGGRW
                     KEGVRRARWAVESGSALKCLEQFIEVTNRL"
     region          <1..23327
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="4"
                     /tool="antismash"
     subregion       <1..>13327
                     /aStool="cassis"
                     /abundance=6
                     /abundance_left=3
                     /abundance_right=3
                     /contig_edge="False"
                     /gene_left="AFUA_4G11980"
                     /gene_right="AFUA_4G12040"
                     /genes=7
                     /label="AFUA_4G12040"
                     /motif_left="+07_-10"
                     /motif_right="+00_-06"
                     /motif_score="7.4e+04"
                     /motif_score_left="6.9e+04"
                     /motif_score_right="4.7e+03"
                     /note="best prediction (most abundant) for anchor gene
                     AFUA_4G12040"
                     /promoter_left="AFUA_4G11980+AFUA_4G11990"
                     /promoter_right="AFUA_4G12040"
                     /promoters=5
                     /subregion_number="1"
     gene            complement(<1..>1359)
                     /locus_tag="AFUA_4G11980"
                     /old_locus_tag="Afu4g11980"
     mRNA            complement(join(<1..960,1030..>1359))
                     /locus_tag="AFUA_4G11980"
                     /note="transcript AFUA_4G11980A"
                     /old_locus_tag="Afu4g11980"
                     /product="anthranilate phosphoribosyltransferase, putative"
     PFAM_domain     complement(join(43..960,1030..1032))
                     /aSDomain="Glycos_transf_3"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00591.24"
                     /db_xref="GO:0016757"
                     /description="Glycosyl transferase family, a/b domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G11980_0066"
                     /evalue="6.80E-54"
                     /gene_ontologies="GO:0016757: glycosyltransferase activity"
                     /label="AFUA_4G11980"
                     /locus_tag="AFUA_4G11980"
                     /protein_end="416"
                     /protein_start="109"
                     /score="183.3"
                     /tool="antismash"
                     /translation="LCDIVGTGGDSHSTFNISTTASIIASPLLMMAKHGNRAQTSFSGS
                     ADVLNAISPVPPKISAVTAENLAQVYEATSYAFLFAPNFHPGMMYANPVRRGLGLRTIF
                     NLMGPLANPVDWALEARVVGVAYQSLGPVFAEALRSSGVTKALVVCGAEDLDEISCAGP
                     TNCWKLTGYPNPDYDGPDEDCSCDEDENIPRTLVKIETFQLHPSDFGLPAHPLSAVYGR
                     KMPKENAAKIMSILRNELPPDDPILTFVLINVAALLVISGICEADTSNMGPGDDGKVIT
                     ERGPGGGRWKEGVRRARWAVESGSAL"
     protocluster    1026..23327
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[11025:13327]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11026..13327
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1026..23327
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     PFAM_domain     complement(1108..1269)
                     /aSDomain="Glycos_trans_3N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02885.20"
                     /description="Glycosyl transferase family, helical bundle
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G11980_0065"
                     /evalue="3.60E-06"
                     /label="AFUA_4G11980"
                     /locus_tag="AFUA_4G11980"
                     /protein_end="84"
                     /protein_start="30"
                     /score="26.9"
                     /tool="antismash"
                     /translation="PVDPAEIASAFALIFEDRLSAIQTAALLTLLHSTGKDRDAQVIAL
                     CSLRMREAA"
     promoter        1309..1559
                     /locus_tag="AFUA_4G11980"
                     /locus_tag="AFUA_4G11990"
                     /note="bidirectional promoter"
                     /seq="GAGATCGAAACCTGATTAGGCTTCTGGTCAAATTCATGCGCAGACAACATGGT
                     GACCTGAGTAGAGCGCTACTCTTCAAGACACTTGAAAATGACTCCAAATGTCAGCAATG
                     ACAAAGGAAGGTGGAAGTAGCAAACAGCCCCTCAGCTTGTATCACCGGAGGAGTCATCG
                     GCACTCGGCAGAATCTCACCGCCCACCTAATGGACTATACCGGATCGAGGACATCGTCC
                     ATTGTTTCTCCCAGATTTTGG"
                     /tool="antismash"
     gene            <1510..>2763
                     /locus_tag="AFUA_4G11990"
                     /old_locus_tag="Afu4g11990"
     mRNA            <1510..>2763
                     /locus_tag="AFUA_4G11990"
                     /note="transcript AFUA_4G11990A"
                     /old_locus_tag="Afu4g11990"
                     /product="conserved hypothetical protein"
     CDS             1510..2763
                     /codon_start=1
                     /locus_tag="AFUA_4G11990"
                     /note="encoded by transcript AFUA_4G11990A"
                     /old_locus_tag="Afu4g11990"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL89594.1"
                     /transl_table=1
                     /translation="MDYTGSRTSSIVSPRFWFLCVPSIIHRPRLSAPTIARDYHALCFL
                     RACTDIITLADRQILHFRFTMPPRLRLANGRISFRRQRVLCQFELPVAARYASTATRAT
                     TPAASIEQMTSSIPPLARYPPSQPPSHRNPEYRRSQLLRQYTSLIRTTPLMVLFQHDNL
                     RSVEWTAIRRELSKAMQKVDEKIAADGRQAQPLAPHIKVQIVQTSIFEVALRIVEYFRP
                     DRTTVANAKPPRAVDPVTQTSAEIPPSGSKDDPTLTHDLSRAAHDAVMYMKGKHELSAL
                     LVGPVAVLSIPQVSPEHLKAAMSVLAPKETGFPAPTRRANPAWHEPPVQNGLQKLSLLA
                     ARVDGQVFDVDQTKWVGSIEGGMDGLRSQLIMALQSMGSSITNALAGAGKSLYFTLESR
                     RSVLEDEQKGPEGDKNES"
     gene            complement(<3098..>4531)
                     /locus_tag="AFUA_4G12000"
                     /old_locus_tag="Afu4g12000"
     mRNA            complement(<3098..>4531)
                     /locus_tag="AFUA_4G12000"
                     /note="transcript AFUA_4G12000A"
                     /old_locus_tag="Afu4g12000"
                     /product="phosphatidylinositol phospholipase C"
     CDS             complement(3098..4531)
                     /EC_number="4.6.1.13"
                     /codon_start=1
                     /locus_tag="AFUA_4G12000"
                     /note="encoded by transcript AFUA_4G12000A"
                     /old_locus_tag="Afu4g12000"
                     /product="phosphatidylinositol phospholipase C"
                     /protein_id="EAL89593.1"
                     /transl_table=1
                     /translation="MVAEHLTIRNLTTTPIILKLIERFHPHKDPRDDIHSLARNFTRIL
                     SNVTRTNETVAAITDDNEPFAHEEYDIHVEPFQTVQTEVRAFIDSDKERLRWTFEAEGE
                     RHQIQTPVPTTESAGMKALCDNPRFRFTGVYVTPESHLAIYSSANLQAWMGELKDSTLL
                     SSLSIPGTHNSPTCHVAAPSVRCQAVSPREQLRNGVRFFDIRVQPQFPEDPSKDELILV
                     HSVFPISLTGNKYFRDLMRDVNEFLNENPSETLIISLKREGPGNHTDEQLSRIVRDHYA
                     RPDSRWYTEPKIPTLGEVRGKVVLLRRFNIIEELKHEHDGRGWGIDGSDWADNTPNATC
                     SSGQLCIQDFYEVLETKNIDVKIKYVTEHCERSSGHCYPFGALPDPEASKAHPFYINFL
                     SASNFWKVGTWPEKIAAKLNPATVDYLCRRHSHPDGDWSTGILVTDWVGHEGDWDLVRC
                     IVGMNAKLKMRQMREEQEH"
     PFAM_domain     complement(3608..4033)
                     /aSDomain="PI-PLC-X"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00388.22"
                     /description="Phosphatidylinositol-specific phospholipase
                     C, X domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12000_0067"
                     /evalue="1.40E-10"
                     /label="AFUA_4G12000"
                     /locus_tag="AFUA_4G12000"
                     /protein_end="308"
                     /protein_start="166"
                     /score="41.0"
                     /tool="antismash"
                     /translation="SIPGTHNSPTCHVAAPSVRCQAVSPREQLRNGVRFFDIRVQPQFP
                     EDPSKDELILVHSVFPISLTGNKYFRDLMRDVNEFLNENPSETLIISLKREGPGNHTDE
                     QLSRIVRDHYARPDSRWYTEPKIPTLGEVRGKVVLLRR"
     promoter        4481..5658
                     /locus_tag="AFUA_4G12000"
                     /locus_tag="AFUA_4G12010"
                     /note="bidirectional promoter"
                     /seq="ATTATTGGGGTTGTGGTAAGGTTGCGAATCGTCAAGTGTTCGGCCACCATTGT
                     GCGACAAGCCAGTGCTCAATTGAACAGTCTATCACGTACAGCAGAAGCCAGTCCCGAAA
                     TGCAAAATATGAACCAGATGGATAGGAGAACGAGTAGGGAGTGAGAAGAGAATACTGCC
                     GCCTGCTCTTCTCGGCCCTCAGAGGGTGCTTAGCCCTGACAAGACTAGAAGATTAGGTT
                     GCACCAATGATGGTTCGATCCTCCGCAATGGGATCTCGCAGTCCCACGTTCATCGTGCC
                     AGTAGCTGGAACCCTAAGCATCATCTTAAGACAACACACAAGACACACCAAATTGTACT
                     TGGAGAACGGGTACTTTTACCCGTTCTGAGCTGGAGACTGAGCATTATTGAACAGATAG
                     CAACTTGGCTGGCACTAAAGTCAGACTCAGAGACTCAATCACAGCACAAGGCAATAGAT
                     GAAATAGTGGTGGTGGGTTGTCATTGCTCAGCTCCACCGTGATGAGATAATCGTGGGGT
                     TTCACAAAATAATGACTAACAGAGGGGAAGGTAGGCGAGTCGTGGAGATAAAAATCTCG
                     ACCATGCACATCATTGTCGCGATTTTCGAATACTCCATAGCTCTGCTTGGTAATGAAAA
                     AAAGTATTTGCATGGATTGCAGCAAATTTTCTTGCTGAACAAGTAGATATCCCTGCTCT
                     AATCAAACGAGCACTCAGTGAATATTGGGTACCGCCGGCTTGAGTTGAAGCAGGGTTTG
                     ACTCAGCTTGAGTGACTCGCAAAATCGAATCGGATTCGATTCAGCTACGATCTTTTGCT
                     CAACAAGGAGGAAACAATGGAATCGAGCTGTTCAACAAGGCACCATTCCTGAAGCTTTC
                     AGTATTTGAGTTCGGATGAGAAGACGGACCGAGCCACAAGAATACTTTCTCGATTGATA
                     ATGCGGAGTAAATCACGTGGGGTGACGCTGTGCTCGGTTACTATCGGCGATGGGGAGCA
                     ATAATGCGGAGAGACCCTGTGTAGTCCTCCTCCTACTAATAGGGACAATTCCATGATGT
                     CTCACAGTTTTTCTTCTTTGGAAAACTACCCTATCTCTATATTCCCATTCTCGATTGCT
                     TCATAATTGACTATGAGCTTTTTGCGCTGCAACAGAGGTGTTCTGGGGGCCCTCAGGTC
                     CTCT"
                     /tool="antismash"
     gene            <5609..>7212
                     /locus_tag="AFUA_4G12010"
                     /old_locus_tag="Afu4g12010"
     mRNA            join(<5609..5780,5845..5914,6072..>7212)
                     /locus_tag="AFUA_4G12010"
                     /note="transcript AFUA_4G12010A"
                     /old_locus_tag="Afu4g12010"
                     /product="2-oxo acid dehydrogenases acyltransferase,
                     putative"
     CDS             join(5609..5780,5845..5914,6072..7212)
                     /EC_number="2.3.1.-"
                     /codon_start=1
                     /locus_tag="AFUA_4G12010"
                     /note="encoded by transcript AFUA_4G12010A; GO_component:
                     GO:0005759 - mitochondrial matrix; GO_function: GO:0005554
                     - molecular function unknown; GO_process: GO:0006099 -
                     tricarboxylic acid cycle; GO_process: GO:0006103 -
                     2-oxoglutarate metabolic process"
                     /old_locus_tag="Afu4g12010"
                     /product="2-oxo acid dehydrogenases acyltransferase,
                     putative"
                     /protein_id="EAL89592.1"
                     /transl_table=1
                     /translation="MSFLRCNRGVLGALRSSRPQRVIPTIPSSKISIPRRSFHPALPFW
                     AIKSQILKDVGEGITEVQIIQWYVEEGAHIEEWKPLNGMHVHVQLKGEDNPRLTLCSSQ
                     ALCDIEVEDGKYPDDHTPTEPKPEQLQPDPVAADTLSVQSTASTPLPPSQANETTVEAP
                     RSKYASLATPAVRGLLKTYNVDILDVKGTGKDGRVLKEDVNRFIAMRDASAQARSVAPA
                     SQQTETTVNLTPIQSQMFKTMTRSLTIPHFLYADELKINDITALRKKLASDPKDPKKVT
                     FLPFVIKAVSLALNEYPLLNAKVDLSIPEKPKLIMRPKHNIGVALDTPQGLIVPNIKDV
                     ANRTIMEIAAEIKRLSALGKEGKLTPADLSGGTITVSNIGNIGGTYVGPVIVPTEVAIL
                     GVGKSRTVPVFDDAGQVTKGELVNFSWSADHRVVDGATMARMANKVREFIESPELMLLN
                     LK"
     PFAM_domain     6337..6438
                     /aSDomain="E3_binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02817.20"
                     /db_xref="GO:0016746"
                     /description="e3 binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12010_0068"
                     /evalue="4.30E-12"
                     /gene_ontologies="GO:0016746: acyltransferase activity"
                     /label="AFUA_4G12010"
                     /locus_tag="AFUA_4G12010"
                     /protein_end="203"
                     /protein_start="169"
                     /score="46.3"
                     /tool="antismash"
                     /translation="LATPAVRGLLKTYNVDILDVKGTGKDGRVLKEDV"
     PFAM_domain     6502..7200
                     /aSDomain="2-oxoacid_dh"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00198.26"
                     /db_xref="GO:0016746"
                     /description="2-oxoacid dehydrogenases acyltransferase
                     (catalytic domain)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12010_0069"
                     /evalue="1.70E-79"
                     /gene_ontologies="GO:0016746: acyltransferase activity"
                     /label="AFUA_4G12010"
                     /locus_tag="AFUA_4G12010"
                     /protein_end="457"
                     /protein_start="224"
                     /score="266.7"
                     /tool="antismash"
                     /translation="QTETTVNLTPIQSQMFKTMTRSLTIPHFLYADELKINDITALRKK
                     LASDPKDPKKVTFLPFVIKAVSLALNEYPLLNAKVDLSIPEKPKLIMRPKHNIGVALDT
                     PQGLIVPNIKDVANRTIMEIAAEIKRLSALGKEGKLTPADLSGGTITVSNIGNIGGTYV
                     GPVIVPTEVAILGVGKSRTVPVFDDAGQVTKGELVNFSWSADHRVVDGATMARMANKVR
                     EFIESPELMLL"
     promoter        7213..7931
                     /locus_tag="AFUA_4G12020"
                     /seq="GCAAGAGTGGTTCTTCCGTCACAGTGATAGCAGGTTCTAATATAGCAGTTATA
                     GAGTTAACCTGACAAAGCGATTGAAAGTCAACAGGTAATCTGCTTCTGAGTCTGTTGTG
                     ATGGAGTCATGAACACCAAGTCCTACTATTGTGTTTTGATGAATAGATGTTTATCCCAA
                     GACCGTTGGCAGTGAATTCTCATTTTCTTTTAAATTCTGTGTTCATATCTTCTTTCATC
                     TGTTTGCTCAAGGCTGTGCGTACTGGTATCAACAACCCCTCCTCATAGCTCTCAGCCTC
                     TCACCACTCCCCACTCACAACCTCCAACCTCAATTTTCTCCTTTGCACTCTCATTCTTT
                     TGATTCATACTTTGCTTGCCCTATTGCTGTTACTTTATGAGAAGTGTAACCCTCAGTCT
                     ATCTTGTAGCCTTTGTTTCTGTCCTGAATAGTGACAGCAAACAGTCAAGATGGGTACAA
                     AAGGACTTCTCTTCATCCGCTGCCGCGGCAGATACTTCGTCATCTGGAATCAGCTTGAC
                     AGCTATCCTGAGGGACTCGGAGATGCTATTGTTCATGAAATACCAACTGATCCTGAGGG
                     CTACCGCAGTAGGAGAAACACCATGATTCTGGATGCTGTGCACACTCACTGACACATTT
                     GTTTTCGCTAGATTGGCTGAATTCGATGAGGGAGATGTATTCCCGTTCTGCACAGAAGT
                     TCGAAGATCAGATCCTC"
                     /tool="antismash"
     gene            <7882..>10218
                     /locus_tag="AFUA_4G12020"
                     /old_locus_tag="Afu4g12020"
     mRNA            join(<7882..9566,9627..>10218)
                     /locus_tag="AFUA_4G12020"
                     /note="transcript AFUA_4G12020A"
                     /old_locus_tag="Afu4g12020"
                     /product="conserved hypothetical protein"
     CDS             join(7882..9566,9627..10218)
                     /codon_start=1
                     /locus_tag="AFUA_4G12020"
                     /note="encoded by transcript AFUA_4G12020A"
                     /old_locus_tag="Afu4g12020"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL89591.1"
                     /transl_table=1
                     /translation="MREMYSRSAQKFEDQILTVDVKIEQDDLTISERHAMSYLAIDDRL
                     IYAPIQTIMDRFSNDLIIEWTYTIDLDREMFAVDDAACFKLFNIPRGGRWIRYLAEDAQ
                     RRRKLSDNTPKDIIADISWKPNINPNLRVLGEALNIEPLSLTDFAAETMLRLDLDTTVD
                     KQMMPVRINFLMTTFLQMCRVYRKILDRFVLAWEPSCFMFREMAFAVLSLAAGEVFFEF
                     SEVLDAKYRENGYYLLPDSRTPKYHTRMLPRFIHESHLPGIEPGSAPKSTSFWFHDVLV
                     HLNSRLDLDDVEEASVVAVVNDGLDQGYEEFYAMVLSILDVVLIRVQKGRDGKPYIRRS
                     PLMALFEFTEENSGYAHGPRTRLSQSQQGLNKQDSHGAKQKDTSPGESDAAEEDGAASD
                     ISADPAAAGYFTFMLMYHFFNAAAAERLAGTRSLLFPNEILSLIMDFSDMRTYLALAQS
                     SAFCHELSHHKLRLNDEYAVIGSGEDSETFVLEDLHSGKKIHSKLSMYQKNWLGHPIAD
                     GLKLSPVIGVTNTKRLSIMDDVTIQLSDVTPKDPVWSEAEEGSSQEQHGWSFPPNEEDG
                     DLIFNLPNDAYLGAVETAWGRYLSKLARDAGEPDSEFFSTMLRNRLYRCLLPPGYRELG
                     MEPFLCSGFHAFFRHERDKTPEEWEQTLQYVARQLSKLEVRPRERFRRWGHPVIVAFSA
                     RVKLFYYVFHREVKPPICSNPKSYTVEIADKCTDPNSGRRLVQLIAGEDPIDLKDDDGR
                     MRFES"
     gene            complement(<10243..>10655)
                     /locus_tag="AFUA_4G12030"
                     /old_locus_tag="Afu4g12030"
     mRNA            complement(join(<10243..10440,10638..>10655))
                     /locus_tag="AFUA_4G12030"
                     /note="transcript AFUA_4G12030A"
                     /old_locus_tag="Afu4g12030"
                     /product="hypothetical protein"
     CDS             complement(join(10243..10440,10638..10655))
                     /codon_start=1
                     /locus_tag="AFUA_4G12030"
                     /note="encoded by transcript AFUA_4G12030A"
                     /old_locus_tag="Afu4g12030"
                     /product="hypothetical protein"
                     /protein_id="EAL89590.1"
                     /transl_table=1
                     /translation="MLVLAVNRPQAAEQIGEHQDPKDAAWLTQSDSHLSSIFMPFIVFS
                     SVLSIVVFIIHLSLLLKLFGVWIVLQ"
     promoter        10605..11024
                     /locus_tag="AFUA_4G12030"
                     /seq="AAGATAAAAGGAAGAAAAATTGAAAAACGTACAACAGCCAGGACGAGCATTAG
                     CGCTGGAGGAACTTTAGAAGGTCGTTGACCCCTTTAAGCAATCTCTTCTGCCTCGCTCA
                     GTAGCAGCACAAAGAACTTGAGACCATGATGCAGACTACATTACCTTCAGATAAGGCCT
                     CTGTAGGCCCGTTGGCAAGCTATAATAATAGGGTTAGGGGCGATTGGGGCCCTGCCTCT
                     AGGTGCACGCAGCAGATGACAAAAGTATATGACATGCTTCCTTATTATCCGGCCCGTCT
                     GTGATATATACGAGGTCTGCTCCAAGAGAAGGGAAAACTCAAGCTTCAGTTTCTGAATT
                     TACGGAGTCCTTGGTTGAAGAAGGGAACCCGAGAATTACTGCTTTATTGATACATCCAT
                     TGTGGCCCACCTC"
                     /tool="antismash"
     gene            complement(<11026..>13327)
                     /locus_tag="AFUA_4G12040"
                     /old_locus_tag="Afu4g12040"
     mRNA            complement(join(<11026..11310,11385..13100,13181..>13327))
                     /locus_tag="AFUA_4G12040"
                     /note="transcript AFUA_4G12040A"
                     /old_locus_tag="Afu4g12040"
                     /product="lanosterol synthase, putative"
     CDS             complement(join(11026..11310,11385..13100,13181..13327))
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_4G12040"
                     /note="encoded by transcript AFUA_4G12040A; GO_component:
                     GO:0005783 - endoplasmic reticulum; GO_component:
                     GO:0005811 - lipid particle; GO_component: GO:0005886 -
                     plasma membrane; GO_function: GO:0000250 - lanosterol
                     synthase activity; GO_process: GO:0006696 - ergosterol
                     biosynthetic process"
                     /old_locus_tag="Afu4g12040"
                     /product="lanosterol synthase, putative"
                     /protein_id="EAL89589.1"
                     /sec_met_domain="terpene_cyclase (E-value: 8.6e-18,
                     bitscore: 60.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNRLAKTDYSRWRMLDEDGKHTWHYLDDDEAARTWPQTLADKYYL
                     GLPLDLPDLPTATSPLDSAINGLKFFSKLQLPPGNWGCEYGGPMFLLPGVVIAWVVTET
                     PIPQAYAIEIKNYLMARANPVDGGWGLHSEGDSSVFGTSLNYTVLRLLGVDSEHPVMVQ
                     ARGLLHRLGGALNAPHWSKFWLAVLGVCDWEVVNPVPPEAWLLPDWVPVAPWRWWVHIR
                     QVFLPMSWIWSKRWTAAETDVVRALRRELFVQPWESIEWAAHRNDIAPTDNYHPKSWLL
                     NSVNWILSNIWIPYLRPRSLATRAEDWVSKLIDMEDANSDYADLASVNGPLNMIVCYIR
                     DGPDSYSVRRHRERMEEFLWVNKEGMLANGTNGVQCWDTAFLIQAVWSAGLAEDAQFKP
                     MLVQALEFLDRQQIRENCQDQGVCYRHVRKGAWAFSNRDQGYGVSDCISEALKAVIVLQ
                     KEADGYPQLLEDQRIFDAVDTLLTYQNPSGGCASYEPTRGSEYLEMLNTAEVFGRIMVE
                     YDYPECTSAVLTALVLFSKHWPDYRREEIQTFIQRGVDFIKRAQRPDGSWYGSWAVCFT
                     YGTMFALECLRSAGETYENSEHVRRGCEFLLSKQREDGGWSESFQSCEQMTYIEHPTGS
                     QVVQTAFAIIAVLSVDYPDVEPIHRGVRMIMSRQQRNGEWLQEGIEGIFNKSCAITYPN
                     YKFIFPILALGKFGRKYPHLV"
     PFAM_domain     complement(join(11053..11310,11385..12122))
                     /aSDomain="SQHop_cyclase_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13243.9"
                     /description="Squalene-hopene cyclase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12040_0071"
                     /evalue="1.20E-47"
                     /label="AFUA_4G12040"
                     /locus_tag="AFUA_4G12040"
                     /protein_end="707"
                     /protein_start="375"
                     /score="162.6"
                     /tool="antismash"
                     /translation="CWDTAFLIQAVWSAGLAEDAQFKPMLVQALEFLDRQQIRENCQDQ
                     GVCYRHVRKGAWAFSNRDQGYGVSDCISEALKAVIVLQKEADGYPQLLEDQRIFDAVDT
                     LLTYQNPSGGCASYEPTRGSEYLEMLNTAEVFGRIMVEYDYPECTSAVLTALVLFSKHW
                     PDYRREEIQTFIQRGVDFIKRAQRPDGSWYGSWAVCFTYGTMFALECLRSAGETYENSE
                     HVRRGCEFLLSKQREDGGWSESFQSCEQMTYIEHPTGSQVVQTAFAIIAVLSVDYPDVE
                     PIHRGVRMIMSRQQRNGEWLQEGIEGIFNKSCAITYPNYKFIFPILALGKF"
     aSDomain        complement(join(11053..11310,11385..13052))
                     /aSDomain="TIGR01787"
                     /aSTool="tigrfam"
                     /description="squalene_cyclas: squalene/oxidosqualene
                     cyclases"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_4G12040_0009"
                     /evalue="6.00E-201"
                     /identifier="TIGR01787"
                     /label="AFUA_4G12040"
                     /locus_tag="AFUA_4G12040"
                     /protein_end="707"
                     /protein_start="65"
                     /score="667.2"
                     /tool="antismash"
                     /translation="NGLKFFSKLQLPPGNWGCEYGGPMFLLPGVVIAWVVTETPIPQAY
                     AIEIKNYLMARANPVDGGWGLHSEGDSSVFGTSLNYTVLRLLGVDSEHPVMVQARGLLH
                     RLGGALNAPHWSKFWLAVLGVCDWEVVNPVPPEAWLLPDWVPVAPWRWWVHIRQVFLPM
                     SWIWSKRWTAAETDVVRALRRELFVQPWESIEWAAHRNDIAPTDNYHPKSWLLNSVNWI
                     LSNIWIPYLRPRSLATRAEDWVSKLIDMEDANSDYADLASVNGPLNMIVCYIRDGPDSY
                     SVRRHRERMEEFLWVNKEGMLANGTNGVQCWDTAFLIQAVWSAGLAEDAQFKPMLVQAL
                     EFLDRQQIRENCQDQGVCYRHVRKGAWAFSNRDQGYGVSDCISEALKAVIVLQKEADGY
                     PQLLEDQRIFDAVDTLLTYQNPSGGCASYEPTRGSEYLEMLNTAEVFGRIMVEYDYPEC
                     TSAVLTALVLFSKHWPDYRREEIQTFIQRGVDFIKRAQRPDGSWYGSWAVCFTYGTMFA
                     LECLRSAGETYENSEHVRRGCEFLLSKQREDGGWSESFQSCEQMTYIEHPTGSQVVQTA
                     FAIIAVLSVDYPDVEPIHRGVRMIMSRQQRNGEWLQEGIEGIFNKSCAITYPNYKFIFP
                     ILALGKF"
     PFAM_domain     complement(12297..12932)
                     /aSDomain="SQHop_cyclase_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF13249.9"
                     /description="Squalene-hopene cyclase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12040_0070"
                     /evalue="3.30E-32"
                     /label="AFUA_4G12040"
                     /locus_tag="AFUA_4G12040"
                     /protein_end="317"
                     /protein_start="105"
                     /score="111.9"
                     /tool="antismash"
                     /translation="IPQAYAIEIKNYLMARANPVDGGWGLHSEGDSSVFGTSLNYTVLR
                     LLGVDSEHPVMVQARGLLHRLGGALNAPHWSKFWLAVLGVCDWEVVNPVPPEAWLLPDW
                     VPVAPWRWWVHIRQVFLPMSWIWSKRWTAAETDVVRALRRELFVQPWESIEWAAHRNDI
                     APTDNYHPKSWLLNSVNWILSNIWIPYLRPRSLATRAEDWVSKLIDMED"
     promoter        13277..14115
                     /locus_tag="AFUA_4G12040"
                     /seq="TCGTCCAGCATCCGCCAGCGGGAGTAGTCTGTCTTGGCTAGTCGGTTCATGGC
                     GGAGGGTTGCAAGTACCAGCATGCCAGGTATACTCATCGACAGACAGAGAAACCAACAG
                     GCATAGGCCAGCTGTTTGCGACGACGAAATTGGGCCCCTATCTAGCCGATCTAGGCTAG
                     GGAGGTGCTCCGTAAACAATAGACAAAGTGGACACTAGTTTGTATCACATGCTACACAC
                     CTCGAGGTTCCTAAACAGGATTAAATACATTATACGGCTGGGCGGGCCTGAAGCCCCGT
                     TGACCACCCCCTCTGCTTATATGTGTTTTAACTCAGCCATCTCGAATCATAATGATATC
                     CTGCAAGGCTAGAGTCGGTTGTGCAAGTTGTCCAGAACGATACGAATCCGCCAGTGTTG
                     GCTAAAGGAAGGCGGCGTCAAGGGAACCGTTGATGATGACGTCACTTGCCACCAACCGC
                     GAATACCGGCGTTTACATAGAACACTCTGAAATCAAGTCAGGATGTGGAAAACAAGGCA
                     ATCATCTTTCTAGTGGAGGTATCAGCTATGCCTAACGCAGGGAAACCCTCTTGTGTACA
                     AGAAATCAAAATAGCAGACAGATCACCATGACAAGACATAAAGATTCACAACCGATGGG
                     AACTCCAGGATATGATGCGGACTCCGTAGACAAGGACAGATCATGATGCTCCCAAAAGC
                     ATGAGTGGGCAGCTCTAAAACTCCAAAGACACCGGACGGCGCAAGAGATCCATGCAATC
                     CGTGCAACTGAACCCAGTTCCCCCGAAAAAAAAAAAAAAAAAAATAATCATAAAGCAAG
                     CAGACACAGAATAACCCAG"
                     /tool="antismash"
     gene            complement(<14117..>14900)
                     /locus_tag="AFUA_4G12050"
                     /old_locus_tag="Afu4g12050"
     mRNA            complement(join(<14117..14572,14655..>14900))
                     /locus_tag="AFUA_4G12050"
                     /note="transcript AFUA_4G12050A"
                     /old_locus_tag="Afu4g12050"
                     /product="thermoresistant gluconokinase family protein"
     CDS             complement(join(14117..14572,14655..14900))
                     /EC_number="2.7.1.12"
                     /codon_start=1
                     /locus_tag="AFUA_4G12050"
                     /note="encoded by transcript AFUA_4G12050A; similar to
                     thermosensitive gluconokinase IdnK (26111609) [Escherichia
                     coli CFT073] PubMed = 9135111, 11468405; GO_component:
                     GO:0005737 - cytoplasm; GO_function: GO:0005554 - molecular
                     function unknown; GO_process: GO:0000004 - biological
                     process unknown"
                     /old_locus_tag="Afu4g12050"
                     /product="thermoresistant gluconokinase family protein"
                     /protein_id="EAL89588.1"
                     /transl_table=1
                     /translation="MLSAGERHQPPINTNAVVDASRTPVTKVSLNHNSTTSMRSETSKA
                     ENIQHIWVVTGPAGCGKSTVGRMLQQELGLPFLEGDDFHSQTNREKMGNGIPLTDEDRW
                     DWLISLRKAAIEALSPSQANNFHPPSGVVVACSALKQKYRDVMRVAAYGSPSVQIHFIY
                     LKLDKDILIERVKHRDPSHYMKSGMVHSQLQALEEPQGEWDALTVNADGPREEVQKTVL
                     QLVSEKLAEYQ"
     aSDomain        complement(join(14144..14572,14655..14744))
                     /aSDomain="TIGR01313"
                     /aSTool="tigrfam"
                     /description="therm_gnt_kin: carbohydrate kinase,
                     thermoresistant glucokinase family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_4G12050_0010"
                     /evalue="1.00E-52"
                     /identifier="TIGR01313"
                     /label="AFUA_4G12050"
                     /locus_tag="AFUA_4G12050"
                     /protein_end="225"
                     /protein_start="52"
                     /score="176.2"
                     /tool="antismash"
                     /translation="VVTGPAGCGKSTVGRMLQQELGLPFLEGDDFHSQTNREKMGNGIP
                     LTDEDRWDWLISLRKAAIEALSPSQANNFHPPSGVVVACSALKQKYRDVMRVAAYGSPS
                     VQIHFIYLKLDKDILIERVKHRDPSHYMKSGMVHSQLQALEEPQGEWDALTVNADGPRE
                     EVQKTVLQLV"
     PFAM_domain     complement(join(14150..14572,14655..14726))
                     /aSDomain="SKI"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01202.25"
                     /description="Shikimate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12050_0072"
                     /evalue="1.80E-13"
                     /label="AFUA_4G12050"
                     /locus_tag="AFUA_4G12050"
                     /protein_end="223"
                     /protein_start="58"
                     /score="51.0"
                     /tool="antismash"
                     /translation="GCGKSTVGRMLQQELGLPFLEGDDFHSQTNREKMGNGIPLTDEDR
                     WDWLISLRKAAIEALSPSQANNFHPPSGVVVACSALKQKYRDVMRVAAYGSPSVQIHFI
                     YLKLDKDILIERVKHRDPSHYMKSGMVHSQLQALEEPQGEWDALTVNADGPREEVQKTV
                     LQ"
     promoter        14850..15900
                     /locus_tag="AFUA_4G12050"
                     /seq="ACCGCATTGGTATTTATAGGCGGCTGATGCCTTTCCCCAGCAGAGAGCATAGT
                     GTGTAGAACAAAGGAAGAATAGCAGCTCAGACAGAAAAGAAAACAACGGTCGCAAAGAG
                     AGCCGCAGAGGGAACAAAGACTATGACGCTCTAGTGATACACGGAGCTCGGTGGCTGGT
                     CCGGATGGTTCAACCGGCTTTTGTGAGAGGTGTTGGGGTTGGTGAATGTATATAAAGGC
                     AGCGCTCTTGTGTCTCGAATGCTTTGAACTAGGTGAAATGCAGCAAACCAGGTCGTTGA
                     ACAGGCGATTGCAGGTCAAAGGCAATTGCAGTATCTTTCATGCAGATTATAAGGGGAAG
                     AAGAGAAAGAGACAAGGGAGTAATGGCTAAATAGAAAGGAAGAAATCCAAGCAGACGGA
                     TATTAAGTATCAAACCTGGGTCTGTGGGGACTTTCATGTCGAAAGCCGATCATGTAGGG
                     AAACATGACCTATTGTTTTCTTTTCGAGTCGGACTTACAAAAACATCGAATCATACAGA
                     CGTAACGGGAATTTTCCAACAACTTTTCAGACTGCAAAGTCCGAACAACTTCTACTGCA
                     ATGTTGGGTTGTTTCTCCATAGCCTAACCTCAAGGTGCCTTACAGAGTACGGAATATAG
                     ATTACAGCCAGCCGAGTGGGGGAATCAGTGAAACATATCACAAGGTGGGGGACATTCGA
                     GAAGAAAGGGGGTTCCGCTGGCTTGGGTATTAGTGGGAGATCGGATTCTTATTCTAGCT
                     TTGAAGACCCCTCACCATCGGAGAATGGGAGGAAAAGGGAAGAATAATTTCTATAATAA
                     TTCTAAAAAGCTGAAGCAGCTGAGTAGGTTGTATATCTCCATAGACAAATTGTAGAACT
                     GTATCTTTTGGTTGAGCATCAGCTATCTGCGAAATTACGTCCCAGTGTCATCCCATCGT
                     TTCATGATGTCACGGGTAGAAAAGAAGGTTGCCCTGCACCGGGGATCCGGGACTGATAC
                     AGCCAAGAATACAGATACAAGACTTATTGACACTCATCTCAAAACCCCCACACT"
                     /tool="antismash"
     promoter        16753..17803
                     /locus_tag="AFUA_4G12060"
                     /seq="TCAATCCGGGGAAACCCGCCAGTTTGAATGCAAACAATTCGCTGGCTAACACC
                     TTCAAGTTCCTAGCATTGAGTACTCTGTATTTATCCAAACCTTGTTGGAAATCGGAACT
                     TGGCAATTATCACGAGACTGGGTCTCAGCCTCAAGCAGGCAACATGTTCCGTGAAACAA
                     GGGCTCCGGAAATGTGTTTCCAGTTGCCTTACTTGGCAGGCTGGCGGATTTCTGCCCAA
                     TCCGTTCGTTCCAGTGCAGCTCGGGACAAAGAGAAGTATCGAACTTGTCGGGAACTGGA
                     TTATTTTCCGCGTCCTCTATCTTGGAAAGTTCCAGGTCGTACTGAAATTGGTTTTGAAT
                     AGCAGTCGTAGTATCATTACCCTCCATTTCGCAAAAGTATATTTCTCGGCGGATGGCAG
                     GGATGCGGTAGCAAATGCTGATACCCAGGTAGGTACTTGTACTTCTGTATTTTGAACGC
                     TAAAGACATGGAACACTGCACCAATTGTCTTTTTACCTTGGATCTTGATTCACGATAGT
                     TGGTCATCCGGAGCATTGTTCTCTAGCCATTTTGGCACGGACATGACATGAGCAAGTAT
                     GCATTTCATTGGTCAGCATCTGGAGTGCGCAACAATTTAGTGGTATGTTACAAGGGCTC
                     CCGGCACTGTAGATGTCGAGTTGCTTCATATTTTCTGACTCGGGGGGGAGAGTGACTCG
                     TATGTTCTTTGACTGTTAATCTACGAAATCCTCAATTACAGGATGTAACTGTTGATGGG
                     ATATGGGATAACGGCTACTATGATACCGCAATATTACGTAATCATCCATATGACAGGCT
                     AACTGTCAGGCAGTCGTGGATCGCCTTCTGCGGCCACGATCAACAACCTGGTGTAAGCT
                     TCAGCGAAGCTAAGCGGCATGGCAATTGTGGGATCCTATCTGATTTGATTGCAAGGACT
                     TCACGTGTGCACGAGTTCCAATCTAGTCTAACTCTCCTTACCCTGCCCAACCGGCCTCC
                     GAAATGACTTCTCTCTTTTTCTCCACTCCCGTCGACATTGACATCGTGCTCGAA"
                     /tool="antismash"
     gene            <17754..>19544
                     /locus_tag="AFUA_4G12060"
                     /old_locus_tag="Afu4g12060"
     mRNA            join(<17754..17973,18060..18532,18595..18619,18728..18844,
                     19330..>19544)
                     /locus_tag="AFUA_4G12060"
                     /note="transcript AFUA_4G12060A"
                     /old_locus_tag="Afu4g12060"
                     /product="Vacuolar protein sorting-associated protein 26,
                     putative"
     CDS             join(17754..17973,18060..18532,18595..18619,18728..18844,
                     19330..19544)
                     /codon_start=1
                     /locus_tag="AFUA_4G12060"
                     /note="encoded by transcript AFUA_4G12060A; GO_component:
                     GO:0005768 - endosome; GO_function: GO:0005554 - molecular
                     function unknown; GO_process: GO:0042147 - retrograde
                     transport, endosome to Golgi; GO_process: GO:0045053 -
                     protein retention in Golgi"
                     /old_locus_tag="Afu4g12060"
                     /product="Vacuolar protein sorting-associated protein 26,
                     putative"
                     /protein_id="EAL89587.1"
                     /transl_table=1
                     /translation="MTSLFFSTPVDIDIVLEDSDERQTVDVKLDKGRRERVPLYMDGES
                     VKGAVTVRPKDGKRLEHTGIKVQFIGTIEMFYDRGNHYEFLSLVQELAAPGELQHPQTF
                     PFNFKNVEKQYESYNGINVKLRYFVRVTVSRRMADVIREKDLWVYSYRMPPETNNPIKM
                     DVGIEDCLHIEFEYSKSKYHLKDVIVGRIYFLLVRLKIKHMELSIIRRETTGSPPNQYN
                     ESETLVRFEIMDGSPSRGETIPIRLFLGGFDLTPTFRDVNKKYSTRYYLSLVLIDEDAR
                     RYFKQSEITLYRQAPEIAATPQIAQQQQIQQQQLLQQQKQQQPLPEGSATAGPGRESYH
                     TQRVSAPAA"
     PFAM_domain     join(17769..17973,18060..18532,18595..18619,18728..18844,
                     19330..19331)
                     /aSDomain="Vps26"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03643.18"
                     /db_xref="GO:0006886"
                     /description="Vacuolar protein sorting-associated protein
                     26"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_4G12060_0073"
                     /evalue="1.30E-130"
                     /gene_ontologies="GO:0006886: intracellular protein
                     transport"
                     /label="AFUA_4G12060"
                     /locus_tag="AFUA_4G12060"
                     /protein_end="279"
                     /protein_start="5"
                     /score="434.4"
                     /tool="antismash"
                     /translation="FSTPVDIDIVLEDSDERQTVDVKLDKGRRERVPLYMDGESVKGAV
                     TVRPKDGKRLEHTGIKVQFIGTIEMFYDRGNHYEFLSLVQELAAPGELQHPQTFPFNFK
                     NVEKQYESYNGINVKLRYFVRVTVSRRMADVIREKDLWVYSYRMPPETNNPIKMDVGIE
                     DCLHIEFEYSKSKYHLKDVIVGRIYFLLVRLKIKHMELSIIRRETTGSPPNQYNESETL
                     VRFEIMDGSPSRGETIPIRLFLGGFDLTPTFRDVNKKYSTRYYLSLVLIDED"
     repeat_region   complement(19410..19464)
                     /note="microsatellite"
                     /rpt_type=tandem
                     /rpt_unit_seq="ctg"
ORIGIN
        1 ttaaagtctg tttgtgactt cgatgaactg ttccaagcat ttaagtgccg aaccgctttc
       61 gacggcccat cttgctcgtc gaacaccctc cttccagcga ccaccgcccg gaccacgttc
      121 ggtaatcacc ttgccatcat caccagggcc catgttactg gtgtcggctt cacaaatgcc
      181 cgaaatcacg aggagggcgg caacattaat caagacgaat gtaaggatgg gatcatccgg
      241 aggcagctcg tttcgcaaga tactcatgat cttggctgcg ttttctttcg gcatctttct
      301 accatagact gcgcttagag gatgtgcggg cagaccaaaa tcagacgggt gaagctggaa
      361 ggtttctatc ttgaccaaag tccggggaat attttcgtcc tcgtcacagg agcagtcctc
      421 atcagggccg tcgtagtcgg gattggggta tcccgtaagt ttccagcagt ttgttggacc
      481 cgcgcaactg atttcatcca ggtcctccgc accacagaca acaagggcct tcgtcacccc
      541 actggagcgc aaggcttcag cgaacacggg gcccaggctc tgataagcca caccgaccac
      601 tctcgcttcc agcgcccagt cgaccgggtt tgccaatggg cccattagat tgaagatagt
      661 tcgcaggccc aagccccgac gcactgggtt ggcgtacatc ataccggggt ggaaattggg
      721 ggcgaacagg aacgcgtagc tcgttgcttc gtagacttgg gccaggttct cggcagtaac
      781 tgcggagatc ttcggaggaa ctggggagat cgcgttcagg acgtcggcag agccagagaa
      841 tgaagtttgt gcgcggttgc cgtgcttggc catcataagg agcggcgagg cgataataga
      901 ggcagtcgtt gaaatgttga atgtagaatg tgaatcacca ccggtcccaa caatatcgca
      961 ctggaccaaa acaaatttgt cgaataagca agacagtcaa gctatcggct ctggtttcga
     1021 ttcactcacc aagccgcctc catagtttcc ttccttcttc ccacgagctt tgatggcttt
     1081 ttgcaaagag ctcttctcga tctggctagc tgcctctctc atgcgaagtg aacataatgc
     1141 aatgacctgt gcatctcgat cttttccagt agaatgcaaa agagttaaaa gagcggccgt
     1201 ctggatggcc gatagacgat cttcaaagat caatgcaaat gctgaagcga tttcggcggg
     1261 atcaacagga acctgtgtag tagggtaggc gagtttctga aggaggggtg agatcgaaac
     1321 ctgattaggc ttctggtcaa attcatgcgc agacaacatg gtgacctgag tagagcgcta
     1381 ctcttcaaga cacttgaaaa tgactccaaa tgtcagcaat gacaaaggaa ggtggaagta
     1441 gcaaacagcc cctcagcttg tatcaccgga ggagtcatcg gcactcggca gaatctcacc
     1501 gcccacctaa tggactatac cggatcgagg acatcgtcca ttgtttctcc cagattttgg
     1561 tttctttgcg tgccttcaat cattcatcgg ccaaggttat cggcgccaac cattgcgcga
     1621 gactatcacg ccctgtgttt cctgagggcc tgcactgata tcatcacact cgcagataga
     1681 caaatcttac acttccgatt cacgatgccg ccccggttac gactcgctaa tggacgcatt
     1741 tcgttccgcc gccagagagt cctatgtcaa ttcgaattac cagtcgctgc tcgttatgca
     1801 agcaccgcaa ctagagcaac gactccggcc gcatctattg aacagatgac atcttctatt
     1861 cctccacttg ctagatatcc cccttctcag cctccctctc atcgcaatcc tgagtatcga
     1921 cgatcacagc ttctccgaca gtacacatcg ctgatccgca ctacacctct catggttctt
     1981 ttccagcacg ataaccttcg gtcggtggaa tggaccgcaa ttcgacggga actgagcaag
     2041 gccatgcaga aagttgatga gaagattgcc gctgacggac ggcaagctca gccactggcg
     2101 ccgcacatca aggtgcaaat cgtgcagacc agcatcttcg aggtcgcttt gcgcattgtc
     2161 gaatatttcc gcccagatag gaccacagtg gcaaatgcca aacctcccag agccgtcgat
     2221 cccgttacac agacctccgc tgagatccca ccgtcgggat ccaaggacga cccgactttg
     2281 acccatgacc tctcccgtgc ggcccatgac gctgtgatgt acatgaaagg caagcatgaa
     2341 ctctcagcgc ttctcgtggg tcccgttgca gtcctttcta tcccacaggt gtctcccgag
     2401 cacctgaaag ccgctatgtc ggttcttgcc cccaaggaga ctggcttccc tgctcccact
     2461 aggagggcta acccggcatg gcatgaacct cctgtccaaa atggattgca gaaattgagc
     2521 ttgctggctg ctcgagtaga tggtcaggtc ttcgatgtcg accagacgaa atgggtcggc
     2581 agcatcgaag gtggtatgga tggcttacgg tctcaactca ttatggctct gcagagcatg
     2641 ggatctagca ttacgaatgc cctggcaggc gctggtaaga gcctctattt cactctcgag
     2701 agcaggagga gtgttctgga agatgagcag aagggccctg agggtgacaa gaacgaatct
     2761 taacaacata gcaaaccttg tctggtcatc catgtataat attttttttt gtacttctct
     2821 caattagatt tcctcagaaa aacctctcgg ttacattact caatcttgaa cagcatatct
     2881 ttgatcaact aggatccatt ccgtgagatc tgtttttgat cctcctgctg tcctcttact
     2941 gtgtaattta ttttccttct tgaacatggg cgcatgtacg aattacattt attgaaatat
     3001 cataatgacc tatagaatca tcgatgggaa atgatagcta catgatcagg cttcccaggt
     3061 cggccagggg gcgcgtgaaa gcacaaatca agcgtcgtta gtgttcctgc tcctctctca
     3121 tctgtctcat cttcagctta gcattcatgc caacaatgca acgcacaagg tcccagtcgc
     3181 cttcgtggcc aacccagtcc gtaacaagaa taccagtcga ccagtcaccg tccgggtgac
     3241 tgtgtctccg gcagagatag tcaacagttg ccgggttcag ctttgctgca atcttctcgg
     3301 gccacgtccc caccttccag aagttgcttg cactgaggaa atttatatag aatggatgcg
     3361 ctttgctagc ttcgggatcc gggagggcac cgaacgggta acagtgcccg ctggagcgct
     3421 cacagtgctc cgttacatat ttgattttga catcgatgtt cttcgtctcg aggacctcgt
     3481 agaagtcctg gatgcagagt tgaccactgc tgcaggtagc gtttggagta ttatctgccc
     3541 aatcgcttcc gtctatgccc cagccgcggc cgtcgtgttc atgctttagc tcttcaatga
     3601 tgttgaaccg gcgaagcagg acgactttcc cgcgcacctc gcccagagta gggattttgg
     3661 gttctgtgta ccaccggcta tctggacgag cataatggtc gcgcacaatc cgactcaatt
     3721 gttcatcggt atggtttcct gggccttctc gcttcagaga gatgatgagc gtctcggatg
     3781 gattctcatt gaggaactca ttaacgtctc gcatcagatc gcgaaagtac ttgttgcccg
     3841 tcaaggagat ggggaacacg ctgtgcacta ggataagctc atctttggat gggtcctctg
     3901 ggaactgggg ctgcacacgg atgtcgaaga aacggacacc atttcgaagc tgttcgcgcg
     3961 gactgacagc ttggcagcgg acagacgggg ccgcgacatg gcacgtagga gaattgtgtg
     4021 ttcctggtat ggatagcgag gagagcaatg tgctatcttt gagctctccc atccatgctt
     4081 gcagattggc cgaggagtag atcgcaaggt gggattcagg cgtcacgtag acgccagtga
     4141 agcgaaatcg aggattatca cacaacgcct tcattccggc agactccgtc gtaggaaccg
     4201 gtgtctgaat ctgatgtcgc tctccctcgg cttcaaaggt ccagcgcagg cgctctttgt
     4261 ccgaatcgat gaatgcacga acttcggtct ggactgtctg gaaaggctcc acgtgaatat
     4321 catactcttc atgagcaaat ggttcattgt catcagtaat cgcggcgaca gtctcattgg
     4381 tgcgagtgac attgcttaga attcgagtaa aattcctggc caaggaatgt atgtcatctc
     4441 gaggatcctt atgggggtga aaacgctcaa tgagcttgag gattattggg gttgtggtaa
     4501 ggttgcgaat cgtcaagtgt tcggccacca ttgtgcgaca agccagtgct caattgaaca
     4561 gtctatcacg tacagcagaa gccagtcccg aaatgcaaaa tatgaaccag atggatagga
     4621 gaacgagtag ggagtgagaa gagaatactg ccgcctgctc ttctcggccc tcagagggtg
     4681 cttagccctg acaagactag aagattaggt tgcaccaatg atggttcgat cctccgcaat
     4741 gggatctcgc agtcccacgt tcatcgtgcc agtagctgga accctaagca tcatcttaag
     4801 acaacacaca agacacacca aattgtactt ggagaacggg tacttttacc cgttctgagc
     4861 tggagactga gcattattga acagatagca acttggctgg cactaaagtc agactcagag
     4921 actcaatcac agcacaaggc aatagatgaa atagtggtgg tgggttgtca ttgctcagct
     4981 ccaccgtgat gagataatcg tggggtttca caaaataatg actaacagag gggaaggtag
     5041 gcgagtcgtg gagataaaaa tctcgaccat gcacatcatt gtcgcgattt tcgaatactc
     5101 catagctctg cttggtaatg aaaaaaagta tttgcatgga ttgcagcaaa ttttcttgct
     5161 gaacaagtag atatccctgc tctaatcaaa cgagcactca gtgaatattg ggtaccgccg
     5221 gcttgagttg aagcagggtt tgactcagct tgagtgactc gcaaaatcga atcggattcg
     5281 attcagctac gatcttttgc tcaacaagga ggaaacaatg gaatcgagct gttcaacaag
     5341 gcaccattcc tgaagctttc agtatttgag ttcggatgag aagacggacc gagccacaag
     5401 aatactttct cgattgataa tgcggagtaa atcacgtggg gtgacgctgt gctcggttac
     5461 tatcggcgat ggggagcaat aatgcggaga gaccctgtgt agtcctcctc ctactaatag
     5521 ggacaattcc atgatgtctc acagtttttc ttctttggaa aactacccta tctctatatt
     5581 cccattctcg attgcttcat aattgactat gagctttttg cgctgcaaca gaggtgttct
     5641 gggggccctc aggtcctctc ggcctcagag ggtcatccca accatcccat cgtcaaaaat
     5701 atcaatacct cgacggagtt ttcatcctgc attacccttt tgggccataa aatctcaaat
     5761 attgaaggat gtgggcgaag gtgtttcttt cctacgcaac ttgcatgtct gtcactcaat
     5821 tgctcattca aattctctac gcagggatca ccgaagtcca aataattcag tggtacgtcg
     5881 aagaaggcgc tcacatagaa gagtggaagc cactgtgcca gtatcagtct gataaagcag
     5941 tggatgatgt gagcaagttc ttctctatcc cgctatctac ctatctgacc atctaccaat
     6001 ctagataact tcgagatacg aaggagtagt caagaaactc cactttcaag cagatgacac
     6061 tgtacccaca ggaatggtat gcatgttcat gtacagttga aaggcgagga caatccgcgt
     6121 ctaacattat gttcttctca ggcgctctgt gatatagaag tcgaagatgg caaatatcca
     6181 gatgatcaca cgcctactga acccaaaccc gagcaattac agccagaccc cgttgctgca
     6241 gatactcttt ctgtacagtc aacagcatcg actccgttgc ccccttcaca ggccaatgag
     6301 accactgttg aagccccaag gtcaaagtat gcctctctcg ctaccccagc agtccgtggg
     6361 ctgctgaaga cttacaatgt tgatattctt gacgttaaag ggacggggaa ggatggtcgt
     6421 gtccttaaag aagacgtgaa tagatttatt gccatgcgcg acgcatcagc acaagcgcgt
     6481 tctgtggcac ctgccagtca gcaaacagaa accacggtta acctgacacc gatccaatca
     6541 caaatgttca agaccatgac ccgctctctc actatcccgc acttcctcta tgcggatgag
     6601 ctcaagatca acgacattac agctctaagg aagaagctgg catctgaccc caaagatccc
     6661 aaaaaggtca cctttctccc tttcgttatc aaggctgtgt cccttgcttt gaatgagtat
     6721 ccgcttctta acgctaaggt ggacttgagc attcctgaaa agccgaaact aatcatgcgg
     6781 ccgaaacata acatcggagt tgcattggat accccacagg ggttgatcgt tccgaacatc
     6841 aaagatgtcg caaaccggac aattatggaa attgcagcag aaattaagcg gctaagtgca
     6901 ctgggcaaag agggtaaact cacgcccgct gacttgagtg gtggcacgat aactgtctca
     6961 aacatcggca acatcggcgg cacctacgtt ggaccagtga ttgtaccaac tgaagtggct
     7021 attctggggg ttggaaaatc aagaacagta ccagtctttg atgatgctgg gcaggtcacc
     7081 aagggcgagc tagtgaattt tagttggagt gcagaccata gagttgtgga tggggccact
     7141 atggcaagaa tggccaacaa ggttcgcgag tttatcgagt cgccagagtt gatgctcttg
     7201 aatttgaaat agagcaagag tggttcttcc gtcacagtga tagcaggttc taatatagca
     7261 gttatagagt taacctgaca aagcgattga aagtcaacag gtaatctgct tctgagtctg
     7321 ttgtgatgga gtcatgaaca ccaagtccta ctattgtgtt ttgatgaata gatgtttatc
     7381 ccaagaccgt tggcagtgaa ttctcatttt cttttaaatt ctgtgttcat atcttctttc
     7441 atctgtttgc tcaaggctgt gcgtactggt atcaacaacc cctcctcata gctctcagcc
     7501 tctcaccact ccccactcac aacctccaac ctcaattttc tcctttgcac tctcattctt
     7561 ttgattcata ctttgcttgc cctattgctg ttactttatg agaagtgtaa ccctcagtct
     7621 atcttgtagc ctttgtttct gtcctgaata gtgacagcaa acagtcaaga tgggtacaaa
     7681 aggacttctc ttcatccgct gccgcggcag atacttcgtc atctggaatc agcttgacag
     7741 ctatcctgag ggactcggag atgctattgt tcatgaaata ccaactgatc ctgagggcta
     7801 ccgcagtagg agaaacacca tgattctgga tgctgtgcac actcactgac acatttgttt
     7861 tcgctagatt ggctgaattc gatgagggag atgtattccc gttctgcaca gaagttcgaa
     7921 gatcagatcc tcacggtgga tgtcaaaatc gagcaagacg atcttaccat cagtgagcgt
     7981 catgcaatga gttatctggc tatcgatgac cgccttatat atgctccaat tcagacgatc
     8041 atggacagat tctccaatga tctcatcatt gaatggactt acaccataga ccttgaccgg
     8101 gagatgttcg ccgttgatga tgccgcatgc ttcaagctgt tcaatatacc ccgcggggga
     8161 cggtggatcc gatatctcgc tgaggacgcc cagcggcgca gaaagctgag tgataataca
     8221 cccaaggata ttattgctga tatctcatgg aaaccaaaca ttaatcccaa cttgagggtt
     8281 ttgggtgaag ctctcaacat tgagcctctc tcgcttaccg attttgctgc cgaaactatg
     8341 ctccgcttgg acttggatac cactgttgac aagcaaatga tgcctgtccg catcaacttt
     8401 ctgatgacca cgtttttgca gatgtgtagg gtgtatcgga agattcttga tcgctttgtc
     8461 cttgcttggg agcccagctg ttttatgttc agggaaatgg cgttcgcagt gctgtcgctc
     8521 gctgctggag aagtgttttt cgaattctct gaagtcctag atgcgaagta tagggaaaat
     8581 ggctattact tgcttccaga ttccaggact ccaaaatacc atacgaggat gctcccgcgg
     8641 ttcatacatg agagtcacct tcctggcatc gagcctggat cagcaccgaa gagcactagc
     8701 ttctggtttc acgacgttct cgttcatctt aattctagac ttgatttaga tgatgtcgaa
     8761 gaagcatcag tggtagcggt ggtaaatgat ggactcgatc aaggatacga agagttctac
     8821 gccatggtac tctcgattct agacgttgtt ctgatccgcg ttcagaaggg acgggatgga
     8881 aagccataca tcagaaggtc tccgctcatg gctctgtttg agtttactga agagaactct
     8941 ggatatgctc atggcccccg tactcgtctg tctcagtccc agcagggtct caacaaacaa
     9001 gacagtcacg gcgccaaaca gaaagacaca tccccaggag aaagcgatgc tgcagaagag
     9061 gacggtgctg cttccgatat atcagcggac ccagcggccg cgggttattt caccttcatg
     9121 ctgatgtacc acttcttcaa tgcggctgcc gctgagaggc ttgctggtac gaggtctctt
     9181 ctgtttccca atgagatctt gtccttgatc atggactttt cagatatgcg tacatatttg
     9241 gcgcttgcac aatcatctgc gttctgccac gagctaagcc atcacaagct ccggctgaac
     9301 gatgaatacg ctgtgattgg gagtggcgaa gattctgaga cctttgtcct agaagacttg
     9361 cattcgggga agaagattca ttctaagctc agcatgtacc aaaagaattg gcttggccat
     9421 ccaatcgcag atggactcaa attgagtcct gttataggcg tcacgaatac aaaaagactc
     9481 agtatcatgg atgacgtgac cattcagtta tcggacgtga cgccaaaaga tccagtgtgg
     9541 tctgaggcag aagaaggttc ttcgcagtaa gtggtacatc tcatatgtaa tttgtcagga
     9601 tatcagtaaa agctgatata tcgtagagaa cagcatggct ggtctttccc tccaaatgag
     9661 gaagatggtg acttgatttt caatttaccg aatgatgcgt atctcggcgc tgtcgagacc
     9721 gcttggggac gatacctgtc caagctagca agagacgctg gtgagcccga ctcagagttc
     9781 ttcagtacta tgctccgcaa cagactgtac cgctgtcttc tgcctcctgg ataccgtgaa
     9841 ttagggatgg agcccttcct ttgcagcggt ttccacgcat tcttccgcca cgagcgtgac
     9901 aaaactccag aagagtggga acagaccctt cagtatgtcg ctcgtcagct ttccaagctt
     9961 gaagtccgcc ccagagagag attccggaga tggggtcatc ccgttattgt ggccttttcg
    10021 gcaagagtca agctgttcta ttatgtcttt catcgtgagg tcaagcctcc gatttgctcg
    10081 aatccgaaat catacaccgt tgaaatcgct gacaagtgca ctgaccccaa ttctggcaga
    10141 cggcttgtcc agctcattgc cggagaagat ccaattgatc tgaaagacga tgatggcagg
    10201 atgaggtttg aaagctgaat catatctctc tgtaaaaaca gctcactgca gtacaatcca
    10261 tacaccgaac agtttgagca ggaggctgag gtggatgatg aagacgacaa tggagaggac
    10321 agaggagaag acgatgaagg gcatgaagat tgacgacagg tgggagtcag attgagtcag
    10381 ccatgctgcg tctttaggat cttgatgctc gcctatctgt tcagctgctt gcggtctatt
    10441 ctgtttggta tcattatatc ggtctcttct tccgtaaacc attctttgtg ggagtcgata
    10501 aatcacagag aggaatggat aatagttact agatgtatga atgaccagca ggttgtaaag
    10561 cattctgagc gaatgtgtca attgactata catagctaag gaagcaagat aaaaggaaga
    10621 aaaattgaaa aacgtacaac agccaggacg agcattagcg ctggaggaac tttagaaggt
    10681 cgttgacccc tttaagcaat ctcttctgcc tcgctcagta gcagcacaaa gaacttgaga
    10741 ccatgatgca gactacatta ccttcagata aggcctctgt aggcccgttg gcaagctata
    10801 ataatagggt taggggcgat tggggccctg cctctaggtg cacgcagcag atgacaaaag
    10861 tatatgacat gcttccttat tatccggccc gtctgtgata tatacgaggt ctgctccaag
    10921 agaagggaaa actcaagctt cagtttctga atttacggag tccttggttg aagaagggaa
    10981 cccgagaatt actgctttat tgatacatcc attgtggccc acctcctaca cgaggtgggg
    11041 gtattttctc ccaaatttgc ctaatgcaag aatcgggaag atgaatttgt aattcgggta
    11101 tgtgatagca cagctcttgt taaagatgcc ttcgataccc tcctgtagcc attccccgtt
    11161 tcgctgctgt ctagacataa tcatgcgaac tccacggtgg ataggttcaa catcgggata
    11221 gtcaacgctc aggactgcga ttattgcgaa tgcggtctga acaacttgag atcccgtagg
    11281 atgctcgata tacgtcattt gttcgcagct ctgaatgggt tagttttcaa gtatcttatc
    11341 gaagcatagg ggtagtgtag tggcttgttg atttcagtac tcacctgaaa gctttctgac
    11401 catccaccat cctcgcgttg tttcgacagt agaaactcgc aacccctgcg gacatgttca
    11461 ctattctcat aagtttctcc agctgatctc aggcattcca gagcaaacat cgtgccgtat
    11521 gtaaagcata ctgcccagct tccataccaa ctgccatcag ggcgttgcgc ccttttgata
    11581 aaatccactc ccctttggat aaatgtctgt atctcttctc gccggtagtc aggccagtgt
    11641 ttggagaaca agaccaaagc tgtcagcaca gcgcttgtgc actcaggata atcatattca
    11701 accataatac gtccaaagac ctctgctgtg ttcaacattt cgaggtattc acttccccgg
    11761 gtcggctcgt aggatgcaca accgcccgat gggttctgat aagtgagcaa ggtgtccacg
    11821 gcatcaaaga tcctttggtc ttcaagcagc tgtggatatc catcggcctc tttctgaagc
    11881 acaataacag ccttcagcgc ctctgaaatg cagtcgctca ccccataacc ctggtcgcga
    11941 ttgctgaaag cccaggcccc cttacggaca tgacgatagc aaacgccctg atcctgacaa
    12001 ttctcgcgga tctgctgtcg atctaggaac tccagcgcct gtaccagcat gggcttgaac
    12061 tgcgcgtctt cagctagacc agccgaccac acagcctgta tcagaaacgc tgtatcccag
    12121 cattgtacac cgttcgtccc gttggcgagc atcccctctt tattcaccca gaggaattct
    12181 tccatgcgtt cccggtgacg acgcacagag taggaatcgg gcccatcgcg gatatagcaa
    12241 acaatcatgt tcaagggtcc attcacggat gctagatcgg cataatctga attcgcatcc
    12301 tccatgtcaa ttagtttact gacccagtct tccgcccgtg tagccaggct tctcggtcga
    12361 aggtaaggta tccagatatt cgacaggatc caattgactg agttcaacaa ccacgacttt
    12421 ggatgataat tatcagtcgg agcaatgtca ttgcggtgtg ccgcccactc gatgctctcc
    12481 cacggctgga caaacagctc ccgtcgcagg gccctcacaa cgtccgtttc cgcggccgtc
    12541 caccttttag accagatcca cgacatcggg agaaagacct gccggatatg cacccaccat
    12601 ctccatgggg ccacaggtac ccagtctggc agcagccatg cctctggagg aaccggattg
    12661 acaacctccc agtcacacac ccctagaact gccagccaga acttcgacca gtgcggcgca
    12721 ttcagagcgc ctccgagccg gtggagaaga cctcgcgcct gcaccatgac cgggtgctca
    12781 ctgtccaccc caagaaggcg caacacggtg tagttcaggg acgtgccaaa cacagagctg
    12841 tcgccttcgg aatggagacc ccatcctcca tcgaccgggt tcgcgcgcgc catcagataa
    12901 tttttgatct ctatcgcata ggcctgcgga atgggcgtct ccgtcaccac ccacgcaatc
    12961 accaccccgg ggagcaagaa cattggcccg ccatattcgc agccccaatt ccccggtgga
    13021 agctgtagtt tcgagaagaa tttcaggcca ttaatcgcac tgtccaacgg tgaagtagca
    13081 gtaggaagat ccgggagatc ctattccatc atcaaaatca gaattggttg cctggagcac
    13141 gcgccatggc ggcagggtta atcgcctatg gtggagatac cagaggaagc cctaaataat
    13201 acttatcagc cagtgtttgg ggccatgtcc gagccgcttc atcatcgtcg agataatgcc
    13261 atgtgtgctt tccatcttcg tccagcatcc gccagcggga gtagtctgtc ttggctagtc
    13321 ggttcatggc ggagggttgc aagtaccagc atgccaggta tactcatcga cagacagaga
    13381 aaccaacagg cataggccag ctgtttgcga cgacgaaatt gggcccctat ctagccgatc
    13441 taggctaggg aggtgctccg taaacaatag acaaagtgga cactagtttg tatcacatgc
    13501 tacacacctc gaggttccta aacaggatta aatacattat acggctgggc gggcctgaag
    13561 ccccgttgac caccccctct gcttatatgt gttttaactc agccatctcg aatcataatg
    13621 atatcctgca aggctagagt cggttgtgca agttgtccag aacgatacga atccgccagt
    13681 gttggctaaa ggaaggcggc gtcaagggaa ccgttgatga tgacgtcact tgccaccaac
    13741 cgcgaatacc ggcgtttaca tagaacactc tgaaatcaag tcaggatgtg gaaaacaagg
    13801 caatcatctt tctagtggag gtatcagcta tgcctaacgc agggaaaccc tcttgtgtac
    13861 aagaaatcaa aatagcagac agatcaccat gacaagacat aaagattcac aaccgatggg
    13921 aactccagga tatgatgcgg actccgtaga caaggacaga tcatgatgct cccaaaagca
    13981 tgagtgggca gctctaaaac tccaaagaca ccggacggcg caagagatcc atgcaatccg
    14041 tgcaactgaa cccagttccc ccgaaaaaaa aaaaaaaaaa aataatcata aagcaagcag
    14101 acacagaata acccagtcac tggtattccg ccagcttctc cgacaccaac tgaagaacgg
    14161 tcttctgaac ctcctcgcgg ggaccatcag cgttgacggt cagcgcatcc cattcgccct
    14221 ggggttcctc gagagcctgc aattgcgagt ggaccatgcc gctcttcata tagtgggagg
    14281 gatcacggtg cttgacgcgc tcgatcagga tgtccttgtc cagcttgaga taaatgaagt
    14341 ggatctgaac cgagggggac ccgtaggcgg cgacgcgcat gacgtctcga tatttctgtt
    14401 tgagggcgga acaggcgact acaacgccgg acggagggtg gaagttgttg gcttgcgaag
    14461 gggagagggc ctcgatggcg gctttgcgca aggagatgag ccagtcccag cggtcttcgt
    14521 cggttagagg aatgccattg cccattttct cccggttggt ctgtgagtgg aactgtatgg
    14581 gtgcgtgtta ggtcaacttg cgcattttgc cgggaagccg taggaagaaa tatcgcgtgg
    14641 atgcaagtac ttacatcatc tccttcgagg aagggcaaac ccagctcctg ctgcaacatc
    14701 cgtccaacag tacttttccc gcatcccgcg ggcccggtga cgacccagat atgttggatg
    14761 ttctcggctt tggatgtctc tgaccgcatt gaggtggtcg agttgtgatt cagagaaact
    14821 ttggtgactg gagtccgaga ggcatccaca accgcattgg tatttatagg cggctgatgc
    14881 ctttccccag cagagagcat agtgtgtaga acaaaggaag aatagcagct cagacagaaa
    14941 agaaaacaac ggtcgcaaag agagccgcag agggaacaaa gactatgacg ctctagtgat
    15001 acacggagct cggtggctgg tccggatggt tcaaccggct tttgtgagag gtgttggggt
    15061 tggtgaatgt atataaaggc agcgctcttg tgtctcgaat gctttgaact aggtgaaatg
    15121 cagcaaacca ggtcgttgaa caggcgattg caggtcaaag gcaattgcag tatctttcat
    15181 gcagattata aggggaagaa gagaaagaga caagggagta atggctaaat agaaaggaag
    15241 aaatccaagc agacggatat taagtatcaa acctgggtct gtggggactt tcatgtcgaa
    15301 agccgatcat gtagggaaac atgacctatt gttttctttt cgagtcggac ttacaaaaac
    15361 atcgaatcat acagacgtaa cgggaatttt ccaacaactt ttcagactgc aaagtccgaa
    15421 caacttctac tgcaatgttg ggttgtttct ccatagccta acctcaaggt gccttacaga
    15481 gtacggaata tagattacag ccagccgagt gggggaatca gtgaaacata tcacaaggtg
    15541 ggggacattc gagaagaaag ggggttccgc tggcttgggt attagtggga gatcggattc
    15601 ttattctagc tttgaagacc cctcaccatc ggagaatggg aggaaaaggg aagaataatt
    15661 tctataataa ttctaaaaag ctgaagcagc tgagtaggtt gtatatctcc atagacaaat
    15721 tgtagaactg tatcttttgg ttgagcatca gctatctgcg aaattacgtc ccagtgtcat
    15781 cccatcgttt catgatgtca cgggtagaaa agaaggttgc cctgcaccgg ggatccggga
    15841 ctgatacagc caagaataca gatacaagac ttattgacac tcatctcaaa acccccacac
    15901 tataccacaa taggcaggct gtgtactgca aaagcagttt taccatgtta ttttcaggcg
    15961 cctctctgaa ctcaatggaa gaccatacag ttcaatattc aaaggacaag gaatgcagac
    16021 gaaactcttc aagatttact cagagatgat ctccagggac cagagaccag gatgctgtgg
    16081 ctagcatggt ttgatggaaa taaggtagtg gcctgacctg agaaccttct aatatctatc
    16141 cgttgactgt ctactggcaa gaaattcttc gatattgatt gtaatttgga atgcaattga
    16201 tggtaggtaa ggccgaatgg cgtacacata cctagtattt acactgtaat cggattaatc
    16261 ccttacgcaa tcttcgagat cttcaatact acctatcaac aatagaaagt gggagatttt
    16321 aatcaaagcg caaaggatct atccctagct acggagtaca ctctgtaaaa cgctgctcat
    16381 tcacttctaa cgcatccctg atgatagagc atggctgtac aacacttcaa tctgtcaatg
    16441 tttgatcccg tggacaggcg gacaaacaat aatgagtgca ttatgggcgg gatagtactc
    16501 cgcacttctc gaggtacttt tggcgtctca gctctgagag gcgctcagca gacaatcttc
    16561 gttcaaacaa gggttatggt tcaaaagagt gaagctgcaa cccgataccg ccttttcttc
    16621 aaactgtcaa gcgtcgaccc tcctccactc aacagtcaaa gtcgtgtatc aacttcgaca
    16681 ggagtgctgg ccatgtgccc caccgcctaa tctgaatgat cttgggtcct tgtggcttgc
    16741 agggggacgt ggctcaatcc ggggaaaccc gccagtttga atgcaaacaa ttcgctggct
    16801 aacaccttca agttcctagc attgagtact ctgtatttat ccaaaccttg ttggaaatcg
    16861 gaacttggca attatcacga gactgggtct cagcctcaag caggcaacat gttccgtgaa
    16921 acaagggctc cggaaatgtg tttccagttg ccttacttgg caggctggcg gatttctgcc
    16981 caatccgttc gttccagtgc agctcgggac aaagagaagt atcgaacttg tcgggaactg
    17041 gattattttc cgcgtcctct atcttggaaa gttccaggtc gtactgaaat tggttttgaa
    17101 tagcagtcgt agtatcatta ccctccattt cgcaaaagta tatttctcgg cggatggcag
    17161 ggatgcggta gcaaatgctg atacccaggt aggtacttgt acttctgtat tttgaacgct
    17221 aaagacatgg aacactgcac caattgtctt tttaccttgg atcttgattc acgatagttg
    17281 gtcatccgga gcattgttct ctagccattt tggcacggac atgacatgag caagtatgca
    17341 tttcattggt cagcatctgg agtgcgcaac aatttagtgg tatgttacaa gggctcccgg
    17401 cactgtagat gtcgagttgc ttcatatttt ctgactcggg ggggagagtg actcgtatgt
    17461 tctttgactg ttaatctacg aaatcctcaa ttacaggatg taactgttga tgggatatgg
    17521 gataacggct actatgatac cgcaatatta cgtaatcatc catatgacag gctaactgtc
    17581 aggcagtcgt ggatcgcctt ctgcggccac gatcaacaac ctggtgtaag cttcagcgaa
    17641 gctaagcggc atggcaattg tgggatccta tctgatttga ttgcaaggac ttcacgtgtg
    17701 cacgagttcc aatctagtct aactctcctt accctgccca accggcctcc gaaatgactt
    17761 ctctcttttt ctccactccc gtcgacattg acatcgtgct cgaagacagc gatgagcgcc
    17821 agacagtgga cgtgaagctc gataagggcc gccgcgagcg agttcctctt tacatggatg
    17881 gggagtctgt caagggtgct gttacggttc gaccaaagga tgggaagcga ttagagcaca
    17941 caggcatcaa ggtgcaattc attggcacaa tcggtatggg accctgccca ttcaaagacc
    18001 gcagcactta tcaccactgg tggtcgagac atgaactgac caagtatctt gctaagcaga
    18061 gatgttctac gatcgaggca accattacga attcctttcg ctggtgcagg aacttgccgc
    18121 tcccggagag ctgcaacacc cacagacatt ccctttcaac ttcaagaacg tcgagaaaca
    18181 atacgaatca tacaatggta tcaatgtgaa gctgcggtac tttgtgcggg tgacggtctc
    18241 gaggcggatg gcagatgtga ttcgcgagaa ggatctctgg gtctactctt atcgcatgcc
    18301 cccggaaacg aacaacccaa tcaagatgga tgtcggtatc gaagactgcc tgcatattga
    18361 gtttgaatac tccaaatcca agtatcacct gaaagatgtc atcgtgggac gtatctattt
    18421 tctcctcgtg cggctgaaga tcaaacacat ggaactatcc attattcgac gtgagacgac
    18481 agggtctcct ccaaatcagt acaatgagag cgagacactg gtacggttcg aggtaggcca
    18541 gcccgttgat tggcccaaaa caggggatgc ctgctaacgt tgttgttctg atagatcatg
    18601 gacgggtcgc cttcgcgagg tgagttgcat ccggttgaag ttgcttcatg ccaatactgc
    18661 tggcacccca cgaaaagcaa tatgtcattt gaacaaatgg gaagagtttc ctgctgatca
    18721 tgaacaggag agacaatccc tattcgtctg ttcttgggtg gtttcgatct gacacccacc
    18781 ttccgtgatg tcaacaaaaa gtactccaca agatactatc tgagcctagt attgatcgat
    18841 gaaggtaagc agaacaaaaa aatgaaagca cttgcttgtt cggatatttt ctgcattggc
    18901 ctggactgcc cgatcgattc cctatggcga accaagtgtc gtttgtatga cttggaaagc
    18961 cggtcaccat tgtcgcggcg ttgtttgctg cctgcattgg tacctgaggt ttccatatgt
    19021 tcaacttgcc caatgttatc ccacggtatc ccacctagac atttcaatag ccgatcggct
    19081 attgaaatca cctcggacca gtcatggcgg tcagtcgact cggaccggct gacttgcgat
    19141 ctcattccga acggcaaaat cccccacgct aagccacact tggatgatcc cactcgcgtg
    19201 gcggccccac taggccccgg gttttcgtaa tttcatatgg ttttgtttcg gaacccggct
    19261 gtattcttca gttttttgca tcccacaact gcagtttgaa acgtactgac tcgaactcct
    19321 tgtacctaga tgcccgtcgg tacttcaagc agtccgagat tactctctac agacaagctc
    19381 cagagatcgc agcgacccct caaatcgctc aacagcaaca gatccagcag cagcagctcc
    19441 ttcagcaaca gaagcagcaa cagcccctac cagaagggtc agccacggcc ggacctggac
    19501 gtgaatcata tcacactcag agagtctctg ctcctgccgc ttagcctgta ggctgagtat
    19561 gtcgcatggc gtctcgctta acgtttctat ttcaaggaag ttgttgagat ttggcggcat
    19621 cttctactcc gtacatatac cctatttgac tctgtatctg taccttgtgc ttattttgat
    19681 tcgttgccat cggataaact ggccctgtag ttcgacggtc aacggttgaa tttttaagtg
    19741 aagtagttcg ctgtgcccac cgatgattga gaatgcgact ctcgctttcc acaaatactc
    19801 atctatacaa atatgcacga tcgaggtcta tttgagatga tctctagcga aaaatataaa
    19861 ctatacaaat taaacgtcat tgccgacccg ttctaagact gctccaagaa cctggagaac
    19921 ctctccgtca tcattttccc ttcccgcgac ctgcaccgct tttataacga gagggtataa
    19981 ccattccaga tgtttcttgt gatgtttatt tccggcttgg cttgagtcgc cggacgacat
    20041 gattactgtc ctgattatag gcggaggagg aatggcagtt ggttcgcttc gcaaatcgat
    20101 catgccgcgg agaagatgta gcagtgcctt gcgcgccggc gtgggctgcg gcatgagtcc
    20161 gcggagtggc tgatccgcga tgtatgcctt cagggacatg gcgcatcgga gtatgagata
    20221 cggggagaca gcgcgcgaga gcagaacacg ggctgtcgtt tgctccgtat cacttgtctc
    20281 ttttctggat gtatcatcat cgttgggctg ggaggctgat gcgagctcaa atagcatgtc
    20341 gatcagaatg tatgccattc gagcacgtgg ggttggcggt gggtcaaacg ttcggccagg
    20401 ccggatatta tatagatcct gcagaggctc cttatccgaa tacttgatag gagcgccaaa
    20461 acgctgttgc tggtagatga aagaggagtc gaataacgta cgagagaatt ggcgtcgaat
    20521 attgtctgaa atgatggacg cgcctagaga tgggatgatg atggttttga gcttgttcat
    20581 agcattgatg tcgaaggttt cgtctgcgtg gacttttgtt gtggggattg aacgggttcg
    20641 ataacctttc gcagaggcaa taccgttcgc aatgtctacc acgcacttcc agaaccgcga
    20701 gatctcttcc agatttgcat actcgtattg cttttcgatg tatggaactg ccacatggag
    20761 gatatccagc actgcagtgg ttgatttctg ccataaactg ggatctcggt cttttcccgg
    20821 ccactcgtat ctttgaacaa ttgggttccc aagatgttcc aaggcacaag atagagagcc
    20881 attggagaag atatcttcct tgataccaaa ggtagcaata taccagccca ggagctctac
    20941 agcacttttc gagaacgcaa taaaagttgg ccttctcgaa tccgaatcta gggaccactt
    21001 tgtcaatgcg gaatcaacga agtcagcaag acagaaaacg atctttggct gggccacctg
    21061 cttgtctgaa catagcagtt tcaaacagtc aatgataatt gcttgtacat ccgaaacccg
    21121 atccacgtcc ggcgaataag gagaggagac ggagttccaa gcgaggaggc gcaaatgatg
    21181 gagaatatgc tcaatatggt cattccctag atcgtcctta tagagggcat acaactgctg
    21241 aaatgcctgc aagtatgcag atgatgcatc ctgatttggg tgtcctaggt caattaagtc
    21301 ctccctggga gcaggatggc cagcaaccca cagcgaccaa gcgagctcga gagccttctt
    21361 gctcagatta tttgtcacct gtgcccggag aaggatgttt gccagactgg agaataccgc
    21421 ttcatttagc tccaggaagt ttgagctgat aagcttgtac aaatatccca agagatgttc
    21481 ccaggaagcg tcaaaggcac tgtctccaac aataggccca aaaaaagtag ttatcagatt
    21541 ggcaatcccc ttgatcatga caactgccgt ttctatccag gaatggacca cctcagagcc
    21601 tctggccttc tccgctgccc gagaatttgc gagttcaagt tcgatggttt caaccattag
    21661 gaacaaaaca cggttcagac acagacgcca tgccttgggt gaaagttgtt gtccgtacgc
    21721 atcgaaaatt cttagaaggg tctgaatcgc gcagtttcgg atctccagcc tgctatccct
    21781 cgcaaggctt acaatcctaa gcagaagcag cagccacagc gcatttcgtg agaccgaggg
    21841 ttcatcacct cttgcaagag ccgaaagtgt ctcctcgctg actgagagtt cgacatgaga
    21901 ctcaatgcag aattcctcaa tttgcccttg tagaaaatca gatatattcc agaaagatga
    21961 tgtcgttgtc aatgagatgt tgaagtcctc ttgctgtaaa gcgaaacggg ataatgaatt
    22021 cacgaggtcc aaccgacatt ggcgtggcaa gagagcgata aaatcagaag cgactaactg
    22081 tagagatttg tatgcagcac gaacgagccg aggcgaatcg gcaatcgagc gtgtatcacg
    22141 caccctgcta gacgtatctc ctgccgctgt cgcactctcg ccgtttgaaa tgtccccgaa
    22201 cacactggat atcagactga agacaagcgt ccatccatca gtgaaagact ctgcgtactg
    22261 ctccagaata ctctttaacg tctccaggct ttgctcatga atctctatga tggaggtaga
    22321 gagtggtaac cctggcatgc aagcgttaac cgaatagagc gtcgagactt gcatgttcag
    22381 agtttccagg tttctgatat gacgcgcgtt tcggactgaa tcatcagcat cgtctccctg
    22441 tttcatagtc tcaaatacga catagctgag tacaccattc gcttttagac gaagtctctg
    22501 gcttatctct gggtttgcgg cggtggcaat caaccgctcg atgagcagct tccagacgcc
    22561 gcggtctggg ttggccaacg acgacaagcg ttcaagattt gcttgggcga gctcttttgc
    22621 tttgtccaag acaaatttca gttcttcatc ccgcattctg gacttttcga tcacaaagga
    22681 cacaccccgg ttgttccccc gtggccgacc gatatgcttt tgcgacggcg aggagttagg
    22741 agtcccgggt atcttttcag acggcccatc ttttgctggt ccttcagtta tgccggagag
    22801 gtcaaggaga gcaatcagca gaccgccgaa cgaatcgctc ggatagtcac cagtgctctc
    22861 gaacaatttt gcagaggctg cctcaacagc tgtaatttct gacccgaggt tggctttaga
    22921 catatcgcct gacacatctc ccgcattatg aacaaggtta tgtgttttgc tggaggccat
    22981 actgatgagt aagtctacat cctgcagcgt tccgagaatg atcgaccatg ccggctggtc
    23041 taaagtagga ccaagggcaa tccccaggtt cagaagagca cggaggcaca gcagatttct
    23101 ggtgcttagt gacaatgaag caatttccgc agatgctctc ggaccgtcct tgcgtttttc
    23161 atccatagcg ggaatgctgt gggaatctga ggcagctgca gtcgaagcac cagccatctc
    23221 agctggcatt gtagccttcg ctagagtagt cagaaaagcg tcccgcggaa cggagagtct
    23281 gagaagaccg gcaacatgag ccagcttctg aaaagatcga acaaggt
//
