LOCUS       CM000170               42706 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 2, whole genome shotgun
            sequence.
ACCESSION   CM000170
VERSION     CM000170.1
KEYWORDS    WGS.
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
REFERENCE   1  (bases 1 to 4844472)
  AUTHORS   Nierman,W.C., Pain,A., Anderson,M.J., Wortman,J.R., Kim,H.S.,
            Arroyo,J., Berriman,M., Abe,K., Archer,D.B., Bermejo,C., Bennett,J.,
            Bowyer,P., Chen,D., Collins,M., Coulsen,R., Davies,R., Dyer,P.S.,
            Farman,M., Fedorova,N., Fedorova,N., Feldblyum,T.V., Fischer,R.,
            Fosker,N., Fraser,A., Garcia,J.L., Garcia,M.J., Goble,A.,
            Goldman,G.H., Gomi,K., Griffith-Jones,S., Gwilliam,R., Haas,B.,
            Haas,H., Harris,D., Horiuchi,H., Huang,J., Humphray,S., Jimenez,J.,
            Keller,N., Khouri,H., Kitamoto,K., Kobayashi,T., Konzack,S.,
            Kulkarni,R., Kumagai,T., Lafon,A., Latge,J.P., Li,W., Lord,A.,
            Lu,C., Majoros,W.H., May,G.S., Miller,B.L., Mohamoud,Y., Molina,M.,
            Monod,M., Mouyna,I., Mulligan,S., Murphy,L., O'Neil,S., Paulsen,I.,
            Penalva,M.A., Pertea,M., Price,C., Pritchard,B.L., Quail,M.A.,
            Rabbinowitsch,E., Rawlins,N., Rajandream,M.A., Reichard,U.,
            Renauld,H., Robson,G.D., Rodriguez de Cordoba,S.,
            Rodriguez-Pena,J.M., Ronning,C.M., Rutter,S., Salzberg,S.L.,
            Sanchez,M., Sanchez-Ferrero,J.C., Saunders,D., Seeger,K.,
            Squares,R., Squares,S., Takeuchi,M., Tekaia,F., Turner,G., Vazquez
            de Aldana,C.R., Weidman,J., White,O., Woodward,J., Yu,J.H.,
            Fraser,C., Galagan,J.E., Asai,K., Machida,M., Hall,N., Barrell,B.
            and Denning,D.W.
  TITLE     Genomic sequence of the pathogenic and allergenic filamentous fungus
            Aspergillus fumigatus
  JOURNAL   Nature 438 (7071), 1151-1156 (2005)
   PUBMED   16372009
  REMARK    Erratum:[Nature. 2006 Jan 26;439(7075):502. Lafton, Anne [corrected
            to Lafon, Anne]]
REFERENCE   2  (bases 1 to 4844472)
  AUTHORS   Nierman,W., Wortman,J., Pain,A., Anderson,M.J., Arroya,J., Hall,N.,
            Barrell,B., Fraser,C. and Denning,D.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-MAY-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.2
            Run date    :: 2025-07-23 12:25:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 4767514
            Orig. end   :: 4810220
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..42706
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="4"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..42706
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42706
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[15000:27706](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="15000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(15001..27706)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="15000"
                     /product="indole"
                     /protocluster_number="1"
     mRNA            <559..>1725
                     /locus_tag="AFUA_2G17930"
                     /note="transcript AFUA_2G17930A"
                     /old_locus_tag="Afu2g17930"
                     /product="integral membrane protein"
     gene            <559..>1725
                     /locus_tag="AFUA_2G17930"
                     /old_locus_tag="Afu2g17930"
     CDS             559..1725
                     /codon_start=1
                     /locus_tag="AFUA_2G17930"
                     /note="encoded by transcript AFUA_2G17930A; similar to
                     sll1376 (GI:1653341) [Synechocystis sp. PCC 6803]"
                     /old_locus_tag="Afu2g17930"
                     /product="integral membrane protein"
                     /protein_id="EAL94092.1"
                     /transl_table=1
                     /translation="MPLPVFAVSFAYLYLTGSLVFDTIHWLLHKWSKSQWKILRWLSYC
                     HQFHHLYYNRSLKFNERYARHNSWIALPLEMLCKVFGSMAGWLLARHLMADDKQNISTA
                     ALLVACAFEIIRTLVVIAISGRDSNHIAFDTVPKDHNWLFVGPEYHALHHVYPERYMGS
                     MVKVFDWVAGTAYSLRNKRVVLTGGSGAFGCAIEKQLLSEGVKDIKKLHFGKDWTHNDV
                     SGVGKSLEESDILILAHGTKGRDAMDANCKSTMRLIELFLRRKAAEDIQQTKTVPEIWY
                     VGSEIEIHPAWGNPELQRYSASKRAFLPYARALYDHPRIIYRHIVPAAFESRMGKAIVS
                     PDWAARVALWWIRRGAHYVPVTYTGLAFLNFFKFLLLVRPSTRPDWEL"
     mRNA            complement(join(<3835..3977,4030..4177,4292..4373,
                     4448..4646,4666..>4990))
                     /locus_tag="AFUA_2G17940"
                     /note="transcript AFUA_2G17940A"
                     /old_locus_tag="Afu2g17940"
                     /product="MAK1-like monooxygenase, putative"
     gene            complement(<3835..>4990)
                     /locus_tag="AFUA_2G17940"
                     /old_locus_tag="Afu2g17940"
     CDS             complement(join(3835..3977,4030..4177,4292..4373,
                     4448..4646,4666..4990))
                     /codon_start=1
                     /locus_tag="AFUA_2G17940"
                     /note="encoded by transcript AFUA_2G17940A; similar to
                     PIR:S70702: maackiain detoxification protein 1 [Nectria
                     haematococca]"
                     /old_locus_tag="Afu2g17940"
                     /product="MAK1-like monooxygenase, putative"
                     /protein_id="EAL94093.1"
                     /transl_table=1
                     /translation="MNVLCRWDKSMRPAIDSIRAAISSFDYYDSNGELRDCLPYAPGDL
                     LNVEVVQMSGLIDLLYGKAKDCGIDLRFGAIVCDYWESEGNAGIVLENGHKVAADCVIA
                     ADGWGTITGKDVAPYSTGAAIYRSHFDSREIRDDPEANWILDSTGRADHANMYLGKDTT
                     LLVGTVGKGKNVKSKDLIIPGSSLQTLSMSWNWSRTGQWLLAMRPMLCTPISVKEPTWP
                     LKMQQSSLLAWSSVERKTCLSVCGLWRNYARSEFRWSRQLRSRRWRGSSMQTGILTKLM
                     GNQPMIHAQPGYCDMTV"
     mRNA            join(<7866..7911,8379..>8683)
                     /locus_tag="AFUA_2G17950"
                     /note="transcript AFUA_2G17950A"
                     /old_locus_tag="Afu2g17950"
                     /product="conserved hypothetical protein"
     gene            <7866..>8683
                     /locus_tag="AFUA_2G17950"
                     /old_locus_tag="Afu2g17950"
     CDS             join(7866..7911,8379..8683)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G17950"
                     /note="encoded by transcript AFUA_2G17950A"
                     /old_locus_tag="Afu2g17950"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL94094.1"
                     /sec_met_domain="PhyH (E-value: 3.2e-07, bitscore: 27.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPPCKGAYAPAQFHTSCTKSDQAIGATRLIPGSHLWNYSVPFSED
                     DVVWADQQPGDTLIILGSVFHVGSWNTTDRVRLVLSTSAVRGKFRGEENGYLTYSKDHI
                     SRLPVNLQKFFG"
     PFAM_domain     8384..8563
                     /aSDomain="PhyH"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF05721.16"
                     /description="Phytanoyl-CoA dioxygenase (PhyH)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G17950_0087"
                     /evalue="3.90E-06"
                     /label="AFUA_2G17950"
                     /locus_tag="AFUA_2G17950"
                     /protein_end="77"
                     /protein_start="17"
                     /score="27.4"
                     /tool="antismash"
                     /translation="TKSDQAIGATRLIPGSHLWNYSVPFSEDDVVWADQQPGDTLIILG
                     SVFHVGSWNTTDRVR"
     mRNA            complement(<9525..>10655)
                     /locus_tag="AFUA_2G17960"
                     /note="transcript AFUA_2G17960A"
                     /old_locus_tag="Afu2g17960"
                     /product="NADPH dehydrogenase Oye3, putative"
     gene            complement(<9525..>10655)
                     /locus_tag="AFUA_2G17960"
                     /old_locus_tag="Afu2g17960"
     CDS             complement(9525..10655)
                     /EC_number="1.6.99.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G17960"
                     /note="encoded by transcript AFUA_2G17960A; similar to
                     widely conserved NADPH oxidoreductase containing flavin
                     mononucleotide (FMN), homologous to Oye2p with slight
                     differences in ligand binding and catalytic properties; may
                     be involved in sterol metabolism; Oye3p (GI:6325086)
                     [Saccharomyces cerevisiae]; GO_function: GO:0003959 - NADPH
                     dehydrogenase activity; GO_function: GO:0050662 - coenzyme
                     binding; GO_process: GO:0008152 - metabolic process"
                     /old_locus_tag="Afu2g17960"
                     /product="NADPH dehydrogenase Oye3, putative"
                     /protein_id="EAL94095.1"
                     /transl_table=1
                     /translation="MREEPSSAQLFKPLKVGRCHLQHRMIMAPTTRFRADGQGVPLPFV
                     QEYYGQRASVPGTLLITEATDITPKAMGYKHVPGIWSEPQREAWREIVSRVHSKKCFIF
                     CQLWATGRAADPDVLADMKDLISSSAVPVEEKGPLPRALTEDEIQQCIADFAQAARNAI
                     NAGFDGVEIHGANGYLIDQFTQKSCNHRQDRWGGSIENRARFAVEVTRAVIEAVGADRV
                     GVKLSPYSQYLGMGTMDELVPQFEYLIAQMRRLDVAYLHLANSRWLDEEKPHPDPNHEV
                     FVRVWGQSSPILLAGGYDAASAEKVTEQMAAATYTNVAIAFGRYFISTPDLPFRVMAGI
                     QLQKYDRASFYSTLSREGYLDYPFSAEYMALHNFPV"
     PFAM_domain     complement(9630..10631)
                     /aSDomain="Oxidored_FMN"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00724.23"
                     /db_xref="GO:0010181"
                     /db_xref="GO:0016491"
                     /description="NADH:flavin oxidoreductase / NADH oxidase
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G17960_0088"
                     /evalue="1.70E-88"
                     /gene_ontologies="GO:0010181: FMN binding"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /label="AFUA_2G17960"
                     /locus_tag="AFUA_2G17960"
                     /protein_end="342"
                     /protein_start="8"
                     /score="297.3"
                     /tool="antismash"
                     /translation="QLFKPLKVGRCHLQHRMIMAPTTRFRADGQGVPLPFVQEYYGQRA
                     SVPGTLLITEATDITPKAMGYKHVPGIWSEPQREAWREIVSRVHSKKCFIFCQLWATGR
                     AADPDVLADMKDLISSSAVPVEEKGPLPRALTEDEIQQCIADFAQAARNAINAGFDGVE
                     IHGANGYLIDQFTQKSCNHRQDRWGGSIENRARFAVEVTRAVIEAVGADRVGVKLSPYS
                     QYLGMGTMDELVPQFEYLIAQMRRLDVAYLHLANSRWLDEEKPHPDPNHEVFVRVWGQS
                     SPILLAGGYDAASAEKVTEQMAAATYTNVAIAFGRYFISTPDLPFRVMAGIQL"
     mRNA            join(<11443..11860,11913..12109,12169..>12426)
                     /locus_tag="AFUA_2G17970"
                     /note="transcript AFUA_2G17970A"
                     /old_locus_tag="Afu2g17970"
                     /product="ergot alkaloid biosynthetic protein A"
     gene            <11443..>12426
                     /locus_tag="AFUA_2G17970"
                     /old_locus_tag="Afu2g17970"
     CDS             join(11443..11860,11913..12109,12169..12426)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /locus_tag="AFUA_2G17970"
                     /note="encoded by transcript AFUA_2G17970A; similar to
                     ergot alkaloid biosynthetic protein A, orfA (GI:57864916)
                     [Claviceps purpurea]"
                     /old_locus_tag="Afu2g17970"
                     /product="ergot alkaloid biosynthetic protein A"
                     /protein_id="EAL94096.1"
                     /transl_table=1
                     /translation="MTILVLGGRGKTASRLSLLLDNAGVPFLVGSSSTSYVGPYKMTHF
                     DWLNEDTWTNVFLRASLDGIDPISAVYLVGGHAPELVDPGIRFINVARAQGVNRFVLLS
                     ASNIAKGTHSMGILHAHLDSLEDVQYVVLRPTWFMENLLEDPHVSWIKKEDKIYSATGD
                     GKIPFISADDIARVAFSVLTEWKSQRAQEYFVLGPELLSYDQVADILTTVLGRKITHVS
                     LAEADLARLLRDDVGLPPDFAAMLASMETDVKHGTEVRNSHDVKKVTGSLPCSFLDFAE
                     QEKARWMRH"
     aSDomain        join(11446..11860,11913..12109,12169..12414)
                     /aSDomain="TIGR03649"
                     /aSTool="tigrfam"
                     /description="ergot_EASG: ergot alkaloid biosynthesis
                     protein, AFUA_2G17970 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_2G17970_0007"
                     /evalue="2.00E-118"
                     /identifier="TIGR03649"
                     /label="AFUA_2G17970"
                     /locus_tag="AFUA_2G17970"
                     /protein_end="287"
                     /protein_start="1"
                     /score="393.0"
                     /tool="antismash"
                     /translation="TILVLGGRGKTASRLSLLLDNAGVPFLVGSSSTSYVGPYKMTHFD
                     WLNEDTWTNVFLRASLDGIDPISAVYLVGGHAPELVDPGIRFINVARAQGVNRFVLLSA
                     SNIAKGTHSMGILHAHLDSLEDVQYVVLRPTWFMENLLEDPHVSWIKKEDKIYSATGDG
                     KIPFISADDIARVAFSVLTEWKSQRAQEYFVLGPELLSYDQVADILTTVLGRKITHVSL
                     AEADLARLLRDDVGLPPDFAAMLASMETDVKHGTEVRNSHDVKKVTGSLPCSFLDFAEQ
                     EKARW"
     mRNA            complement(join(<13132..13753,13786..14024,14316..>14471))
                     /locus_tag="AFUA_2G17980"
                     /note="transcript AFUA_2G17980A"
                     /old_locus_tag="Afu2g17980"
                     /product="cytochrome P450 monooxygenase, putative"
     gene            complement(<13132..>14471)
                     /locus_tag="AFUA_2G17980"
                     /old_locus_tag="Afu2g17980"
     CDS             complement(join(13132..13753,13786..14024,14316..14471))
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G17980"
                     /note="encoded by transcript AFUA_2G17980A; identical to
                     cytochrome p450 (GI:66853773) [Aspergillus fumigatus Af293]
                     PMID: 15933009 similar to SP:Q12645: Pisatin demethylase
                     (Cytochrome P450 57A1) [Nectria haematococca mpVI];
                     GO_function: GO:0016491 - oxidoreductase activity;
                     GO_process: GO:0008152 - metabolic process"
                     /old_locus_tag="Afu2g17980"
                     /product="cytochrome P450 monooxygenase, putative"
                     /protein_id="EAL94097.1"
                     /sec_met_domain="p450 (E-value: 2.2e-35, bitscore: 118.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLLLTFTLPVVTLLLAHIIRSWFRLRHIPGPFWAKITDLWREHHY
                     IKGDYGDRPMAPYFAIPSLLGMESAMDQIQQELEDQICRRVTIDVVLWMRLFSLESLHW
                     IAFSNKLGYLSEGKDTDGILSILQSKFIGLAGQLCGWIHRTTLRFHFPKSCTGTAVAPS
                     QRKASHRDLLAHFMDASQKNPETLEERGVLGATISTIFAGTDTTGTSLTFFMYYLIKHP
                     AALARLQEELDSAVRSGNLSYPPKWVEVSTLKYLQAVFKETLRLHSTARMSLYRVVGPE
                     GLDLCGERLPSGTNLGCFGYTAHRNEPIYGRDAALFRPERWIEASNDTLLSMERASL"
     PFAM_domain     complement(join(13168..13753,13786..13967))
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G17980_0089"
                     /evalue="2.90E-34"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_2G17980"
                     /locus_tag="AFUA_2G17980"
                     /protein_end="327"
                     /protein_start="71"
                     /score="118.8"
                     /tool="antismash"
                     /translation="DQIQQELEDQICRRVTIDVVLWMRLFSLESLHWIAFSNKLGYLSE
                     GKDTDGILSILQSKFIGLAGQLCGWIHRTTLRFHFPKSCTGTAVAPSQRKASHRDLLAH
                     FMDASQKNPETLEERGVLGATISTIFAGTDTTGTSLTFFMYYLIKHPAALARLQEELDS
                     AVRSGNLSYPPKWVEVSTLKYLQAVFKETLRLHSTARMSLYRVVGPEGLDLCGERLPSG
                     TNLGCFGYTAHRNEPIYGRDAALFRPERWIEASN"
     mRNA            complement(join(<15001..15124,15179..>16365))
                     /locus_tag="AFUA_2G17990"
                     /note="transcript AFUA_2G17990A"
                     /old_locus_tag="Afu2g17990"
                     /product="dimethylallyl tryptophan synthase FgaPT1"
     gene            complement(<15001..>16365)
                     /locus_tag="AFUA_2G17990"
                     /old_locus_tag="Afu2g17990"
     CDS             complement(join(15001..15124,15179..16365))
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_2G17990"
                     /note="encoded by transcript AFUA_2G17990A; similar to
                     L-tryptophan dimethylallyl transferase DmaW (GI:32402652)
                     [Neotyphodium coenophialum]"
                     /old_locus_tag="Afu2g17990"
                     /product="dimethylallyl tryptophan synthase FgaPT1"
                     /protein_id="EAL94098.1"
                     /sec_met_domain="dmat (E-value: 8.4e-111, bitscore: 367.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTKTDAQGRHPQETATHAATTDEEVQDQWRAPFEVLSRTLVFQHE
                     DHRLWWERAASKLATYLRLAKYSVGSQYQHLLMFYSVYAPNLGPWPNDKRDNVHWVCGI
                     CPGGENLEISMNYQQGAKCTVRIAAETITPAAGTDKDPFNLTAEKKMIEDLKALQPNLN
                     FTWFNHFQREVLVPEEVALNNDEIISKVPFKNQRLHGLDLSEGAFMLKSYFMPAIRSAI
                     TGVENTQIMFESIRKLNLKNANFISALSTLEDWMVPTNGRFMEYWDGISYDAVDACKAR
                     IKIYTGIRMKSIEHARDVWTLGGRLQGEDIEKGFDLVARLWRRLMDEEPSTCEMKYWMQ
                     WVWELRTDVPFPVPKLYFSVAAAEDHYVSDTVVEILDYLGWDDLVQTHRALMDEAWSLG
                     QTTKSYLAFSYISVTFHSIKGPYITTYGNPSGPRPVF"
     aSDomain        complement(join(15034..15124,15179..16269))
                     /aSDomain="TIGR03429"
                     /aSTool="tigrfam"
                     /description="arom_pren_DMATS: aromatic prenyltransferase,
                     DMATS type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_2G17990_0008"
                     /evalue="2.30E-110"
                     /identifier="TIGR03429"
                     /label="AFUA_2G17990"
                     /locus_tag="AFUA_2G17990"
                     /protein_end="426"
                     /protein_start="32"
                     /score="367.6"
                     /tool="antismash"
                     /translation="FEVLSRTLVFQHEDHRLWWERAASKLATYLRLAKYSVGSQYQHLL
                     MFYSVYAPNLGPWPNDKRDNVHWVCGICPGGENLEISMNYQQGAKCTVRIAAETITPAA
                     GTDKDPFNLTAEKKMIEDLKALQPNLNFTWFNHFQREVLVPEEVALNNDEIISKVPFKN
                     QRLHGLDLSEGAFMLKSYFMPAIRSAITGVENTQIMFESIRKLNLKNANFISALSTLED
                     WMVPTNGRFMEYWDGISYDAVDACKARIKIYTGIRMKSIEHARDVWTLGGRLQGEDIEK
                     GFDLVARLWRRLMDEEPSTCEMKYWMQWVWELRTDVPFPVPKLYFSVAAAEDHYVSDTV
                     VEILDYLGWDDLVQTHRALMDEAWSLGQTTKSYLAFSYISVTFHSIKGPYITTY"
     PFAM_domain     complement(15205..16230)
                     /aSDomain="Trp_DMAT"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11991.11"
                     /db_xref="GO:0009820"
                     /db_xref="GO:0016765"
                     /description="Tryptophan dimethylallyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G17990_0090"
                     /evalue="2.60E-90"
                     /gene_ontologies="GO:0009820: alkaloid metabolic process"
                     /gene_ontologies="GO:0016765: transferase activity,
                     transferring alkyl or aryl (other than methyl) groups"
                     /label="AFUA_2G17990"
                     /locus_tag="AFUA_2G17990"
                     /protein_end="387"
                     /protein_start="45"
                     /score="303.6"
                     /tool="antismash"
                     /translation="DHRLWWERAASKLATYLRLAKYSVGSQYQHLLMFYSVYAPNLGPW
                     PNDKRDNVHWVCGICPGGENLEISMNYQQGAKCTVRIAAETITPAAGTDKDPFNLTAEK
                     KMIEDLKALQPNLNFTWFNHFQREVLVPEEVALNNDEIISKVPFKNQRLHGLDLSEGAF
                     MLKSYFMPAIRSAITGVENTQIMFESIRKLNLKNANFISALSTLEDWMVPTNGRFMEYW
                     DGISYDAVDACKARIKIYTGIRMKSIEHARDVWTLGGRLQGEDIEKGFDLVARLWRRLM
                     DEEPSTCEMKYWMQWVWELRTDVPFPVPKLYFSVAAAEDHYVSDTVVEILDYLGWDDLV
                     QT"
     mRNA            join(<17095..17683,17751..>17947)
                     /locus_tag="AFUA_2G18000"
                     /note="transcript AFUA_2G18000A"
                     /old_locus_tag="Afu2g18000"
                     /product="short chain dehydrogenase/oxidoreductase CpoX2"
     gene            <17095..>17947
                     /locus_tag="AFUA_2G18000"
                     /old_locus_tag="Afu2g18000"
     CDS             join(17095..17683,17751..17947)
                     /EC_number="1.-.-.-"
                     /NRPS_PKS="Domain: PKS_KR (9-127). E-value: 5.7e-10. Score:
                     31.3. Matches aSDomain:
                     nrpspksdomains_AFUA_2G18000_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G18000"
                     /note="encoded by transcript AFUA_2G18000A; identical to
                     oxidoreductase (GI:66853775) [Aspergillus fumigatus Af293]
                     PMID: 15933009 similar to oxidoreductase (GI:4499846)
                     [Claviceps purpurea] PMID: 10071219; GO_component:
                     GO:0005634 - nucleus; GO_component: GO:0005737 - cytoplasm;
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor; GO_process: GO:0006563 - L-serine metabolic
                     process"
                     /old_locus_tag="Afu2g18000"
                     /product="short chain dehydrogenase/oxidoreductase CpoX2"
                     /protein_id="EAL94099.1"
                     /transl_table=1
                     /translation="MASVESRIIAITGGASGIGAATCRLLAERGAAVLCVCDISPKNFD
                     DLKISIKKINPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRN
                     TPTIAEEVDEEWTRIMNTNLNGVFYCTREEVRAMKGLPATDRSIVNVGSIASVSHMPDV
                     YAYGTSKGACAYFTTCVAADAFPLGIRINNVSPGVTNTPMLPQFAPMAKTFEEIEESYK
                     KEGLSLIEAEDVARTIVWLLSEDSRPVFGANINVGACMP"
     PFAM_domain     join(17116..17683,17751..17779)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00106.28"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18000_0091"
                     /evalue="1.40E-43"
                     /label="AFUA_2G18000"
                     /locus_tag="AFUA_2G18000"
                     /protein_end="206"
                     /protein_start="7"
                     /score="148.8"
                     /tool="antismash"
                     /translation="IIAITGGASGIGAATCRLLAERGAAVLCVCDISPKNFDDLKISIK
                     KINPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRNTPTIAEE
                     VDEEWTRIMNTNLNGVFYCTREEVRAMKGLPATDRSIVNVGSIASVSHMPDVYAYGTSK
                     GACAYFTTCVAADAFPLGIRINNVSPGVTNTPMLPQ"
     aSDomain        17122..17475
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_2G18000_PKS_KR.1"
                     /evalue="5.70E-10"
                     /label="AFUA_2G18000_PKS_KR.1"
                     /locus_tag="AFUA_2G18000"
                     /protein_end="127"
                     /protein_start="9"
                     /score="31.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="AITGGASGIGAATCRLLAERGAAVLCVCDISPKNFDDLKISIKKI
                     NPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRNTPTIAEEVD
                     EEWTRIMNTNLNGV"
     CDS_motif       17125..17196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_2G18000_0001"
                     /evalue="1.20E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AFUA_2G18000"
                     /protein_end="34"
                     /protein_start="10"
                     /score="24.4"
                     /tool="antismash"
                     /translation="ITGGASGIGAATCRLLAERGAAVL"
     mRNA            join(<18600..18836,18911..19027,19093..19195,19255..19323,
                     19378..19983,20064..>20491)
                     /locus_tag="AFUA_2G18010"
                     /note="transcript AFUA_2G18010A"
                     /old_locus_tag="Afu2g18010"
                     /product="cytochrome P450 monooxygenase, putative"
     gene            <18600..>20491
                     /locus_tag="AFUA_2G18010"
                     /old_locus_tag="Afu2g18010"
     CDS             join(18600..18836,18911..19027,19093..19195,19255..19323,
                     19378..19983,20064..20491)
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G18010"
                     /note="encoded by transcript AFUA_2G18010A; contains a
                     Cytochrome P450 domain; GO_function: GO:0016491 -
                     oxidoreductase activity; GO_process: GO:0008152 - metabolic
                     process"
                     /old_locus_tag="Afu2g18010"
                     /product="cytochrome P450 monooxygenase, putative"
                     /protein_id="EAL94100.1"
                     /sec_met_domain="p450 (E-value: 1.2e-32, bitscore: 109.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDFLQRILGILSSEDVAPALFASSISVLFLILSYQVLYPPSKYSA
                     FPTINGTRWLALSNRRILAEFVTDAQGLMRNGLEKYDIFRIISSIGPMTILHPKYTDEI
                     HNDRQLNFMAVLAKEMFPNYPGFDLFREGTDGSTVLQDAVKFGSSRCLGKSTQLLSDET
                     STLLQKLWGDEPEWHEVTAKSSVHDIIAHLSALLFYGPELCSHKEWLEVTDEYASVGFL
                     AARQLRLWPPILRPIAQWFLPACRRLRYLASRTRGLIEPVIAARQKEKAICYSHGRQPP
                     VYDDAIEWTERAAKGRPYDAAMSPLLFSINALHTTTDLLTQVILDLSTQPDLIVALRQE
                     ILSVKPQQNGWKNASLNQLLLMDSAIKESQRLKPTESILMRRYAMDDLTLADGNKIPKG
                     TVLGIPIFGMRDPKIYVDPDMYDGYRFQKMRDKPGFENKCQLVSTSPWHLGFGHGIHAC
                     PGRFLAAVQVKIILCYIVAKYDFKLAGGAPPKVQSVGIELISDTEARLAVRRRQEMVIG
                     LE"
     PFAM_domain     join(19557..19983,20064..20404)
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18010_0092"
                     /evalue="1.40E-31"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_2G18010"
                     /locus_tag="AFUA_2G18010"
                     /protein_end="491"
                     /protein_start="235"
                     /score="109.9"
                     /tool="antismash"
                     /translation="PIAQWFLPACRRLRYLASRTRGLIEPVIAARQKEKAICYSHGRQP
                     PVYDDAIEWTERAAKGRPYDAAMSPLLFSINALHTTTDLLTQVILDLSTQPDLIVALRQ
                     EILSVKPQQNGWKNASLNQLLLMDSAIKESQRLKPTESILMRRYAMDDLTLADGNKIPK
                     GTVLGIPIFGMRDPKIYVDPDMYDGYRFQKMRDKPGFENKCQLVSTSPWHLGFGHGIHA
                     CPGRFLAAVQVKIILCYIVAKYDFKLAGGAPPKV"
     mRNA            <21339..>22823
                     /locus_tag="AFUA_2G18020"
                     /note="transcript AFUA_2G18020A"
                     /old_locus_tag="Afu2g18020"
                     /product="O-acetyltransferase, putative"
     gene            <21339..>22823
                     /locus_tag="AFUA_2G18020"
                     /old_locus_tag="Afu2g18020"
     CDS             21339..22823
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G18020"
                     /note="encoded by transcript AFUA_2G18020A; similar to
                     GB:BAC65217.1: trichothecene 3-O-acetyltransferase
                     [Fusarium sp. IFO 7772]"
                     /old_locus_tag="Afu2g18020"
                     /product="O-acetyltransferase, putative"
                     /protein_id="EAL94101.1"
                     /sec_met_domain="Transferase (E-value: 5.4e-14, bitscore:
                     48.3, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MKKQVTFKPFRLSPVDHSLPKVYIFKSLYFRGVDDTGSLSRLQDG
                     IDRLISCLPFLSGEVVPCADIPDKVGVLQVQMPCPSLQEIPMLLVKSYPNHTWPAASTS
                     ERWRNTALLDQSYRPLPDFIPPSKPRPVLRFQANFLADGLMLCMGYNHSVFDGTGAGNI
                     LEMLADCCRANPNSILALPTNGDIESELRGLLSSPGVAVANASQEAYAINCAHTEVEPE
                     PSSAMLYCWPFLLSSEKIECLQEACNSLLPHIVRLYSGTQSSLINQDTNWPHILSSNDV
                     LTALLAVSIEKAREATGALGHMSRSLAMAVNLRERLKPMPRHYLGNLVTTVWVSHHRPA
                     VKDLETMVLPVPACNRHEIDRDDLLWITHVAFRIRLGLNAINEEHIRGLIHYLHSQDDW
                     EQIGIHFTDPIFISSWRHLKVYELDFGPTIGHAEHFEMDVGTTDGVCVVMPANTRAVGK
                     TKKAPWDIRIVLNPEVLQALIASAIFGWAMVKDAST"
     PFAM_domain     21720..22619
                     /aSDomain="Transferase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02458.18"
                     /description="Transferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18020_0093"
                     /evalue="6.50E-13"
                     /label="AFUA_2G18020"
                     /locus_tag="AFUA_2G18020"
                     /protein_end="427"
                     /protein_start="127"
                     /score="48.3"
                     /tool="antismash"
                     /translation="KPRPVLRFQANFLADGLMLCMGYNHSVFDGTGAGNILEMLADCCR
                     ANPNSILALPTNGDIESELRGLLSSPGVAVANASQEAYAINCAHTEVEPEPSSAMLYCW
                     PFLLSSEKIECLQEACNSLLPHIVRLYSGTQSSLINQDTNWPHILSSNDVLTALLAVSI
                     EKAREATGALGHMSRSLAMAVNLRERLKPMPRHYLGNLVTTVWVSHHRPAVKDLETMVL
                     PVPACNRHEIDRDDLLWITHVAFRIRLGLNAINEEHIRGLIHYLHSQDDWEQIGIHFTD
                     PIFISSWRHLKVYELDFGP"
     mRNA            complement(join(<23500..24816,24874..>25119))
                     /locus_tag="AFUA_2G18030"
                     /note="transcript AFUA_2G18030A"
                     /old_locus_tag="Afu2g18030"
                     /product="catalase Cat"
     gene            complement(<23500..>25119)
                     /locus_tag="AFUA_2G18030"
                     /old_locus_tag="Afu2g18030"
     CDS             complement(join(23500..24816,24874..25119))
                     /EC_number="1.11.1.6"
                     /codon_start=1
                     /locus_tag="AFUA_2G18030"
                     /note="encoded by transcript AFUA_2G18030A; identical to
                     catalase (GI:71002918) [Aspergillus fumigatus Af293] PMID:
                     15933009 similar to catalase P; catP (GI:23344117)
                     [Ajellomyces capsulatus] PMID: 11932457 similar to catalase
                     C; catC (GI:13378326) [Emericella nidulans] PMID: 11157957
                     similar to catalase A, breaks down hydrogen peroxide in the
                     peroxisomal matrix formed by acyl-CoA oxidase (Pox1p)
                     during fatty acid beta-oxidation; Cta1p (GI:6320462)
                     [Saccharomyces cerevisiae]; GO_component: GO:0005782 -
                     peroxisomal matrix; GO_function: GO:0004096 - catalase
                     activity; GO_process: GO:0006800 - oxygen and reactive
                     oxygen species metabolic process"
                     /old_locus_tag="Afu2g18030"
                     /product="catalase Cat"
                     /protein_id="EAL94102.1"
                     /transl_table=1
                     /translation="MLIERGLLSIMASKCSGTWSTYKTYTTANGCPFMKPEGPPADGRT
                     LALNDHHLVESLAHFNREKIPERAVHAKGAAAYGEFEVTADISDICNIDMLLGVGKKTP
                     CVTRFSTTGLERGSAEGMRDLKGMATKFYTKEGNWDWVCLNFPFFFIRDPLKFPSLMHA
                     QRRDPRTNLLNPNMYWDWVTSNHESLHMVLLQFSDFGTMFNWRSLSGYMGHAYKWVMPN
                     GSFKYVHIFLSSDRGPNFSQGEQAKDNSDLDPDHATRDLYEAIERGDYPTWTANVQVVD
                     PAEAPDLGFNILDVTKHWNLGTYPKDLPKIPSRPFGKLTLNRIPDNFFAEVEQLAFSPS
                     NMVPGVLPSEDPILQARMFAYPDAQRYRLGPNHHKIPVNQCPMTFNPTLRDGTGTFDAN
                     YGSLPGYVSESQGVNFARPQEHDPKFNAWLSQLSSRPWMQTNENDYKFPRDFYNALPEF
                     RSQEFQDKMVENIIASVAQTRREIREKVYHTFHLVDPELSARVKRGVEKMDASFKQVSL
                     SRL"
     PFAM_domain     complement(23548..23742)
                     /aSDomain="Catalase-rel"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF06628.15"
                     /description="Catalase-related immune-responsive"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18030_0095"
                     /evalue="1.70E-07"
                     /label="AFUA_2G18030"
                     /locus_tag="AFUA_2G18030"
                     /protein_end="505"
                     /protein_start="440"
                     /score="31.5"
                     /tool="antismash"
                     /translation="NENDYKFPRDFYNALPEFRSQEFQDKMVENIIASVAQTRREIREK
                     VYHTFHLVDPELSARVKRGV"
     PFAM_domain     complement(join(23830..24816,24874..25044))
                     /aSDomain="Catalase"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00199.22"
                     /db_xref="GO:0004096"
                     /db_xref="GO:0020037"
                     /description="Catalase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18030_0094"
                     /evalue="3.90E-153"
                     /gene_ontologies="GO:0004096: catalase activity"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_2G18030"
                     /locus_tag="AFUA_2G18030"
                     /protein_end="411"
                     /protein_start="25"
                     /score="510.2"
                     /tool="antismash"
                     /translation="TTANGCPFMKPEGPPADGRTLALNDHHLVESLAHFNREKIPERAV
                     HAKGAAAYGEFEVTADISDICNIDMLLGVGKKTPCVTRFSTTGLERGSAEGMRDLKGMA
                     TKFYTKEGNWDWVCLNFPFFFIRDPLKFPSLMHAQRRDPRTNLLNPNMYWDWVTSNHES
                     LHMVLLQFSDFGTMFNWRSLSGYMGHAYKWVMPNGSFKYVHIFLSSDRGPNFSQGEQAK
                     DNSDLDPDHATRDLYEAIERGDYPTWTANVQVVDPAEAPDLGFNILDVTKHWNLGTYPK
                     DLPKIPSRPFGKLTLNRIPDNFFAEVEQLAFSPSNMVPGVLPSEDPILQARMFAYPDAQ
                     RYRLGPNHHKIPVNQCPMTFNPTLRDGTGTFDANYGSLPGYVSESQ"
     mRNA            complement(join(<26192..26278,26377..26494,26556..>27706))
                     /locus_tag="AFUA_2G18040"
                     /note="transcript AFUA_2G18040A"
                     /old_locus_tag="Afu2g18040"
                     /product="dimethylallyl tryptophan synthase FgaPT2"
     gene            complement(<26192..>27706)
                     /locus_tag="AFUA_2G18040"
                     /old_locus_tag="Afu2g18040"
     CDS             complement(join(26192..26278,26377..26494,26556..27706))
                     /EC_number="2.5.1.34"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_2G18040"
                     /note="encoded by transcript AFUA_2G18040A; identical to
                     tryptophan dimethylallyltransferase dmaW (GI:59806087)
                     [Aspergillus fumigatus] PMID: 15870460 similar to
                     GB:AAS92554.1: SirD [Leptosphaeria maculans]; GO_function:
                     GO:0050364 - tryptophan dimethylallyltransferase activity;
                     GO_process: GO:0009821 - alkaloid biosynthetic process"
                     /old_locus_tag="Afu2g18040"
                     /product="dimethylallyl tryptophan synthase FgaPT2"
                     /protein_id="EAL94103.2"
                     /sec_met_domain="dmat (E-value: 9.6e-151, bitscore: 499.1,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MKAANASSAEAYRVLSRAFRFDNEDQKLWWHSTAPMFAKMLETAN
                     YTTPCQYQYLITYKECVIPSLGCYPTNSAPRWLSILTRYGTPFELSLNCSNSIVRYTFE
                     PINQHTGTDKDPFNTHAIWESLQHLLPLEKSIDLEWFRHFKHDLTLNSEESAFLAHNDR
                     LVGGTIRTQNKLALDLKDGRFALKTYIYPALKAVVTGKTIHELVFGSVRRLAVREPRIL
                     PPLNMLEEYIRSRGSKSTASPRLVSCDLTSPAKSRIKIYLLEQMVSLEAMEDLWTLGGR
                     RRDASTLEGLSLVRELWDLIQLSPGLKSYPAPYLPLGVIPDERLPLMANFTLHQNDPVP
                     EPQVYFTTFGMNDMAVADALTTFFERRGWSEMARTYETTLKSYYPHADHDKLNYLHAYI
                     SFSYRDRTPYLSVYLQSFETGDWAVKCQDAACQPTSLPPDLSKTGVYYSGLH"
     aSDomain        complement(join(26276..26278,26377..26494,26556..27676))
                     /aSDomain="TIGR03430"
                     /aSTool="tigrfam"
                     /description="trp_dimet_allyl: tryptophan
                     dimethylallyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_2G18040_0009"
                     /evalue="4.70E-237"
                     /identifier="TIGR03430"
                     /label="AFUA_2G18040"
                     /locus_tag="AFUA_2G18040"
                     /protein_end="424"
                     /protein_start="10"
                     /score="784.7"
                     /tool="antismash"
                     /translation="AYRVLSRAFRFDNEDQKLWWHSTAPMFAKMLETANYTTPCQYQYL
                     ITYKECVIPSLGCYPTNSAPRWLSILTRYGTPFELSLNCSNSIVRYTFEPINQHTGTDK
                     DPFNTHAIWESLQHLLPLEKSIDLEWFRHFKHDLTLNSEESAFLAHNDRLVGGTIRTQN
                     KLALDLKDGRFALKTYIYPALKAVVTGKTIHELVFGSVRRLAVREPRILPPLNMLEEYI
                     RSRGSKSTASPRLVSCDLTSPAKSRIKIYLLEQMVSLEAMEDLWTLGGRRRDASTLEGL
                     SLVRELWDLIQLSPGLKSYPAPYLPLGVIPDERLPLMANFTLHQNDPVPEPQVYFTTFG
                     MNDMAVADALTTFFERRGWSEMARTYETTLKSYYPHADHDKLNYLHAYISFSYRDRTPY
                     LSVYLQSFETGDWAV"
     aSDomain        complement(join(26401..26494,26556..27673))
                     /aSDomain="TIGR03429"
                     /aSTool="tigrfam"
                     /description="arom_pren_DMATS: aromatic prenyltransferase,
                     DMATS type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_2G18040_0010"
                     /evalue="2.70E-150"
                     /identifier="TIGR03429"
                     /label="AFUA_2G18040"
                     /locus_tag="AFUA_2G18040"
                     /protein_end="415"
                     /protein_start="11"
                     /score="499.1"
                     /tool="antismash"
                     /translation="YRVLSRAFRFDNEDQKLWWHSTAPMFAKMLETANYTTPCQYQYLI
                     TYKECVIPSLGCYPTNSAPRWLSILTRYGTPFELSLNCSNSIVRYTFEPINQHTGTDKD
                     PFNTHAIWESLQHLLPLEKSIDLEWFRHFKHDLTLNSEESAFLAHNDRLVGGTIRTQNK
                     LALDLKDGRFALKTYIYPALKAVVTGKTIHELVFGSVRRLAVREPRILPPLNMLEEYIR
                     SRGSKSTASPRLVSCDLTSPAKSRIKIYLLEQMVSLEAMEDLWTLGGRRRDASTLEGLS
                     LVRELWDLIQLSPGLKSYPAPYLPLGVIPDERLPLMANFTLHQNDPVPEPQVYFTTFGM
                     NDMAVADALTTFFERRGWSEMARTYETTLKSYYPHADHDKLNYLHAYISFSYRDRTPYL
                     SVYLQ"
     PFAM_domain     complement(26573..27634)
                     /aSDomain="Trp_DMAT"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF11991.11"
                     /db_xref="GO:0009820"
                     /db_xref="GO:0016765"
                     /description="Tryptophan dimethylallyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18040_0096"
                     /evalue="8.50E-115"
                     /gene_ontologies="GO:0009820: alkaloid metabolic process"
                     /gene_ontologies="GO:0016765: transferase activity,
                     transferring alkyl or aryl (other than methyl) groups"
                     /label="AFUA_2G18040"
                     /locus_tag="AFUA_2G18040"
                     /protein_end="378"
                     /protein_start="24"
                     /score="384.1"
                     /tool="antismash"
                     /translation="DQKLWWHSTAPMFAKMLETANYTTPCQYQYLITYKECVIPSLGCY
                     PTNSAPRWLSILTRYGTPFELSLNCSNSIVRYTFEPINQHTGTDKDPFNTHAIWESLQH
                     LLPLEKSIDLEWFRHFKHDLTLNSEESAFLAHNDRLVGGTIRTQNKLALDLKDGRFALK
                     TYIYPALKAVVTGKTIHELVFGSVRRLAVREPRILPPLNMLEEYIRSRGSKSTASPRLV
                     SCDLTSPAKSRIKIYLLEQMVSLEAMEDLWTLGGRRRDASTLEGLSLVRELWDLIQLSP
                     GLKSYPAPYLPLGVIPDERLPLMANFTLHQNDPVPEPQVYFTTFGMNDMAVADALTTFF
                     ERRGWSEMARTYET"
     mRNA            join(<28207..28280,28328..28504,28519..28624,28730..29239,
                     29309..>30328)
                     /locus_tag="AFUA_2G18050"
                     /note="transcript AFUA_2G18050A"
                     /old_locus_tag="Afu2g18050"
                     /product="FAD binding oxidoreductase CpoX1"
     gene            <28207..>30328
                     /locus_tag="AFUA_2G18050"
                     /old_locus_tag="Afu2g18050"
     CDS             join(28207..28280,28328..28504,28519..28624,28730..29239,
                     29309..30328)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_2G18050"
                     /note="encoded by transcript AFUA_2G18050A; identical to
                     oxidoreductase (GI:66853780) [Aspergillus fumigatus Af293]
                     PMID: 15933009 similar to oxidoreductase (GI:4499843)
                     [Claviceps purpurea] PMID: 10071219; GO_function:
                     GO:0050660 - FAD binding"
                     /old_locus_tag="Afu2g18050"
                     /product="FAD binding oxidoreductase CpoX1"
                     /protein_id="EAL94104.1"
                     /transl_table=1
                     /translation="MSHRILCVAFCVCSLVAVSSIYSPPFNHPIVYSNNAICFQLSTWR
                     IPQLYLAVLIRRFDLSLSTRGVMLAVTVGVGSSQHHSQRSGLSLTFAMTPSMITLLVKT
                     CVISQRTAVGEPHRPGWVWEVGRTEDETCHAHSPRGAPCHQGRIPLYSAAVESVDQIQV
                     AVRFAQRHRLRLVVRNTGHDTAGRSSGSDSFQIHCHRMKQIEYHDNFRALGSDIDRGPA
                     VSVGAGVTLGEMYARGARDGWVVVGGECPTVGAAGGFLQGGGVSSFHSFIDGLAVDNVL
                     EFEVVTAKGDVVVANDHQNPDIFWALRGGGGGTFGIVTRATMRVHLNSPVCVSEVAVSG
                     LRNNSLLWTKGITGLFSILRSFNQQGIPGQFILRPLSKDQVNASLTLYSLNTDDTRRSA
                     ENMLSIRNILESTTLPFTLASRCLPKISDALRKGPDMLPVNYGIITGSVLVSEDLFNSE
                     EGPLHLAKQLEHFPMGPMDLLFTSNLGGNVSANTGKKHRDTSMHPGWRQAAHLINFVRS
                     VSTPTAHEKARSLEELHSVQMRQLYDIEPDFRVSYRNLGDPLESDAAQVYWGPNYKRLL
                     EIKRKWDPEDLFFSQLGVGSEGWTEDQMCKRQQRLQQMLQYLMSSIAQRVYR"
     PFAM_domain     join(28823..29239,29309..29323)
                     /aSDomain="FAD_binding_4"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01565.26"
                     /db_xref="GO:0050660"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18050_0097"
                     /evalue="3.40E-20"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="AFUA_2G18050"
                     /locus_tag="AFUA_2G18050"
                     /protein_end="294"
                     /protein_start="150"
                     /score="72.3"
                     /tool="antismash"
                     /translation="YSAAVESVDQIQVAVRFAQRHRLRLVVRNTGHDTAGRSSGSDSFQ
                     IHCHRMKQIEYHDNFRALGSDIDRGPAVSVGAGVTLGEMYARGARDGWVVVGGECPTVG
                     AAGGFLQGGGVSSFHSFIDGLAVDNVLEFEVVTAKGDVVV"
     PFAM_domain     30092..30223
                     /aSDomain="BBE"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08031.15"
                     /db_xref="GO:0016491"
                     /db_xref="GO:0050660"
                     /description="Berberine and berberine like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18050_0098"
                     /evalue="2.10E-09"
                     /gene_ontologies="GO:0016491: oxidoreductase activity"
                     /gene_ontologies="GO:0050660: flavin adenine dinucleotide
                     binding"
                     /label="AFUA_2G18050"
                     /locus_tag="AFUA_2G18050"
                     /protein_end="594"
                     /protein_start="550"
                     /score="37.5"
                     /tool="antismash"
                     /translation="SYRNLGDPLESDAAQVYWGPNYKRLLEIKRKWDPEDLFFSQLGV"
     mRNA            join(<30585..30856,30929..>31676)
                     /locus_tag="AFUA_2G18060"
                     /note="transcript AFUA_2G18060A"
                     /old_locus_tag="Afu2g18060"
                     /product="conserved hypothetical protein"
     gene            <30585..>31676
                     /locus_tag="AFUA_2G18060"
                     /old_locus_tag="Afu2g18060"
     CDS             join(30585..30856,30929..31676)
                     /codon_start=1
                     /locus_tag="AFUA_2G18060"
                     /note="encoded by transcript AFUA_2G18060A"
                     /old_locus_tag="Afu2g18060"
                     /product="conserved hypothetical protein"
                     /protein_id="EAL94105.1"
                     /transl_table=1
                     /translation="MTISAPPIIDIRQAGLESSIPDQVVEGLTKEVKTLPALLFYSTKG
                     IQHWNRHSHAADFYPRHEELCILKAEASKMAASIAQDSLVIDMGSASMDKVILLLEALE
                     EQKKSITYYALDLSYSELASNFQAIPVDRFHYVRFAALHGTFDDGLHWLQNAPDIRNRP
                     RCILLFGLTIGNFSRDNAASFLRNIAQSALSTSPTQSSIIVSLDSCKLPTKILRAYTAD
                     GVVPFALASLSYANSLFHPKGDRKIFNEEDWYFHSEWNHALGRHEASLITQSKDIQLGA
                     PLETVIVRRDEKIRFGCSYKYDKAERDQLFHSAGLEDAAVWTAPDCDVAFYQLRLRLN"
     aSDomain        join(30606..30856,30929..31655)
                     /aSDomain="TIGR03439"
                     /aSTool="tigrfam"
                     /description="methyl_EasF: probable methyltransferase
                     domain, EasF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_AFUA_2G18060_0011"
                     /evalue="1.20E-120"
                     /identifier="TIGR03439"
                     /label="AFUA_2G18060"
                     /locus_tag="AFUA_2G18060"
                     /protein_end="333"
                     /protein_start="7"
                     /score="400.2"
                     /tool="antismash"
                     /translation="IIDIRQAGLESSIPDQVVEGLTKEVKTLPALLFYSTKGIQHWNRH
                     SHAADFYPRHEELCILKAEASKMAASIAQDSLVIDMGSASMDKVILLLEALEEQKKSIT
                     YYALDLSYSELASNFQAIPVDRFHYVRFAALHGTFDDGLHWLQNAPDIRNRPRCILLFG
                     LTIGNFSRDNAASFLRNIAQSALSTSPTQSSIIVSLDSCKLPTKILRAYTADGVVPFAL
                     ASLSYANSLFHPKGDRKIFNEEDWYFHSEWNHALGRHEASLITQSKDIQLGAPLETVIV
                     RRDEKIRFGCSYKYDKAERDQLFHSAGLEDAAVWTAPDCDVAFYQ"
     PFAM_domain     join(30645..30856,30929..31661)
                     /aSDomain="Methyltransf_33"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF10017.12"
                     /description="Histidine-specific methyltransferase,
                     SAM-dependent"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18060_0099"
                     /evalue="7.00E-81"
                     /label="AFUA_2G18060"
                     /locus_tag="AFUA_2G18060"
                     /protein_end="335"
                     /protein_start="20"
                     /score="271.9"
                     /tool="antismash"
                     /translation="PDQVVEGLTKEVKTLPALLFYSTKGIQHWNRHSHAADFYPRHEEL
                     CILKAEASKMAASIAQDSLVIDMGSASMDKVILLLEALEEQKKSITYYALDLSYSELAS
                     NFQAIPVDRFHYVRFAALHGTFDDGLHWLQNAPDIRNRPRCILLFGLTIGNFSRDNAAS
                     FLRNIAQSALSTSPTQSSIIVSLDSCKLPTKILRAYTADGVVPFALASLSYANSLFHPK
                     GDRKIFNEEDWYFHSEWNHALGRHEASLITQSKDIQLGAPLETVIVRRDEKIRFGCSYK
                     YDKAERDQLFHSAGLEDAAVWTAPDCDVAFYQLR"
     mRNA            complement(<32677..>33345)
                     /locus_tag="AFUA_2G18070"
                     /note="transcript AFUA_2G18070A"
                     /old_locus_tag="Afu2g18070"
                     /product="metalloproteinase, putative"
     gene            complement(<32677..>33345)
                     /locus_tag="AFUA_2G18070"
                     /old_locus_tag="Afu2g18070"
     CDS             complement(32677..33345)
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /locus_tag="AFUA_2G18070"
                     /note="encoded by transcript AFUA_2G18070A"
                     /old_locus_tag="Afu2g18070"
                     /product="metalloproteinase, putative"
                     /protein_id="EAL94106.1"
                     /transl_table=1
                     /translation="MHFFQALVALPLIAGAVASPLDTRATLENCNDEGVRAINNALTQA
                     AEMANSGASLIRSESDYSYSLFQSFFKTNDAQARNHVADVLDTIATEATNGNQGVVTYY
                     CTPEGIECTNSHSFTMTAYGDTDGTYGRVRTCPAYFTDFPAWSNICSVLDQATSSLHEL
                     AHTKGIYGPETYGYDAVHSLSSASALENAESYAFFSKCMVSYYFQVKYALLILFSSSFP
                     "
     PFAM_domain     complement(32734..33294)
                     /aSDomain="Peptidase_M35"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02102.18"
                     /db_xref="GO:0004222"
                     /db_xref="GO:0006508"
                     /description="Deuterolysin metalloprotease (M35) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_2G18070_0100"
                     /evalue="2.70E-31"
                     /gene_ontologies="GO:0004222: metalloendopeptidase
                     activity"
                     /gene_ontologies="GO:0006508: proteolysis"
                     /label="AFUA_2G18070"
                     /locus_tag="AFUA_2G18070"
                     /protein_end="204"
                     /protein_start="17"
                     /score="108.9"
                     /tool="antismash"
                     /translation="ASPLDTRATLENCNDEGVRAINNALTQAAEMANSGASLIRSESDY
                     SYSLFQSFFKTNDAQARNHVADVLDTIATEATNGNQGVVTYYCTPEGIECTNSHSFTMT
                     AYGDTDGTYGRVRTCPAYFTDFPAWSNICSVLDQATSSLHELAHTKGIYGPETYGYDAV
                     HSLSSASALENAESYAFFSKCMVS"
     mobile_element  37656..37931
                     /mobile_element_type="transposon:gypsy transposon family"
     mobile_element  38490..39629
                     /mobile_element_type="transposon:gypsy transposon family"
     repeat_region   39839..39910
                     /rpt_type=tandem
                     /rpt_unit_seq="actag"
                     /satellite="microsatellite"
     repeat_region   39850..39979
                     /rpt_type=tandem
                     /rpt_unit_seq="cagactaaccagactaac"
                     /satellite="microsatellite"
     repeat_region   39851..39975
                     /rpt_type=tandem
                     /rpt_unit_seq="agactaact"
                     /satellite="microsatellite"
     repeat_region   39911..39964
                     /rpt_type=tandem
                     /rpt_unit_seq="accag"
                     /satellite="microsatellite"
     repeat_region   39911..39979
                     /rpt_type=tandem
                     /rpt_unit_seq="cagac"
                     /satellite="microsatellite"
     mobile_element  40625..41251
                     /mobile_element_type="transposon:gypsy transposon family"
ORIGIN
        1 ctagataatc ttattacttt tctcccctgg cggtgcattt tatgagctgc tactaggcag
       61 ctatgttgat acatccgtag cttggtttcg tgtacgaccc cttgtactcg gatgtggatt
      121 gttaaacgtc acaaactacg acattgcgaa aatttgagag atatcagcac caaaacaagc
      181 agtggtgctg gaatgctatg ttagaggttc ctgttgtaat gacaggtaaa ttccacctaa
      241 tatcaaactg aaacagtgca ggggagttcc accatacttt catattgcca gatgtgaacc
      301 agatccaagc tcactaaact atgttaactg gggctctaca atatatgttt aacgctttgt
      361 ctcagagccg tgggccattt agtgtggatg gtgttcttag tattaagtgt acctggtggc
      421 agtgctgatg tctcagaaga ccgtgaaata atatctattt gcatgtgtca atctgttgta
      481 cttatatgat ctatattgaa cgcctaccat gcctcgaaag aggtgtcaac cctccagcga
      541 ttcggacgcg acttagccat gcctcttcct gtatttgctg tatcttttgc ctacctctat
      601 ctaacgggct cgttagtatt tgataccatc cattggctgc tccacaaatg gagcaaatca
      661 cagtggaaaa tccttcggtg gctttcatac tgtcaccaat ttcatcatct ttactacaac
      721 cgctcgctaa agttcaacga gcgatacgcg cgacataatt catggattgc attacctctc
      781 gaaatgcttt gcaaagtgtt tggaagcatg gcaggatggc tacttgcgcg acacttgatg
      841 gcagatgaca aacaaaacat cagtaccgca gctttactcg tggcgtgcgc attcgagatc
      901 atacgaacac ttgttgttat tgccattagt ggtcgagact cgaatcacat cgccttcgac
      961 accgtgccta aagaccataa ctggcttttt gttggtcccg agtaccacgc cttacaccac
     1021 gtttatcccg agcggtacat gggctcgatg gtcaaagtgt ttgactgggt agcgggaact
     1081 gcatactctc tacggaataa gagggtcgtc ctcacaggcg ggtcaggtgc gtttggctgc
     1141 gcaatagaga aacagctcct gtctgaaggg gtgaaggata ttaagaagct acacttcgga
     1201 aaggactgga cgcacaatga cgtctctgga gtcggcaaat ctctggaaga atctgatatc
     1261 cttatcttag cacatggtac caaagggagg gatgccatgg acgctaattg caagtcgacc
     1321 atgcgcctca tcgaactttt ccttcgacgc aaagctgctg aagatattca gcagaccaaa
     1381 actgtcccag agatatggta tgtaggcagc gagatcgaaa tccatcctgc atgggggaac
     1441 ccagaactgc aacgatactc cgcttcaaag cgtgccttcc taccttatgc tcgagcccta
     1501 tatgaccacc ctcggataat ttaccgtcac attgtgcctg cagcctttga atcgcgtatg
     1561 ggcaaagcaa ttgtatcgcc agattgggct gcccgtgtgg cactatggtg gattcgtcgt
     1621 ggagctcatt atgttcccgt cacctacacc ggactcgctt ttctgaactt cttcaagttc
     1681 cttcttttgg ttcgcccatc cacaaggcca gattgggagc tgtagcacag agtatttcac
     1741 aattgaggtt acgcagtata gagattgttt aacactgttc atagtttctg gcgtatgtac
     1801 acaacaaaca gggtgggtct tataggggaa gtgactcaag tatttttcgg aaacgttctc
     1861 tttctccgat atatcctcca ttcaattgtt ccttgaggga tacatacgag tccagtggca
     1921 tcgataaaac tgaaattccc gccgcatatt tttcttgccc cgaaccacaa gctaaaaata
     1981 gcttcaacga gactgttgca tagaccggga cgttttggcg ggatttactc ccaagaagtc
     2041 tgggttaccc cggtggacgg tcaagatccc gactaccaac actttgacat gagccaggac
     2101 gtcttggcca aatttactgc ccaaaatggt aaagctaggc tgcgatgttt tagagcattc
     2161 agtatccaac atttgacacc tgaatactgc gaaagtatga gaggatattt tcttcactac
     2221 aattgtgttt tggcagataa tcagaaattg gtgcaaaaag tgccctatgc tcatcgccgt
     2281 tatgcgacgg aaatcttcta ggcgaggcaa gacaaatcca aagtgaaacc agtacgagtc
     2341 tacaggggtt atccagcata cttcacacat aatcccatca acctcagcaa ctttcctaaa
     2401 gccctgtcgc gctaagggag atgagcccaa cactcaaaac agatcagaat tatggcatcc
     2461 ctgttaatgt cacagataag tcaactgctc gtttcccacc attataatct gcactgtgct
     2521 aaaaaaaaaa gggaaggaaa agggcctgga tcccatgcct ccccttcagc acgtcaaagg
     2581 gccagtccca aggtggtgag ccggcccccc ggcttcattt acgtagcagt ttcttaatgc
     2641 cttcgctgca gcttttctga agtctagttc ccgagtccaa gattcgccgc ttccattgtc
     2701 ctgaccccac tagtctcagt cacaaccata gctactactg ctgctaatct atctaataag
     2761 aagaccctag tatttattac cattattcca gcctgcaggt gaatagacac atggcgccct
     2821 ccccgttgcc cgccattcac ctgccagtca gatactgttg ccagttgaca gcgaagtttg
     2881 tacgcggggt tgtcatcagg ccatcacatt ctgtaagaat tatcggagtc atgggccttc
     2941 tgagttggct gttgctggca aaagctctgg ggcaatggct cctcttcagc tgctctgccg
     3001 taactcttag tcatagtcac actgggggcc tttggatgga acgtgaggtt tattaacact
     3061 atggcttcca cttctaatga agatggacat atcaccattc ttgctggtct ttactctcag
     3121 gaagaggagt ttgttgttgt ctagagcatt cttgctcgta tcttatccct gcattgggcc
     3181 acatcaggag atattctaca gggtaagcag cctgatggcg ctttgtcttt ggtctataca
     3241 tactatcatg gtggaacagg tctgctggac tcttgtgtaa tctggaaatc agtgatgtgg
     3301 gctacttcct ccttgtacaa aaagctataa tgtgttaaca attgcgcatg gatgagggtg
     3361 taaaagccga aggggataca tgcttgtcta actctgagat aatgctgaag agggttttag
     3421 acatgatgct atatgcagta gagccgatcg cggggggtgc tcgaggtgga aggatgtagc
     3481 tagcttacgc cacgtataaa atgctatgtg ctcaaagcca tatcctatag gatgccttgt
     3541 caccagaggg cattagtgat atccggagaa tataaccatt cttttaggac tgacttcctg
     3601 taggcaaact atactctcta ctttagcccg acctgcttga acttaactaa gcctgacagg
     3661 gcaacactct acctttgcag tgtgactaca atagcctcat gaagtcattc gaccggtatc
     3721 atgcaagctc tggaatctcg tcgtaaacac cgttaagagg ggcgtttgtt ggaatatatt
     3781 ccgatctgct cgcaactgcc agtgctgcgc tctcatgttc gtcgtatgtg tgcctcacac
     3841 agtcatgtcg cagtaaccag gctgggcgtg gatcataggt tggtttccca tgagcttggt
     3901 cagtatccca gtttgcatcg aactgcctct ccatcgcctt gatcgaagct gcctcgacca
     3961 ccgaaactcg cttctggctg gatcatctat cggcagaatt ttacagccaa ggtggccagg
     4021 agtacacacc gtaatttctc cacaacccgc agaccgacag gcatgttttt ctttccacag
     4081 agctccaggc aagtagcgac gactgctgca tcttcaatgg ccatgttggc tccttgaccg
     4141 agattggggt gcatagcatg ggccgcatcg ccaataacta tcattctacc accctttgag
     4201 acccagggag acaacggatg ccgtgctagt atagaatgat tctagcagcg ctgtggcggt
     4261 gtctttgaca ggatggcagc aagcttttga cccactggcc agtccttgac caattccacg
     4321 acatgctgag ggtctgcagg ctggagccag gaattatcaa gtccttggac ttgcttgagg
     4381 ggtattagaa acacttccaa gaggaaaagc aagggaactg ctcactttgt gtggcatatc
     4441 ccaagacaca tttttaccct ttccgacggt acccaccaaa agagtagtat cctttccgag
     4501 gtacatgtta gcgtggtctg cccgacctgt gctgtcaagg atccaatttg cctctgggtc
     4561 atccctaatc tcgcgtgaat caaaatgtga tcgatatatg gcagcaccag tcgagtaggg
     4621 ggccacatct tttccggtga tggtacctgt agctttgcta tgtaccccat ccatcagcag
     4681 caatcacgca gtcagcagct accttgtgtc cattctccaa cacgattccc gcgtttccct
     4741 cggactccca gtaatcacag acgatggctc cgaatcgaag atcaatgccg caatctttag
     4801 ccttcccata cagcaggtca ataagtcccg acatctgcac cacttcaacg ttgagaaggt
     4861 cacctggagc atatggaagg cagtctctga gctcaccgtt actatcgtag tagtcgaagg
     4921 agctgatggc ggcgcgtata gagtcaatag ctggtctcat cgacttgtcc caccggcaca
     4981 gcacattcat gccattcgta cccaagccta ccaggtcacc tgtacattgt tagccatcag
     5041 cctaggatgt gggaacttcg cccagggcga acctacctag ccagtgatgg tcttcttttt
     5101 ttcaaaccca atcacagagt gcccccttcg gtggcactca actgctgctg taagtccagc
     5161 tatgccgagt cccacaataa tcacagtaac tccagtggaa ttggggagcg taaccgtttc
     5221 tgtagtgaga aggcttcgtg ccatattgtc ctgaacaatg tgacctcgat tagctcggtt
     5281 gggagtaagg atacctcaat ctgcgccgtc gttcctattt gtcgttggcg tattagcttg
     5341 gcttcatttt atgtccgttg tcgacctatg ctggatgaag atcatatgcg aacccgtcaa
     5401 caccagcttg accagagacc aaggttgggg gaagttatct gcaagggtat gacttcaggc
     5461 ccatggccac gagtacatgg ccgacctaga ttacccacac cacctaatga gaacttgcaa
     5521 ggcgtcttca aacagcgtat tgacaaggca aggagtctat agacttcaat ggtatgtgaa
     5581 catgctggga ctcaccgcaa tcttcgggta tgtcttcgct gcttttatgg ccatgcactg
     5641 agaagtagag gtcctcaccg tattatgcgc tcaagagatg gttcagatct aattaaaaat
     5701 ccgaccttga gtgtacagca agcattgtgg tacagtgttg ctgaccgctg ttcctgaaac
     5761 cgaacaggcc ttcgataaac ccccaatgtt tactagaagt aataagtatg cagagctgag
     5821 gggtacatgc ttatctgact caaagtcagt atcaaagagg cttttcgaca taacacagct
     5881 gtagatccta tcggatgatg tttaaggcag gagtatatag ctggctcaca cctgggcatt
     5941 aagctacctg ctttacacga ttgattactc gatctttcta tcatccacaa acaaatcaca
     6001 ttgctctcca cttcttctat tgtaatcagg acaacttctt gtgagtcctg ccaggctcag
     6061 acgctgcctg ctggagggtg ggttctctta atcttacctg cgggcaagag ctgcatccgc
     6121 gccgcatgaa ggtacaagcc tggcaccata attggtggaa gcagagccga aagtgcctcg
     6181 tacacccgca aggcattttg agtaaaggat ggcgtagcca aggggaaatg ggagtcaggg
     6241 ttttttgggt tgtgtccagg ggtagagtca ttgcccatgt ccgtctcata cactgtagca
     6301 atcagcaatg gatgggaata atctccatta ggctcaatca ctgtgacgac aattctgctg
     6361 cccggaacaa gccttggcgt aggttcctct cgacctcagt ccacctgttg gaggttgtac
     6421 gagagctatc cctgcacagc tacaaacaag gctttggcca cggacaaggc gaccagcgcc
     6481 tacattatag cgcaggaacc tctagtcaga ctaattgttc aaccatcaga accttccccc
     6541 tgccagtgga actacacgct cacttatggg ctgatcgccc agcagtccca aacagtacca
     6601 gtctctttta cctgccatga tgtgctggac ctgtgggtca ttagggctcg ctggcggagc
     6661 ccaagtggcg cgatgtcctc cgtgggcgcg agcagcctcg gctaaacaat tcaccatcta
     6721 aatggtaatt ccgtcttccc tgttgtggga tacattgtga tggctatcga ggtgatgtgg
     6781 cagcttaatg agcttacatt gatgaaattg agaggtatgt gctgcacgat gtttctatca
     6841 gggcgccact ggtgaccgta gatgatgaaa actaaattga agtccagttc agcaagcgtc
     6901 cattcgtgac tgggggcctc gttggtggat ggcatagata aaaccatatg cagggcagca
     6961 ttggtgtcaa cacgtggccc gggggactaa aacatgcgtt gtatctgggt ttagcagcag
     7021 gaaagtggga aagtcggaaa tcaggctgta cataaggtct atcttcacta cagccctacc
     7081 tttcatgaca tgaacaatgt gactatcacg cgccctgcac gaccaacatt gagaggatca
     7141 tcaatgagaa ccttggtgag ttgccctatg tgctgcactt tatacgtttt aagaccttat
     7201 taaattttat ctgagtgtca acttacggcc ttgacaaact gtcctaagac cttactgaaa
     7261 ctacatgccc cctttcaaca taatgccatt cttcctctgc ttaactcacc agctaccatg
     7321 tttcatagtt gcgaatcttg attgaattct gagatgctat agatgtgccg actatgaata
     7381 cccaagcctt tcgcctagcc atggagatat gaaccattga accaatctca tgtcattgga
     7441 actgcatcgt catatagggc tcctgtaagt caactcagcc cacaaacttt ccagccgtgg
     7501 tgtacccgaa attcttctga gtctcaactg gatacgagag caacgtctcg tgtggtatgg
     7561 tcaagtattg attctcttct tgttgaggcc accccgttag cgtcgtgctt gggtagtaaa
     7621 tggggaaacg cgtacctggc gtaggtaact gtggactctg gcggtagcca tgatcaatcc
     7681 gtcctcgttt gtgtggctca cagatgcact gtgaatacag gaaccaagta tgatgaaagc
     7741 atctcacggt gccaattcgg catattgtac accgtctttc accgccggca gtggctggga
     7801 agtggcctgt aggtcggttc cggggatgaa gcgcgtggca ccattctgtt tggtggttcg
     7861 tgtacatgcc accatgcaaa ggagcatacg ctcctgccca atttcatact tgtcgactgt
     7921 ggtcgcagga acgatactga aatactatgc gtcatcccgg tggaggggct ggtcaatgtc
     7981 cccggggcca acacataggg ccgtgttggc tgttatctaa gagtgtgatt cgagctcgac
     8041 cttctcttga cccatccaca ttgtgctccg tgtgtagagc agagcatcga atttgcaacc
     8101 cataaagggt gcattgcaac atgctccatg aatgttcttg ggtgtgcggc tagtccggtt
     8161 gcgtatcgtg ttttattaca acaggtctct aagcttgctt ggtcaatgaa cggcctaaca
     8221 tcatcctcaa ttaccttcgt tgtcctcgcc tcgacgaaac catggaggat aactgcccct
     8281 tttcggatca ggcactgaac agccttctct ggagacgttg aacccactag gtagtatgtc
     8341 aaatgacgga ttctggggaa ccccaatgtg atattgagct tgtaccaagt ctgaccaagc
     8401 cattggcgca acgcgcctga ttcctggatc ccacctctgg aactacagcg tccccttctc
     8461 tgaggacgat gtagtatggg ccgaccaaca gcccggggat accttaatta tattgggcag
     8521 tgtgttccat gtgggaagct ggaacactac tgatcgagtg cgtcttgtat tgagcacgtc
     8581 cgccgtccgg ggcaagtttc gtggcgagga aaatggatat ctcacgtact ccaaggatca
     8641 tatttccagg ttgccagtta atctccaaaa attcttcggt taaaccttct tttcgccctc
     8701 ccttaactat gtcgacttca agggcttcct ccacccgatc aacccagatc ctccggctaa
     8761 ggggtttgac cattcgatag gtgaagttaa ccggtggtga agaatccgac tgacagacct
     8821 ggactttagt ctgtctatat tgcttggtat attatcgaaa actgattaat gggctttgct
     8881 tctcatctcg ctccgatcaa tcccatgttg cttttagctt tttttctttt gcatttacat
     8941 cattacttgg gccttcaaat ttactgtttg gcctaatggc tacttattcc cgaaactact
     9001 gtgcgacttg ttggtatagg tggcagagga cgatgacatc catgtagccc tggcatggct
     9061 gattccactt tgaggttacc agttgggatt cgtcgtcgct cgaatgtcct cgaccaacgt
     9121 ctagccatag caaatatact gtgcaccatg tcaagaagta gcctcattgt cacggtatga
     9181 cttgattacg aaaaaattgc attgacgcct actacagcac caggaagata caatttcagt
     9241 ttaccttaca aatgcctaac acacatggag acataaatct attactggat agaactgtcc
     9301 tttgacattt cctaatttaa atgccagtgt gagagtgctc ccagcaccgg cacaccgacc
     9361 aggctgttgc ctcggccttt ttgacattca agcaggccaa tgttgcagca atgtagacaa
     9421 tttgcctgcg tctctgtgaa gattaatcct cccttctgct cattatatta actatgacca
     9481 taaaaccttt tcactgtgca catatttaat atccattctc gttgttagac ggggaaatta
     9541 tgcaatgcca tatattcagc gctgaaaggg taatcaaggt agccttctct tgatagcgtg
     9601 ctatagaaag aggcacgatc gtacttttga agctggatgc cagccatgac ccgaaagggc
     9661 aggtctggag tcgagataaa gtacctccca aaagcaatgg ccacattggt gtaagtcgct
     9721 gccgccatct gctccgtcac cttctctgcc gatgccgcat catacccgcc tgccagcagg
     9781 ataggtgagg attgacccca gacacgcaca aacacctcat gattagggtc aggatggggc
     9841 ttttcctcat caagccatcg ggagttggca agatggagat atgcgacatc caatcgccgc
     9901 atctgggcaa tgagatactc aaactgtggc acaagctcgt ccattgttcc catccccaga
     9961 tactgactgt agggggagag tttgacgccg acacgatcgg cacccacggc ctcgataacc
    10021 gcccgtgtta cctcgaccgc aaaacgagct cgattctcga tgcttccgcc ccatcgatcc
    10081 tggcggtggt tgcaagactt ctgtgtgaac tggtcgatga ggtacccatt ggcaccatgg
    10141 atctccaccc catcgaaccc agcattgatg gcgtttcggg ccgcctgcgc aaaatctgcg
    10201 atgcactgct ggatttcgtc ctcagtcaga gctcggggaa gaggtccctt ctcttctaca
    10261 ggcacggcgc tactagagat caggtccttc atgtcggcga gtacgtccgg atctgcggcg
    10321 cggccggtcg cccataactg gcagaaaata aagcattttt tcgaatggac tctagaaaca
    10381 atctctctcc acgcctcgcg ctgcggctca ctccatatcc ccgggacatg tttgtaaccc
    10441 atcgccttgg gggtgatgtc tgttgcttcg gtgatgagga gggtgccagg aaccgatgca
    10501 cgctgaccgt aatactcttg tacaaaagga agcgggaccc cctgtccatc ggcccggaat
    10561 cgagttgtcg gcgccatgat catcctatgt tggagatgac atcttcccac cttgagcggc
    10621 ttgaatagct gagcagagga cggttcttct cgcattgctt ctaatccacc aagtacttgg
    10681 aacacggtga atgtcgaagc tcagtctgac cagtggaggt atcgacgcga acttttcagg
    10741 tcatggaagt gtggagtatg gtctacaggc ttggaggact ttgtattgat tctggcatcg
    10801 ataactgagc agacaagacg ccattcgggc acaatttctt tctgctggac aattctcata
    10861 cagccatgtc gtcccccttg ccgagccaac gccactattt gtttatgtgt ctattattcg
    10921 atattcacgg ggaaaggtga gctgacttgt acgtactctg tctactccaa tgccctcacc
    10981 tttcttcagc tgcagagccg tggagcggaa ctccttgctt ccccgtttac atacttggga
    11041 attgaaatca ggacccatat ctccatgacg agtcttttat catgcacatg ggaaatggcg
    11101 gtcagttaaa acatgatcaa tactactgtt acgcctttac tccaatgcac cgatagctaa
    11161 taagaagagc tcctccaccc tcccacaaag aggcaaggga gagccagaag agactgaggg
    11221 tggtgggcga aaacagctcc aagcgtatat gtgctactgt gcccaagact tcaccgtact
    11281 ttctcaatgt gtgaataatg aggactagac gagacactct taataagaga tcatctacca
    11341 gaaagggcgt acgttactac caaactctgt gtgattaaat gtacacacat tctttcaaca
    11401 aacaaatttg atccatcttc tatagagtag gcactccgca ccatgactat cctcgtgctg
    11461 ggtggccgcg gcaaaacagc tagtcgtcta tccttgttgc tggacaacgc cggagtccct
    11521 ttcctggtcg ggtccagttc aacttcgtac gtaggtccct acaagatgac gcactttgac
    11581 tggctcaacg aagatacctg gaccaatgtg ttcctgcgcg catctctaga cggcattgac
    11641 ccaatttccg ccgtctacct agtgggaggt cacgcaccag aattagttga tccagggatt
    11701 cgatttatca atgtagctcg agctcagggt gtcaaccgct tcgtcctcct cagtgccagt
    11761 aatatagcca agggaacaca ctccatgggc attctacacg ctcacctcga ttctcttgag
    11821 gatgttcaat atgtggtctt gaggccgacc tggttcatgg gtaagtttcc gaaaaccaca
    11881 tcctgccgga ggtttgctga gccccctcct agagaacctc ctggaggatc cacatgtcag
    11941 ctggatcaag aaggaggata agatctactc cgctaccggg gatggcaaga tcccatttat
    12001 ctctgcggac gatattgcgc gagttgcgtt ctctgtactc acagaatgga agtcacaaag
    12061 agctcaggag tattttgtcc taggtccaga gttactttct tatgaccagg tatgttagac
    12121 cgtcttctac gcgcggcagg atggtgttgt gctgacggcc ttctacaggt agcggatata
    12181 ctcacaactg ttctgggccg aaagatcacc catgtcagtc tcgctgaggc agacttggct
    12241 cggcttctaa gagatgacgt cggcctacca cccgatttcg cggccatgct tgcttcaatg
    12301 gagacagatg ttaagcacgg tacagaggta cgcaatagcc atgatgtgaa gaaggtaact
    12361 ggaagtttgc catgcagctt cttggacttt gcagagcagg aaaaagcgcg ctggatgcgg
    12421 cattaaaggt attttgggag gaaggaagtc catgatgacg tttgatcctc tgtgtcacca
    12481 gcgctttgat atcctccata aagagttagc atacgactca agacgtatgc taactatcta
    12541 gaaatagcca aacaagataa ttcttaggct gatgtcatta gcttatcggc tgttactcat
    12601 tttccccgtt gcagtaacca agttttctca ggttcccact gcgatgagtt tgactacagc
    12661 aggttctact tctttttaag ttgacgcctt caacataaca acttccaaat aactcgacaa
    12721 tatattctct attcagaaga acattcctga gggcacttat cagactttgc tgtaaatggt
    12781 aagctggtaa atcctcagga ctgcaaatat agacaatgga agccccgata tctttcagcc
    12841 cttctctggg aatcctaaac attgttttta acactgattc tctctttgaa agtcatatag
    12901 tgctcatgat ccgcatatcc agtaaccgat ccagagagga ctcccagctc ctcatcgaca
    12961 ttcacggcag aaatctatcc actgtcagca tgaacaagtc tccaaggcgg aaaaatagat
    13021 gcacaaatgg gattctcata tatcaaatcg aatgagtaac ctggctatga gcttcgtgac
    13081 catcattcta gtgaggttct tcccgatgca accatgcttt ccatgtccga atcaaaggct
    13141 cgcccgttcc atggaaagca gtgtatcatt cgatgcctca atccatcttt ctggtcggaa
    13201 cagcgccgca tcacgtccgt agatgggttc attgcggtgt gctgtataac caaagcatcc
    13261 gagattggtc ccagaaggaa gacgctcacc acacaagtcc agcccctcgg ggccgacaac
    13321 acggtacaga gacatgcgtg cagtgctgtg taatcttagg gtttccttga ataccgcctg
    13381 aagatattta agggtggaca cctctaccca tttgggtgga tagctgagat tgccagagcg
    13441 gacggccgag tccagctctt cctgtaaacg tgcaagggcg gctggatgtt tgatgagata
    13501 gtacatgaag aaagttaggc ttgtaccagt cgtgtcagtg ccagcgaaga tagttgatat
    13561 ggttgctccc agaactcctc tctcctcgag agtctccggg ttcttttgag aggcatccat
    13621 aaagtgagca agtaaatccc ggtgtgaggc ttttcgttgt gacggcgcga ctgcagttcc
    13681 tgtgcagctt ttgggaaaat ggaatctaag cgtggtccta tgaatccagc cacataattg
    13741 accagccagc ccactatagg agtcgtggaa atatagcaag caaacatgaa tttgctttgc
    13801 aatatggaca gtattccatc ggtatccttt ccttcactca agtatcctag cttgttggag
    13861 aaggcgatcc agtgtagact ctccaaggag aatagtcgca tccacagcac cacatctata
    13921 gtgactctac gacagatttg atcctctaat tcttgttgaa tctggtccat cgctgattcc
    13981 atccccagca aacttggaat ggcaaagtat ggtgccatcg gacgcttcaa tcaggtgtga
    14041 atttcttcgt cctagtcgaa ccgaccgagt gtatttctct gcctctttcg aaggttgcaa
    14101 cgcaaatgta aaaattaccc ttcttagatt agctgctggc tgccataaga tatgactacg
    14161 ctgagtgagg ttgacaaggg aatgctgccc tctacctttt tcagaatcgg gttggtacga
    14221 tatatgactg gaacacctga cggatttccc agattgacag aattagggcc agtgcgtact
    14281 aggtctcctt agcgtttatg aagggtcaga agcacatcgc cgtagtcgcc cttgatatag
    14341 tggtgctcgc gccatagatc ggttatcttt gcccagaaag gtccagggat atgtctcaaa
    14401 cggaaccagc tccgaatgat gtgagcaagt aaaagcgtca ccactggtaa cgtgaatgtg
    14461 agaaggagca ttttggtaga agctggttct gaagcgaatc cctacatcag gttatatggt
    14521 atgtgtagcc tcaaattgaa cagcaggggt actgaaccat cgtcagctgg gggacgcata
    14581 tacttttgaa atcgtacact ggcaggaagg tcaaggaagt cagatgtatg ttcagagcgt
    14641 acgcaaggga cctgctgtgt aacaggctct ccggaccttc taaaaatgct ctgttgccaa
    14701 tattcaagcc taaaaaggga ttttgcacca ataccttggt ctcgtccggt tttcacgtca
    14761 atgagacagt gaagcaactc ctctagagaa aagataagtg catgcaccgt tgttacctga
    14821 atattacgta gtagactgtc tgagtgtact atgcgactcc ttcccctatc agccagggta
    14881 ggcgtagtta ttctgggttg ggctagatca ggtaatacaa tgtaattcac agcccaagca
    14941 accatttcaa agataatgct gttttcattc ctgaaatact aatattcctc tgcatatcta
    15001 tcaaaagacg ggtcgtggcc cgctggggtt gccatatgtt gtgatataag gacctttgat
    15061 gctgtggaat gtaacggaga tatagctgaa ggcaagatag ctctttgttg tctggcccaa
    15121 agacctaaca acagtcagtt tggacaatac agttgctcct tctctgaaat aagcttacca
    15181 ggcttcgtcc atcaaagctc gatgagtctg gacaaggtca tcccaaccga ggtagtcgag
    15241 aatctcgaca actgtatcgg agacatagtg atcttcagct gctgcaacac tgaagtatag
    15301 cttagggaca ggaaaaggaa catcagttct cagctcccat acccattgca tccagtactt
    15361 catctcgcag gtcgatggct cttcatccat caggcgtctc cacagccttg ccacaagatc
    15421 aaaccctttc tcgatgtctt cgccctggag ccgccctccc agcgtccaga catcacgggc
    15481 atgctctatt gacttcatac gaattccagt atatattttg atcctggctt tacatgcatc
    15541 gaccgcgtca taggaaatac catcccaata ctccataaaa cggccattcg ttggaaccat
    15601 ccagtcttct agcgtactca gagcggagat aaagttggca ttcttgagat tcagctttcg
    15661 gatagattcg aacatgatct gtgtgttctc aaccccagtg atggcggagc gaatcgcagg
    15721 catgaagtag gacttcaaca tgaatgctcc ttcactcaga tcgagcccat ggagtctctg
    15781 attcttgaat gggactttgg agataatttc gtcattgttt agagccacct cttccggcac
    15841 cagaacctcc cgctgaaaat gattaaacca agtgaagttc aggtttggct ggagggcctt
    15901 aagatcctcg atcatcttct tctcagcggt taggttgaaa gggtccttat cggtaccggc
    15961 cgcgggtgta atggtttcag cagcgatgcg aactgtgcat ttcgctcctt gttggtagtt
    16021 catgctaatc tccaggttct cgcctccagg gcagataccg cagacccagt gaacattatc
    16081 tcgcttgtcg ttgggccaag gtcccaaatt gggcgcgtag acggagtaga acatcaacag
    16141 atgctggtac tgagatccca cactgtactt tgcaagccta aggtatgtgg caagctttga
    16201 agctgcccgt tcccaccaaa gcctgtggtc ctcatgctga aaaacaaggg tccgactcaa
    16261 tacctcaaat ggagctctcc attgatcttg aacctcttcg tctgttgttg ctgcatgggt
    16321 tgccgtctct tgtggatggc gcccttgcgc gtcggtcttg gtcatcgtgt tgcagttgtt
    16381 gtgtggtgga ggcaagtctc tgcttgtttc ccagaattat tgctcccttg agctggacca
    16441 aggaataggt atgtacgtat ctacgcagca gtagtatgat cgtctggcca ctctgccttt
    16501 aatatcaatc atttttgccg gttccgcgta cgagatggcg tgtgagttgt acgtaggaat
    16561 agaaacttgc ggagcttttc ctccctacaa gggagcagta cagaggaagc aagggaaacc
    16621 acccttgcct tgtggaatcc ggatgacgtc ttgcgcattt tctggtgcct tactgcaatg
    16681 aaacggctca ccgacgcctt tacgcactat atcagctgtt ccgtttgaga agcatgtgga
    16741 gccaggttta agcaatcagc aacataatac agtcagtctc tggcgtagca aaaaggtttg
    16801 ttgaattgat ggatgaccag ttgctttgca gcagcatacc tgtgtgaccg gacatttccg
    16861 taaaggggga acgctgctgt gagccgaaag tcgacgattt gctagtcaaa gcaaggagga
    16921 attacaaagg aatgatgaga aacgaggaca ccatctggag acagaaagtt ccgaccatga
    16981 acggcataaa gtctctcatg aggacagggc tttctttgaa aaatgcctag aggtcgataa
    17041 ccaattattc ctccagcaca ccagcacaca ccacttagag catcttctct aataatggca
    17101 tcagtcgaat cccgaataat cgcaatcact ggcggcgcct ccggcattgg tgcggcgacc
    17161 tgccgcctgc tcgctgaacg tggcgctgcg gttctgtgcg tctgcgatat ctcgcccaag
    17221 aattttgatg atctcaagat ttcaatcaag aaaattaatc catcgacaaa agtccactgc
    17281 gctacagtcg atgtaacctc ctctgtggaa gttcggcaat ggatcgaggg catcatatct
    17341 gatttcggag acctccatgg agccgtcaat gcagccggta tagctcaagg tgctggcatg
    17401 cgaaataccc ccacgattgc agaggaggtg gacgaagagt ggacaaggat tatgaacact
    17461 aacctgaatg gcgtgttcta ttgcacgcgc gaggaggtgc gtgccatgaa gggtctgcct
    17521 gctacagata gaagtattgt caacgttggc agtattgcga gcgtttctca catgccagac
    17581 gtgtatgcgt acggcacctc aaaaggagcc tgcgcctatt tcactacttg tgtagctgcg
    17641 gatgcgtttc ccttgggtat ccggatcaat aatgtctctc caggtgggtc atctccttcc
    17701 ccttcttcgg catggaaagc tgtcatattg atcacaatac tctcttgtag gagtcacaaa
    17761 cacgccaatg cttccccagt ttgctcctat ggcgaagaca tttgaagaaa tagaagagtc
    17821 atacaaaaag gaggggctat cgttgatcga ggccgaggat gtggctagaa ccattgtttg
    17881 gttactaagt gaggactctc ggccggtatt tggggcgaat atcaatgtcg gtgcttgcat
    17941 gccgtagatg aagtgggcat ttctccagtc tataccgtgt tgcgaacatt tcagaaatca
    18001 acctctaggt tagaagtgct ttttgcaaga ccatccagtg ttattggtgg aattaaccat
    18061 aatgaaaaat agttgtcgag gccattcctc cactcttcag gagtacgcag ggaatttgac
    18121 gacaaaaagc tgtgttaata tgtacaaagc ccccataaaa gccttactgc gttgaggtat
    18181 tttctcttta gcacctcgtg gaccttgccg ttactgatgt gcagattcaa cgtaaccttc
    18241 gaaatcccgg aattcctcaa acattccccg tgtcagatgt ttgcaatttg tgagatgcca
    18301 tcttttaact gagtcaatat aactccgttc ctttagtcaa ctatgctagt tttgtaaata
    18361 tcatcctctc tacagaattc ttcgcgcaat tattgccgaa cgaagctatc gggtcgacgg
    18421 gtaaagtctc acaagcttac tgccccttgc actctgatgt ctcatcagca gtaggggaga
    18481 aatgtgtgaa agtcttacaa atatggcaga atccctacaa cgcaactcat gtctgaagac
    18541 agaaacagtc cacctagttg caacgcctgc tatggacagt agctaacaac tgaatcatca
    18601 tggacttctt acaacggatc ttgggaattt tgagcagtga agatgttgca ccggcgttgt
    18661 ttgcctcaag catctcggtg ttgttcttga tactctcata tcaagttctc tacccacctt
    18721 caaaatactc tgctttcccc acgatcaatg gcacacgctg gctagcactc agcaatcggc
    18781 gaatattggc ggaatttgtg accgatgccc agggcctcat gcggaatggc ctagaggtga
    18841 gctggaattc tttgtactcg atcatctcca ataccaccga catccttgat cgctaaagca
    18901 ttcgatatag aaatacgata tcttccgtat tatatccagt attggcccaa tgactatcct
    18961 gcaccccaaa tatacggatg agattcacaa tgaccgacaa ctgaacttta tggcggtgct
    19021 agctaaggta catatcaaga agcccgttat gcggacaaga caggatcagc cgagttttaa
    19081 caataaactt aggagatgtt tcctaattac ccgggctttg atctcttccg cgaaggtaca
    19141 gatggaagca ctgtcttaca ggacgccgta aagtttggat cctcacggtg tttgggtagg
    19201 tcagccaggg tacatttgag catgtgagaa gtgaacctag tttgacacat ttaggtaaat
    19261 caacccaatt attgtcggat gaaacgagca ccctactgca aaaactctgg ggcgatgaac
    19321 cgggtgggta tcctcgttct ccgtactact accgtggtag ctaactgatg agatcagaat
    19381 ggcacgaggt gacggcaaaa tcctctgtcc atgatatcat tgcccaccta tcggccttgc
    19441 ttttctatgg gccagaactg tgcagccata aagaatggct ggaagttacg gatgagtatg
    19501 catccgtcgg gtttctagcg gctcgacagc tccgtctttg gcctcccata ttacggccca
    19561 tcgcccagtg gtttctccca gcttgtcggc gactgcggta tctagcaagc agaactcgtg
    19621 gcctcatcga gcctgtcatt gccgctcgac agaaagagaa ggctatatgt tattcgcatg
    19681 ggcgtcaacc gcctgtttac gatgacgcga tagaatggac ggagcgagct gccaaagggc
    19741 gcccctacga cgccgctatg agtcctctac ttttctcgat caatgcgctt cacacgacca
    19801 ctgacctgtt aactcaagtc attctcgatc tcagtacgca gccggacctg attgttgccc
    19861 tgcgtcaaga aattctctca gtcaaacctc aacagaatgg gtggaagaac gccagcctaa
    19921 accaacttct gctcatggat agtgctatca aggaaagcca acgactgaaa ccaaccgagt
    19981 caagtatgca tgtcgtgatc tataacctct cctttttcct tccgaatacc gtattgaggt
    20041 accacactaa ctgcggtcac tagtactcat gagaagatac gcaatggatg acttgaccct
    20101 tgctgatggc aacaaaatcc ctaaagggac tgtcctggga ataccaatct tcgggatgcg
    20161 agatccaaag atatacgttg acccggacat gtatgatgga tatcgatttc aaaagatgcg
    20221 tgacaagcct ggatttgaaa acaagtgcca gcttgtctct acgagcccat ggcatctcgg
    20281 atttggccat ggtattcatg catgccctgg tcgatttctt gcagccgttc aggtcaagat
    20341 catcctctgc tatattgtcg caaaatatga tttcaaactg gcaggtggcg cgcctcccaa
    20401 ggtacaatct gtcgggatag agttgatatc ggataccgag gcaaggctcg ccgtgagaag
    20461 aaggcaagag atggtgattg gattggagta agatctgaga tctgtttggt tcctattgtc
    20521 ggccattcag tataatctct tacgacagca caatatcgtc aaaaaaatag cagtggaaaa
    20581 ccaaggaagt aacgaagtca acatgatttt ttgattacac tattatacca tcttcgatat
    20641 tctaggctgt acaggcattg ctacgtagag cgttctgtaa tcccaatgtg tatatttggg
    20701 agtgtataca tgttcctcac cgagaacaac tcaattccac ggttattgtg aaattaaaaa
    20761 aaagaagggg gcgactatct ccttaccgtc cagtaagcct atttagattc ttcttgccaa
    20821 cttctagtca ttatgaagtg atgtaggtct agtgtcatct tgacatgggt gtattcaagt
    20881 accgccctcg aatggtacac actgggctca tgttggcgag catgcgtata gccgcaccgt
    20941 aagtgatgca attcattaac tatacatttc tatttccggc ttagtcgctt caacatggtt
    21001 ctgccattga gggatctatg taagggagat aggttatgga tgaccacgta cttgctgtga
    21061 aatgtctaca tcttttctgc gtctcgatgg cttgtcaact tgagcaagtg gcggtgagct
    21121 cagctcgatt ggagatatcc cttcaaagag ctgggaatgt tctttggcac tgtgagggag
    21181 acttgacttg tatctctatt tgcaacagca aaaggctggg ttgattatcg gcggcagtta
    21241 cccatacatt ctctcacaca aggcctgtta ttacagacgt tgcacccaat tctggtgcgc
    21301 aattgagaaa taatatattg caaattttcc ctctcaagat gaagaaacaa gtgactttta
    21361 aacccttccg tctgagccct gtggaccatt ccctgcccaa agtctacatc ttcaagtcgt
    21421 tatattttcg aggggtagat gatactggca gtctttcgcg cctgcaagat ggtatagacc
    21481 gtctaatatc ctgcttgccg tttctttccg gagaagtcgt gccatgtgcg gatatccctg
    21541 ataaagtcgg ggtcctccaa gtgcagatgc cttgcccctc cctccaagag atccccatgc
    21601 tcctagttaa gtcatatccg aaccacacat ggcccgcagc tagtacttca gagagatgga
    21661 ggaatacggc cttactcgat cagtcatatc gtccactccc tgatttcatt ccgccgtcga
    21721 aacctcgacc cgtgctccgc ttccaggcca atttcctggc ggatggactc atgctctgta
    21781 tgggttacaa tcactctgtg tttgacggta ctggagctgg taatatcctc gaaatgctgg
    21841 ctgactgttg ccgtgccaat ccaaatagca ttctcgctct acccaccaat ggcgacatcg
    21901 agtccgaact gcgcgggctg ttgtccagtc ctggtgttgc tgttgcaaat gcgtcccagg
    21961 aagcgtatgc catcaactgt gcacacacgg aggtagaacc cgaaccttcc tccgctatgc
    22021 tgtactgttg gcccttcctg ttgtcttccg agaagattga atgcctgcaa gaagcatgta
    22081 acagcctttt accacatatt gtacgcttgt acagtgggac ccaaagttct ttgatcaacc
    22141 aggacacaaa ctggccacat attctctcta gcaacgacgt gttgaccgcg ttgcttgccg
    22201 taagtattga gaaagccagg gaagcgacag gggccctggg acatatgagc agaagccttg
    22261 cgatggctgt gaatctccga gaacgattaa agccgatgcc gaggcattat cttggaaatt
    22321 tagtgaccac tgtatgggtg tctcatcatc gacctgcggt gaaggacctg gagacgatgg
    22381 ttttacctgt cccagcctgt aatcgtcatg aaattgacag agatgatctc ctttggatta
    22441 cccacgttgc gttccgtatc cgtcttggac tgaacgccat caacgaagag catattcgcg
    22501 ggctcattca ctatctgcac agtcaggatg attgggagca aataggcatt cattttactg
    22561 atcccatatt catcagcagc tggcggcatc tgaaagtata cgagctcgac ttcggtccaa
    22621 caattgggca tgctgagcac tttgaaatgg atgtcggaac cacggatggc gtatgcgtgg
    22681 ttatgccagc taacacaagg gctgtcggaa agaccaagaa ggctccatgg gacattcgca
    22741 ttgtcttgaa tccagaggtc ttgcaagctt tgatcgcttc cgcaatcttt ggttgggcta
    22801 tggtgaagga tgcttccacg taaccttttt aacagcagat ggagcaagtg acttaaaatg
    22861 atgaatgtgt ttacctagac tctacttatt tcatcctttc agattagcgt ggaataactt
    22921 ataagaagta gtgtaagagg ccgtgtactg cagcatgaat gttggcattt ctctgggtac
    22981 atcaaatctt gctggagtag ggaatggaag tgatctttat aagcattagt tacagtatta
    23041 tcaaacctgt tcagaatcca gcatattcac tataatctaa tctcattgct ggtccctttt
    23101 attgtctatg gcattgcaat gataattaac tcaagcttct acattaatta cttttacatg
    23161 aaatgtgcaa gtggtagtcg gtgaggtatt tcaccactta atatagtatt tagtaatacc
    23221 tatacctaat cgaagccgca cgcagtgcac ctatgcacaa ggggccatct tctatagtca
    23281 tgaagcatca catcctacat tctgcagaca aagggaatgc atgtatgtca agctttccta
    23341 gaatactagt ttactgtttg ctaggcctaa aacacagcaa ccagataaac aatctactgc
    23401 tggaaattaa cccacatgct gctactctac ggatgcgtaa taggagattg aaatagatag
    23461 gacactccgg cgactgccgt tgttttagtg atgagcactt cagagcctgg aaagagagac
    23521 ttgtttgaaa gacgcatcca tcttctccac ccctcgcttc acccgtgcag acagctccgg
    23581 atcaaccaga tggaaggtgt ggtagacctt ctcgcgaatc tccctgcgag tctgggccac
    23641 cgacgcaatg atattttcca ccattttatc ttgaaactcc tggctccgga actcaggcag
    23701 cgcgttgtaa aagtcccgcg gaaacttata gtcgttctcg ttggtctgca tccagggcct
    23761 ggatgagagc tgcgacagcc atgcgttgaa cttggggtcg tgctcctggg gacgtgcaaa
    23821 attcacgccc tgcgattcgg acacgtagcc aggcaaagat ccatagttgg cgtcaaaagt
    23881 gcccgtaccg tcacgaagag ttgggttgaa agtcattggg cattgattaa cgggaatttt
    23941 gtggtggttg gggccgagcc tgtagcgctg ggcgtctgga taggcaaaca tgcgcgcctg
    24001 gaggatggga tcttccgagg gcaggacgcc gggcaccata ttggaagggg agaaggccag
    24061 ttgttcgact tcggcgaaga agttatccgg gatgcgattc agcgtcaact ttccgaatgg
    24121 acgtgaaggg atctttggaa gatccttggg gtaggtgccc aggttccagt gcttggttac
    24181 atcaagaatg ttgaagccga gatcgggagc ttcggccgga tccaccacct gcacattggc
    24241 cgtccaggtg gggtagtctc ctcgttcaat ggcctcgtac aggtcccgtg tagcatggtc
    24301 agggtcgaga tcggagttgt ctttggcttg ttcgccctgg ctgaagttgg gtccgcggtc
    24361 cgaggacagg aatatgtgca catatttgaa ggagccattc ggcataaccc acttgtaggc
    24421 atgacccata tacccactca aggagcgcca gttgaacatg gtgccgaagt cactgaactg
    24481 cagcagaacc atgtgaagag actcgtggtt agatgtcacc cagtcccagt acatattggg
    24541 gttcaggagg ttggtccgag ggtcgcgtcg ttgtgcatgc attagactcg ggaatttgag
    24601 aggatcccgg atgaagaaga agggaaagtt gaggcacacc cagtcccaat tcccttcctt
    24661 ggtgtagaat ttggtggcca tccccttcaa gtctctcatt ccctcggcag aacctcgctc
    24721 cagcccggta gtcgagaagc gcgtcacaca cggcgtcttc tttcccacgc ctagcagcat
    24781 gtcaatgtta cagatatcgg aaatgtcggc agtcacctgg gtcaatcagc atgtcttcgg
    24841 gaacttaatg acgcctccgt aggagatcaa tacctcgaat tccccataag ctgcggcacc
    24901 tttggcgtgc actgctcgct cagggatctt ctcccggttg aaatgagcca acgattctac
    24961 caaatggtgg tcattgaggg cgagtgtgcg cccatcagcc ggagggcctt caggcttcat
    25021 gaacggacaa ccattggccg ttgtgtatgt cttataggtc gaccatgtac ctgaacattt
    25081 ggaagccatt attgacaata acccacgctc aattagcata agtcaaccgg ttgattgtcg
    25141 atacaatgtt cagtcctgac catttatgta tgactacttg gtaacaagtg gttctcattc
    25201 accgctaaaa ttcgaataca tgcgcctctc tggactgggt cttttcagcc cttgcatcac
    25261 aagctctcta tcattgacac ctgaccagcc ggatgcattt acttctcctt gcagcacaca
    25321 cgcctctcag agtatcgcca cgccaaagtg gcatgaccaa agacaagtaa tggctgacca
    25381 agttggcttc caccgtcttt tcagatccct agcgtttatc cttagcgctg aggcacatgc
    25441 aagcccttac atccagcaac gtcaagacga tgatactctg aacattccac caatattcct
    25501 gggcagcccc acctctgctg caatggctat caacccctgt atggcagtat ccgtggagga
    25561 gtccggttga acagaaacgc catggctgtt ggggagatgc gtagaaggtt taagtaatac
    25621 ctacgggctt ccaagctcgg aacctgatgt gttgtaatga cggattgttg cgagtcgcac
    25681 atctaggcgc tgactactga cagccgacat tcctatcctt gaattatttg acttccaaac
    25741 agattagcgt aaacaccacc tccctttagc gatgaaaccg atatgattat cttagtgttc
    25801 tggagtagac catcatcaag tattgaagtc tgtctttatg gctctgaggt gtttatggcc
    25861 tctgttagag agctacttga catattgtgt cggcaggtgc gcaagggacg gtgaaacaat
    25921 atgcatcttt attgcgcctc tagaccatta tttgcttcaa atataacgga tctcttatct
    25981 tgggcttttc agagcagaga aaacaacgaa agtctgacgg catcatgtct tgatcggagt
    26041 cctgcaatat tagtagcaaa gacagactag ggttcactcc ttgcgtctac aacttggcat
    26101 cacgacgata catgaaattt aagtgctaga gtctgggtac ctccgcgggt gtcatcgggt
    26161 tacagcccgg aagtaagtcc cgagctgttc atcagtggag accggaataa tatacccctg
    26221 tctttgacag atctggaggt aaagatgtgg gttgacaggc cgcatcctga cacttgacct
    26281 ttgattcgga taagtttgct ggtgtattgt caggatgaca tccataataa gggagccaat
    26341 gaacgtcttg tttgggaggt aaatcggctt accaactgcc cagtcccctg tctcgaagga
    26401 ttgaagatag acactcagat aaggggtacg gtccctgtag gagaaggata tgtaggcgtg
    26461 gaggtagtta agtttgtcat gatccgcatg ggggctgaaa ggcgcatcaa tccgttgctc
    26521 cacaaataca tcatcagaaa gaaaggtcta cttactagta cgacttcaaa gtagtttcgt
    26581 aggtgcgggc catttcactc caaccccggc gctcgaagaa cgtcgtcagg gcatccgcca
    26641 ccgccatgtc gttcatgccg aaggttgtga aatatacttg cggctctggg accgggtcat
    26701 tctggtgcag ggtgaaattg gccataagcg gcagcctctc gtctgggata accccgagag
    26761 gcagatacgg cgccggatag gacttcaatc ccggcgacag ttggatcaga tcccaaagct
    26821 cacgcaccag agagagcccc tctaaagtgg aagcgtctcg gcgccgtccg cccagagtcc
    26881 acaggtcctc catggcttct agtgaaacca tctgctccag caggtagatc ttgattctcg
    26941 acttggcagg actggtcaga tcacaggaca ctaggcgggg actggcagtg ctcttggaac
    27001 cgcgtgatcg gatgtattcc tccagcatgt tgagtggggg caagattcgg ggctccctca
    27061 ctgccagccg gcggactgag ccaaagacca actcatgaat tgtcttgccg gtgacgacag
    27121 ctttgagagc cgggtatatg tacgtcttaa gtgcaaagcg gccatccttc agatcgagcg
    27181 cgagcttgtt ctgcgtcctg atagtgccgc ccacgaggcg atcattatga gccagaaaag
    27241 cagattcttc actgttgagg gtgagatcgt gcttgaagtg gcggaaccac tccagatcaa
    27301 tgctcttctc cagtggaagc aggtgctgca ggctctccca gatggcgtgc gtattgaatg
    27361 ggtctttatc tgttccggta tgttgattga tcggctcgaa tgtgtatctc actattgaat
    27421 tagagcaatt taggctcaat tcgaacggag tgccgtatcg agtgaggatg ctcaaccagc
    27481 ggggggcgct gttggtcgga tagcatccga gactgggaat tacgcactcc ttataggtga
    27541 tgaggtattg atactgacaa ggtgtggtgt agttggcagt ttccagcatt tttgcaaaca
    27601 tcggggcagt gctgtgccac cacagcttct gatcttcatt atcgaatcta aaggcgcgac
    27661 taagaactcg ataggcctcc gcactggagg cattggctgc cttcatgaga gtcatcttgg
    27721 ataagggcat atgcgttggt actctttatg gtgttaagga cgggcagcac ctaatatacc
    27781 atgccatgat aatactgctg gttcacagtt gccggtccgg catgattctt tgtgcattgg
    27841 tggtcgtgta tccttcatgt aagggtttga cttggtacag gccacattcc aatgaacgaa
    27901 cctttcctta tacttatctg cgataactag agatggaacg atctggccgc aataattcag
    27961 cctcgcttat tccaaggtca tcaggcccta tcgtctcact ggagcagctg gttcttctgt
    28021 agcatgggta tccttacttc aactcacagg acaatggagt agttaacagg tttttgatgt
    28081 catctctgtc agggttaaat atcactggcc atgttgtggc ggaacaactt gtgatggacc
    28141 aagattgata tgcttgttga tttgtttttc cttgcatctg atctattcca tatcttagaa
    28201 ttccttatgt cacatcgtat cctttgcgtc gccttctgcg tttgttctct tgttgctgtg
    28261 agctcgattt atagcccccc gtaagctgct agcgtttcga agaacgtaaa tcaaaacgag
    28321 attataggtt taaccatccc attgtctaca gtaacaatgc catttgtttt cagctttcta
    28381 cttggcgcat tcctcagctg tatttggctg tccttatcag gaggttcgac ctgtcgctgt
    28441 cgaccagggg agtcatgttg gccgtcaccg tcggagtggg cagctctcaa caccactctc
    28501 agaggtgatt tagtcgaggt ccggcctatc gctcacattt gccatgaccc cttctatgat
    28561 cactctgctt gtcaaaactt gcgtgatctc gcaaaggaca gcggttggag agcctcacag
    28621 gccggtatgt tcattcgtct actcggtcat ttccttgaca cccatcccca tagcggcatg
    28681 ttgactgatt gcccgaatct ggcgaggtga cacactaggt accttacagg gctgggtttg
    28741 ggaggttggt cgcactgaag acgagacatg tcatgcgcat tctccgcgtg gtgcgccctg
    28801 tcatcaaggc cggattccac tgtattcggc ggcagttgag tctgttgacc aaattcaagt
    28861 ggcggtgagg tttgcgcaac gtcatcgact gcgcttggtt gttcgcaata ccggtcatga
    28921 taccgcggga cgatcgagtg gctccgactc gttccagata cattgccatc gcatgaagca
    28981 gatcgagtat catgacaact tccgggccct cggctccgat atagaccgtg gcccagccgt
    29041 gagcgtaggc gctggagtga ctctggggga gatgtatgca agaggtgccc gtgatggatg
    29101 ggtggtcgtc gggggggagt gtcctaccgt gggcgctgcg ggcggttttc tccagggagg
    29161 cggagtgtcc agtttccaca gcttcatcga cggtctggct gtagataatg tcctcgaatt
    29221 tgaggtcgtg acggcgaagg ttggtagata catccttgat aacttgcaat atggtgtctt
    29281 tgtactgaag ttcactatgg ctgtgtaggg agatgttgtc gtggccaatg accaccagaa
    29341 cccagacatc ttctgggctt tacggggagg gggtggaggc actttcggca tcgttacacg
    29401 tgctacaatg agggtgcatc tcaatagccc ggtctgcgtc tcggaggtgg cagtatcagg
    29461 gctccggaat aactcgttgc tctggacaaa agggatcacg ggtctatttt ccattcttcg
    29521 ctcgttcaac cagcagggga taccgggcca gtttattctt cgaccgctat ccaaggatca
    29581 ggtcaacgca agtctcacac tgtattccct aaacacagat gacactcgac gatcggccga
    29641 gaacatgctc tccattcgaa atatcctcga atctaccacc cttcccttca ctctggcctc
    29701 caggtgccta ccaaagatca gtgacgcgct ccgaaaagga cctgatatgc ttcccgtaaa
    29761 ttacggaatc atcaccggct ccgttttggt gtcagaggat ctcttcaatt cggaggaagg
    29821 accactgcat ctggccaagc agttggaaca tttcccgatg ggaccgatgg atctcctgtt
    29881 caccagcaac ctcggcggaa acgtttcggc aaacaccgga aagaagcaca gggatacctc
    29941 gatgcatccg ggctggcggc aagcggccca cctcatcaac ttcgtgcgca gtgtgagcac
    30001 acccacagcg catgagaagg ccagaagctt agaagagctt catagcgtcc agatgcggca
    30061 actgtacgac attgaacccg acttcagagt gtcgtacagg aatttgggcg accctctgga
    30121 aagtgatgct gcacaggtct actggggccc aaattacaag cggctgctgg aaatcaagcg
    30181 gaagtgggac cctgaggacc tgtttttctc tcagctgggg gtgggaagtg aggggtggac
    30241 agaggaccaa atgtgtaaga gacagcaaag actgcagcaa atgcttcagt atctaatgtc
    30301 cagcattgcc cagcgggtat accgctaagt gcagatgttc ctctgactgg atggtcgtgc
    30361 tgcacatggc tgtaagggat ggtcggtcag atattggact gtggtaaggg caatagcagt
    30421 acagtcaaca gcagtaacac atttgacaat actttacaat caagatgtat gtagataaag
    30481 gaaagaatgg gggaaaaact caaaggaggt agacaaagat gctctctata tcatcgttgc
    30541 ccaccagacc atcatattct tctttagact aagaatcagc caccatgacg atttcagctc
    30601 ctcccattat tgatatccgg caagcggggc ttgaaagctc aattcctgac caagttgtcg
    30661 aaggtctcac gaaagaagtg aaaaccctcc cagctctact tttctacagc acgaagggaa
    30721 ttcagcactg gaaccgccac tcccatgctg ccgactttta tccccgacat gaggaactat
    30781 gtattctgaa agccgaggct tcaaagatgg cagcatctat agcccaggat agtctcgtca
    30841 tagatatggg cagcgcgtaa ggacatgttt cctccggttc agcgagtcaa tagtaaatag
    30901 aagggcgctg accttcatcc tcttacagaa gtatggacaa ggtcatctta ctgcttgagg
    30961 cgcttgaaga gcaaaaaaaa tccattacat actacgccct tgacctcagc tactctgagt
    31021 tggcctcgaa ctttcaggcc atacctgtgg accgcttcca ttacgtccgt tttgctgccc
    31081 tccacggcac atttgacgat ggtctgcatt ggcttcagaa cgcaccagac atccgaaacc
    31141 gtcctcgttg catccttcta tttggtttaa ctatcgggaa cttttcacgc gacaatgcag
    31201 caagtttcct gaggaatatc gcacaatctg ccctctccac atcacccacg caaagctcta
    31261 tcattgtaag tctcgacagc tgcaaattgc ccaccaagat tttacgcgcg tacactgcgg
    31321 atggagtagt tcccttcgca cttgcgtcgt taagttatgc caactccctg tttcacccca
    31381 agggcgacag aaaaattttt aacgaggaag attggtactt ccatagtgaa tggaaccatg
    31441 ccctaggacg gcacgaagca tctctaatca cgcaatccaa ggacattcag ctgggtgctc
    31501 ctctagagac tgtcatcgtg cgcagggatg agaagatccg ttttgggtgc agttataaat
    31561 atgataaagc cgaacgggac cagctctttc actccgctgg tctggaggat gcagctgtat
    31621 ggacagcccc agactgtgat gtggcatttt accagttgag actgcgtctg aactgaacta
    31681 tggcctgttg gattaatata tcagatattg ctacccatca cagaagttta tgtagctaca
    31741 gaggagctcc ccagggccct gtcctcctaa taagtcttgg attcctttgg gtcccccttc
    31801 cccacatagg cttttttttg cgcttgaaaa atcatgggtg aatagaacct gttagactag
    31861 ttgtggtttg ggtttcggtc aacctatagc aaaaaaaaaa cccaccaatg ggctggttgg
    31921 gttctgggaa ctaggcctgt taacaataaa cagtcgcaga tttgtgcaaa aatcttggtg
    31981 aatgggcggc cgacccacat atactttatg ggctgctcca gcaatgtgtt gccagcaaaa
    32041 ggaggtcgag gcgcggtata tattcaaccc aatcattagg gcctaaactt tagtggatat
    32101 atacatatgg caaagatgca acttctgttt gatatctagg agtgaaacta acacatcaca
    32161 ctcattaacc tgtcacaggg tcaaccccca taatggttta gattaaggta cactccttaa
    32221 actcacaggt tgcatacagg cccaaacctt caatgtatat agatttcttg ggtaaattgc
    32281 aggctagcaa acagtacata catgatgtat aaaccaaaca tatagatcta ttggtatttt
    32341 atgcagacaa tatataccaa cttggaaaat ttatataaaa taagtatttg acagttaaca
    32401 tatgatcact gaaaaacctg cataggttac caggctttag gtacaggtcc tgaccctcaa
    32461 cctaacctac aggttctgtc actgtcctga gtcaagagtc ttgtaaatat atatcataat
    32521 aatatgcacc tttgcagtaa aatgaacaag accagctact aacaataaac agatgcaacc
    32581 ctgactgcaa acacatcagc tgcttattcc caatgatagg ctctctaagc acacttactg
    32641 ttctttaaag aaactgctta gtaggtaata ctgcagttaa ggaaagctgc tagagaacaa
    32701 tattagtaac gcatacttta cctgaaaata ataggaaacc atacacttgg agaagaaagc
    32761 atagctctca gcattctcaa gagcagaagc agagctcaaa ctatgcactg catcatagcc
    32821 atatgtctca ggaccgtaga tgccttttgt atgcgccagc tcatgtaaac tagaagttgc
    32881 ttgatccagg acactgcaaa tgtttgacca cgcaggaaaa tcggtaaagt acgcagggca
    32941 ggttcggact cttccgtagg ttccgtccgt gtcaccatag gcagtcatgg taaaagagtg
    33001 actgttagtg cattcaatgc cctctggagt gcagtagtag gttacaacgc cttggttccc
    33061 gttcgtggcc tctgtggcga tcgtgtctaa aacatccgca acatggttgc gggcctgcgc
    33121 gtcattggtc ttgaagaagc tctggaagag gctgtatgag tagtcggatt cgctgcggat
    33181 gaggctggcg cctgaattgg ccatttcggc cgcctgggtg agtgcgttgt tgattgctcg
    33241 aactccctca tcattgcagt tttcaagggt agcgcgtgta tccagagggc tggcaacagc
    33301 acccgcaatc agaggaagag caacaagggc ctggaagaaa tgcattttga tttactggta
    33361 agaaaagtct gatgttgctg aatgattaaa taatgagtaa ggattgacag tgacaaggat
    33421 gtaatctaat tgagagtata cataatagaa agaaatagtc aaaaagaagg gtatttacca
    33481 gacaacagat gtcaatctta tatatcatgt taaagttacc tgctagttta tccctgacag
    33541 atacaaccct gactgtttcc ttgtgtttgg ttaccatgcc tcaggatttt tgctgggtgt
    33601 ttcagactag attcactgga aaacagcaac aatgtcaaac acaacagacc catagtctag
    33661 atatgccgta cctactagaa gcagatttgc tgtggcaaag agacccttca gaaggttagg
    33721 aaattgtttt gcttttgcat tctgtaatat tatccagcct aggcacgcta ctactgctgc
    33781 tgtaccccta gcaattttaa gacatggatc tagcttacct ttacaagata agaaatttat
    33841 atcacagtta gaaagggttt tcaacgccta aggctgcaaa tagaagatgt tagaggtcac
    33901 atgctagatg ggtacatgat cttatactat tattgactgc tccaggcaga gtacgcagtc
    33961 tagaagaaag agaactactt acaatgtgcc agtctgaaac agtttagttt agagttctat
    34021 atagcatttt cgcccatgga gatccaatgt ttcagagcac ttccactcgc tttcctgtgg
    34081 aatagttcct tatccatact gacacgtgca gtgaatacgt aaagccacag ggcataggaa
    34141 agagacatgt ccatctgtat tccccgaagt cggcatgtta ctccagcttg atatccttgt
    34201 actcatacaa aactctatat tcctggaaga ctgtacttcg ctatttcttc taaatcttga
    34261 ctaggattaa tctaatgtct ggtttttaaa ggtatctaag agttatcatt acaaatgaaa
    34321 tcctgaattt tgtccttgtg gtgaatgttc ttaggaatta ggggttctat acaggtaccc
    34381 cacagaatat tagagcacct gtgcagatca taatgcaaaa gtacagggtc aagaaaatgt
    34441 tttagaatag tataacaaag tagatacaac aggcaggata caaagtcagg ccattgaaca
    34501 gatacatgaa ctgagacagg acgtggccct ggtttcaggt ttggatcgaa gctagatctc
    34561 aggaaaatgc agctagctgg gcaatcagaa aaacagcgaa aggcttcatc ccaatcgctg
    34621 atgcctagtc taagcggggc agggcactat gacgccaagt tccacgagat gccgagccgc
    34681 gcaatcctgt ttcacttcct tgtaatgtag aaaccacatc actaggagcc cctggttaag
    34741 gatctacttc attaatatag atcaacctat ttacaagggc gatcattgcc atgtagcgcc
    34801 aacgataagg gaccgaatag tcaaagtagt gcaagactaa tccttgggaa ccccccgggc
    34861 cggatcatct tgaatgcatc tgcggggact tatgattcag ttttgatgat agggtcatga
    34921 cgaggtcaat gttaggggaa aattacctta gtctaaggca actgtatatt gggcacaaga
    34981 aggttgactt gataggcaaa agaggagaag ggggaatgtt gtttgaagcg aaatgagagt
    35041 ggggcttgta taagggtagt tcttggtcca gtaacaagca tggcaatgaa aatctaaaca
    35101 tacaaggagg tttaaattaa agggcatgtg tataggaagc atatatcaag aatgtagtct
    35161 tatgtagata gggtgtcatg gtgctgctgt ggataggagt tggcgttgct aaggaggaat
    35221 tatataactc taggaatatc tttactatat aatttagcaa cctatttaaa gatctttaag
    35281 ctacatcctg tctatagagc ctgcctatac tagtctaacc tataactaga atagatagat
    35341 atagactact atagctagtc taagtattaa ctaccttatt aacctatttc tatttactta
    35401 taatctagta ccttaacatt atatagctcc acccttggag ttaatactat tagaatacct
    35461 aaccctctgc ccctattcct acctagtaac cctaaagagt tctctaagta tattactagc
    35521 tatagtacta aatagtataa atactactac ctagtatata agtatatcta gaagactaaa
    35581 ttaactatta ataaagtaaa ctaataagct aaataatcta aggcctaact tctaaaactc
    35641 tagtataaac tcactgcctt aaagcagaga tattaataag agactactaa gctaagggct
    35701 gtcctataat actagaagga atagttataa gagaaagagt agtagtatat aaaagctatt
    35761 ataaaaagag actaagccta ttacttagct acccctatta taaatatacc tatacctata
    35821 cctatgcata actctattac taaaaagcct atagttactc tagtaagaat atctacatta
    35881 gctactaccc tatcttctaa agctactaga ttattagaat aactctctaa ccctaataag
    35941 tttaagagta actaaaagga cctttagtat ttcatagtat agatttaaga gaaaataaat
    36001 attaacctta actacttcct aatactgcag agctagatag cttatataaa taactatcta
    36061 aagggtatgc ctaataccta gattctcctc tatattaaga agggaattta tacccttaat
    36121 aactactaag acatcctaga tatcctagag cacgccttta gtaaccctaa ctatataaat
    36181 aatgcctaaa ataagctatt tagcctatgc tagactaata aagagtttag taccttcttt
    36241 atagaatttt aatgcctagc cctagaaggt gagataccta aagaaaccct atttatccta
    36301 cttaaatagg ctattagtta taaactctaa agtatactta tatataacta gcctctaagc
    36361 tagaagtatt actagtttac tagactctta tagaagctta agaactacta ctagtaatat
    36421 actactaact agccctttat tattaagacc tatgctatta ctgctaaacc tacctagtat
    36481 ctttagttat tctaaagctt aagccctatt attactaagt ctactaagta accctagcac
    36541 cctattattt agaggaataa gcatatacta gtatattaat ataaccctat agatctaggt
    36601 actacctaat acctaataag aaagaggtat agcctctcct actaaataat aggtacctac
    36661 ttctaatata gctccctaga atactagatt agggactacc cccaccctaa tacctcttaa
    36721 agagtttaaa ttatagcatc ttataaacca tatctagaga gcccctaaag gggatagatc
    36781 ctagaatcta gaagcttatt acccagccag acctccttag taaaagaagt aagcctagag
    36841 taagctataa ctaggcttag gaactatata ttatttaaat ctctgctgcc actgtttatg
    36901 gacttaactt taaaaaataa atataataat taaaagctat aatactacct ataaccctag
    36961 agaaggaaga gaaaaggata aagctatcta cttataccct attaaatacc aaagctaaag
    37021 aataagaatt tattaataaa ggataggcta aagattagta gctagagcct atccccctag
    37081 cagacctaat aaccctatat atatttaata ggagagaact agagaatagg aagataacct
    37141 attatattta gatagatata agaattaaga actactttaa gaaagatata aagttttata
    37201 ttatctagtt agcatactac cctattatac taggaatacc ttagataaag gtatataacc
    37261 ccctaatata attcacagcc tatagtatta tgtttaatag taactactat tagaaatact
    37321 ataatactcc ctagaggcta actaagatat aagccctgca taacatcccc ctaaagacct
    37381 agcctaaata cctaccccta aaactaaagg gactagagaa tagagatata gcttttatct
    37441 ccttagcagc ctgcttagct tacacctaga gaaataccta gatatttata attaccctag
    37501 aagatcttaa agctacccta aggattaaga aagcttagaa agaagacttc actaacctat
    37561 tacctaaaga atttaaagat tatactaata ttttctctct taaggaggct aagtacctac
    37621 tactatacta cccttataac tataatatta agctattaga gggaaagacc cccctattta
    37681 gccctctgta caccatgtcc taagagaaat taaaagtcct aaaggaatag attaaagaga
    37741 acctaagaaa gggctttatc taccctagtt tatcacctgc tgtgttgcct atcctattta
    37801 ttaaaaagct aggtagaggt atataaatct atattaatta ctaagcccta aatactataa
    37861 ctattaaaga ttaataccta ctacccctaa taaaggaaac cctaaataac ctaaaaggga
    37921 tgaaattgtt acagcactga cacagccaca ctagcgcaag gcggatgtaa caggcagaaa
    37981 cccaaagatc aatgatcacc agtcaatccc ggagtgatta gggcatgatc tagagaaatg
    38041 cttaatccag ataggtttct acagaaaaac agtttagtag ttgcttacta aacattaatg
    38101 cttacataat gaggtgcacc ctcaaggagt acctcacgtg actaagggta tatggatggt
    38161 atgccaagac aacattattg aggtatatga tataccacca ccatacccag gatataccac
    38221 cgaatatact aactggagga actctagata tataaggcac tcactcacat tgtatctaga
    38281 actcttagct tagttccttg tatttaataa atatatctca cttaagtaca agttcactag
    38341 tccgattcgt cagttactct ctactattaa gtatatatac tcaataggcc ttgcttctat
    38401 ctctactatt attgttctta tgttaccttt ggttgtcttt gatccctaga tagatcatta
    38461 tatcattaca tcattaggct atctaattaa tagtcctcag gcaagtatcg gatatagtcc
    38521 agggactata tcaccccgtt cccaaagtag ttgactagca gagaacagca gagacagatc
    38581 ccagggtgtg acagaaatat tttataaaga ttaatattat tttagtattt aataatatct
    38641 gtattaagaa aggataagaa tacctaatag ctttctatac ctaactaggc ctatttaaat
    38701 tcttagtaat actctttagg ctgacagaaa cacctgtaac cttttagtaa tttattaata
    38761 atatcttata agattacctt aatatcttct atactgccta tcttaataat atcctagttt
    38821 atagtaagat atactctaag tatataacct atatttactc tatcctatag aaactataag
    38881 aagctagcct atatacaaaa atccaaaagt ataagtttat tatccccaaa actaagttcc
    38941 taggtattat tattagctag gatagcatct gtatagaccc taataaagta aaaataatta
    39001 ttaactagta agttctaacc tatattacta atatttaggc ctttattagt tttagcaact
    39061 tttactagga atttatcaag gatttcttaa gaattattat tcccttagtg aacctaacta
    39121 ggaaggatgt cctatttata tagactataa cctataaatt aagctttaaa gccctgaaga
    39181 aggtatttat aaatgcccta atcttaaaac tatttaacta gataaaagat gttatagtta
    39241 agactaactc ttctaattat atatctacta atataatatc ctagtataat aataaggaag
    39301 tcctgtatcc tattatattc ttctctaaga agctcttagt tactaagtat aactataaga
    39361 tctataataa agagttactc accattattc actattttaa ggaatggcgc cctaaactag
    39421 agggtatact attactaatt aaagttataa ctaattacta taacctagaa tattttatgt
    39481 ctactaagct gcttaataga tgacaagcct actagtataa attcctatcc tactttaact
    39541 ataaaattat atattaatct aggaagtaag gagttaagcc tgatactcta actagaaggt
    39601 tagaagatct ccctaaagag ggggataaat agctacaaca ctagagccag acaattctaa
    39661 agaaaaagaa ccttaaccct aaaatttaga actttgtaaa actagaagcc attataagga
    39721 gctagactaa cctaaaccta actagaaata gctagttagc tataagaaga gtttgcttta
    39781 tagatctagt agcctaagtt actaaaatac ctaaggaacc taccagagtg cctgcttaac
    39841 cagcttagac agactaacta gactaatcag actaaccaga ctaactagac taactagact
    39901 aattaaacta accagaccaa ccagaccaac cagaccaacc agaccaacca gaccaactag
    39961 accaactaga ctaaccagag ccccctccta gtattaagga actactagat actgcctact
    40021 agttagataa tactatacag tccatcctac aagcactaga taggaatgct agtttatgaa
    40081 agaaaataaa tagtatatac taaatattat atgaatgaca aaggaaattt cacgaatata
    40141 gaggggaata gatggcttgc ctaggtatag aggaagaata ggaagaataa tagtaggaga
    40201 aaaatctaag gatgtcttag attaatgtct tgattcctta attaattata ttctagctat
    40261 agggtgattt caagggtgta tttatagata attccttcta gcataggcca ttcgaatatt
    40321 aaatgatctc atagccgggt gatctcatca attagatcac catttgctaa tggttgaaat
    40381 cgatgatgat tgatgatgat ctataaccat aaggttagaa ccgtagcgga tcaacccatg
    40441 ggtatgatca acgatcaatt atagcatggt tttcaccaac atagttaata ccctaagatc
    40501 accctagcta attacagatg atgaggaagc tatttatact actataaata cttatatatc
    40561 ccctgactat aataagctga gagcctagtt attataagaa tgctataata agcctgctat
    40621 tagacaccct ggaaagtata agttatataa gttaatagta taagaatatt actagccagg
    40681 tatgtactaa tatattaatt attagaccta aaactattat atctactgct aatctacctc
    40741 atcctataaa gcctactaag gagtgctata tctactccta gtacctaaat aatcatagta
    40801 agatatctta atagacttta ttattagtct agtacctagt taaggctatg atgctatact
    40861 aattattatt aattaactta taaagataag atactttatc ccctgtcaga ctacctataa
    40921 tgctaaaggt atagcctaat tatatatcta ttatatatag aagctatatg gcctactaag
    40981 aataatagta ttagattata gcccttagtt tgttgctgtg ttctagaagc acctaaccta
    41041 acacctagat attaagaacc tattatctac tacttactac cctaagacta atagctaaag
    41101 taaaaggatg aatactattc tagaataata cctatatact tatattacct atttataaga
    41161 tgattaggct gactggttac tattagctaa gtttacctta aactctatct aatctaaggc
    41221 tactagaacc tcactcttct ttataaatta tagatttcac ctatgcatag ggtttgaacc
    41281 tatctagcct ataaatcacc ctactactaa agatactaag gcctttataa agaaaatata
    41341 agatgttatt aactatatct acacctagat ctatattacc taggcctgtt ataaggaata
    41401 gatgaattac tactagagac ctgcctacta ttactatata gaatagctag tttagttaga
    41461 cacctaaaat atcaggaccc tgcaccccta gaagaagctt aactagaaac acctagggct
    41521 attctatatt aagaagatta ttagcctata tatctataag ctagatctac cagcttctat
    41581 aaagattcac cctatattta atattagctt actacatcct attactaaag accctattcc
    41641 tagataaaga taactactac taccactagt agaagttaat agcctagaag aatagattat
    41701 taagaatatc ttagattcct actaggaaca ctagggctga taaggcccct atctaaagta
    41761 tactattaaa tagttaggct ataataacct cactaaggaa cctacctatt acctaaggaa
    41821 tatataaaag attatagcta acttctacta ctactaccta agtaaaccta aactagtaga
    41881 tagtcttaat agagcttaac cctaaggagg ggagtactgt tatagtacta ctgtggatag
    41941 gagttagtat tactaagaag gaattatata actctaggaa tatctttact gcataattta
    42001 gtaacttttt aaaggtcttt aagctatatc ctgtctatgg agcctgccta tactagtctg
    42061 ccctgcaact ggaatagata gatatagatt actatagcca gtctgagtgt taactacctc
    42121 attaacctat ttctgtttac ctgtgatcca gtaccttgac atattcctta actaagacag
    42181 cctactatag attactctac tacctttaat ctaaatagga taagagacat atcattctaa
    42241 tcagcacatt tttcttaatt tttagacata ttaattatcc ttagattata atataataat
    42301 actcaaatag gattgtaata gaaatttaag agtagttagc gtgctttagg atactaatta
    42361 cttttgaatt tctgttatat atctttacct ataaatatct ccaccactcc tggatatttt
    42421 ttaataataa tactattatt taattcctct cttcaagctc tattaaatgg tgtatatttc
    42481 attaagatta gttgtggttg tgttgttgac ctaaacctag aactccctat atagacaagt
    42541 actttgatgc gctcttctcc aggccagtca gatggaaggg agcgctcgcg ctttaactgt
    42601 gagaacttag tcccaagata tagagcgata tcatgctgaa tcactggttc agatatctca
    42661 tggaggatca attcctggtg gtcatcggtg atgctgttca actcga
//
