LOCUS       CM000169               46683 bp    DNA     linear   CON 23-MAR-2015
DEFINITION  Aspergillus fumigatus Af293 chromosome 1, whole genome shotgun
            sequence.
ACCESSION   CM000169
VERSION     CM000169.1
KEYWORDS    WGS.
SOURCE      Aspergillus fumigatus Af293
  ORGANISM  Aspergillus fumigatus Af293
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
REFERENCE   1  (bases 1 to 4918979)
  AUTHORS   Nierman,W.C., Pain,A., Anderson,M.J., Wortman,J.R., Kim,H.S.,
            Arroyo,J., Berriman,M., Abe,K., Archer,D.B., Bermejo,C., Bennett,J.,
            Bowyer,P., Chen,D., Collins,M., Coulsen,R., Davies,R., Dyer,P.S.,
            Farman,M., Fedorova,N., Fedorova,N., Feldblyum,T.V., Fischer,R.,
            Fosker,N., Fraser,A., Garcia,J.L., Garcia,M.J., Goble,A.,
            Goldman,G.H., Gomi,K., Griffith-Jones,S., Gwilliam,R., Haas,B.,
            Haas,H., Harris,D., Horiuchi,H., Huang,J., Humphray,S., Jimenez,J.,
            Keller,N., Khouri,H., Kitamoto,K., Kobayashi,T., Konzack,S.,
            Kulkarni,R., Kumagai,T., Lafon,A., Latge,J.P., Li,W., Lord,A.,
            Lu,C., Majoros,W.H., May,G.S., Miller,B.L., Mohamoud,Y., Molina,M.,
            Monod,M., Mouyna,I., Mulligan,S., Murphy,L., O'Neil,S., Paulsen,I.,
            Penalva,M.A., Pertea,M., Price,C., Pritchard,B.L., Quail,M.A.,
            Rabbinowitsch,E., Rawlins,N., Rajandream,M.A., Reichard,U.,
            Renauld,H., Robson,G.D., Rodriguez de Cordoba,S.,
            Rodriguez-Pena,J.M., Ronning,C.M., Rutter,S., Salzberg,S.L.,
            Sanchez,M., Sanchez-Ferrero,J.C., Saunders,D., Seeger,K.,
            Squares,R., Squares,S., Takeuchi,M., Tekaia,F., Turner,G., Vazquez
            de Aldana,C.R., Weidman,J., White,O., Woodward,J., Yu,J.H.,
            Fraser,C., Galagan,J.E., Asai,K., Machida,M., Hall,N., Barrell,B.
            and Denning,D.W.
  TITLE     Genomic sequence of the pathogenic and allergenic filamentous fungus
            Aspergillus fumigatus
  JOURNAL   Nature 438 (7071), 1151-1156 (2005)
   PUBMED   16372009
  REMARK    Erratum:[Nature. 2006 Jan 26;439(7075):502. Lafton, Anne [corrected
            to Lafon, Anne]]
REFERENCE   2  (bases 1 to 4918979)
  AUTHORS   Nierman,W., Wortman,J., Pain,A., Anderson,M.J., Arroya,J., Hall,N.,
            Barrell,B., Fraser,C. and Denning,D.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-MAY-2005) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
COMMENT     ##antiSMASH-Data-START##
            Version     :: 8.0.2
            Run date    :: 2025-07-23 12:25:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start :: 4872296
            Orig. end   :: 4918979
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     region          1..46683
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="7"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..46683
                     /SMILES="C([*])C(-O)(C)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..46683
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[30000:37960](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="30000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      30001..37960
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="30000"
                     /product="T1PKS"
                     /protocluster_number="1"
     mobile_element  complement(4654..7050)
                     /mobile_element_type="transposon:gypsy transposon family"
     repeat_region   12357..12381
                     /rpt_type=tandem
                     /rpt_unit_seq="tgctactcc"
                     /satellite="microsatellite"
     repeat_region   12527..12550
                     /rpt_type=tandem
                     /rpt_unit_seq="taa"
                     /satellite="microsatellite"
     repeat_region   15241..15382
                     /rpt_type=tandem
                     /rpt_unit_seq="cta"
                     /satellite="microsatellite"
     repeat_region   15259..15349
                     /rpt_type=tandem
                     /rpt_unit_seq="tac"
                     /satellite="microsatellite"
     repeat_region   15259..15374
                     /rpt_type=tandem
                     /rpt_unit_seq="tactacttc"
                     /satellite="microsatellite"
     mRNA            join(<21952..22341,22430..>23329)
                     /locus_tag="AFUA_1G17710"
                     /note="transcript AFUA_1G17710A"
                     /old_locus_tag="Afu1g17710"
                     /product="C6 transcription factor, putative"
     gene            <21952..>23329
                     /locus_tag="AFUA_1G17710"
                     /old_locus_tag="Afu1g17710"
     CDS             join(21952..22341,22430..23329)
                     /codon_start=1
                     /locus_tag="AFUA_1G17710"
                     /note="encoded by transcript AFUA_1G17710A; similar to
                     transcription factor SirZ (GI:46403061) [Leptosphaeria
                     maculans] PUBMED: 15387811; GO_function: GO:0003677 - DNA
                     binding"
                     /old_locus_tag="Afu1g17710"
                     /product="C6 transcription factor, putative"
                     /protein_id="EAL91099.1"
                     /transl_table=1
                     /translation="MMNSERKLRAACDRCHELKNQCTRTGGPDSRCDRCKRLDIDCVYN
                     TSARMGRPRVSRPGSENHKGASSTRHSKRGAVQAGSQCGATAVPLPVDHVDLASAVHDR
                     SGGSGSDSSRSLEPVLGLLDPVPLSQDLELYSPDFAHPAHDDPTGGQGLGRGHGHAHRE
                     YHQVESLQQKYKEVPDFSESDLEMSEKGTAPIVKTTGADELLRLQFHLSNLLTGARESP
                     TRHQPAIDEVMMVCKELLELLPISAHCSSSDCGTTSKSGIGAGRPFTPASVNAGHPDPC
                     DGIGQPTQRGGGPFHPLRINYIAFLQVATSYAYALQLLDLAVDNLISRGGNLALVSLGT
                     FNLASQPAMSTSVGAYMISSMVHQLRDAISVLTPEYQHQQRPPPPHASSPNGLRAAAAT
                     ANNSIHVAVDMISQKETSLLDKLAQIMIKP"
     PFAM_domain     21982..22095
                     /aSDomain="Zn_clus"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00172.21"
                     /db_xref="GO:0000981"
                     /db_xref="GO:0006355"
                     /db_xref="GO:0008270"
                     /description="Fungal Zn(2)-Cys(6) binuclear cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17710_0155"
                     /evalue="3.50E-05"
                     /gene_ontologies="GO:0000981: DNA-binding transcription
                     factor activity, RNA polymerase II-specific"
                     /gene_ontologies="GO:0006355: regulation of DNA-templated
                     transcription"
                     /gene_ontologies="GO:0008270: zinc ion binding"
                     /label="AFUA_1G17710"
                     /locus_tag="AFUA_1G17710"
                     /protein_end="48"
                     /protein_start="10"
                     /score="24.0"
                     /tool="antismash"
                     /translation="ACDRCHELKNQCTRTGGPDSRCDRCKRLDIDCVYNTSA"
     mRNA            <23771..>24514
                     /locus_tag="AFUA_1G17720"
                     /note="transcript AFUA_1G17720A"
                     /old_locus_tag="Afu1g17720"
                     /product="oxidoreductase, putative"
     gene            <23771..>24514
                     /locus_tag="AFUA_1G17720"
                     /old_locus_tag="Afu1g17720"
     CDS             23771..24514
                     /codon_start=1
                     /locus_tag="AFUA_1G17720"
                     /note="encoded by transcript AFUA_1G17720A; similar to
                     GB:BAC20563.1: oxidoreductase MlcF [Penicillium citrinum]
                     PMID: 12242508 PMID: 12172803; GO_function: GO:0016788 -
                     hydrolase activity, acting on ester bonds; GO_process:
                     GO:0008152 - metabolic process"
                     /old_locus_tag="Afu1g17720"
                     /product="oxidoreductase, putative"
                     /protein_id="EAL91100.1"
                     /transl_table=1
                     /translation="MSPETKPAIICLHGHGSNGEIFQAQSQNLTRVLSPRFRFVFLDSP
                     ITTAQTGVGVPPYYAHIKPYRRWHQDRNTIGLFDVTAEDVERERRAVRDSLKDVIERER
                     RNGPGAGVVGVMGFSQGTRVATAVCLDSELGRDIRFAIMICGICPSLALSAAETQVSRP
                     LDIVPVHVQGSGDPWLAKGTRLSKQYFNQRLATVVRFKGRHEIPVTTSDVQNIAEVMAE
                     YWEQKRDTVLAVEVASEFAARMVSA"
     PFAM_domain     23783..24415
                     /aSDomain="FSH1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF03959.16"
                     /description="Serine hydrolase (FSH1)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17720_0156"
                     /evalue="1.90E-28"
                     /label="AFUA_1G17720"
                     /locus_tag="AFUA_1G17720"
                     /protein_end="215"
                     /protein_start="4"
                     /score="99.7"
                     /tool="antismash"
                     /translation="TKPAIICLHGHGSNGEIFQAQSQNLTRVLSPRFRFVFLDSPITTA
                     QTGVGVPPYYAHIKPYRRWHQDRNTIGLFDVTAEDVERERRAVRDSLKDVIERERRNGP
                     GAGVVGVMGFSQGTRVATAVCLDSELGRDIRFAIMICGICPSLALSAAETQVSRPLDIV
                     PVHVQGSGDPWLAKGTRLSKQYFNQRLATVVRFKGRHEIPVTTSDVQN"
     mRNA            complement(join(<24611..24798,24852..25433,25611..>25896))
                     /locus_tag="AFUA_1G17723"
                     /note="transcript AFUA_1G17723A"
                     /product="aldose 1-epimerase family protein, putative"
     gene            complement(<24611..>25896)
                     /locus_tag="AFUA_1G17723"
     CDS             complement(join(24611..24798,24852..25433,25611..25896))
                     /codon_start=1
                     /locus_tag="AFUA_1G17723"
                     /note="encoded by transcript AFUA_1G17723A; similar to
                     UDP-glucose-4-epimerase, catalyzes the interconversion of
                     UDP-galactose and UDP-D-glucose in galactose metabolism;
                     also catalyzes the conversion of alpha-D-glucose or
                     alpha-D-galactose to their beta-anomers; Gal10p
                     (GI:6319493) [Saccharomyces cerevisiae]; GO_function:
                     GO:0016854 - racemase and epimerase activity; GO_process:
                     GO:0019318 - hexose metabolic process"
                     /product="aldose 1-epimerase family protein, putative"
                     /protein_id="EBA27420.1"
                     /transl_table=1
                     /translation="MNLWKFSVGLLAAVKSVWTRGSPFAALTALWPTNEEGKFIIQSEG
                     IRLAFTNHGAALTNLWLNNTHGEEVDVLLGLDYARGYPSLQSNPYLNGVIDKGWGRQTW
                     DIAVHISNSITFVLFDNRWNGFPGIFASCVTHTVTPYEWRIAFGVTPLLKAGPINFSQQ
                     VFFNLDGFRGNASTSDASDSTVLNHRPRLPSSGMRFDVDEWGIPTGDMKSNREGKEFDF
                     WSADKFIGDEVQKGNAGSDVTYVLSHKPLGDKEDEPVAILSSKPSGVTMELYTDQDALH
                     VHTWNSDLAGLRLKKGQGQGKVAQHAAISLEMQDWPDAVHHPEWRHRETIWGMDGLYTR
                     FATYKFSVERR"
     PFAM_domain     complement(join(24689..24798,24852..25422))
                     /aSDomain="Aldose_epim"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF01263.23"
                     /db_xref="GO:0005975"
                     /db_xref="GO:0016853"
                     /description="Aldose 1-epimerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17723_0157"
                     /evalue="5.20E-21"
                     /gene_ontologies="GO:0005975: carbohydrate metabolic
                     process"
                     /gene_ontologies="GO:0016853: isomerase activity"
                     /label="AFUA_1G17723"
                     /locus_tag="AFUA_1G17723"
                     /protein_end="326"
                     /protein_start="99"
                     /score="75.4"
                     /tool="antismash"
                     /translation="GRQTWDIAVHISNSITFVLFDNRWNGFPGIFASCVTHTVTPYEWR
                     IAFGVTPLLKAGPINFSQQVFFNLDGFRGNASTSDASDSTVLNHRPRLPSSGMRFDVDE
                     WGIPTGDMKSNREGKEFDFWSADKFIGDEVQKGNAGSDVTYVLSHKPLGDKEDEPVAIL
                     SSKPSGVTMELYTDQDALHVHTWNSDLAGLRLKKGQGQGKVAQHAAISLEMQDWPDAVH
                     HPEWR"
     mRNA            complement(join(<26084..27234,27303..27549,27614..>27877))
                     /locus_tag="AFUA_1G17725"
                     /note="transcript AFUA_1G17725A"
                     /old_locus_tag="Afu1g17725"
                     /product="cytochrome P450 oxidoreductase, putative"
     gene            complement(<26084..>27877)
                     /locus_tag="AFUA_1G17725"
                     /old_locus_tag="Afu1g17725"
     CDS             complement(join(26084..27234,27303..27549,27614..27877))
                     /EC_number="1.14.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_1G17725"
                     /note="encoded by transcript AFUA_1G17725A; similar to
                     GB:AAN74818.1: Fum15p {Gibberella moniliformis;};
                     GO_function: GO:0016491 - oxidoreductase activity;
                     GO_process: GO:0008152 - metabolic process"
                     /old_locus_tag="Afu1g17725"
                     /product="cytochrome P450 oxidoreductase, putative"
                     /protein_id="EAL91101.1"
                     /sec_met_domain="p450 (E-value: 3e-66, bitscore: 220.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPHLLKKLFTQFLFQQPFSMISFLGLWLCTVTLASGGIFHQALAG
                     GEHTALHFQVLGAHVVAFVAFAVYWMILYPRYFTPFGNIPTPSRRRILTGNYPVLFPDN
                     AWVPLRELAETTPNDGLLRIYSALSGEALLVTSPPAIRDMLTVNAFDFTHQDLVKIAIR
                     RFTGSNLERTQLHRKNMMPAFTVPHVRKLTSIFWAKAQEMVRCMSNELRADSFARIDFR
                     EYMSRATLNNIGLAGMGHDFQTLKQPDTDLRSHHRKLILDPTRVFSWVGLLSRYFDMRL
                     LMRVPLKKLIEISQSAKYLRELTTAVIQGRREQLVVAENNRGKDIITVALAGGVFDEHH
                     LVDHVMTFLTAGHESTATAFEWTMYELGRRPEMQSRLRDELRATIGTDLAAVNFGLRVQ
                     NLPYLNAFCSEVLRCYPFSPIIVKVAQKETMLIGQRIPKGTVVLYSAEVSNHDKTLWGP
                     DADKFDPERWMGAKKAKSGGASSNYAMLTFGAGPRNCIGANFARATLECLVAAVLSTFE
                     IELANPDTAGRLKFGQTKKSAEGIYGRLKFVQPVEV"
     PFAM_domain     complement(join(26180..27234,27303..27312))
                     /ASF="active site cysteine inconclusive"
                     /aSDomain="p450"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00067.25"
                     /db_xref="GO:0004497"
                     /db_xref="GO:0005506"
                     /db_xref="GO:0016705"
                     /db_xref="GO:0020037"
                     /description="Cytochrome P450"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17725_0158"
                     /evalue="3.30E-65"
                     /gene_ontologies="GO:0004497: monooxygenase activity"
                     /gene_ontologies="GO:0005506: iron ion binding"
                     /gene_ontologies="GO:0016705: oxidoreductase activity,
                     acting on paired donors, with incorporation or reduction of
                     molecular oxygen"
                     /gene_ontologies="GO:0020037: heme binding"
                     /label="AFUA_1G17725"
                     /locus_tag="AFUA_1G17725"
                     /protein_end="522"
                     /protein_start="167"
                     /score="220.8"
                     /tool="antismash"
                     /translation="SNLERTQLHRKNMMPAFTVPHVRKLTSIFWAKAQEMVRCMSNELR
                     ADSFARIDFREYMSRATLNNIGLAGMGHDFQTLKQPDTDLRSHHRKLILDPTRVFSWVG
                     LLSRYFDMRLLMRVPLKKLIEISQSAKYLRELTTAVIQGRREQLVVAENNRGKDIITVA
                     LAGGVFDEHHLVDHVMTFLTAGHESTATAFEWTMYELGRRPEMQSRLRDELRATIGTDL
                     AAVNFGLRVQNLPYLNAFCSEVLRCYPFSPIIVKVAQKETMLIGQRIPKGTVVLYSAEV
                     SNHDKTLWGPDADKFDPERWMGAKKAKSGGASSNYAMLTFGAGPRNCIGANFARATLEC
                     LVAAVLSTFEIELAN"
     mRNA            complement(join(<28316..28859,28923..>29467))
                     /locus_tag="AFUA_1G17730"
                     /note="transcript AFUA_1G17730A"
                     /old_locus_tag="Afu1g17730"
                     /product="zinc binding enoyl reductase, putative"
     gene            complement(<28316..>29467)
                     /locus_tag="AFUA_1G17730"
                     /old_locus_tag="Afu1g17730"
     CDS             complement(join(28316..28859,28923..29467))
                     /NRPS_PKS="Domain: PKS_ER (21-251). E-value: 1.2e-21.
                     Score: 69.1. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17730_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="AFUA_1G17730"
                     /note="encoded by transcript AFUA_1G17730A; similar to
                     enoyl reductase LovC (GI:4959947) [Aspergillus terreus];
                     GO_function: GO:0008270 - zinc ion binding; GO_function:
                     GO:0016491 - oxidoreductase activity; GO_process:
                     GO:0008152 - metabolic process"
                     /old_locus_tag="Afu1g17730"
                     /product="zinc binding enoyl reductase, putative"
                     /protein_id="EAL91102.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.3e-13, bitscore:
                     47.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSELPSSQPAIIESDDGTLGLRNDVQMPSLEDDMILVRNAFVALN
                     PIDTKMVGKLASPGAIAGKDFAGEVVSIGPKVQTAAPIKPGDRICGAVPWMHSLTPAVG
                     AFAQYVGATDLTAIKIPEYMSLEEAVTLGSGIGTIGLALFKSLDVPGSPWLPADKPVDV
                     LVYGGSTATGTLAIQLLKLSGLNPITTCSPTKFDLVKSYGATAAFDYRQKTCADDIRKY
                     TRNSLKFVLDCISEPETMQFCYKCLGRWGGGGGGGGNTPHWNLTLSSYIPGRRRLCQIG
                     CLARRCWGKGLTGQSRLVGRGTRSTEGLGSSGLSWCRSWLDQGKLKTHPHKLVGDSLGE
                     ALGGLGLLKEKKVSGQKLVCRV"
     repeat_region   28631..28656
                     /rpt_type=tandem
                     /rpt_unit_seq="c"
                     /satellite="microsatellite"
     PFAM_domain     complement(join(28649..28859,28923..28954))
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00107.29"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17730_0159"
                     /evalue="1.60E-12"
                     /label="AFUA_1G17730"
                     /locus_tag="AFUA_1G17730"
                     /protein_end="252"
                     /protein_start="171"
                     /score="47.7"
                     /tool="antismash"
                     /translation="TGTLAIQLLKLSGLNPITTCSPTKFDLVKSYGATAAFDYRQKTCA
                     DDIRKYTRNSLKFVLDCISEPETMQFCYKCLGRWGG"
     aSDomain        complement(join(28652..28859,28923..29404))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17730_PKS_ER.1"
                     /evalue="1.20E-21"
                     /label="AFUA_1G17730_PKS_ER.1"
                     /locus_tag="AFUA_1G17730"
                     /protein_end="251"
                     /protein_start="21"
                     /score="69.1"
                     /tool="antismash"
                     /translation="RNDVQMPSLEDDMILVRNAFVALNPIDTKMVGKLASPGAIAGKDF
                     AGEVVSIGPKVQTAAPIKPGDRICGAVPWMHSLTPAVGAFAQYVGATDLTAIKIPEYMS
                     LEEAVTLGSGIGTIGLALFKSLDVPGSPWLPADKPVDVLVYGGSTATGTLAIQLLKLSG
                     LNPITTCSPTKFDLVKSYGATAAFDYRQKTCADDIRKYTRNSLKFVLDCISEPETMQFC
                     YKCLGRWG"
     mRNA            join(<30001..30950,31041..31271,31351..31806,31898..32953,
                     33086..33608,33684..33943,33979..35797,35894..36313,
                     36368..36600,36661..37385,37440..>37960)
                     /locus_tag="AFUA_1G17740"
                     /note="transcript AFUA_1G17740A"
                     /old_locus_tag="Afu1g17740"
                     /product="polyketide synthase, putative"
     gene            <30001..>37960
                     /locus_tag="AFUA_1G17740"
                     /old_locus_tag="Afu1g17740"
     CDS             join(30001..30950,31041..31271,31351..31806,31898..32953,
                     33086..33608,33684..33943,33979..35797,35894..36313,
                     36368..36600,36661..37385,37440..37960)
                     /EC_number="3.6.3.-"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (36-412). E-value:
                     2.2e-135. Score: 443.8. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17740_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (552-809). E-value: 6.3e-73.
                     Score: 237.7. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17740_PKS_AT.1"
                     /NRPS_PKS="Domain: cMT (1241-1448). E-value: 1.5e-70.
                     Score: 229.4. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17740_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (1927-2102). E-value: 1.7e-39.
                     Score: 127.6. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17740_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2226-2294). E-value: 2.9e-11.
                     Score: 35.5. Matches aSDomain:
                     nrpspksdomains_AFUA_1G17740_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /locus_tag="AFUA_1G17740"
                     /note="encoded by transcript AFUA_1G17740A; similar to
                     lovastatin nonaketide synthase (GI:5106755) [Aspergillus
                     terreus]; GO_function: GO:0008415 - acyltransferase
                     activity; GO_function: GO:0016218 - polyketide synthase
                     activity; GO_process: GO:0019748 - secondary metabolic
                     process; GO_process: GO:0030639 - polyketide biosynthetic
                     process"
                     /old_locus_tag="Afu1g17740"
                     /product="polyketide synthase, putative"
                     /protein_id="EAL91103.2"
                     /sec_met_domain="itr_KS (E-value: 5.1e-138, bitscore:
                     457.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.7e-71, bitscore: 237.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.3e-34, bitscore:
                     116.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-06, bitscore:
                     24.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNQSPLYAWAAVSQVKPAPPPNSGTSSTTRAMSPVTSPFNLDRFY
                     HPTGSHHGTTNIRQAYLLSEDVRAFDAKFFSVPPGDAEAIDPQQRLLLEVTYEALESSG
                     HTLADLSNSNTGAFVGLMSQDYFALNGQDVDSVPTYAASGTAASNASSRLSYFFNWHGP
                     SMAIDTACSSNLVAVNEAVQALRNGTSRVAVACGTNLCLSAFTFITLSKLSMLSPTSRC
                     HMWDADADGYARGEGVACVVLKTLSDAISDRDPIEAVTREVGVNHDGRTKGLTMPSAKA
                     QAALIRNTYARAGLDPTKEADRCQYFEAHGTGTKAGAFFPQSDSEGELFVGSIKAVIGH
                     TEGTAGLAGLMKACLALRNATFPPNLLFNKLNPDLELFTSHLRVPTANQPWPEFVNSFG
                     LGGTNAHCILETYNPPTASDPVIEIDMAASGTCCIPSVFSAASDRSLATLLQSTLKFMD
                     ENTDVNMSGLAYNLSTKRSALQRRLAVSATSIDELRDKIKSTIEAASENDATLHSTSAL
                     PEPASLLGIFTGQGAQWQGMGSQLISSIPTTPVGKASLSQPLCTAVQVILVDMLRAAGV
                     KFQAVVGHSSGEIAAAYAAGFISAWDAIRIADYRGFYAEMAAAPGGEKGAMLAAGTSFE
                     DASDLCQLDDFAGRICVAAHNSPSSVTLSGDIDAIALARRVLEEEEKFARRLKVDTAYH
                     STHMHKCSVPYLTALRNCNIQVQQPGPDAPQWFSSVRNGQVISSMESLDSQYWVDNMVQ
                     PELFCPAVQTCLKYVDKAINCVVEVGPHPALQGPAKDSILAAVDREIPYTGTLNRGKSS
                     TVAFSDALRFLWCLFGSAAVTLGAFQQTNYPDTPTTMTRGLPTYPWTHDRGYFAESRLI
                     KTFHNHPLPFHDLLGIQTADGAREEWGPVKSIDLFDLEIHKAIASHDSTGTELLTSMTK
                     VSALDTEWEEITADFSAYSTISKDAANLGLNCCGRVRVLLGEGEDSPSHFSPRLPPLGK
                     LTAVDVDSFYKILRDDFGFGYEGPFRALTNMSRKTGFATGTVRCERFDDSETSLLFHPG
                     MLDSALQGLNAAHSAPGDDRLWTIIDCNITDPRDTHITGDVEVFSEGFREKIIEVEGLT
                     FSPFASATVENDRCVFQESFLCHAKPNADVIFGDRQATPEESRKALFAERAAPEQREAL
                     PWYRQALLKNAELLLHLVNDGKHPFAPQNWVSDTREDIFKMMDSYPTTDADFNLTKAVG
                     EHLLLPSVLNGDTSILQYMTKDNYLERYYVDAIGFQLLNFLIAGVMEPLCLKSPRMNFL
                     EVGAGTGGATKAILEKIGYSYASYTYTDISSAFFDHDAGHFQSHASKMIFKALDITKDP
                     AGQGFIPQSYDVIVASNVLHATESLRSALEHTRRLLRPGGYLVMVEIIRNDVMRHGLVM
                     GGLPGWWVGENDGRYGGPSITLDQWHKMLRETGFSGIETNSPMRDPVGVPGSIIVSRAE
                     TDLVTQLTRPLSSKFSTATDKTPLLIIGGISPFVSPFRDQICLTLRRHFGDIIKVEQFA
                     DLPPLPECYHVLSLTECDANLFEDMEESVFLNLKTVLGSALSVLWLLRDRRSSNPHAGT
                     TLGLFRTLFYEVPGTLLQTLDIDVVNMDDCSVIAESMCQLRFQSDMARRGETDEIRWEF
                     EPELVLKDGELYVPRVRPHDGQNNRYNSSKRLITHNVDVHTTPLALDLVDGSYMVREQH
                     TIEKDSPEVATVNVSCSFLSSIKTPVGYVFVSLGENVKTGEKTLCFTNHNGSIVKVHKS
                     WTISLGEVEPDPVAASLLSWHLNGLGRKALFMTLSPEMCGRNWVYLHPNSTMRAIAANL
                     PADVTLYVDASGAGESPSQSLGSKIATSLSSVCNKVKMSSLTASEASFLPHDAPKTITD
                     LFRHVASFASSLVSTQATPEGAPLDILPLKRDQYVPVSVEPVTQRGDLFRPDRTYWLAG
                     LTGDTGRSLADFMIAHNARNIVLSSRTPTVYEDWVEWHKSRGVSVRYFGGDITSFQSVK
                     QIHDAIKESMPPIGGVANGAMVLRDSSFMKVSFDDFQAVLGPKVKGTINIDRLFSDPNQ
                     LLDWFIGFSSVAGTVGNPGQSGYTAGSCFIKALVDRRRKQGLAGSVIDITRLVGLGFIE
                     REGDGRLTKEHQERLTTRSGTIAMSENDLHQLFAEAILAGRPDLDLNPEIITGLAPITV
                     EQSKDTYWKTNPRLSLLIREAGQGDLKGRDGGNAAPLRQLLGDTKTMQNVANVLSGALK
                     GKLQALKFLSDSDSLYDTTPLVDMGVDSLVAVEVRSWFLKELTVDVPLMKILGGASITD
                     LVEVVVQKVPRELLSRLDPEGRRQDSNGDVPATVGDNDSVETVGSKMNGINSAHENGSS
                     GVNGISGTYTPDMDSTTDLNGTNGAAVIKEMLGHKAIKGVVPILLNAQEVA"
     aSDomain        join(30109..30950,31041..31271,31351..31405)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17740_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.20E-135"
                     /label="AFUA_1G17740_PKS_KS.1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="412"
                     /protein_start="36"
                     /score="443.8"
                     /tool="antismash"
                     /translation="SPFNLDRFYHPTGSHHGTTNIRQAYLLSEDVRAFDAKFFSVPPGD
                     AEAIDPQQRLLLEVTYEALESSGHTLADLSNSNTGAFVGLMSQDYFALNGQDVDSVPTY
                     AASGTAASNASSRLSYFFNWHGPSMAIDTACSSNLVAVNEAVQALRNGTSRVAVACGTN
                     LCLSAFTFITLSKLSMLSPTSRCHMWDADADGYARGEGVACVVLKTLSDAISDRDPIEA
                     VTREVGVNHDGRTKGLTMPSAKAQAALIRNTYARAGLDPTKEADRCQYFEAHGTGTKAG
                     AFFPQSDSEGELFVGSIKAVIGHTEGTAGLAGLMKACLALRNATFPPNLLFNKLNPDLE
                     LFTSHLRVPTANQPWPEFVNSFGLGGTNAHCILETY"
     aSModule        30109..37648
                     /complete
                     /domains="nrpspksdomains_AFUA_1G17740_PKS_KS.1"
                     /domains="nrpspksdomains_AFUA_1G17740_PKS_AT.1"
                     /domains="nrpspksdomains_AFUA_1G17740_cMT.1"
                     /domains="nrpspksdomains_AFUA_1G17740_PKS_KR.1"
                     /domains="nrpspksdomains_AFUA_1G17740_PKS_PP.1"
                     /iterative
                     /locus_tags="AFUA_1G17740"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     PFAM_domain     30112..30747
                     /aSDomain="ketoacyl-synt"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00109.29"
                     /description="Beta-ketoacyl synthase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0160"
                     /evalue="5.60E-58"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="249"
                     /protein_start="37"
                     /score="196.6"
                     /tool="antismash"
                     /translation="PFNLDRFYHPTGSHHGTTNIRQAYLLSEDVRAFDAKFFSVPPGDA
                     EAIDPQQRLLLEVTYEALESSGHTLADLSNSNTGAFVGLMSQDYFALNGQDVDSVPTYA
                     ASGTAASNASSRLSYFFNWHGPSMAIDTACSSNLVAVNEAVQALRNGTSRVAVACGTNL
                     CLSAFTFITLSKLSMLSPTSRCHMWDADADGYARGEGVACVVLKTLSDA"
     CDS_motif       30484..30531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0001"
                     /evalue="8.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="177"
                     /protein_start="161"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSMAIDTACSSNLVA"
     CDS_motif       30673..30711
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0002"
                     /evalue="3.60E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="237"
                     /protein_start="224"
                     /score="13.6"
                     /tool="antismash"
                     /translation="WDADADGYARGEG"
     PFAM_domain     join(30772..30950,31041..31191)
                     /aSDomain="Ketoacyl-synt_C"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF02801.25"
                     /description="Beta-ketoacyl synthase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0161"
                     /evalue="2.10E-21"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="367"
                     /protein_start="257"
                     /score="76.2"
                     /tool="antismash"
                     /translation="AVTREVGVNHDGRTKGLTMPSAKAQAALIRNTYARAGLDPTKEAD
                     RCQYFEAHGTGTKAGAFFPQSDSEGELFVGSIKAVIGHTEGTAGLAGLMKACLALRNAT
                     FPPNLL"
     PFAM_domain     join(31204..31271,31351..31597)
                     /aSDomain="KAsynt_C_assoc"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF16197.8"
                     /description="Ketoacyl-synthetase C-terminal extension"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0162"
                     /evalue="1.80E-09"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="476"
                     /protein_start="371"
                     /score="38.2"
                     /tool="antismash"
                     /translation="NPDLELFTSHLRVPTANQPWPEFVNSFGLGGTNAHCILETYNPPT
                     ASDPVIEIDMAASGTCCIPSVFSAASDRSLATLLQSTLKFMDENTDVNMSGLAYNLSTK
                     R"
     CDS_motif       31745..31795
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="542"
                     /protein_start="525"
                     /score="17.4"
                     /tool="antismash"
                     /translation="IFTGQGAQWQGMGSQLI"
     aSDomain        31917..32687
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17740_PKS_AT.1"
                     /evalue="6.30E-73"
                     /label="AFUA_1G17740_PKS_AT.1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="809"
                     /protein_start="552"
                     /score="237.7"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="ASLSQPLCTAVQVILVDMLRAAGVKFQAVVGHSSGEIAAAYAAGF
                     ISAWDAIRIADYRGFYAEMAAAPGGEKGAMLAAGTSFEDASDLCQLDDFAGRICVAAHN
                     SPSSVTLSGDIDAIALARRVLEEEEKFARRLKVDTAYHSTHMHKCSVPYLTALRNCNIQ
                     VQQPGPDAPQWFSSVRNGQVISSMESLDSQYWVDNMVQPELFCPAVQTCLKYVDKAINC
                     VVEVGPHPALQGPAKDSILAAVDREIPYTGTLNRG"
     PFAM_domain     31923..32633
                     /aSDomain="Acyl_transf_1"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00698.24"
                     /description="Acyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0163"
                     /evalue="3.80E-29"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="791"
                     /protein_start="554"
                     /score="102.3"
                     /tool="antismash"
                     /translation="LSQPLCTAVQVILVDMLRAAGVKFQAVVGHSSGEIAAAYAAGFIS
                     AWDAIRIADYRGFYAEMAAAPGGEKGAMLAAGTSFEDASDLCQLDDFAGRICVAAHNSP
                     SSVTLSGDIDAIALARRVLEEEEKFARRLKVDTAYHSTHMHKCSVPYLTALRNCNIQVQ
                     QPGPDAPQWFSSVRNGQVISSMESLDSQYWVDNMVQPELFCPAVQTCLKYVDKAINCVV
                     EVGPHPALQGPAKDS"
     CDS_motif       31983..32081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0004"
                     /evalue="6.50E-11"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="607"
                     /protein_start="574"
                     /score="34.6"
                     /tool="antismash"
                     /translation="GVKFQAVVGHSSGEIAAAYAAGFISAWDAIRIA"
     CDS_motif       32730..32786
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0005"
                     /evalue="2.70E-02"
                     /label="PKSI-KR_m4"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="842"
                     /protein_start="823"
                     /score="7.0"
                     /tool="antismash"
                     /translation="WCLFGSAAVTLGAFQQTNY"
     PFAM_domain     join(32934..32953,33086..33575)
                     /aSDomain="PS-DH"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF14765.9"
                     /description="Polyketide synthase dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0164"
                     /evalue="5.60E-15"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="1061"
                     /protein_start="891"
                     /score="55.5"
                     /tool="antismash"
                     /translation="GAREEWGPVKSIDLFDLEIHKAIASHDSTGTELLTSMTKVSALDT
                     EWEEITADFSAYSTISKDAANLGLNCCGRVRVLLGEGEDSPSHFSPRLPPLGKLTAVDV
                     DSFYKILRDDFGFGYEGPFRALTNMSRKTGFATGTVRCERFDDSETSLLFHPGMLDSAL
                     QGLNAAH"
     aSDomain        34226..34846
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17740_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.50E-70"
                     /label="AFUA_1G17740_cMT.1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="1448"
                     /protein_start="1241"
                     /score="229.4"
                     /tool="antismash"
                     /translation="QYMTKDNYLERYYVDAIGFQLLNFLIAGVMEPLCLKSPRMNFLEV
                     GAGTGGATKAILEKIGYSYASYTYTDISSAFFDHDAGHFQSHASKMIFKALDITKDPAG
                     QGFIPQSYDVIVASNVLHATESLRSALEHTRRLLRPGGYLVMVEIIRNDVMRHGLVMGG
                     LPGWWVGENDGRYGGPSITLDQWHKMLRETGFSGIETNSPMRDP"
     PFAM_domain     34352..34657
                     /aSDomain="Methyltransf_12"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08242.15"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0165"
                     /evalue="5.50E-19"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="1385"
                     /protein_start="1283"
                     /score="68.9"
                     /tool="antismash"
                     /translation="LEVGAGTGGATKAILEKIGYSYASYTYTDISSAFFDHDAGHFQSH
                     ASKMIFKALDITKDPAGQGFIPQSYDVIVASNVLHATESLRSALEHTRRLLRPGGYL"
     CDS_motif       36434..36532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0006"
                     /evalue="4.20E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="1960"
                     /protein_start="1927"
                     /score="35.4"
                     /tool="antismash"
                     /translation="TYWLAGLTGDTGRSLADFMIAHNARNIVLSSRT"
     PFAM_domain     join(36434..36600,36661..37015)
                     /aSDomain="KR"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF08659.13"
                     /description="KR domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0166"
                     /evalue="1.90E-42"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="2101"
                     /protein_start="1927"
                     /score="145.3"
                     /tool="antismash"
                     /translation="TYWLAGLTGDTGRSLADFMIAHNARNIVLSSRTPTVYEDWVEWHK
                     SRGVSVRYFGGDITSFQSVKQIHDAIKESMPPIGGVANGAMVLRDSSFMKVSFDDFQAV
                     LGPKVKGTINIDRLFSDPNQLLDWFIGFSSVAGTVGNPGQSGYTAGSCFIKALVDRRRK
                     QGLAGSVIDIT"
     aSDomain        join(36434..36600,36661..37018)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: False"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17740_PKS_KR.1"
                     /evalue="1.70E-39"
                     /label="AFUA_1G17740_PKS_KR.1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="2102"
                     /protein_start="1927"
                     /score="127.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TYWLAGLTGDTGRSLADFMIAHNARNIVLSSRTPTVYEDWVEWHK
                     SRGVSVRYFGGDITSFQSVKQIHDAIKESMPPIGGVANGAMVLRDSSFMKVSFDDFQAV
                     LGPKVKGTINIDRLFSDPNQLLDWFIGFSSVAGTVGNPGQSGYTAGSCFIKALVDRRRK
                     QGLAGSVIDITR"
     CDS_motif       36869..36979
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFUA_1G17740_0007"
                     /evalue="7.00E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="2089"
                     /protein_start="2052"
                     /score="50.8"
                     /tool="antismash"
                     /translation="LDWFIGFSSVAGTVGNPGQSGYTAGSCFIKALVDRRR"
     aSDomain        37445..37648
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFUA_1G17740_PKS_PP.1"
                     /evalue="2.90E-11"
                     /label="AFUA_1G17740_PKS_PP.1"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="2294"
                     /protein_start="2226"
                     /score="35.5"
                     /tool="antismash"
                     /translation="LKGKLQALKFLSDSDSLYDTTPLVDMGVDSLVAVEVRSWFLKELT
                     VDVPLMKILGGASITDLVEVVVQ"
     PFAM_domain     37481..37639
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF00550.28"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17740_0167"
                     /evalue="1.50E-05"
                     /label="AFUA_1G17740"
                     /locus_tag="AFUA_1G17740"
                     /protein_end="2291"
                     /protein_start="2238"
                     /score="25.3"
                     /tool="antismash"
                     /translation="DSDSLYDTTPLVDMGVDSLVAVEVRSWFLKELTVDVPLMKILGGA
                     SITDLVEV"
     mRNA            join(<38972..39352,39455..>40129)
                     /locus_tag="AFUA_1G17750"
                     /note="transcript AFUA_1G17750A"
                     /old_locus_tag="Afu1g17750"
                     /product="nicotinamide N-methyltransferase, putative"
     gene            <38972..>40129
                     /locus_tag="AFUA_1G17750"
                     /old_locus_tag="Afu1g17750"
     CDS             join(38972..39352,39455..40129)
                     /codon_start=1
                     /locus_tag="AFUA_1G17750"
                     /note="encoded by transcript AFUA_1G17750A; similar to
                     PIR:S50370: probable membrane protein YLR285w (GI:596038)
                     [Saccharomyces cerevisiae] PMID: 12736687; GO_component:
                     GO:0005737 - cytoplasm; GO_function: GO:0008112 -
                     nicotinamide N-methyltransferase activity; GO_process:
                     GO:0000183 - chromatin silencing at rDNA; GO_process:
                     GO:0006769 - nicotinamide metabolic process"
                     /old_locus_tag="Afu1g17750"
                     /product="nicotinamide N-methyltransferase, putative"
                     /protein_id="EAL91104.2"
                     /transl_table=1
                     /translation="MPMILQKKCIFHLVYRVQHNTTTWNTSKGASPPSGKGSEGVPWRW
                     IKMLHLRIRPLPRLQPASSIPTQSAPPSDFHNEDNSNDDDSAEDLFSAFLPHLFPDDAP
                     SFHGDPGQRLLYTSPRYGDLEIMLFAHFLWSAAMVVAEGVEKADTLATRGELDADTAMW
                     MVRGERVLELGAGTALPSIICARAHAAAVTITDHPSSPALTGAIDFNIRRNLAATEAEV
                     MSQPHEWGMLEPDPWAVAHRGAFTRIIAADCYWVRSQHENLVRSMNWFLAPGGKIWVVA
                     GFHTGRAIVAWFFETAMQNGLEIERIYERDLIATSEDGGEVRREWMPEREGEGPENRRR
                     WCVVALLQRRE"
     PFAM_domain     39461..39916
                     /aSDomain="Methyltransf_16"
                     /aSTool="clusterhmmer"
                     /database="35.0"
                     /db_xref="PF10294.12"
                     /description="Lysine methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_AFUA_1G17750_0168"
                     /evalue="3.10E-11"
                     /label="AFUA_1G17750"
                     /locus_tag="AFUA_1G17750"
                     /protein_end="281"
                     /protein_start="129"
                     /score="43.4"
                     /tool="antismash"
                     /translation="AHFLWSAAMVVAEGVEKADTLATRGELDADTAMWMVRGERVLELG
                     AGTALPSIICARAHAAAVTITDHPSSPALTGAIDFNIRRNLAATEAEVMSQPHEWGMLE
                     PDPWAVAHRGAFTRIIAADCYWVRSQHENLVRSMNWFLAPGGKIWVVA"
     repeat_region   42936..42969
                     /rpt_type=tandem
                     /rpt_unit_seq="tcattcatat"
                     /satellite="microsatellite"
     repeat_region   45381..45687
                     /rpt_type=tandem
                     /rpt_unit_seq="cagcg"
                     /satellite="microsatellite"
     repeat_region   45382..45718
                     /rpt_type=tandem
                     /rpt_unit_seq="caggcggcgcaggggaac"
                     /satellite="microsatellite"
     repeat_region   45417..45717
                     /rpt_type=tandem
                     /rpt_unit_seq="ccaggcggcgcagcggaaccaggccgcgcaggggag"
                     /satellite="microsatellite"
     repeat_region   46593..46683
                     /rpt_type=tandem
                     /rpt_unit_seq="ttaggg"
                     /satellite="microsatellite"
ORIGIN
        1 aatagaagta gtaggaagat gggaagctag ctatctaagc ataaatacta taaagtttat
       61 ttaataaggc tcttagcctt ctggtagcgt ctccacttaa ctagtactaa taattatact
      121 aatagattta atagaaacac ccaaaacatt gtattgttaa ttatagatag ataatagata
      181 ggatatatat actagctatg gaaccactat taagaacttc tccctatgcc ttagtaagct
      241 atatttacag tgtttacacc ctgttctata atagtaccta tattatatat atatatagaa
      301 gtaagcgtta ggatttagta tagcacttaa ttattaaata ataattaact aataagtctg
      361 cctagtaact aatagagagc tctagcctaa tatcagaaga attattatag attttagaaa
      421 tagtataatc taaagttaag taattaatat ataaagtagg agtagtaaat cagtttaaag
      481 agatagccta gtctatcctt aattcagatt agccaaaaaa ataaataaaa aatattttta
      541 aaagccttat agtatcttac tatctttatc caaggttctt tttgcattat tccttaagtt
      601 tatatagcac cttcttatat tctgcctgtt tatctgcagt agaagtatta aataatatag
      661 tagtaagctt tccatagata gtattcttct taacctagtc ttttaatact ggactcttag
      721 cttacaagtt aacttataag actatattaa gttattttat atttatatta taatatccag
      781 cattaatgca tagctggaat ttgctatctt tagttctaga taggattagg taactgcctt
      841 ctacagtagt gttagtaaat ttagataggg cattcttaat agcctatact ttttaaatga
      901 aagatcctaa gacttttaat atacttaaac ttattggatc tttaaataaa ataactaata
      961 ggatcttaga ggatacatgg gacttagtaa aaaagcttta ggatcttata aatatagata
     1021 gagtcctacc taccttaaag ctctgataca cctttatata aagctatacc ccataattat
     1081 taattaaact aataaatttc taaggactgt cttagtagat aataaggagt aatatatctc
     1141 agccttatta cttataactc taagtaaact catagggatt gcctttgttt agctgttatt
     1201 actcttaata tatactattt agatatcaga ctgggggtat ataattaaaa acagaaggtc
     1261 ataaccttct agcactctaa tttattggtt tgctctcttg attctcatag catgactgga
     1321 catgcaatca tctgcatatt gagtcccaac tttctgacgc tggatttatt ttccttgcgg
     1381 accactaccc agccagtaag taagcaagac tgtgtgtaca tagcacacta gctgaccaga
     1441 gactagacac attgtttatc cacaagtctt ttaaaggaat taaaggctat tacttgtctt
     1501 aagcacgccc agctatctac tactaatacc atcatctttt tccagattgc taagagaatc
     1561 tctcttatag ttaatactat attatattaa taagcatgtc ttacacagag atattagaag
     1621 gagagcttag caagggaatc taacaaaaac ttaaataact tcttacctat aagcaattta
     1681 aggggatact agagggttaa cttatatgta ttaccataca tttacagaaa cctatatata
     1741 tctagaactc cagaaatatt aagttaggaa tacttaaaac tttcatcctg ctaattaata
     1801 ataaatttat tagggaaggg atgatcactg tgtctctatc tagcttttaa ggatccttaa
     1861 cctttatagg tttaattact gagcttttta agagcttagt aaaggctagg acttttaaac
     1921 agtcctagga ctctctcaaa gagcttaata aaaataaata gtcctaggac tctcttaaaa
     1981 agtttgataa acagtcccag ggctctctca gagagtttgc taaataataa tattactact
     2041 tttaatatta aagcagacat agtcctattt ctagtatacc aacttagata agattattgc
     2101 cttcttttcc ctatagaggt tccctctgtc tatattaatt tatcataaac acctcatttt
     2161 caagagaact ggtgaggtgc tagaatataa tttagataag agttactaag tttataccta
     2221 gatagtcctg ctatagctgc aggaaggaac tactaatagg cctagtctat tatctataag
     2281 tcttatccta attacttata tatacataag taagattatg gatggtgatt aaatataagg
     2341 gcctctatgc aaggactagt taccactagc acctaatatt tatagtggca ttagtacttt
     2401 attatagcta aagggagagg gtagtttacc ttaaagtacc ttagagagag cctcatctaa
     2461 ctactgtagc tagatggaag atactctatt cttagctaag ggctgtagga atttatattt
     2521 atataatcat actatctata gcatgtaatc tatattatat taaatacaag atataggata
     2581 cactagcagg gcagagagag atataatacc ctaatagagc ctaagcccct gcatgacttc
     2641 cctatttata gcttattata tatatattat tttaatacac tatataatca taagcaatag
     2701 tagcctagta cactctttac ctctaaccta ttgtcacacc ctgggatccg tctctgctgt
     2761 tctctgctag tctactactt tgggaacggg gcaatatagt tcctggacta tatccggtac
     2821 ttgcctgagg cctatcaacc agatagcctg ataacacagt gatacgatga cccaaccgag
     2881 ggtcaaagac aactaaaggt aacataagaa caataacagt agagatagaa gcaaggccta
     2941 ttaagtatat atactcaata gtatagagta gctgacaaat cagactagtg atcttgtact
     3001 caagtgaata attaatatta aacgcgagga actaaaacta agagtgctag atacaacgtg
     3061 aacgagcgtc cttatatccc atagttcctc caggtggtag tggtgataga tggtatattg
     3121 gtaggatggt agatgattgc gataccctcc tatcattgat ctcatatacc catctaccac
     3181 atcacgtgat gatggttcgt agagaaacac attcagtaag taactactga accgtatttc
     3241 tgcgggaacc tgtctggatt aagtatttct ctggatcgtg ccctgatcac tccgggattg
     3301 actggtgatc attgatcttc aggtttctgc ctgttacatc cgcctagcac tagcgcggct
     3361 gtgctagtgt cataacatca cctccccctc tcctagtgtt ttgtccttga aacttaattc
     3421 aaaaggcagt gctcccccag gtgagtgatg tcctttttct ttgactatgt tcgcctatca
     3481 tgcctaagca tcgtgctgac actgtccttg aaggtgttct aaaacttcct tgtaaccatg
     3541 accaagtagc tggtcatgtc catcagtcag agtatattat tgagaacggc tttatcacct
     3601 tgtttccttg tgatcattat gcttcttctg gcaaggtctg cgtgatggat cgaacctgtt
     3661 aatattctaa atgcgcgtcg tgcacctatc agggtcgttt gtgcaaaaag gatttctata
     3721 ccaaaaagaa gtgggatttg cttaaaaggg ctgaaaagaa aattgcttcc gaactttccg
     3781 cgactaataa taaattagaa ctcttgtatc ctaaacttcg acagctgcaa gagcacttag
     3841 agaagattca gaaagagttg atagaaaaat aatagaaagt tgccaagtcg ctggcccgac
     3901 attcccgtct ttataaataa cagaaattcc tcaaggagcg tggtttcaaa atgtctgaac
     3961 ataatgctga gttgttatgg atcttggatg agaagaagtc atctgatcag cctaatccta
     4021 ctgctgaggc ccaacagtta gctatgactt ctaataatcc taattttaat cagataatag
     4081 cagagattga tcagatgccc ccctccttct gggagaactt tgatttccct ttaaacagta
     4141 ttgttgaacg agttggtggc agcccgtcag attcttaata ggctcccatg tattttctga
     4201 ggtattataa cctttccact tcacaaggta gtatggtttt ctactgactt acttgtgatc
     4261 cagaatttgt ttaactttat attcctattc tatgtcgtcc ttaatttcta tattttcagc
     4321 aatctttgcg ttttctggtg ctggttctaa taataagaca tgaaatacta ggtgaatctt
     4381 taacatgctt tttggtagtt gtagtttata gttaactagt cctaattttt ctgcaatgac
     4441 aaatagtcta attttctgat ggtccagttt ctaacttagt ctttttgttt taatgtttct
     4501 gcagagcagg taaactttct cccccctttt caagtctaga gcactcccgt gcttctaatt
     4561 atagtaaatt accatgcgga ggtttatgaa ttcgatgtcc ttcgaaagtt aagtccttaa
     4621 ataattaata gtatccacca tttctgcggc ttcttctgct gtgggtactt tgttttgtag
     4681 ttctctaatt aacatagggt tgtatctgta attagcaaag aaaggtattt cccctgtagt
     4741 tgaatgaata gcattattgt atgtgaattg tgctattagt aagtaaacta cccaatcatc
     4801 ttgctagtaa ttcacatagt gttgtaaata ttattcaatt atttggtttg tttatttagt
     4861 ttgtccatta gcttgtggat gatatacggt cgtgagtctt tgcttaattc ccattaaatc
     4921 tgttaatgat tgccaaaact ttaacatgaa taacttatct ctatctaatg taatgtatcg
     4981 tggcattcca taattcacga tcacgtgccc tatgagtagg ctcgcgagtt gtgatgctgt
     5041 tatctttgtc attgttggaa tcaaatggat gaatttcgtg agtctgtcag tgactgtcat
     5101 taggtaattg taccctttta actctagtag tagtccgaca aagtcaatgg tgatccattc
     5161 ctatggttgt ttcggtgctt ctggtgattg cattttacta taaggctagt gtctagtggg
     5221 tttgtctcta atgcaagttt tatactagtg aatatatcct tataccttcc ttctcatgtt
     5281 tgggaaataa taatttcttg agatggcttc ggctgttttt ttagttccca tatatccata
     5341 cattaggtcg tcatggtact tcgcgatgat cttggttctc atacactcgg gtatgtagat
     5401 aagtccttgg aaatatatta ttcctctgtc gtctgtaatg aggtgtttgt tatccactga
     5461 gtttttaagt gtttcttaaa taattttatc ctttttggtt gctttaataa ttctttggat
     5521 gagtgggtcc tcctgtaact taattatggc tgtgagagtc tagtaattat atgtcagtga
     5581 cccatcctcc tgttgtttta atatggctag tttaattatt ttcccttgaa gctcgtaatc
     5641 cagttattga ctaagtatgt tggcttgtct attttccgtt cctttgcagt gaacaatctt
     5701 aaagtcatac tgtgagagtg tctcagccta tctggcttgt ctccttgtta gttcttttgt
     5761 ggtcgtaaag aacgtgaggt tcttatgatc tgttttcaca ataactgttt actatgctcc
     5821 ttctaggtag accctccaga ctttgaatgc taccactata gctagtagtt ctttgtcatg
     5881 gatgtcatag ttaagttccg cttaaatcag ctttcttaaa tggaatatga ctagtcgcgg
     5941 tcttccatca gatcctggtt gagttatcct tattctgatt gcgtagtcag acgcgtcggt
     6001 ttcgatggtt gtttctttgt ccaggttgtg ttgcactagg attggtgctg ttataatttt
     6061 ttctttaatc ctagtgaatg ctgtttcgca ttctttagtc cacttaaact ctttcccctt
     6121 cttgagtagt tcgaaaagtg gtgtcatgat ttttacgtat cctttaataa attattaata
     6181 atagttcaca agcccaatga attgctgggt ttctttaacg tttcttggtt gaggctattc
     6241 tcttatggtt ataactttgt tttagtccat atagatgcct ttagtagata tccagtgtcc
     6301 taagaacttg gtctcttaga catagaattc atacttcttg agtttcagtc tgatgttcgc
     6361 tttctgaagt tcttgtagaa cctccttaac atattccaca tgttcatttt tattttctaa
     6421 aaagattaag atatcatcta gatagactac cacaaagcag tgcagaacct tgtgtagtac
     6481 ttcctcaatg aacctttcaa acaatgctag tgtgttggtt aatctaaatg gcataaccag
     6541 gtatttaaaa tgtctgaact ttgttctgaa agctatcttc tattcttcgc cttctgcgat
     6601 tcgaatgtga ttgtacgcat ccataatgtc taactttgtg aaccatttcg ctcctcgaat
     6661 tcaatcttag atgttgtgga tcaacggaag tagataataa tccttaatta tgatcacatt
     6721 taatagtctg tagtccacac agagtcatag acttctatcc ttttttagta taaatagtac
     6781 accatgtcct gccggtaagt ttgatggtcg tatcttccca agttgtagtt attcatcaat
     6841 atattcctta agcgcttgta gctcttttcc tgatatttag tatatcttct tatatactag
     6901 tgactttcct tcctgtaaag gaatccagtg gttatatttg ccatgttcta gtagaacata
     6961 ttgtttaggt tgttcaaaca atttcttgaa atcactatat tcctaaggaa gaatcagttc
     7021 caaccctaat tcattcctag attcagtgtt cctaggactg atcactctag gatcatccta
     7081 gtcctgattt attattgccg agaataagta gggttctggg tcaaggatat tcctgggact
     7141 gcctgtcctg ggattaattg tttctctgta tttcatttcc cagatacctt catcatcact
     7201 ttctggtgtt atgatattgg tgtaatcact atcttactct ggtgcccatc ccagtagctc
     7261 catcattatg atcctttata atggtttggt tgctgctaac actgctatta tcctctagct
     7321 agttattact tctttcttca gtccaccctt tgactgctta gcatcatcat cgctatcctt
     7381 taattataca tgccataagg tcctaatttc ccctttattt cagtcctgtc atgggcattt
     7441 atagttaaac tagatttgat ttgtgttcta gttaatcgct aggttatgat tcctgagcta
     7501 tagaatccct aataccatat catactgtcc tatcagcaca atatcaaagt ttagacattt
     7561 aatatatcct aacacaacca ttaggactgg tcctgattca gtcatgattg agagagttcc
     7621 taaattctct ctatttagat ctgtgattgg ttcaggtact gcctttattt ttcctaggat
     7681 ccctagcttt cttataaagg ctaggttcat aaagttgcct attgctcctg agttaatcat
     7741 tacttcagct aattagttaa gaatgtttgc aactatcttt aagtacttcc tatgctgcac
     7801 tgtcgctgcg aggtactcta tttcctattt tagtgcccta gtcattagta gtagcatggg
     7861 gaaatatcct ccaactaatt tgccttagta gtgtactgtg tattagtctt taaagcatac
     7921 tgtctaatac attgcattat gttctaagta ttacctatat cctctgtaag agcattcaag
     7981 cttctagcat agacaagtgt tattctcctt cataattgcc agtacctcta gctaaaattt
     8041 tgccatgtat ttgttattat ggtagatgct ataattatta ctgtaataag taatccatag
     8101 tacttattca tgtcgtgggt gtccttggaa atgtttgcat agacactagt tgtaactaca
     8161 tttcctataa aatagtccta gtagtctctt ttccaatacc cttttgagtt tattatgata
     8221 ttctttgttc cactgcctgc agtgttagca atatactata tgctttctgc agtgtgttat
     8281 atactattcc caagattcaa ctcaggtcca atattccaag ttctgatgtg tgcatccttt
     8341 taccccttgt tcaaccttct taagggttca cttatttagt tagtgcgctt ccagttctac
     8401 caactgtttc ctatctagct atcatagcca tgtggcatat cagtctactt tatcgtcgtc
     8461 ttgtagggat ttatttctag gtgtcttagg aatcttgtgg ggctgctcct tgttgggatt
     8521 aaggcccact cactaagttc tgtactcttc gtcaagtgga ttaataggtt agttaatagt
     8581 agtccaatct attacgggaa aatcctcttg agctggctta ttatagttag tattttccaa
     8641 gtcaggacca ataacctgac atatctcata ggttaatgtc gtctattagt gaataagccc
     8701 tccaggtgta atattctcct aattaataag gctgtctgca tcgctgttag gtgacttctg
     8761 attagtagct ataaggatat ttaagtcttt agcagactaa tcatccttta cgcttttata
     8821 gtcggtggag tcttctttct caagctctat ttcgatttct ttgtcactca agttcgtaca
     8881 ttccttgtac aactttctga gttattcatt acttttcttt atcttaatag tgccagtggt
     8941 gtcatatctg tttcttctaa tcatagcact aagctccttc gtggcttgta tctatttctt
     9001 ctcttactgc ttacccttcc ctaggttttt cttgcagttc ttggatatat gtcctagctt
     9061 cccacaccag aaacatagtt tctctttatg tcgctgttct ctttccttat tggaaagtgc
     9121 cgtgtgtgtt gcatctaact ctattagtta tagcccataa ggatctaagt atccttagtt
     9181 ccgcggttga gcgggtctcc tattgtttgc ttgatagttc atggtttatt aattgctgaa
     9241 gctattccag ctgcttcatt cacatcttta tatatagaag tcttgtaact tattgttaat
     9301 cttaactact tgtttaatta tcttgctaag tttgtctagt tattccatcc agattaactt
     9361 ctcctagatc tctggcttca aaccttcttc aaatcttgca atgttcatgt ctttgtccta
     9421 attcagatgg gatataatct attagaattt taatacgtat tcctctacag atcctgtttg
     9481 cttgagttgc tatagttatt acttagcgtt cctttcttta ttaatgtcgc cgaaagtgct
     9541 ttctaatcat ttcttgaaag cattatagct ggcgaatatc tcgtcagttt tgttagcttg
     9601 gttatcctct ttgtactctt aatagtctct gataaagggt ttaaactaat taaatactgg
     9661 tctagttaga taggttgctg taagcaagac cctttctacc tcagtgatga gtttttccct
     9721 attcatatag atatacatgt ctaattatat aagaaatact cgtaacttag acctgtttct
     9781 attgaacagt ttaggtagtc taactttgac agacttagct gtaagtcaac cttctagtca
     9841 ctagatatat tcctgaagct acttaactat accttttagc tcttctgtta aaggctatag
     9901 ctgttattac tgtgtagtag gtgcccaact aatattagag ctagtgggga tctgtggcgc
     9961 acttcctgct ataatattta atgttaagag tcaattaaac ttcctaaagc gattcgtact
    10021 gtatggtatt taatttgtta caccctggga tctgtctctg ctattctctg ctagtctact
    10081 actttgggaa cagggcgata tagttcctag actatatcta gtacttacct aaggcctatc
    10141 aactagatag cctgataaca tagtgatacg atgacctaac tgagggttaa agataactaa
    10201 aggtaacaca agaataataa cagtagagat agaagcaagg cctattaagt acatatactt
    10261 aatagtatag agtagctgac gaatcagact agtgatcttg tacttaagtg aataattaat
    10321 attaaacatg aggaactaaa actaagagtg ctagatacaa cgtgaatgag cgtccttata
    10381 tcccatagtt cctccaggtg gtagtggtga tagatggtat attggtagga tggtagatga
    10441 ttgtgatacc ctcctatcat taatcttgta tacccatcta ccacatcatg tgataatggt
    10501 ttgtagagaa acacattcag taagcaacta ctgaactgta tttctgcggg aacccgtcca
    10561 gattaagcat ttctccagat catgccctga tcactccggg attgactagt gatcattgat
    10621 cttcgggttt ctgcctgtca catccgccta gcactagcgc ggctgtgctg gtgtcgtaac
    10681 acctatctaa aaaaatgtga ttagacagta gtatagatac tctcttttat cctaaataag
    10741 gaaataatat aaggtgcagg aaaaagactg taaaggatat aattaatata gttatttaga
    10801 ctttcttcct agatttaaat tattaaacta ctaaagcaaa tattactatt cttcctatct
    10861 tctaattaca cctatagaat tactttatct ttaagtctgt ctattcaggc ggtctcttat
    10921 acctcttatc taactctttc ttattaaatt cttatataag ttacccttat agaacactag
    10981 agataattta caatatagtc actaatagct cttctactct agtctaagga tctactaaga
    11041 gatcttccta tgaaaataac ttcactaatt agggaaatac agtaagaagg cttctaaatc
    11101 cttactatat atctaattca gtattagcta attaatatta tattccttat tatctctaga
    11161 ttcctttata acataaagga ttctaggatt tattatatat ctccttaggt taataaccta
    11221 cctaattacc ttctaactat ctagctaagt actacagagt cttagttaat aatataggta
    11281 agtaaaagat cactcttaag gtcctgcctg actataatcc ttagcagata atagctctat
    11341 acagacagat atttagacac ctccactaaa ttaactacta tagtattagt taagtttagg
    11401 ttagatttat taaccctaat aaataatata agcatcccta taatgggcgt gaaaagacaa
    11461 aactaaactg gtggctagat ggtgtcccac acacatcact atattatctt aggacagaca
    11521 gtgagtaatt aatacatatc tgctagctaa ctaagctaat tattaataga ttaggtcact
    11581 ctcttagtct atattctcca tatatctagg aaagggaaaa ctataattaa taagttgcag
    11641 aaggctgcag cttataagat tctagtagat aaataagaga tcctagacaa gattattata
    11701 atctaaaggg gtaaagagga ggtagaaaag caatataatt atagtgtata tcaagtctaa
    11761 ggatccctat agatatacta aatttttcag atgatattaa ggctactgag accatagata
    11821 aagagctaaa ttaagaactt atctaagtct ccagcttagt aagtaataga ggataaggaa
    11881 gatctcctgc aggaagctta gaagactaaa ctaaagagat ctctctaact agtcctttag
    11941 cagaatcctt attagctagc tcctatcttt taatatctaa aatactagct aacctaattt
    12001 actatagttg aagcccagaa ggctaaatta aaaagatcta tctgtctaat ccttttatag
    12061 agtctttata gaactttaca cctaccacct atgcttctat ctcagaagct ctggctgatg
    12121 aaatatagaa ttatagaagc cagtattaaa taccacaccc aatagcttaa tcaataagct
    12181 atagagccct gttcaggtaa gtctgctctt ctcaccctta aagctattat gctaattatc
    12241 ttccacctca tgagcagcaa ctatgccttg gccgtctatc atggccatac cctaacaatc
    12301 aatcttctaa acacacaatg cactgctact aattaatgca gcctatataa atagcatgct
    12361 actcctgcta ctcctgctac tagtgtctca tgacttaata taatagctct aacctagtct
    12421 attctatagc actaagtcta agttcatcct agtagatgct tccatcaaat ttaatatctt
    12481 atttatatac cacttcctac agttttcctt actaatcata gctaattaag aataataata
    12541 ataataataa ctagaacact ttgtagtatt agaattatta atgccttcta taaaagcacc
    12601 ctggtattat atagtgcatg ttttagtttt taatcttatt tcttttatct aatagttaaa
    12661 gctctagtta ttaagtactt ttattagctg tatcctagga ggcacacttt atctagagca
    12721 acccttggaa ttttacttac tatatatact gcctagaagc actacatgct aatttataag
    12781 taattaagcc tttcttaagc tatagataat tatattacta ggattattat actagtaatc
    12841 ctcccacctt gtaagagtat tatgtttata tattatttat tatatactca gtatatatta
    12901 ccttcttcta attctagcta atttaggctt gctacttgct ctaattatac ctacttctac
    12961 ttttatagaa ttcttcctaa atatagagtc ttatatttag gcagcgtgaa tttagaaaag
    13021 acttcactac ttagaaccag gtttttagga acatacacta gccctaagta atataaatat
    13081 atgtagagga gaaggaacag atatataatt agctatatgc actactctaa tttatactag
    13141 tgtaggatga agcctataaa taccactaaa tattaagagg aagtatcttt gaaaattaag
    13201 aagaataaat actatagagc ctaaagtctt taaagcaagc taacctatgt ttttagagaa
    13261 tcctatatca acccagatga attgctgaag taaatagcta aaaaatatag aagggggaac
    13321 ttctatatta aggtaggtat taataaatat aaatatataa agtaatagat aaatagcaac
    13381 agttacaatg cggtatttat agtatttacc ttttaaaaga ggttaaggac taggagttta
    13441 taaagatagg tatacaatag catatttcta ctacttacta atagctaagt aaaaggatta
    13501 gtacttactt atagttagta tattataagt ccactaaaga gaacaaacct acctatacct
    13561 agatactttt agcttatcct tttcttgtaa agcatacttt ataaagttaa tagagtttaa
    13621 aactattctt acaagacaga tctctaaggg aatctagagg attagatttc gcaacgtgat
    13681 atacagataa atgaactatt tacttaaagg atttgctagc tcttatttaa tatccttcct
    13741 aattacaagg ctttatctta agtacttaat ctatgtgtat cctagattat agtaatccta
    13801 ctatatccca gccatcttag ttagatcttt ttttttaatt tcattcaatc ttctagtaga
    13861 tggtgttcat ggattaatac cataggttct aaatcaaagt acttagtaat tttaaattat
    13921 aggaaggatc tattttcaga tcttataggc agctctatta taatttctag gctctgtctt
    13981 acagtctaag tttaatcagg aattcagata tagatatatt agtactttag gggagcctaa
    14041 gctaagctct aggttatgag taataaagtt aacacaccta gcatacttag aggtaagtag
    14101 ctcttattaa gcacctgtat tagaaggagg agttaagata gctattagct agtataatat
    14161 aggttaatac actagctaaa gcagagtaaa taaagtcctt gtagctttct actattacta
    14221 ttctacttta acttactagt atagaaagtt agctagccgc cagtgtggag agtatgatat
    14281 atactagaag gcggtgaact aataactttt atatttattt agagtatata gtctggcatt
    14341 atagcagata gattagttat taattagcct taactaagat tagatcttat tactagacaa
    14401 ccacactgaa taataactat ttcctactaa tgtgtttcct actgaaagta gaagctatag
    14461 ttttaacaag ctattataaa ctatagctaa ggacatttat taactacttc tagtgcctag
    14521 gactaagcgg cttaattata gcactaggga aatatagcct ctaagttact agttataaaa
    14581 ggtggatgaa caggtagttt taatcctaga tgtttaatac tcttaatttt agtattatag
    14641 aaataatagt attatagcat aatactagta tatatctttt cctctgtact ctttgcccta
    14701 caggcactat taataaatat taagtttgtc tcctattata agctaagact tctttcttat
    14761 atttatcttt agctttaata acaaggtcac agttaaactt agtgaaatag aaaattaagt
    14821 agtgtactat gttttagttg gttctaataa tatactaatg tttttattaa acagactaaa
    14881 aataaatatt agtgatcaag ttcagattct aaaatgtgaa ccatacctta acctagttaa
    14941 gccttataga gtttgttctt ctattagaga atttaatact agatttaatt aatataatcc
    15001 taaggataag aacagcctta ttataactct aactattaag tctcttaatc tataatagtt
    15061 cttttgcaaa tagagccaac tattatctta ttattatact agtatagtct ttgtgcttaa
    15121 tctaggtaat agaatagatg cttttttcta aaatatatag aggagcacca gtgacctaat
    15181 tcctagccta gtgtctactc tagttccagg gtatgttgca ggatccttga gcccattcct
    15241 tgctgtttct agttctctta ctacttctac tacttctact acttctacta cttctactac
    15301 ttctactgct tctactgctt ctactgcttc tactaatact tctactactg tcttaatatc
    15361 ttctactact tctatttctt cttcagttcc ccacccttgc tctaaggata tacttgcctt
    15421 aagttctacg caccttcctt taattataag cccagtgagg gttataacta taactaaaat
    15481 ggttagttat actagaatgg ctgactaatt atctattaga tatttaatct taacatctga
    15541 ttctacttta gagggaaatt agttaatagc agctcccctt agtgcaagct tattcactcc
    15601 ctttactatg atagtgttat tatagatcat tataaaactt ccttactact tacgctggta
    15661 tgtttatttt tattatttta ttttactaga cctgcctata gtatagacct ttattccctt
    15721 ccttatatct tctattacta catactataa gatttatagg atataatgat atagttgcag
    15781 acaggtaata aataaagata gttatttcat tctcccttag gacgacatta tttcctagaa
    15841 atgtatttct taataaatgc tactactagg ttattcttta agaccacccc ttatctctgt
    15901 catagaccct tattattaac tatataacta gagatattca ctttgctgcc tgaagctgtg
    15961 tactttcttt tatgctaaac tagttctaaa ataaataatt aatatacctg ccattgcttt
    16021 catgcagtta gacctactta agtaggtggt ttaggattct aaatataagt aaaccatcaa
    16081 attccagctg ctgataggga gtatagaata agatcttaaa aaagtcaagt taaaattctg
    16141 cctgttgata agtaactata tattataagt ttctctaaca gaagtctata tatatgtcat
    16201 aaaataatat tatgtacttt agcctggtgg agtttatact taggaagact gtataaaatt
    16261 atattataac taggatagtt atattttcag ctatctagaa actcatgcta tagcttatag
    16321 gtcacaaagt acctctacag tgtatctttg caagcatata tatacttttt agccctagga
    16381 taaatattaa tgtgaccaag acatataggg catttaagtc tagtctcact ctttggcgaa
    16441 gcaggatttt tagtgattat attaattaaa ggtctattaa agcagactct tctctgcagt
    16501 gctcttggta tattaagatt ataaagagcc aggtataact ctagggaata gatccagtcc
    16561 tctataagtt ctgcattgtt aatcttgtct atatctctat tcttaaactt aaggtctata
    16621 agagcctttc tctctggcac aatataggag atgtctggct taaaacttat caggttaccc
    16681 tggtaatttt acttaataat ataattacta atattcttaa aaaactctat atactcctag
    16741 ttcttagcag ccctatacag tttctttctt tccaatctaa ctttattact agctctttaa
    16801 aactccctgt atagatctat gccgcgacta ttatataact agtagtatag tgcgattaac
    16861 tcagcctgaa ttatgttgtg cttgcccttt agactaataa gcaccaggtc cttcttaagc
    16921 tcttgctttt actgattact gagatcttat agtgtggaca tgttatatat taaacttaaa
    16981 ttagtcatga gcttaattaa agcatcccat gcaggagtct ctataaaggc taattaggta
    17041 ttatcctaga cctgtatata gtaggcaaag gtatttgtca caccctggga tccgtctctg
    17101 ctgttctctg ctagtctact actttgggaa cggggtgata tagtccctag actatatctg
    17161 atacttgcct gaggcctatt gactagatag cctgataaca cagtgatata atgacctaac
    17221 taagggtcaa agataactaa aggtaacata agaacaataa tagtagagat agaagtaagg
    17281 cctattaagt atgtatactt aatagtacag agtagctgac gaatcagact agtgatcttg
    17341 tacttaagtg aataattaat attaaatata agaaactaaa ctaagagttc tagatacagt
    17401 gtgaataaat atccttatat cccatagttc ctccagttag tatatccggt ggtatatcct
    17461 gggtatggta gtggtatatt atatacctta ataatgttgt cttggcatac catctatata
    17521 ttgtttatca tgtaaggtgc tccttattag tatgctttat tatataagta ttaatattca
    17581 gtaagcaact actaaactgt atttctatgg gaacctatct agattaagta tttctctaga
    17641 ttatgcccta atcactctgg gattgactgg tgatcattga tctttaggtt tctgcctgtc
    17701 acatccgcct tgtgctagcg cggctgtgtc agtgccgtaa cagtattact tctcttataa
    17761 cctataataa tattatagga gtgtttatta agatgtcctg tagacctgtt aactctagaa
    17821 actaatagta gataagaggt atatattact taatttactt acagctcctt tctaatattt
    17881 ataaagagac ctaggactct taaaacctgc taacctacta gtggtaatct tatattccta
    17941 tgcttaatca tactgcaatg ctagcatgag ataagtaatc tagtatccct tagaatcctt
    18001 tatagcatag cagaatatca gaatttcctt cacactctaa agtagatagg ggtgctgagt
    18061 taatagttag gaatataggt atagagctag atatctcaag gccttttaat atactaactg
    18121 gcaaaagtat tattaagaat agcatattct agtatgtcct agataacata aaggctaaga
    18181 ttattattct acttagtata tgtgaagaca ggtctttaaa aggttagtaa gttttaagca
    18241 gggtaagaac taaaacttat ataataccct tatttctctt actcttattt aacctatacc
    18301 tgacttacat gagaagcatc taataattta aatcttctag gtgcttcact atatagagtt
    18361 taatatcttt ccactttagt gtgttggggc ttcttatata cctagaagat aagataagca
    18421 ttctaggaca ggcagatatt aaagtcatca tctttcacag tgtgctaagc tattattaat
    18481 atcatactat agtaaatcac actttacaga aagccataag ataataagta ctatagagga
    18541 gatccttaat attcactggc ggctgagtct ttgctcctaa attaagctta tacttattag
    18601 taagtatagt gcatataagc tactaatatc agcttgatcc ttatctctta aatattcact
    18661 tactattcat cttacgcctt aacatataag gaaagagact atctatttct tagtactaaa
    18721 agactctcta atatcatata aaaactaaaa atcctaacta atacttaata ttataattat
    18781 taagatatca gtaaagaaat cctttaatta ctcttaaggt gatattcctt agctagtaaa
    18841 catagtctag tagttaaagt tctaatataa atctaggaat ctaaattagt aagagctata
    18901 tctttattag cagtaaatta cttctgaaaa ttttacttta taagatagat atagttctta
    18961 gtagttttag taagattatt cttaaccttt agcttagatt gctaaacaaa gctattctag
    19021 ttaatattag ccttctttat tttgctttaa gctattagaa ctaaataaga ctataagtag
    19081 tttaattaag attaaataat aagaaattag agtctctaag catattaagg aatgacatct
    19141 taagaatgaa gaggaaagcc tattataatt tttttccctt atccttaata gtctgcttct
    19201 acttattaaa attatagtat atgcactagg cttatcttat aaggaatata tataaactgc
    19261 gctaagacaa aataaggaat agttaactag gtcttattaa gtggtgattt atagtatgga
    19321 aaggccacag tttctagcgg aaaagccatg cataatcatg tcctttccat cgtcacccag
    19381 acttactccg tagtaattga gaccccactc tgcctgatcg attcgctagt gagaatctta
    19441 cttcgggccg cagtcttatt gtacaactaa acggcccttc tacctacata atgtcctccg
    19501 tagcttcagg gttgcacatt ggggcgacca cgccaactca atgtaagtgc ccatctcaat
    19561 gtctaaggat atgcacccgg acaccctttt agccgaatgc tgtggctttg aaagtgtcag
    19621 agatactcct tacaatggta gtccttcggc agaggctggt ctcagttagt tgtattttcc
    19681 atatccctct ttgggtacga aactgagatg cagtatatca cataagtcta accaatggaa
    19741 gtactctgtg cgtcggattt ctatctaact gagctgcggc ttacagagag cttagcgcca
    19801 caagaatgag attgatagtg gatcatccag accggccaaa gagagcctcg agctgctcgg
    19861 acggggtcat cgggcaatgc cattgtttca ttggtctatt gctgcacctt gcgcatcgcc
    19921 tccaaacaat ccgaaacaat caagcttgcc taaggctctc cagctaggct tactttgcgt
    19981 atgttcgcac gcactgccac tgatatcaaa tactacatag tatagagaca tcatatagtg
    20041 tctgtatgga atcagcacta gagtatcaat attgattcgc cataagtata gttattaaat
    20101 tcttgtatag tacctaggga tactaatatg aagtttagtc tcggttcccg ctgctacagc
    20161 agactgcaga ctgtacctac aatgtggact aaaatttaaa attaaatata tgttaccact
    20221 ctcaccaccc cagttgcacg cactacctaa atagctaaat ataaatcatt atctaggatt
    20281 gaatattgaa ttattatctt ggatatgtca gtttagtata ttagttagtg ctttgtgaca
    20341 tgacgtacag ctagtgtcca gtttagagga ctttgcaggc gctgtatgat tcagttgcac
    20401 agcctaggca cttagcaggc cctgcccgct acaccatatg ctctgtagtt aggttttgaa
    20461 tttccatata gtaaaatatt agggattcaa aacctcatgt atcagagata tcaattattc
    20521 gaattgctat atagtaagga ttcaaatcac gttatagtat atacgaaggc caacatgcct
    20581 ctataggcag aataaatata tagagaagga cagaaggtta taggggaacc tgtccactat
    20641 aatgtttatt gagaataccg catttaatta cccctactat actccatatg atagttttta
    20701 tccctagttc cctactacat ggtaaaacaa atcattcgat atccttacta tcatacagcg
    20761 atttgaatcc cttctacatg gtgatttgaa tcattcgaat ccctattata tggtgatttg
    20821 atattgaata ccatggattt aatgtcctag atgatgattg aaaatatgtg gaagtagtgg
    20881 caataggaaa tacatgcacc gaacagtaaa aaacattaaa agcccacatt gcaattacag
    20941 tccacccgta caatgcttta ttgtggggca cccctaaggg atacttccta ctgtttcatg
    21001 cactcaacct gttttggaat caccactgca aacatcttag gtgaccatgt agatacatgg
    21061 aaacaccctt gttgagcact tggaaataca aggattagtc ttcttatcta gtgattacta
    21121 cttgatacta tttattgtgt catcctacta gtctttctgt cagctgctaa tcgacataat
    21181 cgtcacctaa gtcctaatta gtcaacaggc tcatctgatc taccctgtct cgtggatcct
    21241 ttaaaaaata gataccaagg tagtatttac tgtgctttgt atccttagta ttcataacta
    21301 agactgtttt tgtttgtctt gggccgggaa agggggatgg agaagcccat tactaaattg
    21361 gctatatatc tacatatatt gatattcata tcctactata taagttgaaa tcaacactat
    21421 gtgaccattt aatattgatg ccatatggca atttgatgtc aatactgtat ggcaattcga
    21481 tatatgatga tctggtatac caactacgta tatgagaatt taatatctga ggtagcttac
    21541 ccattctaat aaactagtac ccctctccca caggatctac cttgataggc tgaaaagttg
    21601 gttcgcggcg cagacaactt acatttccct ccacagctac atgttagtat gtaacgtact
    21661 agactaaatt caccaggtta atttctaaga ggtattcttt agaaagaatg attagacaag
    21721 agggcaggca tatttggttc acctaacagt aagaacatca aacagttcct agctcctttt
    21781 atgcaattag cccacaggga taataaaggt gtgtatggag tagtactctc aaaatagaaa
    21841 agcaaaggca ggaacagggt aacagcccgg gcctttgcgc cattctttat aagccaaatt
    21901 cccaggcact aagtttattt attgagcgga tactttattg ctgctaagaa gatgatgaat
    21961 agtgaacgaa agctccgtgc ggcatgcgac cgctgccatg aactcaagaa ccaatgcact
    22021 cgcactggtg ggcctgacag tcggtgtgac cggtgtaaga ggcttgatat agactgtgtg
    22081 tataacacca gtgcgcgcat gggccgcccg cgagtgtcgc ggccgggttc tgagaaccat
    22141 aaaggagcat cctccaccag acactcaaaa cgaggtgccg tccaggccgg cagccagtgc
    22201 ggtgctactg cagtgccgct tcctgttgat catgtcgatc tagcttcggc agtacacgat
    22261 agatctggcg gttctggatc agatagctcc cgcagtctcg aaccagtgct agggcttcta
    22321 gatcctgttc ccctctccca ggtaacgttc atacacccgc agaccctgca tgcaagaacc
    22381 gaaatgctaa agaatgtgat aagtgatacc tagtgacaat gcgatctagg acctagagct
    22441 gtattccccg gactttgcgc acccggctca cgatgatcca acaggcggac aggggctcgg
    22501 acgtggacat gggcacgccc accgggaata tcatcaagtg gagagcctac aacagaaata
    22561 caaggaagtg cctgacttct ctgaatccga cctggagatg tcagaaaagg gaacagcgcc
    22621 tattgttaag actaccggcg cagatgagct cctacggctg cagtttcacc taagcaatct
    22681 gttaacaggg gcgagagaat cgcccacaag gcatcagccg gccattgatg aggtcatgat
    22741 ggtctgcaaa gagctgctag agctgctccc catctcagct cattgctcct cttcagactg
    22801 cggtactaca agtaagagtg ggattggggc aggacggcca ttcactccag ccagcgtcaa
    22861 tgctgggcat cctgatccct gcgacggaat tggccagcca actcaacgag gaggagggcc
    22921 gttccaccca ctaaggataa actacattgc cttcctacaa gtcgcgacat catacgcata
    22981 cgccttgcag ctgctggatc ttgctgtgga taatctcata agccgtggtg gtaatctggc
    23041 cctcgtaagc ctgggtacct tcaatcttgc atcccagccg gccatgagta cctcggtggg
    23101 tgcttatatg atttcgagca tggtccatca gctgcgtgat gctattagtg tcttgactcc
    23161 tgaatatcag catcagcaaa ggccaccacc accgcatgca tcatcaccaa atggccttcg
    23221 ggcggccgct gcgactgcga acaattcgat acatgttgcg gtggatatga tttctcagaa
    23281 ggagacgtct ttactcgaca aattggcgca gataatgatt aaaccatagt tatgatttgg
    23341 ctttggaatg ttttaccata gggtgtaatg actttatact cccaataact aggttcagac
    23401 aggcttcgaa attctatttc tcgttatatt cttgtgtgat taagtaccat gaacaagtct
    23461 ctgaggccct tatatgccct ccattgtacg ccatttttac tgatgacttt ttcctgcctg
    23521 tggagaaatc aacagagcaa tctcacatcc ttcaacagta gaagtcgccg gtccagtaaa
    23581 tgccttgccc cagtaagccc ggaggttaag taaaacagca cacacggcgt cttattacag
    23641 gcactcttct tttagagttc aaaaggtaag ccaggctgaa cacacaatgc agtatccatc
    23701 acagctcacc aatctctaat ccattaacac caccaccagt aatacccaac aaaacacagg
    23761 ccagccacaa atgagcccag aaacgaaacc cgccatcatc tgccttcacg gccacggcag
    23821 caacggggag atcttccaag ctcagtccca aaatcttacg cgagtcctat ccccccgatt
    23881 ccgtttcgtc ttcctcgact cgcccatcac aacggcccaa actggcgtcg gcgtgccacc
    23941 ctactacgca cacataaagc cgtacagacg gtggcatcag gacagaaaca caatcgggct
    24001 atttgatgtc acagcggaag atgtcgagcg tgaacgccgg gctgtgcggg attcattgaa
    24061 ggatgttatt gagcgcgagc gccgaaatgg accaggggcc ggggttgtcg gcgttatggg
    24121 gtttagtcag ggaacgaggg ttgcgacggc cgtttgtctt gactctgagc tggggaggga
    24181 catcaggttt gcgattatga tttgtgggat ttgtccttca ctggcgttga gtgctgctga
    24241 gacgcaggta tcgcggccgc tggatattgt gcctgtccat gttcagggga gtggtgatcc
    24301 gtggttggcc aaggggacga ggttgtcgaa acagtatttt aatcaaaggc tcgcgacggt
    24361 ggtcaggttt aaagggaggc atgagattcc ggtgacgaca agcgatgtgc agaatattgc
    24421 tgaggttatg gcggagtatt gggaacagaa gcgtgacacc gtgctggctg tcgaggttgc
    24481 gagcgagttt gcggctagaa tggtatctgc ctagagagac tggtttataa attgtagttt
    24541 tatagacaca gttgcttcta tataacagta tgtttatata cagcaattat caggccgatg
    24601 gcttccgtgt tcatcttctt tcaactgaga acttatacgt tgcaaatcgc gtatagagtc
    24661 cgtccatacc ccaaatggtc tctctgtgtc tccactccgg atggtgcact gcatctggcc
    24721 agtcttgcat ctctagagat atcgctgcgt gttgagcgac tttgccttgc ccttgacctt
    24781 tcttcaaccg caacccagct gtagacaatg tcagttgcga ctccaaccac tacagaagaa
    24841 tgtcatgtta cccaagtcac tgttccacgt gtgaacatgg agagcgtcct ggtccgtgta
    24901 aagctccatg gtgacaccag atggcttcga ggagaggatt gccacaggtt cgtcttcctt
    24961 gtcgcccaac ggtttatggg agagcacgta agtcacatca gatccagcat tacccttctg
    25021 aacctcgtcg ccaataaact tatccgcaga ccaaaagtca aactccttcc cctccctatt
    25081 actcttcata tcgcctgtcg gaatccccca ctcatcaaca tcgaaacgca tcccggaaga
    25141 aggaagcctc ggcctatgat taagcaccgt actatcacta gcatcgctgg tgctggcatt
    25201 acccctaaac ccatcaagat taaagaaaac ttgctgacta aaattaattg ggcctgcctt
    25261 gagcaacggc gtaaccccga aggcaatccg ccactcatac ggcgtaaccg tgtgcgtcac
    25321 gcacgaggcg aagatcccag ggaacccatt ccacctgtta tcgaacagca cgaatgtaat
    25381 gctgttgctg atatgcactg cgatgtccca ggtctgtcgg ccccagcctt tatctccgcc
    25441 gttgaagagc gaggtcgcgt tattgagcgt ttgcggttac ggggtagatt gttccgtcga
    25501 ctgggtagct ggagttgctt aggaagccag cgtatcgtcc tggttgttcg cggaatcagc
    25561 ttattcaacc ggcaaaaaaa gcaagagagg ataaagtcga taacacgcac ctataacccc
    25621 atttaaatat ggatttgact gaagggacgg ataacccctc gcatagtcca agccgagtaa
    25681 aacatcgacc tcctcgccat gggtattatt cagccagaga tttgtaaggg ctgcgccatg
    25741 gtttgtaaaa gccagccgaa tgccttcgga ttgaatgata aatttgccct cttcatttgt
    25801 tggccagagg gctgtgagtg cagcgaatgg gctgccgcgg gtccagacgg actttacagc
    25861 ggcgaggagt ccgactgaaa atttccagag gttcattgct gctctgcaaa tcaaatgtta
    25921 agcttctgac ctttttcagg atgactctat agcttatatt gtctttaatg catgtgattt
    25981 gttgctgacc ggtgactttc tgctcagacg gcggcatccc ctctaaataa ccctaaggta
    26041 gtcatctaac gctacggatg ttataccaac aatcctccag cctttagact tccacaggtt
    26101 gtacaaactt aagccttccg taaatgcctt ctgccgactt cttcgtctgc ccaaacttca
    26161 acctccccgc cgtatcagga ttcgcaagct cgatctcaaa cgtagacaac actgccgcaa
    26221 caagacactc aagcgtcgcc ctggcaaaat tcgctccaat gcagttccgt ggacccgcgc
    26281 caaatgtaag catcgcataa ttactcgaag caccaccaga ctttgccttc ttcgcgccca
    26341 tccaccgctc cggatcgaac ttatccgcat caggccccca aagggtcttg tcatggttcg
    26401 acacctcggc cgagtacagc acaacagtgc ccttgggaat ccgctggcca ataagcatgg
    26461 tttccttttg tgcaactttt acgataatcg gcgagaaggg atagcaccgg agcacttcac
    26521 tgcagaatgc attcaagtaa ggcagattct ggacccgtaa tccaaagtta acggccgcca
    26581 gatctgtgcc tattgtcgct cgcagctcgt ctcttaaccg gctctgcatc tccggccggc
    26641 ggcctagctc gtacatcgtc cattcaaaag ccgtggcggt ggactcgtgg cctgcggtta
    26701 aaaaggtcat gacgtggtcg actagatggt gttcgtcaaa aacaccgcct gcgagagcaa
    26761 cagtgatgat atccttaccc ctgttgttct cagccacaac cagctgctct cttctccctt
    26821 gaataaccgc cgtcgtgagt tcacggaggt acttcgccga ttgcgagatc tcgatcaact
    26881 tcttaagcgg caccctcatc aatagtctca tgtcgaagta ccgactcagc agccccaccc
    26941 agctaaacac gcgagtcggg tcgaggatca gtttcctgtg gtggctgcgc aggtcggtat
    27001 cgggctgctt gagcgtctgg aaatcgtggc ccatccccgc cagcccgatg ttattgagtg
    27061 tagccctaga catgtactcg cggaagtcga tccgggcgaa ggagtctgcg cggagctcgt
    27121 tcgacatgca gcgcaccatt tcctgagctt tggcccagaa gatgctggtt aattttcgga
    27181 cgtgcgggac tgtgaatgct ggcatcatgt ttttgcgatg gagctgtgtt ctctctgatc
    27241 agctactagc ccaggggcaa tgtgttgttt acatgccttg aattcatcat tgctaaggaa
    27301 accaagattg ctacctgtga atcgtctgat agcaatcttg acgaggtcct ggtgggtgaa
    27361 gtcaaaggca ttgactgtga gcatgtctct gatggctggc gggcttgtca ccaggagggc
    27421 ctcgccgctc aacgcagagt agattcggag gagaccgtcg ttaggggtgg tttcggcaag
    27481 ttcccgcaga ggaacccatg cgttatcggg gaacaggact gggtagttcc ctgtcagaat
    27541 tcttcgacgc tactgtatgt cagctttgtc tttgtccctg tctatcgcga tgcgatgtga
    27601 cgtgaatacg caccgaagga gtggggatgt tgccgaaggg ggtaaaataa cgggggtaga
    27661 ggatcatcca atacacagca aaggcaacaa aggcaaccac atgagcacct agcacttgga
    27721 aatgcaatgc tgtatgctca ccgccagcga gagcctggtg gaagattccc cccgaggcta
    27781 gtgtaaccgt acacagccat aacccgagaa aggagatcat gctgaagggt tgctgaaaaa
    27841 gaaactgagt gaatagcttc tttaatagat gtggcatcac tttatccagc tactcaagcg
    27901 tgtgtctttg atacagagac tggatattag ccattcttat ttcttgcagg ctggtggcgt
    27961 gttagctgcg ccggtggtga gcccaacaga accggtgact tcttgcggat ggagaaaaca
    28021 ggcatgcaga catgtgccga ttacactaag ccatcgatcg gtatacttca gccacgttgc
    28081 tcgaaggcca taccctatga tctcgtaaac aacggctact ggttcgatct ttactagcaa
    28141 taggcaatgt aatagtaaaa gctgctattt tgggcgaaaa caatgattta tgtattattc
    28201 gattacctag gcgcaatgga cagctgtagt cttctgatgt gtgatgcgtt ttcactgagg
    28261 acaatcctga tgtatatgca gcctaacaag gatatggtag aagacattga tatcatcaaa
    28321 cgcgacacac cagcttttga ccagaaactt tcttttcctt aagaagccct agaccgccca
    28381 acgcctcccc aagactgtcc cctactaatt tatgcggatg cgtcttcaac ttcccttgat
    28441 ccagccaact cctgcaccag cttaaaccac ttgaacccaa accttctgta ctcctcgttc
    28501 ccctccccac caaacggctc tggccagtta agccttttcc ccagcagcgt cgggccaagc
    28561 acccaatctg gcacaaccgt cttcggccgg gtatgtagga acttagggta aggttccaat
    28621 gcggtgtatt cccccccccc cccccccccc ccccccaccg gccgaggcat ttgtagcaga
    28681 actgcattgt ctctggctca gaaatgcagt cgaggacgaa tttgagtgag tttcgagtgt
    28741 acttgcggat atcgtctgcg catgtcttct gacggtagtc gaaggcagca gtggcgccgt
    28801 aggatttcac gaggtcgaac ttggtcggtg agcaggttgt tatgggattc aggcccgatc
    28861 tggaaggtta agttagtagg tatttacttc taagagaata acagactgat actgtaacgt
    28921 acagtttgag caactgaata gccagagtcc cagtcgcagt gctcccacca tacaccagca
    28981 catccaccgg tttgtcagcc ggcaaccaag gcgatccagg aacatccagt gatttaaaca
    29041 gcgcaagtcc aatagtccca atcccacttc ccagggttac tgcttcttca agggacatgt
    29101 attccgggat ctttatggca gtaagatccg tcgcgccaac atactgcgca aacgcgccca
    29161 ccgcaggagt gagagagtgc atccaaggca ctgcgccgca gattcggtca cccggcttga
    29221 tgggtgcggc ggtttggact ttgggcccaa tggagacgac ttcgcctgcg aaatcctttc
    29281 cggctattgc gccaggactt gcaagcttgc cgaccatttt ggtgtcaatt gggtttaggg
    29341 cgacgaaggc gttcctcact aggatcatgt cgtcttctag tgatggcatt tggacatcgt
    29401 tgcgtaggcc gagtgtacca tcatcgctct cgatgatggc gggttgactg gacggtagct
    29461 cggacatagt aggaaaataa ataagtagca ggaaaaggaa aaagacaaaa aaattagcga
    29521 cgaaattcca atgcttgatg tgctgctggg aatctagtaa gcatcagtaa ggaccatggt
    29581 tatggtgagg atcgaaataa agcctccact cgccagagtg gaggatcaac agaaactcac
    29641 tcataaatcc atatttttta gtacgtaggc aagctccgga acttttcaat cgttcgatta
    29701 agttgccggt cctcgtatac caaccggagt atattttgcg tcttgtcgtt acggctccca
    29761 gccggccttg gccatgctct ggcaacatct gttcgcgcac ggcgtactta ccgctagtga
    29821 ttttgtatct tagcataacc agccgctttg atagcattgc tgtattatgc tgtatatata
    29881 atgtgagaat tgtagagaag tggtttgaca gtcaggacac aggatttcac tcaattttgt
    29941 tgatcagcta tttggatcga agcatctctc ccctccatcc cacaatgcaa cccagtagaa
    30001 atgaaccaat cgccattata cgcatgggct gccgtttccc aggtgaagcc agctccccct
    30061 ccaaactctg ggacctcctc cacaacccgc gcgatgtcgc ccgtgacatc cccattcaac
    30121 ctcgaccgct tctaccaccc aaccggcagc catcacggta ccaccaacat ccgccaggcc
    30181 tacctccttt ccgaagacgt gcgcgcgttc gatgcaaaat tcttctccgt ccccccaggt
    30241 gacgcagagg ccatcgaccc gcagcagcgc ctgctcctcg aagtcactta cgaggccctc
    30301 gaatcctcag gccatacgct ggccgacctg tccaactcga atacgggagc cttcgtcggc
    30361 ctcatgtccc aggactactt cgcgcttaat ggccaggatg tggactccgt ccccacttac
    30421 gctgcgtctg gtacggcggc gagtaatgct tccagccgac tctcttactt tttcaactgg
    30481 catggcccgt ccatggcaat agataccgcc tgctcatcta atctcgtcgc tgtgaatgag
    30541 gcagtccaag cccttcgaaa cggcacgagc cgcgtcgctg tagcttgtgg gacaaacttg
    30601 tgtttgtcgg cgttcacgtt tatcacatta agtaagctca gtatgttgtc accgacctct
    30661 cgatgtcaca tgtgggacgc cgacgcagat ggctacgccc gaggtgaagg tgttgcttgc
    30721 gttgttttga aaaccctcag cgatgcgatt tcagacaggg accctatcga agccgtgact
    30781 cgggaagtgg gcgtgaatca cgatggcagg acgaaggggt tgacaatgcc aagtgctaag
    30841 gcccaggcgg cgctaattcg aaacacttat gcccgcgctg ggctggatcc aacgaaggag
    30901 gctgatcggt gtcagtattt cgaagcgcat ggcacgggaa cgaaagctgg gtaggttgag
    30961 ccgcagacat ctactgtcag aaactgaaga tactaagtgg ccccattttg ggaccctcaa
    31021 gaagccgaag ccctgatgag agcgtttttt ccacagtctg actccgaagg cgaactcttc
    31081 gtcgggtcta tcaaagccgt gatcggccac accgaaggca cagcgggact ggcaggtctt
    31141 atgaaggctt gtcttgctct tcgcaatgca accttccccc ccaatttact ctttaataaa
    31201 ttaaaccctg accttgaact gttcacaagt catctccgtg ttcccacggc caaccaacct
    31261 tggcctgaat tgtcagatgg tacaactcgc aggctaggtt agctgaagat tgtcagaccc
    31321 cttggataac agctaattgt gtgacaatag tgtcaacagc tttggccttg gaggtaccaa
    31381 cgctcactgc attcttgaaa catacaatcc accaacagcc agtgacccag tcattgaaat
    31441 agacatggcc gcatcaggaa catgctgtat tccatctgta ttctctgcag catctgatag
    31501 atcattggcg acactcttgc agtcgacact aaaattcatg gacgagaata ccgacgttaa
    31561 catgagtgga ctggcatata acttgagcac caagcgatct gccctgcagc gaagacttgc
    31621 agtctccgct acatcgatcg acgaacttcg cgacaagatc aagtccacga tagaagccgc
    31681 gtcagagaat gacgccactt tgcactccac ttctgcttta cccgaacctg cttcattgct
    31741 tgggattttc accggccagg gcgctcagtg gcaaggcatg gggtcccagc tgatatcgtc
    31801 gatcccgtta gcccgaagaa ccgtcgaaga gctggattca tctctcgcaa gcttaccatc
    31861 ctaccaccgc ttatcctgga ccctagaaga ttgacagcac tacccccgtc ggtaaagcct
    31921 ctctttcgca gcctctctgc acggctgtcc aagttatcct ggttgacatg ctccgcgctg
    31981 cgggagtcaa gttccaggcc gttgttggac attcctctgg agagattgct gctgcctatg
    32041 cggcaggctt tatatctgca tgggacgcta tccgcattgc ggactaccgg ggattctacg
    32101 ctgaaatggc ggcagcgcct ggtggggaaa agggcgcaat gctggctgcc ggcacctcct
    32161 ttgaggatgc tagcgacctt tgccagcttg atgactttgc cgggaggatc tgcgtggctg
    32221 ctcataactc tcctagcagc gtgactctgt cgggtgatat cgacgctata gccttggcac
    32281 ggagggtgct tgaagaagag gagaaatttg cccggcgatt aaaggtcgac acggcatatc
    32341 actcgacaca catgcataaa tgctctgtac cttaccttac ggcattgaga aactgcaaca
    32401 tacaagtgca gcagcccggg cccgatgcac cgcagtggtt tagtagtgtc cgaaacggtc
    32461 aggtcatcag cagcatggaa agcttggaca gtcaatactg ggtcgataac atggtacagc
    32521 ccgagctatt ctgcccagct gtccaaacat gcttgaagta tgtggacaaa gccatcaact
    32581 gcgttgtaga ggtgggaccg catcctgctt tgcagggacc tgcgaaggat tctattcttg
    32641 ccgctgtgga tcgggagatc ccatatactg gcaccttgaa ccgtggaaag agcagtacgg
    32701 tggcattttc cgacgccctt agattccttt ggtgtctgtt tggctctgct gctgtgacgc
    32761 tcggagcgtt ccagcaaaca aattacccgg atactccgac tacaatgacc cgcggtcttc
    32821 caacataccc atggactcat gacagggggt actttgccga atcaagactc atcaagacct
    32881 ttcacaacca cccgttgccc ttccatgact tactaggaat ccagacggca gatggagcaa
    32941 gggaggaatg ggggtggcgg aatatcctga agatgaacga actcaagtgg ctgtcggaac
    33001 actcggtata aggccaagtc gtctttcccg caacagctta catttgtctt gccatggaag
    33061 cagcgctgca actggcccaa gggagaccag tgaaatcgat cgatctcttc gatcttgaaa
    33121 tccacaaagc tatcgccagc catgactcca caggcaccga gctccttaca tccatgacca
    33181 aggtgtctgc cctcgacacc gagtgggaag aaatcaccgc tgacttctca gcctactcca
    33241 ctataagcaa agacgctgcc aaccttgggc tgaactgctg cggtcgtgtg cgtgtgcttc
    33301 taggagaggg cgaggactcg ccttcccact tctcacctag acttccccca ctcggaaaac
    33361 tgaccgcagt agacgtggat agcttctaca agatcctgcg cgatgacttc ggattcggat
    33421 acgagggccc cttccgcgcg ctcacgaata tgtcccgcaa aaccggcttc gcaacaggca
    33481 cagttcggtg cgagaggttc gacgactctg aaacgtctct gctcttccat cccggtatgc
    33541 tggatagtgc cttgcagggt ctgaacgctg cccatagcgc cccaggagat gaccggctct
    33601 ggacgatcgt ggctccgacc ttctgtcgtt gaatatcgat catccctgga ctctgcagca
    33661 gcaatatgac ggataatgtt gagatcgact gcaatatcac tgatcctcgc gatacgcaca
    33721 tcactggaga tgtggaggtc ttctcggagg gtttcaggga gaagattatc gaggttgagg
    33781 ggctcacctt ctccccgttt gcgagcgcaa ctgttgagaa cgaccggtgt gtcttccagg
    33841 agtcgtttct gtgccatgct aagccgaacg cggacgttat ctttggtgat agacaggcaa
    33901 cccccgagga gagcaggaag gccctcttcg ctgagcgcgc ggcgttttac tatcttaagg
    33961 cttccatctc tcggtcagtc cggagcagcg cgaggccctt ccatggtatc ggcaggcttt
    34021 gctgaagaac gctgagctgt tattacacct tgtcaatgac gggaaacatc cgtttgcccc
    34081 gcagaattgg gtgagtgata ccagagagga tatattcaag atgatggaca gctatcccac
    34141 gacagacgcc gatttcaacc tgaccaaggc cgtcggcgaa catcttcttc tgccttcggt
    34201 gctgaatgga gatacaagca tcctacaata catgaccaag gataactacc ttgagcggta
    34261 ctacgtagat gccattggat tccagctgct taacttcttg attgccgggg tgatggaacc
    34321 gctttgcttg aagtctcccc gaatgaactt ccttgaagtc ggagccggaa ctggaggcgc
    34381 gaccaaggcg atcctggaga agatcggtta ctcctatgcg tcttatacat ataccgacat
    34441 ttccagtgcc ttctttgacc atgatgcggg ccactttcaa tcccacgcca gcaagatgat
    34501 tttcaaggcc ttggatatca caaaggaccc cgccggacaa ggcttcatcc cgcagagcta
    34561 tgatgttatc gttgcctcca atgttttgca cgcgaccgag tcattgagat ccgcccttga
    34621 acatacacga aggctcttgc gtcctggtgg ttatcttgtg atggttgaga tcatccgcaa
    34681 cgacgtaatg cgccatggtc tcgtcatggg cggccttcca ggctggtggg tcggtgagaa
    34741 cgatggccgt tacggaggcc cgagtattac tcttgatcaa tggcataaaa tgcttcgaga
    34801 gaccggcttt agtggtatcg agactaattc gcccatgagg gacccagtcg gcgtgcccgg
    34861 atcgattatc gtttctcggg ctgaaactga tctcgtcacc cagttgacca ggcctcttag
    34921 ctcaaagttt agtacagcaa cagacaaaac tccattactc attataggtg gtatcagtcc
    34981 atttgtatcg ccgttcaggg accagatctg tctcaccctg aggcggcatt tcggagacat
    35041 cattaaagtt gagcagttcg cggatctgcc accgcttcct gagtgctacc atgtcctcag
    35101 tctcacagag tgcgacgcaa acttgttcga ggacatggag gagtctgtct tcttgaatct
    35161 gaagacagtg ttaggctctg cactgagtgt actctggttg ctccgggatc gtcgatcaag
    35221 taatccccat gccggaacta cgcttggtct tttcagaaca cttttttacg aagttcccgg
    35281 gactttgttg cagactctgg atattgacgt cgtcaatatg gacgactgct cagtcattgc
    35341 agaatcaatg tgccagctta ggttccagtc ggacatggcg agacgtggtg agacggatga
    35401 gatccgctgg gagtttgaac cggagcttgt tctcaaggac ggcgagcttt atgtcccaag
    35461 agttcgtccg catgatgggc agaataatcg atacaactcc tccaagagat taattactca
    35521 caatgtggac gtgcacacga ctcctttggc tctagatctg gtcgacggct cgtacatggt
    35581 aagagagcag cacaccatag agaaggactc acccgaagtg gctacagtca atgtctcctg
    35641 ttcattcttg tcgtcaataa agactcccgt gggatatgta ttcgttagcc tcggagaaaa
    35701 tgtcaagact ggcgaaaaga cactttgctt caccaaccat aacgggtcca tcgtcaaggt
    35761 ccacaaatcc tggacaatat cccttggcga ggttgaggtt gacggataat tcatctcgtt
    35821 tgtcattgcg gatctcacag tccaatgggt gttgcaaatg ctgccaccca caggaactgt
    35881 gctggcttat gagccagatc cagttgcagc atctctgctg tcttggcatt tgaacgggct
    35941 tggcaggaag gctcttttca tgactttgag tccggaaatg tgcggccgaa actgggtgta
    36001 ccttcatcct aacagcacca tgagagccat cgctgctaac ttaccagccg acgtcaccct
    36061 gtacgtcgac gcctctggag ccggcgaatc tccttcccaa agtctcggat ccaagattgc
    36121 gacctcccta tcatcagtct gtaacaaggt taagatgtct agcctgactg catcagaagc
    36181 atcctttctt ccgcacgatg cccctaaaac catcacagat ctattccgtc acgttgcttc
    36241 cttcgcttcc tccttggtat ccactcaagc aactccagag ggtgcaccac tcgatatctt
    36301 accgctcaaa cgggtggctg cgaactttgc gatgccaaat ccccgctcgc ttgtttactg
    36361 acgagaggat caatatgttc cggtctctgt tgagccggtt acgcaacgtg gtgatctgtt
    36421 ccgtcctgat cgcacctact ggctagctgg tctgaccgga gacactggac gatcactggc
    36481 ggacttcatg attgcccaca atgctcgcaa tattgtgcta agcagccgta cgcccaccgt
    36541 ctacgaggac tgggtagagt ggcacaagtc aagaggtgtt tcagtgaggt atttcggagg
    36601 gtaagcaaaa gtactcgtcc gcttgaaact tatcatcgct taccagcctt tcttacttag
    36661 ggatatcacc agctttcagt ccgtgaaaca gatccatgac gctatcaagg agtccatgcc
    36721 gcccattggc ggcgttgcaa atggcgccat ggtgctgcga gacagttcct tcatgaaagt
    36781 gagctttgac gatttccaag cggtcttagg tcccaaagtt aaaggcacaa tcaatattga
    36841 ccggctcttc tccgatccca accaactgct cgactggttc attgggttca gttcagttgc
    36901 cggcactgtc ggcaacccag gacaatcggg gtacacagct ggaagttgtt tcatcaaggc
    36961 acttgtcgac cggcggcgta agcaaggcct ggctggatca gtcattgaca tcactcgatt
    37021 ggtggggttg ggcttcatcg agcgtgaagg cgatggccgt ctgacaaagg agcaccaaga
    37081 gcgtctaacc acgcggtcgg ggaccattgc gatgagtgag aatgacctgc accagttgtt
    37141 tgcggaggcg atcttggctg ggcgaccgga tctcgatctt aacccggaga ttattacagg
    37201 tctggcgccc atcactgttg agcagtccaa ggatacatac tggaagacca atccgaggtt
    37261 gtcgctgttg atcagagagg caggacaggg tgatttaaaa ggcagagacg ggggcaacgc
    37321 ggctcctctg agacaattgt taggagacac aaagacaatg caaaacgttg cgaatgtgct
    37381 ttcaggtgcg tgaaatttgc ttcaataccc cttatccggc ccctgacaag tctgtttagg
    37441 tgccctcaaa ggaaagctgc aagcgttgaa attcctgtcg gactctgaca gcttgtacga
    37501 cactacgcct ctggtggaca tgggtgtcga cagcctggta gctgtggaag taaggtcttg
    37561 gttcttgaag gagctcacag ttgacgtgcc actcatgaag attctgggcg gcgcctccat
    37621 cacggatttg gtagaggttg tcgtgcagaa ggttccccgg gagctattga gtcggcttga
    37681 tcccgaaggg cggcgtcagg acagcaatgg cgatgttcct gctactgtgg gtgacaatga
    37741 ctctgttgaa acagtgggat caaagatgaa tggcattaac agcgctcatg aaaatggttc
    37801 tagtggtgtc aatggtatca gtggtactta tacacctgat atggatagca ctacagacct
    37861 taatggtact aatggggctg cagttatcaa ggaaatgtta gggcataaag ccataaaggg
    37921 tgttgttcca atccttctca atgcacagga ggttgcctaa gatgaaagat tttatactta
    37981 tgtttgataa tattagttct ctagatgttc tgatctatag actactaaag ataatcaaat
    38041 tcctattctt acaagttatt ataagcctac tgctttcaaa tttaagactt agaataggtc
    38101 ctttaccctt tattcagtga cattaacaca cacgcctcct aatatttgga tatgatttcc
    38161 aagaagagtt agaattgagc ctcgatattt attcacttcc tcaaagatca agctgttaaa
    38221 attataattt ataataggga ataggtgatg aactgatata gctggggtct aagctcgcat
    38281 ctcacactat gaatctaaca tctgtgtgat tggtttcatg aggctagtta gacacttaga
    38341 ctatactctg tatctgtagt atataaaccc aaaataacct atatagatag cataattctg
    38401 catggcataa ataattgaga atgagagtcc ttgtatgtat aaagtgactg aaaaattaac
    38461 taataaataa ttgcaattta caaacatcct attaatggtt gctaacactg gattcaactg
    38521 tttagttatc tagcctgtgt ccccgccaag caataatatt tctttaagag ttagccttcc
    38581 tgtttggctg gtctgcatgt ctccccacag atacttgatg catgctaatg cactatcctc
    38641 agcagctatt tctataagat cttattcctt actgttgacg tgcatttgca ttacagtccc
    38701 aactatagaa acagcaatta tatgtaagtc atgcttgaat gctcaaaaat agagccgaat
    38761 cctgtggttt gaccatgatg tgtggagtgc tccactacat cacacatttc ctaggtctca
    38821 aaatggtaga atttaggaat gttggctcct gcacatggca aagcagatca aacaccaaca
    38881 ctctcctcta tggcttaaga atgaatcatg tgactgaaca gaagggttcc attaccagat
    38941 tctcaccgcc aaaatatccg ccaaccagaa tatgccaatg atcctccaaa aaaaatgtat
    39001 cttccatcta gtatacagag tacagcacaa cacaacaact tggaacactt ccaagggagc
    39061 ttctccccca tccgggaagg gatccgaagg agttccttgg cggtggatca aaatgctcca
    39121 tttacgcatc cgtccgctcc cccgtctcca accggcatca tccatcccca cccagtctgc
    39181 ccctccttcc gacttccaca atgaagacaa cagcaacgat gacgactccg ctgaggacct
    39241 cttctctgcc ttcctccctc atcttttccc cgacgacgcg ccctccttcc atggagaccc
    39301 cggccagcgg ctcctgtaca cctccccgcg ctacggcgac ctcgagatca tggtgccctc
    39361 atacccgagc cagagcgagc gccgctcgga agagatcgcg gctggcctgc cgtcagaaga
    39421 tggcagcgtg aatgccgtcg acgagggccg caagctattt gcgcattttc tctggagcgc
    39481 tgcgatggtg gtcgccgagg gtgtggaaaa ggccgacacc ctggccacgc gcggtgagct
    39541 cgacgctgac acagccatgt ggatggtgcg cggcgagcgt gtgctggaac tcggcgctgg
    39601 cactgcgttg ccttctatta tatgtgcacg tgcacacgct gctgctgtca ccatcactga
    39661 tcacccatcg tcgcctgcat taaccggtgc tattgacttt aacattcgtc gtaatctagc
    39721 agcgacagaa gcagaagtca tgagccagcc gcatgaatgg ggcatgctgg aaccagaccc
    39781 gtgggccgtt gcgcaccgcg gtgccttcac ccgcatcatc gcggctgact gctactgggt
    39841 gcgctcgcag catgagaacc tggtgcgctc gatgaactgg ttcctggcgc caggtggaaa
    39901 gatctgggtt gtggcaggat tccacacagg gcgcgcgatt gtagcatggt tctttgagac
    39961 ggccatgcag aatggactgg agattgagcg catctacgag cgggatctta ttgccaccag
    40021 cgaggatggg ggcgaggtgc ggcgtgagtg gatgcctgag cgtgaaggtg aggggccaga
    40081 gaatcggcgg agatggtgtg tggttgctct tttacaaagg agagagtaat cttttgtttc
    40141 ttgtatagac gtggctccca tgattaatga gtatatcatc ttccatacca agtcctgagc
    40201 tttacctaga cacactgaaa gcacattata caaaaccctg cccttaaagg cgatttccag
    40261 atccctggcc tcgtttcctg ccggcaggca aaggcatgaa aacaggaata tgaagacccc
    40321 atcaacatca ttgttaagaa actcagctgc gtcccgacct aatcggcctg ctcttcctca
    40381 cactgagtag ggacaacatc attttcgaag atgccagtgc tgtctggatt cgtgcctttc
    40441 aagagtatga acctgctgtt tctgtgttcc ggtgctccct catggcacag caaccgactt
    40501 ccaatcagcg acgggctttc aatcctgtac cagtcaaaac aaaccgagaa tcgacggact
    40561 tgattagcaa tttattcact aatttccgca ctgtgtacct tgatgatgac actcgaacag
    40621 agaatgaata atcccctgtc tcttctctac cattatatat tatgtcgtga ctcggtgtgc
    40681 tccaatctca agcagttaga tcttgataaa gccatgggat atagccaact tactgtaata
    40741 gaataaggtt ccttgcctct gatctggtag atgaggctgt cctctggtca cagaaacata
    40801 atacgccaag ggactctgag aacacagtac ggtatatggc acatacatgc gagatcgtct
    40861 tgccgggacg ccatttaaat attaagtagg ccccttggtt tggtcttcct aacatgtcat
    40921 tcacaccttt cttctctccg aagccgccag gatgctaacc ctaaccaccg agtcgcttac
    40981 aacaacgttc cctagatata tctcttcacg taacaatagg tatggtgcac ttccacaaaa
    41041 gtgcacaact agcgcaactt caaatcttgt atagttaatt ttcaggtttg atacaacact
    41101 ggctgtattt tattttgccg tgcaagcctg tagcaactaa ccatgttatg ttctaatcct
    41161 tccagtaaca tatgcattgt cattgccacc cttcttcctg tagtattcac ccaacctgtt
    41221 gtatggttcg ttgaaaagct cttcaactgc cttgccttcg agggtcggcg ttcgaataat
    41281 cgcgatcagc agtcttgcct tgactagatg agcatatcta gacaagttga aggtaacaaa
    41341 atctaacagt ctcaaaaaga gcaatggtca gccatgactt ccataattaa aagcaaaatg
    41401 tggtacttaa atagagccaa aaaccaatca ccagatttca attcaatgtt ggccccttgc
    41461 cactttctgc tcgcccaaaa ggatggagta cgcccttagc cagtatactc tacgtagcca
    41521 aaggtaagta atacatattg gatgaaaagc aaaatattaa aacaaataca cgaagaaata
    41581 tctctaatag ttttcttata atgcttagca tctccaacca tcatccagaa tattgaaatc
    41641 cgactcctga agtaacccca ttataacccg attactagag aaccacccat ccaacgccgc
    41701 ctcatttccc atccacatca tcggctcctc tctttgctca gatccttgtc tggtaaaaac
    41761 atgtctagga tctgtgccca gagactgcga ttccgattga tgatcatcga ctgaaacagg
    41821 tgctgacagt cccaatgcag cgagatgctc atccatctcg gcacacgctg gtgtctggcc
    41881 tggtttctga gatgtgcgga gctctatgta gcgcagtgct acgttgtaga ggactagaaa
    41941 gagatggtac accctagcag cagcatctga gactgttggt gctaatttga tggagtcaac
    42001 gaagtcgtgt aggggagata ggtagctttg gtcttgggtt tcgattacgt ggcaaaatat
    42061 gacaatgaag ggggaaaagg gtgcgaatag gagggtcctt caaagcgatt aaaagacgtt
    42121 agtgccttcc gacgggatga ggcgggatgg gggcttcatt cgcccattgc ttcatctgga
    42181 gatacagtct taccaatgaa tatacttggc gaagtagata ctgccattct tgcgtatcac
    42241 atcaataacg tcatggtgtc tccttaaagc ggtctcggca gctttgatac agcttaagct
    42301 aaaggttgtg gaggatcctt ttgtgggcgg agcggcccga taaaccaggg tgaggagcga
    42361 aagacggagg tcgtcgtcag acaaagcgaa aaagtttacc aggtcttcac cagaggtctg
    42421 gctggcagtt ttaatccatt gattctatgt tatattagac tcggtcattg atcggcccat
    42481 ttgtgactta catgggtatt gcgagttgcc ttttccaatg cctgaaggtc attcacaagg
    42541 atttgcactc gatcgtgccg cactgagtcg ggctgggtaa gtgaggaggg gctgtatagc
    42601 atggcgtaca tgttacccta tcccacaagc cgcagacgac catgggcatg gttggtttag
    42661 ggtgtaggtt ctgattggct ggttaggccc cacacctgct catggtcggt ttggaaactt
    42721 aagggtatgg ttggtttact tctagtcacc cagtgctgct taaattttat aggatgatag
    42781 agtagccatt tatttcttac ctagctaagt ttggggttta taggttcata atcaaaggtg
    42841 tggtgtgggt atgaaattcc caggtttgaa ataatcaatg ttggtagggt atcacccgca
    42901 catgcatgaa attcaggggt aaaggtattt tgcaatcatt catatttatt catattcatt
    42961 catattcata ataatcacca tggaaaatca attatttcat aaattaccta ccctaggtat
    43021 tagggtttgc catcaatgta agcatgtatg ctgctcgcag tatcctcagt cgtgtgtcag
    43081 tatcctgtcg aagagcagag ggtcttcgcc catttcattg tgagactatt ctcctggaga
    43141 tgtataactt gacattgagt actgagtgcg acctgcagag gtagaacagc atctaaagaa
    43201 gaagcattac ctaaagcatg cagtcactag ccagatcacc caggctatct cttaatggca
    43261 tgatatttag catgatagtg ctgctatcca gatacctcat gcactagatg agccactacc
    43321 tatattacca tctcattcta atggcctgct ctgccagtga gatccttatt gcttattcat
    43381 tacctctatc atagattcta tgcataagca ctggcgaact atccactagt agtcttagca
    43441 gacccatcat aggtaggtag gcccaaagga gaaggctagg ggggaggcag agctatagca
    43501 gttattctaa tatgtcttat agcagtaggt attccctagc agtccagggt cctactatat
    43561 catatccact atccagaggg actgccaccc ctattaaccc agggcatgca ggctgcagtg
    43621 gatgaggtgg tgcaggcctg ggagcaggcc taggcccagg cctaggctga tcaggccatc
    43681 caggccagcc agttgactga tgtgaacccc tggctgcgca tgatgaggta ggccaactat
    43741 ctgcagggca tccaggccca tgacctgcta gcctgcgtgg cagccctaga ggaagacccc
    43801 atggacgcca ctaagcaggg ggtgtaagta atctgggata ccatagagca ggtagcctgt
    43861 aagagccagc agatagtcta gcattgcagc caggccatct gggtagaggc tatctagtct
    43921 gaaaaagggc agaccccaca ctggctgtta ttagcatata tagataaggt agtaatccag
    43981 aagcatgtct gtctatggta gcagatacta gcatttatta tctaaacata ggccccgcat
    44041 gactagacca gcctaaaata tgggatgacc acctagtagc actagaaatg gcgccagtta
    44101 tagcagctag ctagccaggc cctaggcagc cctgaccctg acccccaggg tagccaggcc
    44161 acagtcccag gggacctaga ggtatgggcc atgactgcta tagaaaaagc atacttagaa
    44221 ttttatatta agctacttaa ctagcgccat cacagccata aatataagag tgtattagta
    44281 tgcaccatgg ctgtgctggg ctagggtaag gctggctaac acaaccctaa gagctacccc
    44341 ctaatattat cccacatgat caaggtagcc taattcatgg tggtgcagaa ggtattatag
    44401 atagacccta atctatagca gatcattcag acctaggcgt ggaaggacta gagcactgaa
    44461 tgggtgctag ccagcgcgga taattaactt agggagattg atgagggata tagtagtaat
    44521 aaccccctat ctaccccagg gcccctatca tcgcccctgt tatccatcca tagtgataac
    44581 ctattgcctg tggtgaatat tcaccatagc tgccggccat tccaggagca ggtgacatgg
    44641 ataatacact agtttatggt ctgcgggacc catggcctta tagaaatatt actagactag
    44701 tgcatatata ggttaaaggt ctattataat tatacagccc ctggctatgt gatatagatg
    44761 ggggaggacc aactgttata ctagcagatg gcattcacta taggtaattt tcaggggttt
    44821 atccatggac ttatgactgt agcttaggag atactaggct atttatacat ataagattat
    44881 acacagatgc ccgccattct atggacagca ttatataatg atcctagcca gagctaggct
    44941 gggtggaact ttgtgcagga cgcatggacc tagtggccag tgaataggac ccactggatg
    45001 atcaaccagc tgtgggctga gctggctatg tagtggtatt tcctgtaggg gggctgattc
    45061 caccctggcg ctatccagca gtattggcag cgcgtggcct agttcaagga gaaattggcc
    45121 attatcatgc atgccactgc ggggcagctg gcctgggccc cagagttatt aagcattcag
    45181 cattgcaaca cagtgaatag tcgccggcgg aatatatata ttaaggatgg catggtgacg
    45241 tttgtgatgg catattataa ggggttccat gctagcaatg atgttaagat catccattga
    45301 tatgtgctgc gagaggtcgg ggagttagta gtatggtata tctggctggt gatgccattt
    45361 attaaccagt tggctgcatg gcaggccgcg caggggagcc aggtagtgca gggtaaccag
    45421 gccgcgcaga gtaaccaggc ggcgcagggt aaccaggcgg cgcagcgtaa ccaggccgcg
    45481 caggggagcc aggcggcgca gggaagccag gctacgcagg gaagccaggc tacgcagggg
    45541 agccaggcgg cgcagcgtaa ccaggccgcg caggggagcc aggctgcgca ggggagccag
    45601 gcggcgcagg gaagccaggc tgcgcagggg agccaggcgg cgcagcgtaa ccaggccgcg
    45661 caggggagcc aggcggcgca gcgtaaccag gccgtgtagg ggagccaggc tgcgcaggca
    45721 tggttatggg gccccaaccc cggtaccggc cgtgaatggt cgtccgagtg gttccgggag
    45781 gcgttgaaac aggaaacccg cacccagcta ggcaccgcca tccatatcgc ggcataccgg
    45841 gacatcgcca ttggaatcag ccgctgattt ttgtggccgt ccaccgcatt ccccctaaca
    45901 ctataatggc ccatcagggg ggggggtgat catacaaatc ctagggttgg ccgggggggg
    45961 ggtgatcagg gtaagccatc accccccctt atctttatca attcttcata ttttttgatg
    46021 atttaaaatg atttatgatt ctaactagct accctattag attctaatat taaattctag
    46081 attaattact aggaaggtgg ttgaactagg ggggtagggg aaaggtcgaa attttttgtt
    46141 ggggtctgcc aagaccacta tctgcgggaa gcctataccc ttttaggcca ccatccagta
    46201 tagattagtg cctaaggcat cctatagact actagggcct tagaattcag gcagaaacta
    46261 taagaaaaat taattcttag tattcaccag gggcctagta ctagataact gattctaatt
    46321 atttttagtg aatagtagat acctttagct atagaatgat aatagtctga ttaggtaagc
    46381 atgattcctg attttttaaa aattcttaga agacaccttg aaatttatta cctgctgact
    46441 aattataatt atttttagta aatagaccta atttctacta gtctaatgat atatagcatg
    46501 cgtagtaata ttcagcctag aatttttaaa aattcataga agtaaatgtt tcgtggattt
    46561 catagagata tatagtaggg aggggtctca ctttagggtt agggttaggg ttagggttag
    46621 ggttagggtt agggttaggg ttagggttag ggttagggtt agggttaggg ttagggttag
    46681 ggt
//
